1QF5

DESIGN, SYNTHESIS, AND X-RAY CRYSTAL STRUCTURE OF AN ENZYME BOUND BISUBSTRATE HYBRID INHIBITOR OF ADENYLOSUCCINATE SYNTHETASE

Summary for 1QF5
Related1QF4
DescriptorPROTEIN (ADENYLOSUCCINATE SYNTHETASE), PHOSPHATE ION, MAGNESIUM ION, ... (6 entities in total)
Functional Keywordspurine biosynthesis, synthetase, gtp-binding, gtp-hydrolysing enzymes, ligase
Biological sourceEscherichia coli
Total number of polymer chains1
Total formula weight48291.38
Authors
Hanessian, S.,Lu, P.-P.,Sanceau, J.-Y.,Chemla, P.,Prade, L.,Gohda, K.,Cowan-Jacob, S.W.,Fonne-Pfister, R. (deposition date: 1999-04-06, release date: 1999-12-02, Last modification date: 2019-11-20)
Primary citationChemla, P.,Cowan-Jacob, S.W.,Fonne-Pfister, R.,Gohda, K.,Hanessian, S.,Lu, P.P.,Prade, L.,Sanceau, J.Y.
An enzyme-bound bisubstrate hybrid inhibitor of adenylosuccinate synthetase
Angew.Chem.Int.Ed.Engl., 38:3159-3162, 1999
PubMed: 10556888
DOI: 110.1002/(SICI)1521-3773(19991102)38:21<3159::AID-ANIE3159>3.0.CO;2-2
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation
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178938

PDB entries from 2021-06-16