7BMS
| HEWL in cesium chloride (1.5 M CsCl in crystallization condition and cryo protectant) | Descriptor: | 1,2-ETHANEDIOL, CESIUM ION, CHLORIDE ION, ... | Authors: | Koelmel, W, Kuper, J, Kisker, C. | Deposit date: | 2021-01-20 | Release date: | 2021-10-06 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Cesium based phasing of macromolecules: a general easy to use approach for solving the phase problem. Sci Rep, 11, 2021
|
|
4U80
| MEK 1 kinase bound to G799 | Descriptor: | 3-[(4-cyclopropyl-2-fluorophenyl)amino]-N-(2-hydroxyethoxy)furo[3,2-c]pyridine-2-carboxamide, Dual specificity mitogen-activated protein kinase kinase 1, MAGNESIUM ION, ... | Authors: | Ultsch, M.H, Robarge, K.D, Weismann, C. | Deposit date: | 2014-07-31 | Release date: | 2014-09-24 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure based design of novel 6,5 heterobicyclic mitogen-activated protein kinase kinase (MEK) inhibitors leading to the discovery of imidazo[1,5-a] pyrazine G-479. Bioorg.Med.Chem.Lett., 24, 2014
|
|
5H8T
| Crystal structure of human cellular retinol binding protein 1 in complex with all-trans-retinol | Descriptor: | RETINOL, Retinol-binding protein 1 | Authors: | Golczak, M, Arne, J.M, Silvaroli, J.A, Kiser, P.D, Banerjee, S. | Deposit date: | 2015-12-23 | Release date: | 2016-03-02 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.21 Å) | Cite: | Ligand Binding Induces Conformational Changes in Human Cellular Retinol-binding Protein 1 (CRBP1) Revealed by Atomic Resolution Crystal Structures. J.Biol.Chem., 291, 2016
|
|
7BMO
| HEWL in cesium chloride (0.25 M CsCl in protein buffer) | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Hen egg white lysozyme, ... | Authors: | Koelmel, W, Kuper, J, Kisker, C. | Deposit date: | 2021-01-20 | Release date: | 2021-10-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Cesium based phasing of macromolecules: a general easy to use approach for solving the phase problem. Sci Rep, 11, 2021
|
|
5HZ5
| |
7BMP
| HEWL in cesium chloride (0.25 M CsCl in protein buffer and cryo protectant). | Descriptor: | 1,2-ETHANEDIOL, CESIUM ION, CHLORIDE ION, ... | Authors: | Koelmel, W, Kuper, J, Kisker, C. | Deposit date: | 2021-01-20 | Release date: | 2021-10-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Cesium based phasing of macromolecules: a general easy to use approach for solving the phase problem. Sci Rep, 11, 2021
|
|
4TWS
| Gadolinium Derivative of Tetragonal Hen Egg-White Lysozyme at 1.45 A Resolution | Descriptor: | 10-((2R)-2-HYDROXYPROPYL)-1,4,7,10-TETRAAZACYCLODODECANE 1,4,7-TRIACETIC ACID, CHLORIDE ION, GADOLINIUM ATOM, ... | Authors: | Holton, J.M, Classen, S, Frankel, K.A, Tainer, J.A. | Deposit date: | 2014-07-01 | Release date: | 2014-08-20 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | The R-factor gap in macromolecular crystallography: an untapped potential for insights on accurate structures. Febs J., 281, 2014
|
|
7BMR
| HEWL in cesium chloride (0.25 M CsCl in protein buffer and 1.71 M CsCl in cryo protectant) | Descriptor: | 1,2-ETHANEDIOL, CESIUM ION, CHLORIDE ION, ... | Authors: | Koelmel, W, Kuper, J, Kisker, C. | Deposit date: | 2021-01-20 | Release date: | 2021-10-06 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Cesium based phasing of macromolecules: a general easy to use approach for solving the phase problem. Sci Rep, 11, 2021
|
|
7BMQ
| HEWL in cesium chloride (1.71 M CsCl in cryo protectant) | Descriptor: | 1,2-ETHANEDIOL, CESIUM ION, CHLORIDE ION, ... | Authors: | Koelmel, W, Kuper, J, Kisker, C. | Deposit date: | 2021-01-20 | Release date: | 2021-10-06 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Cesium based phasing of macromolecules: a general easy to use approach for solving the phase problem. Sci Rep, 11, 2021
|
|
6VZH
| Structure of Human Vaccinia-related Kinase 1 (VRK1) Bound to LDSM311 | Descriptor: | (7~{R})-2-[[3,5-bis(fluoranyl)-4-oxidanyl-phenyl]amino]-5,7-dimethyl-8-prop-2-ynyl-7~{H}-pteridin-6-one, 1,2-ETHANEDIOL, SULFATE ION, ... | Authors: | dos Reis, C.V, Dutra, L.A, Gama, F, Ferreira, M, Mascarello, A, Azevedo, H, Guimaraes, C, Massirer, K.B, Arruda, P, Edwards, A.M, Counago, R.M, Structural Genomics Consortium (SGC) | Deposit date: | 2020-02-28 | Release date: | 2020-03-11 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Structure of Human Vaccinia-related Kinase 1 (VRK1) Bound to LDSM311 To be Published
|
|
7BMT
| HEWL in sodium chloride | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Lysozyme, ... | Authors: | Koelmel, W, Kuper, J, Kisker, C. | Deposit date: | 2021-01-20 | Release date: | 2021-10-06 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Cesium based phasing of macromolecules: a general easy to use approach for solving the phase problem. Sci Rep, 11, 2021
|
|
5H8E
| Crystal structure of CK2 with compound 7h | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Casein kinase II subunit alpha, ... | Authors: | Ferguson, A.D. | Deposit date: | 2015-12-23 | Release date: | 2016-02-10 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Potent and Selective CK2 Kinase Inhibitors with Effects on Wnt Pathway Signaling in Vivo. Acs Med.Chem.Lett., 7, 2016
|
|
7BB1
| Lysozyme crystallized in the presence of the hydrated deep eutectic solvent Choline chloride-Glutamic acid 2:1 | Descriptor: | ACETATE ION, CHLORIDE ION, CHOLINE ION, ... | Authors: | Belviso, B.D, Caliandro, R, Carrozzini, B. | Deposit date: | 2020-12-16 | Release date: | 2021-10-20 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Introducing Protein Crystallization in Hydrated Deep Eutectic Solvents Acs Sustain Chem Eng, 9, 2021
|
|
4UDF
| STRUCTURAL BASIS OF HUMAN PARECHOVIRUS NEUTRALIZATION BY HUMAN MONOCLONAL ANTIBODIES | Descriptor: | HUMAN MONOCLONAL ANTIBODY, Protein VP0, Protein VP3 | Authors: | Shakeel, S, Westerhuis, B.M, Ora, A, Koen, G, Bakker, A.Q, Claassen, Y, Beaumont, T, Wolthers, K.C, Butcher, S.J. | Deposit date: | 2014-12-10 | Release date: | 2015-07-22 | Last modified: | 2018-10-03 | Method: | ELECTRON MICROSCOPY (20 Å) | Cite: | Structural Basis of Human Parechovirus Neutralization by Human Monoclonal Antibodies. J. Virol., 89, 2015
|
|
7B9J
| Lysozyme crystallized in the presence of the hydrated deep eutectic solvent Choline chloride-Urea 1:2 | Descriptor: | ACETATE ION, CHLORIDE ION, CHOLINE ION, ... | Authors: | Belviso, B.D, Caliandro, R, Carrozzini, B. | Deposit date: | 2020-12-14 | Release date: | 2021-10-20 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Introducing Protein Crystallization in Hydrated Deep Eutectic Solvents Acs Sustain Chem Eng, 9, 2021
|
|
7BAZ
| Lysozyme crystallized in the presence of the hydrated deep eutectic solvent Choline chloride-Glycerol 1:2 | Descriptor: | ACETATE ION, CHLORIDE ION, CHOLINE ION, ... | Authors: | Belviso, B.D, Caliandro, R, Carrozzini, B. | Deposit date: | 2020-12-16 | Release date: | 2021-10-20 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Introducing Protein Crystallization in Hydrated Deep Eutectic Solvents Acs Sustain Chem Eng, 9, 2021
|
|
6W5B
| |
7BBT
| Structure of cytochrome c in complex with a p-benzyl-sulfonato-calix[8]arene-PEG pseudorotaxane | Descriptor: | 4-[[49,50,51,52,53,54,55,56-octahydroxy-11,17,23,29,35,41,47-heptakis[(4-sulfonatophenyl)methyl]-5-nonacyclo[43.3.1.13,7.19,13.115,19.121,25.127,31.133,37.139,43]hexapentaconta-1(49),3,5,7(56),9,11,13(55),15,17,19(54),21,23,25(53),27,29,31(52),33,35,37(51),39,41,43(50),45,47-tetracosaenyl]methyl]benzenesulfonate, Cytochrome c iso-1, HEME C, ... | Authors: | Mockler, N.M, Ramberg, K, Guagnini, F, Raston, C.L, Crowley, P.B. | Deposit date: | 2020-12-18 | Release date: | 2021-10-20 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.023 Å) | Cite: | Noncovalent Protein-Pseudorotaxane Assembly Incorporating an Extended Arm Calix[8]arene with alpha-Helical Recognition Properties. Cryst.Growth Des., 21, 2021
|
|
5HD4
| Dissecting Therapeutic Resistance to ERK Inhibition Rat Wild Type SCH772984 in complex with (3R)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-N-[3-(pyridin-4-yl)-2H-indazol-5-yl]pyrrolidine-3-carboxamide | Descriptor: | (3R)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-N-[3-(pyridin-4-yl)-2H-indazol-5-yl]pyrrolidine-3-carboxamide, DIMETHYL SULFOXIDE, Mitogen-activated protein kinase 1, ... | Authors: | Jha, S, Morris, E.J, Hruza, A, Mansueto, M.S, Schroeder, G, Arbanas, J, McMasters, D, Restaino, C.R, Dayananth, R, Black, S, Elsen, N.L, Mannarino, A, Cooper, A, Fawell, S, Zawel, L, Jayaraman, L, Samatar, A.A. | Deposit date: | 2016-01-04 | Release date: | 2016-02-24 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Dissecting Therapeutic Resistance to ERK Inhibition. Mol.Cancer Ther., 15, 2016
|
|
6WP0
| |
5HDI
| Structural characterization of CYP144A1, a Mycobacterium tuberculosis cytochrome P450 | Descriptor: | Cytochrome P450 144, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Chenge, J, Driscoll, M.D, McLean, K.J, Munro, A.W, Leys, D. | Deposit date: | 2016-01-05 | Release date: | 2016-05-04 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Structural characterization of CYP144A1 - a cytochrome P450 enzyme expressed from alternative transcripts in Mycobacterium tuberculosis. Sci Rep, 6, 2016
|
|
6WMI
| ZNF410 zinc fingers 1-5 with 17 mer blunt DNA Oligonucleotide | Descriptor: | 1,2-ETHANEDIOL, DNA (5'-D(*CP*AP*CP*AP*TP*CP*CP*CP*AP*TP*AP*AP*TP*AP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*TP*AP*TP*GP*GP*GP*AP*TP*GP*TP*G)-3'), ... | Authors: | Ren, R, Horton, J.R, Cheng, X. | Deposit date: | 2020-04-21 | Release date: | 2020-12-09 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | ZNF410 Uniquely Activates the NuRD Component CHD4 to Silence Fetal Hemoglobin Expression. Mol.Cell, 81, 2021
|
|
7KYZ
| |
5HE5
| |
6WRL
| The interaction of chlorido(1,5-cyclooctadiene)([4-(2-((tert-butoxycarbonyl)amino)-3-methoxy-3-oxopropyl)-1,3-dimethyl-1H-imidazol-3-ide])rhodium(I) with HEWL after 1 week | Descriptor: | ACETATE ION, Lysozyme, Rhodium, ... | Authors: | Sullivan, M.P, John, M, Hartinger, C.G, Goldstone, D.C. | Deposit date: | 2020-04-29 | Release date: | 2020-12-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | A Combined Spectroscopic and Protein Crystallography Study Reveals Protein Interactions of Rh I (NHC) Complexes at the Molecular Level. Inorg.Chem., 59, 2020
|
|