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2PPN
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BU of 2ppn by Molmil
Crystal structure of FKBP12
Descriptor: FK506-binding protein 1A
Authors:Szep, S, Park, S, VanDuyne, G.D, Saven, J.G.
Deposit date:2007-04-30
Release date:2008-05-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (0.92 Å)
Cite:Structural coupling between FKBP12 and buried water.
Proteins, 74, 2009
1PS8
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BU of 1ps8 by Molmil
Crystal Structure of the R270K Mutant of Aspartate Semialdehyde dehydrogenase from Haemophilus influenzae
Descriptor: Aspartate semialdehyde dehydrogenase
Authors:Blanco, J, Moore, R.A, Faehnle, C.R, Coe, D.M, Viola, R.E.
Deposit date:2003-06-20
Release date:2004-07-27
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The role of substrate-binding groups in the mechanism of aspartate-beta-semialdehyde dehydrogenase.
Acta Crystallogr.,Sect.D, 60, 2004
4FAP
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ATOMIC STRUCTURES OF THE RAPAMYCIN ANALOGS IN COMPLEX WITH BOTH HUMAN FKBP12 AND FRB DOMAIN OF FRAP
Descriptor: C15-(R)-METHYLTHIENYL RAPAMYCIN, FK506-BINDING PROTEIN, FKBP12-RAPAMYCIN ASSOCIATED PROTEIN
Authors:Liang, J, Clardy, J.
Deposit date:1999-05-06
Release date:2000-09-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Refined structure of the FKBP12-rapamycin-FRB ternary complex at 2.2 A resolution.
Acta Crystallogr.,Sect.D, 55, 1999
3AJX
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BU of 3ajx by Molmil
Crystal Structure of 3-Hexulose-6-Phosphate Synthase
Descriptor: 3-hexulose-6-phosphate synthase, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Kita, A, Orita, I, Yurimoto, H, Kato, N, Sakai, Y, Miki, K.
Deposit date:2010-06-24
Release date:2010-11-03
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of 3-hexulose-6-phosphate synthase, a member of the orotidine 5'-monophosphate decarboxylase suprafamily
Proteins, 78, 2010
1QF5
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DESIGN, SYNTHESIS, AND X-RAY CRYSTAL STRUCTURE OF AN ENZYME BOUND BISUBSTRATE HYBRID INHIBITOR OF ADENYLOSUCCINATE SYNTHETASE
Descriptor: (C8-S)-HYDANTOCIDIN 5'-PHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Hanessian, S, Lu, P.-P, Sanceau, J.-Y, Chemla, P, Prade, L, Gohda, K, Cowan-Jacob, S.W, Fonne-Pfister, R.
Deposit date:1999-04-06
Release date:1999-12-02
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:An enzyme-bound bisubstrate hybrid inhibitor of adenylosuccinate synthetase
Angew.Chem.Int.Ed.Engl., 38, 1999
2NSJ
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BU of 2nsj by Molmil
E. coli PurE H45Q mutant complexed with CAIR
Descriptor: 5-AMINO-1-(5-O-PHOSPHONO-BETA-D-RIBOFURANOSYL)-1H-IMIDAZOLE-4-CARBOXYLIC ACID, Phosphoribosylaminoimidazole carboxylase catalytic subunit
Authors:Ealick, S.E, Morar, M.
Deposit date:2006-11-04
Release date:2007-04-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:N(5)-CAIR Mutase: Role of a CO(2) Binding Site and Substrate Movement in Catalysis.
Biochemistry, 46, 2007
1NSG
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BU of 1nsg by Molmil
THE STRUCTURE OF THE IMMUNOPHILIN-IMMUNOSUPPRESSANT FKBP12-RAPAMYCIN COMPLEX INTERACTING WITH HUMAN FRAP
Descriptor: C49-METHYL RAPAMYCIN, FK506-BINDING PROTEIN, FKBP-RAPAMYCIN ASSOCIATED PROTEIN (FRAP)
Authors:Liang, J, Choi, J, Clardy, J.
Deposit date:1997-07-01
Release date:1998-03-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Refined structure of the FKBP12-rapamycin-FRB ternary complex at 2.2 A resolution.
Acta Crystallogr.,Sect.D, 55, 1999
1PR3
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BU of 1pr3 by Molmil
Crystal Structure of the R103K Mutant of Aspartate Semialdehyde dehydrogenase from Haemophilus influenzae
Descriptor: Aspartate semialdehyde dehydrogenase, PHOSPHATE ION
Authors:Blanco, J, Moore, R.A, Faehnle, C.R, Coe, D.M, Viola, R.E.
Deposit date:2003-06-19
Release date:2004-07-27
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The role of substrate-binding groups in the mechanism of aspartate-beta-semialdehyde dehydrogenase.
Acta Crystallogr.,Sect.D, 60, 2004
4C02
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Crystal structure of human ACVR1 (ALK2) in complex with FKBP12.6 and dorsomorphin
Descriptor: 1,2-ETHANEDIOL, 6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine, ACTIVIN RECEPTOR TYPE-1, ...
Authors:Williams, E, Riesebos, E, Vollmar, M, Krojer, T, Bradley, A, Shrestha, L, Kupinska, K, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.
Deposit date:2013-07-31
Release date:2013-08-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Crystal Structure of Human Acvr1 (Alk2) in Complex with Fkbp12.6 And Dorsomorphin
Ph D Thesis
1QZ9
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The Three Dimensional Structure of Kynureninase from Pseudomonas fluorescens
Descriptor: 3,6,9,12,15-PENTAOXAHEPTADECANE, CHLORIDE ION, KYNURENINASE, ...
Authors:Momany, C, Levdikov, V, Blagova, L, Lima, S, Phillips, R.S.
Deposit date:2003-09-16
Release date:2004-01-20
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Three-Dimensional Structure of Kynureninase from Pseudomonas fluorescens.
Biochemistry, 43, 2004
3AX6
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BU of 3ax6 by Molmil
Crystal structure of N5-carboxyaminoimidazole ribonucleotide synthetase from Thermotoga maritima
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Phosphoribosylaminoimidazole carboxylase, ATPase subunit
Authors:Miyazawa, R, Kanagawa, M, Baba, S, Nakagawa, N, Ebihara, A, Kuramitsu, S, Yokoyama, S, Kawai, G, Sampei, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2011-03-30
Release date:2012-04-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of N5-carboxyaminoimidazole ribonucleotide synthetase, PurK, from thermophilic bacteria
To be Published
1MC4
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BU of 1mc4 by Molmil
Crystal Structure of Aspartate-Semialdehyde dehydrogenase from Vibrio Cholerae El Tor
Descriptor: Aspartate-semialdehyde dehydrogenase
Authors:Blanco, J, Moore, R.A, Kabaleeswaran, V, Viola, R.E.
Deposit date:2002-08-05
Release date:2003-03-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:A Structural Basis for the Mechanism of Aspartate-beta-semialdehyde Dehydrogenase from Vibrio Cholerae
Protein Sci., 12, 2003
1MEZ
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BU of 1mez by Molmil
Structure of the Recombinant Mouse-Muscle Adenylosuccinate Synthetase Complexed with SAMP, GDP, SO4(2-), and Mg(2+)
Descriptor: 2-[9-(3,4-DIHYDROXY-5-PHOSPHONOOXYMETHYL-TETRAHYDRO-FURAN-2-YL)-9H-PURIN-6-YLAMINO]-SUCCINIC ACID, Adenylosuccinate Synthetase, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Iancu, C.V, Borza, T, Fromm, H.J, Honzatko, R.B.
Deposit date:2002-08-09
Release date:2002-10-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Feedback inhibition and product complexes of recombinant mouse muscle adenylosuccinate synthetase.
J.Biol.Chem., 277, 2002
1MF0
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BU of 1mf0 by Molmil
Structure of the Recombinant Mouse-Muscle Adenylosuccinate Synthetase Complexed with AMP, GDP, HPO4(2-), and Mg(2+)
Descriptor: ADENOSINE MONOPHOSPHATE, Adenylosuccinate Synthetase, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Iancu, C.V, Borza, T, Fromm, H.J, Honzatko, R.B.
Deposit date:2002-08-09
Release date:2002-10-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Feedback inhibition and product complexes of recombinant mouse muscle adenylosuccinate synthetase.
J.Biol.Chem., 277, 2002
1MF1
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BU of 1mf1 by Molmil
Structure of the Recombinant Mouse-Muscle Adenylosuccinate Synthetase Complexed with AMP
Descriptor: ACETATE ION, ADENOSINE MONOPHOSPHATE, Adenylosuccinate Synthetase
Authors:Iancu, C.V, Borza, T, Fromm, H.J, Honzatko, R.B.
Deposit date:2002-08-09
Release date:2002-10-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Feedback inhibition and product complexes of recombinant mouse muscle adenylosuccinate synthetase.
J.Biol.Chem., 277, 2002
2NQ5
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BU of 2nq5 by Molmil
Crystal structure of methyltransferase from Streptococcus mutans
Descriptor: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase
Authors:Fedorov, A.A, Fedorov, E.V, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2006-10-30
Release date:2006-11-14
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of methyltransferase from Streptococcus mutans
To be Published
2QZ9
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crystal structure of aspartate semialdehyde dehydrogenase II from vibrio cholerae
Descriptor: Aspartate-semialdehyde dehydrogenase
Authors:Viola, R.E, Liu, X, Ohren, J.F, Faehnle, C.R.
Deposit date:2007-08-16
Release date:2008-04-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure of a redundant enzyme: a second isoform of aspartate beta-semialdehyde dehydrogenase in Vibrio cholerae.
Acta Crystallogr.,Sect.D, 64, 2008
2R00
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BU of 2r00 by Molmil
crystal structure of aspartate semialdehyde dehydrogenase II complexed with ASA from vibrio cholerae
Descriptor: 2,2'-oxydiacetic acid, Aspartate-semialdehyde dehydrogenase
Authors:Viola, R.E, Liu, X, Ohren, J.F, Faehnle, C.R.
Deposit date:2007-08-17
Release date:2008-04-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:The structure of a redundant enzyme: a second isoform of aspartate beta-semialdehyde dehydrogenase in Vibrio cholerae.
Acta Crystallogr.,Sect.D, 64, 2008
2UKD
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BU of 2ukd by Molmil
UMP/CMP KINASE FROM SLIME MOLD COMPLEXED WITH ADP, CMP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CYTIDINE-5'-MONOPHOSPHATE, MAGNESIUM ION, ...
Authors:Schlichting, I, Reinstein, J.
Deposit date:1997-05-20
Release date:1998-05-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of active conformations of UMP kinase from Dictyostelium discoideum suggest phosphoryl transfer is associative.
Biochemistry, 36, 1997
2R85
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BU of 2r85 by Molmil
Crystal structure of PurP from Pyrococcus furiosus complexed with AMP
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE MONOPHOSPHATE, CHLORIDE ION, ...
Authors:Zhang, Y, White, R.H, Ealick, S.E.
Deposit date:2007-09-10
Release date:2007-12-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure and function of 5-formaminoimidazole-4-carboxamide ribonucleotide synthetase from Methanocaldococcus jannaschii.
Biochemistry, 47, 2008
8D45
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BU of 8d45 by Molmil
Cryo-EM structure of human Kidney Betaine-Homocysteine Methyltransferase
Descriptor: Betaine--homocysteine S-methyltransferase 1
Authors:Lyu, M, Yu, E.W.
Deposit date:2022-06-01
Release date:2022-11-16
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.62 Å)
Cite:Cryo-EM structure of human Kidney Betaine-Homocysteine Methyltransferase
To Be Published
8DU0
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Crystal Structure of NADP bound GDP-L-fucose synthase from Brucella ovis
Descriptor: GDP-L-fucose synthase, GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2022-07-26
Release date:2022-08-10
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of NADP bound GDP-L-fucose synthase from Brucella ovis
to be published
8DUJ
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BU of 8duj by Molmil
Global map in C1 of RyR1 particles in complex with ImperaCalcin
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, CALCIUM ION, ...
Authors:Haji-Ghassemi, O, Van Petegm, F.
Deposit date:2022-07-27
Release date:2023-05-31
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM analysis of scorpion toxin binding to Ryanodine Receptors reveals subconductance that is abolished by PKA phosphorylation.
Sci Adv, 9, 2023
8DVE
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BU of 8dve by Molmil
RyR1 in presence of IpCa-T26E phosphomimetic and activating ligands
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, CALCIUM ION, ...
Authors:Haji-Ghassemi, O, Van Petegm, F.
Deposit date:2022-07-28
Release date:2023-05-31
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (3.84 Å)
Cite:Cryo-EM analysis of scorpion toxin binding to Ryanodine Receptors reveals subconductance that is abolished by PKA phosphorylation.
Sci Adv, 9, 2023
8DTY
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BU of 8dty by Molmil
Recombinant mouse RyR2 triple phosphomimetic mutant S2807D/S2813D/S2030D in complex with FKBP12.6 and nanodisc under closed-state conditions
Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION
Authors:Iyer, K.A, Hu, Y, Murayama, T, Samso, M.
Deposit date:2022-07-26
Release date:2024-01-31
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Recombinant mouse RyR2 triple phosphomimetic mutant S2807D/S2813D/S2030D in complex with FKBP12.6 and nanodisc under closed-state conditions
To Be Published

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數據於2024-07-17公開中

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