5KUE
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![BU of 5kue by Molmil](/molmil-images/mine/5kue) | Human SeMet incorporated I141M/L146M mitochondrial calcium uniporter (residues 72-189) crystal structure with magnesium | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Calcium uniporter protein, ... | Authors: | Mok, C.Y.M, Lee, S.K, Junop, M.S, Stathopulos, P.B. | Deposit date: | 2016-07-13 | Release date: | 2016-09-07 | Last modified: | 2020-01-08 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural Insights into Mitochondrial Calcium Uniporter Regulation by Divalent Cations. Cell Chem Biol, 23, 2016
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4XTB
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![BU of 4xtb by Molmil](/molmil-images/mine/4xtb) | Crystal structure of the N-terminal domain of the human mitochondrial calcium uniporter | Descriptor: | Calcium uniporter protein, mitochondrial, TETRAETHYLENE GLYCOL | Authors: | Lee, Y, Min, C.K, Kim, T.G, Song, H.K, Lim, Y, Kim, D, Shin, K, Kang, M, Kang, J.Y, Youn, H.-S, Lee, J.-G, An, J.Y, Park, K.R, Lim, J.J, Kim, J.H, Kim, J.H, Park, Z.Y, Kim, Y.-S, Wang, J, Kim, D.H, Eom, S.H. | Deposit date: | 2015-01-23 | Release date: | 2015-09-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure and function of the N-terminal domain of the human mitochondrial calcium uniporter. Embo Rep., 16, 2015
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5KUJ
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![BU of 5kuj by Molmil](/molmil-images/mine/5kuj) | Human mitochondrial calcium uniporter (residues 72-189) crystal structure with magnesium. | Descriptor: | Calcium uniporter protein, mitochondrial, MAGNESIUM ION | Authors: | Mok, M.C.Y, Lee, S.K, Junop, M.S, Stathopulos, P.B. | Deposit date: | 2016-07-13 | Release date: | 2016-09-07 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural Insights into Mitochondrial Calcium Uniporter Regulation by Divalent Cations. Cell Chem Biol, 23, 2016
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4XSJ
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![BU of 4xsj by Molmil](/molmil-images/mine/4xsj) | Crystal structure of the N-terminal domain of the human mitochondrial calcium uniporter fused with T4 lysozyme | Descriptor: | Lysozyme,Calcium uniporter protein, mitochondrial, SULFATE ION | Authors: | Lee, Y, Min, C.K, Kim, T.G, Song, H.K, Lim, Y, Kim, D, Shin, K, Kang, M, Kang, J.Y, Youn, H.-S, Lee, J.-G, An, J.Y, Park, K.R, Lim, J.J, Kim, J.H, Kim, J.H, Park, Z.Y, Kim, Y.-S, Wang, J, Kim, D.H, Eom, S.H. | Deposit date: | 2015-01-22 | Release date: | 2015-09-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure and function of the N-terminal domain of the human mitochondrial calcium uniporter. Embo Rep., 16, 2015
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5KUG
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![BU of 5kug by Molmil](/molmil-images/mine/5kug) | Human mitochondrial calcium uniporter (residues 72-189) crystal structure with lithium | Descriptor: | Calcium uniporter protein, mitochondrial | Authors: | Mok, M.C.Y, Lee, S.K, Junop, M.S, Stathopulos, P.B. | Deposit date: | 2016-07-13 | Release date: | 2016-09-07 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural Insights into Mitochondrial Calcium Uniporter Regulation by Divalent Cations. Cell Chem Biol, 23, 2016
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6JG0
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![BU of 6jg0 by Molmil](/molmil-images/mine/6jg0) | Crystal structure of the N-terminal domain single mutant (S92E) of the human mitochondrial calcium uniporter fused with T4 lysozyme | Descriptor: | Endolysin,Calcium uniporter protein, SULFATE ION | Authors: | Lee, Y, Park, J, Min, C.K, Kang, J.Y, Kim, T.G, Yamamoto, T, Kim, D.H, Eom, S.H. | Deposit date: | 2019-02-13 | Release date: | 2020-02-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of calcium channel domain To Be Published
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5KUI
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![BU of 5kui by Molmil](/molmil-images/mine/5kui) | Human mitochondrial calcium uniporter (residues 72-189) crystal structure with calcium. | Descriptor: | Calcium uniporter protein, mitochondrial | Authors: | Mok, M.C.Y, Lee, S.K, Junop, M.S, Stathopulos, P.B. | Deposit date: | 2016-07-13 | Release date: | 2016-09-07 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.701 Å) | Cite: | Structural Insights into Mitochondrial Calcium Uniporter Regulation by Divalent Cations. Cell Chem Biol, 23, 2016
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5BZ6
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![BU of 5bz6 by Molmil](/molmil-images/mine/5bz6) | Crystal structure of the N-terminal domain single mutant (S92A) of the human mitochondrial calcium uniporter fused with T4 lysozyme | Descriptor: | Lysozyme,Calcium uniporter protein, mitochondrial, SULFATE ION | Authors: | Lee, Y, Min, C.K, Kim, T.G, Song, H.K, Lim, Y, Kim, D, Shin, K, Kang, M, Kang, J.Y, Youn, H.-S, Lee, J.-G, An, J.Y, Park, K.R, Lim, J.J, Kim, J.H, Kim, J.H, Park, Z.Y, Kim, Y.-S, Wang, J, Kim, D.H, Eom, S.H. | Deposit date: | 2015-06-11 | Release date: | 2015-09-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structure and function of the N-terminal domain of the human mitochondrial calcium uniporter. Embo Rep., 16, 2015
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6KVX
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![BU of 6kvx by Molmil](/molmil-images/mine/6kvx) | Crystal structure of the N-terminal domain single mutant (D119A) of the human mitochondrial calcium uniporter fused with T4 lysozyme | Descriptor: | Endolysin,Calcium uniporter protein, mitochondrial, SULFATE ION | Authors: | Lee, Y, Park, J, Lee, G, Yoon, S, Min, C.K, Kim, T.G, Yamamoto, T, Kim, D.H, Lee, K.W, Eom, S.H. | Deposit date: | 2019-09-05 | Release date: | 2020-05-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Crystal structure of the N-terminal domain single mutant (D119A) of the human mitochondrial calcium uniporter fused with T4 lysozyme Sci Rep, 2020
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6WDN
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![BU of 6wdn by Molmil](/molmil-images/mine/6wdn) | Cryo-EM structure of mitochondrial calcium uniporter holocomplex in low Ca2+ | Descriptor: | Calcium uniporter protein, mitochondrial, Calcium uptake protein 1, ... | Authors: | Feng, L, Zhang, J, Fan, M. | Deposit date: | 2020-04-01 | Release date: | 2020-05-27 | Last modified: | 2020-06-17 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structure and mechanism of the mitochondrial Ca2+uniporter holocomplex. Nature, 582, 2020
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6K7X
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![BU of 6k7x by Molmil](/molmil-images/mine/6k7x) | Human MCU-EMRE complex | Descriptor: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, CALCIUM ION, CARDIOLIPIN, ... | Authors: | Zhuo, W, Zhou, H, Yang, M. | Deposit date: | 2019-06-10 | Release date: | 2020-09-09 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.27 Å) | Cite: | Structure of intact human MCU supercomplex with the auxiliary MICU subunits. Protein Cell, 12, 2021
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6O5B
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![BU of 6o5b by Molmil](/molmil-images/mine/6o5b) | Monomer of a cation channel | Descriptor: | CALCIUM ION, Calcium uniporter protein, mitochondrial, ... | Authors: | Wang, Y, Bai, X, Jiang, Y. | Deposit date: | 2019-03-01 | Release date: | 2019-05-22 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural Mechanism of EMRE-Dependent Gating of the Human Mitochondrial Calcium Uniporter. Cell, 177, 2019
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6WDO
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![BU of 6wdo by Molmil](/molmil-images/mine/6wdo) | Cryo-EM structure of mitochondrial calcium uniporter holocomplex in high Ca2+ | Descriptor: | CALCIUM ION, Calcium uniporter protein, mitochondrial, ... | Authors: | Feng, L, Zhang, J, Fan, M. | Deposit date: | 2020-04-01 | Release date: | 2020-05-27 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure and mechanism of the mitochondrial Ca2+uniporter holocomplex. Nature, 582, 2020
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6K7Y
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![BU of 6k7y by Molmil](/molmil-images/mine/6k7y) | Intact human mitochondrial calcium uniporter complex with MICU1/MICU2 subunits | Descriptor: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, CALCIUM ION, CARDIOLIPIN, ... | Authors: | Zhuo, W, Zhou, H, Yang, M. | Deposit date: | 2019-06-10 | Release date: | 2020-09-09 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure of intact human MCU supercomplex with the auxiliary MICU subunits. Protein Cell, 12, 2021
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6O58
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![BU of 6o58 by Molmil](/molmil-images/mine/6o58) | Human MCU-EMRE complex, dimer of channel | Descriptor: | CALCIUM ION, Calcium uniporter protein, mitochondrial, ... | Authors: | Wang, Y, Bai, X, Jiang, Y. | Deposit date: | 2019-03-01 | Release date: | 2019-05-22 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural Mechanism of EMRE-Dependent Gating of the Human Mitochondrial Calcium Uniporter. Cell, 177, 2019
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6XJV
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![BU of 6xjv by Molmil](/molmil-images/mine/6xjv) | MCU holocomplex in High-calcium state | Descriptor: | Calcium uniporter protein, mitochondrial, Calcium uptake protein 1, ... | Authors: | Wang, Y, Jiang, Y. | Deposit date: | 2020-06-24 | Release date: | 2020-09-09 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.17 Å) | Cite: | Structural insights into the Ca 2+ -dependent gating of the human mitochondrial calcium uniporter. Elife, 9, 2020
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6XJX
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![BU of 6xjx by Molmil](/molmil-images/mine/6xjx) | MCU holocomplex in Low-calcium blocking state | Descriptor: | Calcium uniporter protein, mitochondrial, Calcium uptake protein 1, ... | Authors: | Wang, Y, Jiang, Y. | Deposit date: | 2020-06-24 | Release date: | 2020-09-09 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structural insights into the Ca 2+ -dependent gating of the human mitochondrial calcium uniporter. Elife, 9, 2020
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