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1TMT
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BU of 1tmt by Molmil
CHANGES IN INTERACTIONS IN COMPLEXES OF HIRUDIN DERIVATIVES AND HUMAN ALPHA-THROMBIN DUE TO DIFFERENT CRYSTAL FORMS
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), ...
Authors:Priestle, J.P, Gruetter, M.G.
Deposit date:1994-05-26
Release date:1994-09-30
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Changes in interactions in complexes of hirudin derivatives and human alpha-thrombin due to different crystal forms.
Protein Sci., 2, 1993
4MOA
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BU of 4moa by Molmil
Crystal structure of CRY4BA-R203Q TOXIN
Descriptor: Pesticidal crystal protein cry4Ba
Authors:Thamwiriyasati, N, Angsuthanasombat, C, Chen, C.-J.
Deposit date:2013-09-11
Release date:2014-12-10
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Potential Prepore Trimer Formation by the Bacillus thuringiensis Mosquito-specific Toxin: MOLECULAR INSIGHTS INTO A CRITICAL PREREQUISITE OF MEMBRANE-BOUND MONOMERS
J.Biol.Chem., 290, 2015
8SRZ
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BU of 8srz by Molmil
Structure of a bacterial death-like domain from Lysobacter enzymogenes
Descriptor: Probable serine protease FE772_23065
Authors:Johnson, A.G, Kranzusch, P.J.
Deposit date:2023-05-08
Release date:2023-06-07
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:CARD-like domains mediate anti-phage defense in bacterial gasdermin systems.
Biorxiv, 2023
6EE5
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BU of 6ee5 by Molmil
Reactive centre loop dynamics and serpin specificity
Descriptor: Conserpin-AATRCL
Authors:Marijanovic, E.M, Porebski, B.T, McGowan, S, Buckle, A.M.
Deposit date:2018-08-13
Release date:2018-08-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Reactive centre loop dynamics and serpin specificity.
Sci Rep, 9, 2019
1LQX
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BU of 1lqx by Molmil
Crystal structure of V45E mutant of cytochrome b5
Descriptor: PROTOPORPHYRIN IX CONTAINING FE, cytochrome b5
Authors:Gan, J.-H, Wu, J, Wang, Z.-Q, Wang, Y.-H, Huang, Z.-X, Xia, Z.-X.
Deposit date:2002-05-14
Release date:2002-09-04
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of V45E and V45Y mutants and structure comparison of a variety of cytochrome b5 mutants.
Acta Crystallogr.,Sect.D, 58, 2002
1LR6
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BU of 1lr6 by Molmil
Crystal structure of V45Y mutant of cytochrome b5
Descriptor: PROTOPORPHYRIN IX CONTAINING FE, cytochrome b5
Authors:Gan, J.-H, Wu, J, Wang, Z.-Q, Wang, Y.-H, Huang, Z.-X, Xia, Z.-X.
Deposit date:2002-05-15
Release date:2002-09-04
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of V45E and V45Y mutants and structure comparison of a variety of cytochrome b5 mutants.
Acta Crystallogr.,Sect.D, 58, 2002
1BCU
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BU of 1bcu by Molmil
ALPHA-THROMBIN COMPLEXED WITH HIRUGEN AND PROFLAVIN
Descriptor: ALPHA-THROMBIN, HIRUGEN, PROFLAVIN
Authors:Conti, E, Rivetti, C, Wonacott, A, Brick, P.
Deposit date:1998-05-02
Release date:1998-10-14
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray and spectrophotometric studies of the binding of proflavin to the S1 specificity pocket of human alpha-thrombin.
FEBS Lett., 425, 1998
1E0F
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BU of 1e0f by Molmil
Crystal structure of the human alpha-thrombin-haemadin complex: an exosite II-binding inhibitor
Descriptor: HAEMADIN, THROMBIN
Authors:Richardson, J.L, Kroeger, B, Hoefken, W, Pereira, P, Huber, R, Bode, W, Fuentes-Prior, P.
Deposit date:2000-03-27
Release date:2000-11-03
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal Structure of the Human Alpha-Thrombin-Haemadin Complex: An Exosite II-Binding Inhibitor
Embo J., 19, 2000
1DIT
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BU of 1dit by Molmil
COMPLEX OF A DIVALENT INHIBITOR WITH THROMBIN
Descriptor: ALPHA-THROMBIN, PEPTIDE INHIBITOR CVS995
Authors:Tulinsky, A, Krishnan, R.
Deposit date:1995-07-20
Release date:1996-06-10
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Synthesis, structure, and structure-activity relationships of divalent thrombin inhibitors containing an alpha-keto-amide transition-state mimetic.
Protein Sci., 5, 1996
2AIP
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BU of 2aip by Molmil
Crystal structure of native protein C activator from the venom of copperhead snake Agkistrodon contortrix contortrix
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, GLYCEROL, ...
Authors:Murakami, M.T, Arni, R.K.
Deposit date:2005-07-30
Release date:2005-09-06
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Thrombomodulin-independent Activation of Protein C and Specificity of Hemostatically Active Snake Venom Serine Proteinases: CRYSTAL STRUCTURES OF NATIVE AND INHIBITED AGKISTRODON CONTORTRIX CONTORTRIX PROTEIN C ACTIVATOR.
J.Biol.Chem., 280, 2005
6AOD
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BU of 6aod by Molmil
FXIa antibody complex
Descriptor: COBALT (II) ION, Coagulation factor XI, FXIa Antibody FAB Heavy Chain, ...
Authors:Lolicato, M, Minor, D.L.
Deposit date:2017-08-15
Release date:2018-03-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis for Activity and Specificity of an Anticoagulant Anti-FXIa Monoclonal Antibody and a Reversal Agent.
Structure, 26, 2018
6CS2
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BU of 6cs2 by Molmil
SARS Spike Glycoprotein - human ACE2 complex, Stabilized variant, all ACE2-bound particles
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
Authors:Kirchdoerfer, R.N, Wang, N, Pallesen, J, Turner, H.L, Cottrell, C.A, McLellan, J.S, Ward, A.B.
Deposit date:2018-03-19
Release date:2018-04-11
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
6CRV
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BU of 6crv by Molmil
SARS Spike Glycoprotein, Stabilized variant, C3 symmetry
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin, ...
Authors:Kirchdoerfer, R.N, Wang, N, Pallesen, J, Turner, H.L, Cottrell, C.A, McLellan, J.S, Ward, A.B.
Deposit date:2018-03-19
Release date:2018-04-11
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
3B9F
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BU of 3b9f by Molmil
1.6 A structure of the PCI-thrombin-heparin complex
Descriptor: 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, GLYCEROL, Plasma serine protease inhibitor, ...
Authors:Li, W, Adams, T.E, Huntington, J.A.
Deposit date:2007-11-05
Release date:2008-04-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Molecular basis of thrombin recognition by protein C inhibitor revealed by the 1.6-A structure of the heparin-bridged complex.
Proc.Natl.Acad.Sci.Usa, 105, 2008
6CRX
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BU of 6crx by Molmil
SARS Spike Glycoprotein, Stabilized variant, two S1 CTDs in the upwards conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin, ...
Authors:Kirchdoerfer, R.N, Wang, N, Pallesen, J, Turner, H.L, Cottrell, C.A, McLellan, J.S, Ward, A.B.
Deposit date:2018-03-19
Release date:2018-04-11
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
6CRW
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BU of 6crw by Molmil
SARS Spike Glycoprotein, Stabilized variant, single upwards S1 CTD conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin, ...
Authors:Kirchdoerfer, R.N, Wang, N, Pallesen, J, Turner, H.L, Cottrell, C.A, McLellan, J.S, Ward, A.B.
Deposit date:2018-03-19
Release date:2018-04-11
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
4E1P
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BU of 4e1p by Molmil
Crystal structure of the dimerization domain of Lsr2 from Mycobacterium tuberculosis in the P 1 21 1 space group
Descriptor: Protein lsr2
Authors:Summers, E.L, Meindl, K, Uson, I, Arcus, V.L.
Deposit date:2012-03-06
Release date:2012-06-20
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.728 Å)
Cite:The structure of the oligomerization domain of Lsr2 from Mycobacterium tuberculosis reveals a mechanism for chromosome organization and protection.
Plos One, 7, 2012
4OQO
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BU of 4oqo by Molmil
Crystal structure of the tryptic generated iron-free C-lobe of bovine Lactoferrin at 2.42 Angstrom resolution
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lactotransferrin
Authors:Singh, A, Rastogi, N, Pandey, S, Bhushan, A, Sinha, M, Kaur, P, Sharma, S, Singh, T.P.
Deposit date:2014-02-10
Release date:2014-03-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structure of the iron-free true C-terminal half of bovine lactoferrin produced by tryptic digestion and its functional significance in the gut.
Febs J., 281, 2014
1GBK
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BU of 1gbk by Molmil
ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-ALANINE BORONIC ACID
Descriptor: ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-ALANINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:Mace, J.E, Agard, D.A.
Deposit date:1995-09-06
Release date:1996-01-29
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity.
J.Mol.Biol., 254, 1995
1GBF
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BU of 1gbf by Molmil
ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA AND GLY 216 REPLACED BY LEU COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-ALANINE BORONIC ACID
Descriptor: ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-ALANINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:Mace, J.E, Agard, D.A.
Deposit date:1995-09-06
Release date:1996-01-29
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity.
J.Mol.Biol., 254, 1995
1GBD
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BU of 1gbd by Molmil
ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA AND GLY 216 REPLACED BY ALA COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-PHENYLALANINE BORONIC ACID
Descriptor: ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-PHENYLALANINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:Mace, J.E, Agard, D.A.
Deposit date:1995-09-06
Release date:1996-01-29
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity.
J.Mol.Biol., 254, 1995
1GBM
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BU of 1gbm by Molmil
ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-PHENYLALANINE BORONIC ACID
Descriptor: ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-PHENYLALANINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:Mace, J.E, Agard, D.A.
Deposit date:1995-09-06
Release date:1996-01-29
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity.
J.Mol.Biol., 254, 1995
1GBI
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BU of 1gbi by Molmil
ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA AND GLY 216 REPLACED BY LEU COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-PHENYLALANINE BORONIC ACID
Descriptor: ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-PHENYLALANINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:Mace, J.E, Agard, D.A.
Deposit date:1995-09-06
Release date:1996-01-29
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity.
J.Mol.Biol., 254, 1995
1GBL
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BU of 1gbl by Molmil
ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-LEUCINE BORONIC ACID
Descriptor: ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-LEUCINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:Mace, J.E, Agard, D.A.
Deposit date:1995-09-06
Release date:1996-01-29
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity.
J.Mol.Biol., 254, 1995
1GBC
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BU of 1gbc by Molmil
ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA AND GLY 216 REPLACED BY ALA COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-LEUCINE BORONIC ACID
Descriptor: ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-LEUCINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:Mace, J.E, Agard, D.A.
Deposit date:1995-09-06
Release date:1996-01-29
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity.
J.Mol.Biol., 254, 1995

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數據於2024-08-28公開中

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