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8P9L
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Crystal structure of the first bromodomain of human BRD4 in complex with the dual BET/HDAC inhibitor NB512
Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, ~{N}-(2-azanyl-5-phenyl-phenyl)-5-(6-methyl-7-oxidanylidene-1~{H}-pyrrolo[2,3-c]pyridin-4-yl)pyridine-2-carboxamide
Authors:Balourdas, D.I, Bauer, N, Knapp, S, Joerger, A.C, Structural Genomics Consortium (SGC)
Deposit date:2023-06-06
Release date:2023-07-05
Last modified:2024-06-26
Method:X-RAY DIFFRACTION (1.29 Å)
Cite:Development of Potent Dual BET/HDAC Inhibitors via Pharmacophore Merging and Structure-Guided Optimization.
Acs Chem.Biol., 19, 2024
8P9J
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BU of 8p9j by Molmil
Crystal structure of the first bromodomain of human BRD4 in complex with the dual BET/HDAC inhibitor NB500
Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, ~{N}-(2-aminophenyl)-5-(6-methyl-7-oxidanylidene-1~{H}-pyrrolo[2,3-c]pyridin-4-yl)pyridine-2-carboxamide
Authors:Balourdas, D.I, Bauer, N, Knapp, S, Joerger, A.C, Structural Genomics Consortium (SGC)
Deposit date:2023-06-06
Release date:2023-07-05
Last modified:2024-06-26
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Development of Potent Dual BET/HDAC Inhibitors via Pharmacophore Merging and Structure-Guided Optimization.
Acs Chem.Biol., 19, 2024
2GSM
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BU of 2gsm by Molmil
Catalytic Core (Subunits I and II) of Cytochrome c oxidase from Rhodobacter sphaeroides
Descriptor: CADMIUM ION, CALCIUM ION, COPPER (II) ION, ...
Authors:Qin, L, Hiser, C, Mulichak, A, Garavito, R.M, Ferguson-Miller, S.
Deposit date:2006-04-26
Release date:2006-10-10
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Identification of conserved lipid/detergent-binding sites in a high-resolution structure of the membrane protein cytochrome c oxidase.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2XZJ
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THE ASPERGILLUS FUMIGATUS SIALIDASE IS A KDNASE: STRUCTURAL AND MECHANISTIC INSIGHTS
Descriptor: 2,6-anhydro-3-deoxy-D-glycero-D-galacto-non-2-enonic acid, EXTRACELLULAR SIALIDASE/NEURAMINIDASE, PUTATIVE, ...
Authors:Telford, J.C, Yeung, J.H.F, Kiefel, M.J, Watts, A.G, Hader, S, Chan, J, Bennet, A.J, Moore, M.M, Taylor, G.L.
Deposit date:2010-11-26
Release date:2011-01-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:The Aspergillus Fumigatus Sialidase is a Kdnase: Structural and Mechanistic Insights.
J.Biol.Chem., 286, 2011
2XZI
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THE ASPERGILLUS FUMIGATUS SIALIDASE IS A KDNASE: STRUCTURAL AND MECHANISTIC INSIGHTS
Descriptor: EXTRACELLULAR SIALIDASE/NEURAMINIDASE, PUTATIVE, GLYCEROL, ...
Authors:Telford, J.C, Yeung, J.H.F, Kiefel, M.J, Watts, A.G, Hader, S, Chan, J, Bennet, A.J, Moore, M.M, Taylor, G.L.
Deposit date:2010-11-26
Release date:2011-01-19
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:The Aspergillus Fumigatus Sialidase is a Kdnase: Structural and Mechanistic Insights.
J.Biol.Chem., 286, 2011
2XZK
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BU of 2xzk by Molmil
THE ASPERGILLUS FUMIGATUS SIALIDASE IS A KDNASE: STRUCTURAL AND MECHANISTIC INSIGHTS
Descriptor: (2R,3R,4R,5R,6S)-2,3-bis(fluoranyl)-4,5-bis(oxidanyl)-6-[(1R,2R)-1,2,3-tris(oxidanyl)propyl]oxane-2-carboxylic acid, 3-deoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid, CHLORIDE ION, ...
Authors:Telford, J.C, Yeung, J.H.F, Kiefel, M.J, Watts, A.G, Hader, S, Chan, J, Bennet, A.J, Moore, M.M, Taylor, G.L.
Deposit date:2010-11-26
Release date:2011-01-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The Aspergillus Fumigatus Sialidase is a Kdnase: Structural and Mechanistic Insights.
J.Biol.Chem., 286, 2011
2Z8G
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BU of 2z8g by Molmil
Aspergillus niger ATCC9642 isopullulanase complexed with isopanose
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Isopullulanase, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-6)-beta-D-glucopyranose
Authors:Mizuno, M, Koide, A, Yamamura, A, Akeboshi, H, Yoshida, H, Kamitori, S, Sakano, Y, Nishikawa, A, Tonozuka, T.
Deposit date:2007-09-05
Release date:2007-12-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of Aspergillus niger Isopullulanase, a Member of Glycoside Hydrolase Family 49
J.Mol.Biol., 376, 2008
5LWW
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BU of 5lww by Molmil
Crystal structure of a laccase-like multicopper oxidase McoG from Aspergillus niger bound to zinc
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ...
Authors:Ferraroni, M, Briganti, F, Tamayo-Ramos, J.A, van Berkel, W.J.H, Westphal, A.H.
Deposit date:2016-09-19
Release date:2017-05-03
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure and function of Aspergillus niger laccase McoG
Biocatalysis, 2017
7N0U
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Complex of recombinant Bet v 1 with Fab fragment of REGN5713
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, REGN5713 Fab fragment heavy chain, REGN5713 Fab fragment light chain, ...
Authors:Franklin, M.C, Romero Hernandez, A.
Deposit date:2021-05-26
Release date:2021-08-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:Targeting immunodominant Bet v 1 epitopes with monoclonal antibodies prevents the birch allergic response.
J.Allergy Clin.Immunol., 149, 2022
5LWX
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BU of 5lwx by Molmil
Crystal structure of the H253D mutant of McoG from Aspergillus niger
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, ...
Authors:Ferraroni, M, Briganti, F, Tamayo-Ramos, J.A, van Berkel, W.J.H, Westphal, A.H.
Deposit date:2016-09-19
Release date:2017-05-03
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Structure and function of Aspergillus niger laccase McoG
Biocatalysis, 2017
5LM8
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Crystal structure of a laccase-like multicopper oxidase McoG from from Aspergillus niger
Descriptor: 'Multicopper oxidase, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Ferraroni, M, Briganti, F, Tamayo-Ramos, J.A, van Berkel, W.J.H, Westphal, A.H.
Deposit date:2016-07-29
Release date:2017-05-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure and function of Aspergillus niger laccase McoG
Biocatalysis, 2017
2XCY
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BU of 2xcy by Molmil
Crystal structure of Aspergillus fumigatus sialidase
Descriptor: CHLORIDE ION, EXTRACELLULAR SIALIDASE/NEURAMINIDASE, PUTATIVE, ...
Authors:Telford, J.C, Yeung, J, Xu, G, Bennet, A, Moore, M.M, Taylor, G.L.
Deposit date:2010-04-27
Release date:2010-05-12
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:The Aspergillus Fumigatus Sialidase is a Kdnase: Structural and Mechanistic Insights.
J.Biol.Chem., 286, 2011
1ZEO
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BU of 1zeo by Molmil
Crystal Structure of Human PPAR-gamma Ligand Binding Domain Complexed with an Alpha-Aryloxyphenylacetic Acid Agonist
Descriptor: (2S)-(4-ISOPROPYLPHENYL)[(2-METHYL-3-OXO-5,7-DIPROPYL-2,3-DIHYDRO-1,2-BENZISOXAZOL-6-YL)OXY]ACETATE, Peroxisome proliferator activated receptor gamma
Authors:Shi, G.Q, Dropinski, J.F, McKeever, B.M, Adams, A.D, MacNaul, K.L, Elbrecht, A, Berger, J.P, Zhou, G, Doebber, T.W.
Deposit date:2005-04-19
Release date:2006-04-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Design and Synthesis of alpha-Aryloxyphenylacetic Acid Derivatives: A Novel Class of PPAR alpha/gamma Dual Agonists with Potent Antihyperglycemic and Lipid Modulating Activity
J.Med.Chem., 48, 2005
5XH8
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BU of 5xh8 by Molmil
Aspergillus kawachii beta-fructofuranosidase complexed with glycerol
Descriptor: ACETATE ION, Extracellular invertase, GLYCEROL, ...
Authors:Nagaya, M, Tonozuka, T.
Deposit date:2017-04-19
Release date:2017-07-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of a beta-fructofuranosidase with high transfructosylation activity from Aspergillus kawachii
Biosci. Biotechnol. Biochem., 81, 2017
5XH9
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BU of 5xh9 by Molmil
Aspergillus kawachii beta-fructofuranosidase
Descriptor: Extracellular invertase, SODIUM ION
Authors:Nagaya, M, Tonozuka, T.
Deposit date:2017-04-19
Release date:2017-07-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of a beta-fructofuranosidase with high transfructosylation activity from Aspergillus kawachii
Biosci. Biotechnol. Biochem., 81, 2017
5XHA
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BU of 5xha by Molmil
Aspergillus kawachii beta-fructofuranosidase complexed with fructose
Descriptor: Extracellular invertase, SODIUM ION, beta-D-fructofuranose, ...
Authors:Nagaya, M, Tonozuka, T.
Deposit date:2017-04-19
Release date:2017-07-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of a beta-fructofuranosidase with high transfructosylation activity from Aspergillus kawachii
Biosci. Biotechnol. Biochem., 81, 2017
5J91
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BU of 5j91 by Molmil
Structure of the Wild-type 70S E coli ribosome bound to Tigecycline
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ...
Authors:Cocozaki, A, Ferguson, A.
Deposit date:2016-04-08
Release date:2016-07-06
Last modified:2016-08-03
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors.
Proc.Natl.Acad.Sci.USA, 113, 2016
5J5B
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BU of 5j5b by Molmil
Structure of the WT E coli ribosome bound to tetracycline
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ...
Authors:Cocozaki, A, Ferguson, A.
Deposit date:2016-04-01
Release date:2016-07-27
Last modified:2018-08-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors.
Proc.Natl.Acad.Sci.USA, 113, 2016
5J8A
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BU of 5j8a by Molmil
Structure of the E coli 70S ribosome with the U1052G mutation in 16S rRNA bound to tigecycline
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ...
Authors:Cocozaki, A, Ferguson, A.
Deposit date:2016-04-07
Release date:2016-07-06
Last modified:2016-08-03
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors.
Proc.Natl.Acad.Sci.USA, 113, 2016
5JC9
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BU of 5jc9 by Molmil
Structure of the Escherichia coli ribosome with the U1052G mutation in the 16S rRNA
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ...
Authors:Cocozaki, A, Ferguson, A.
Deposit date:2016-04-14
Release date:2016-07-06
Last modified:2016-08-03
Method:X-RAY DIFFRACTION (3.03 Å)
Cite:Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors.
Proc.Natl.Acad.Sci.USA, 113, 2016
8A53
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BU of 8a53 by Molmil
Crystal structure of AtMCA-IIf C147A (metacaspase 9) from Arabidopsis thaliana
Descriptor: Metacaspase-9, NITRATE ION
Authors:Sabljic, I, Stael, S, Stahlberg, J, Bozhkov, P.
Deposit date:2022-06-14
Release date:2023-05-31
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure-function study of a Ca 2+ -independent metacaspase involved in lateral root emergence.
Proc.Natl.Acad.Sci.USA, 120, 2023
1KUL
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BU of 1kul by Molmil
GLUCOAMYLASE, GRANULAR STARCH-BINDING DOMAIN, NMR, 5 STRUCTURES
Descriptor: GLUCOAMYLASE
Authors:Sorimachi, K, Jacks, A.J, Le Gal-Coeffet, M.-F, Williamson, G, Archer, D.B, Williamson, M.P.
Deposit date:1996-01-12
Release date:1996-07-11
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of the granular starch binding domain of glucoamylase from Aspergillus niger by nuclear magnetic resonance spectroscopy.
J.Mol.Biol., 259, 1996
1KUM
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BU of 1kum by Molmil
GLUCOAMYLASE, GRANULAR STARCH-BINDING DOMAIN, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: GLUCOAMYLASE
Authors:Sorimachi, K, Jacks, A.J, Le Gal-Coeffet, M.-F, Williamson, G, Archer, D.B, Williamson, M.P.
Deposit date:1996-01-12
Release date:1996-07-11
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of the granular starch binding domain of glucoamylase from Aspergillus niger by nuclear magnetic resonance spectroscopy.
J.Mol.Biol., 259, 1996
5IT8
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BU of 5it8 by Molmil
High-resolution structure of the Escherichia coli ribosome
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ...
Authors:Cocozaki, A, Ferguson, A.
Deposit date:2016-03-16
Release date:2016-07-27
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.12 Å)
Cite:Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors.
Proc.Natl.Acad.Sci.USA, 113, 2016
5J7L
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BU of 5j7l by Molmil
Structure of the 70S E coli ribosome with the U1052G mutation in the 16S rRNA bound to tetracycline
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ...
Authors:Cocozaki, A, Ferguson, A.
Deposit date:2016-04-06
Release date:2016-07-27
Last modified:2018-08-15
Method:X-RAY DIFFRACTION (3 Å)
Cite:Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors.
Proc.Natl.Acad.Sci.USA, 113, 2016

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數據於2024-07-31公開中

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