3EX7
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2XB2
| Crystal structure of the core Mago-Y14-eIF4AIII-Barentsz-UPF3b assembly shows how the EJC is bridged to the NMD machinery | Descriptor: | EUKARYOTIC INITIATION FACTOR 4A-III, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Buchwald, G, Ebert, J, Basquin, C, Sauliere, J, Jayachandran, U, Bono, F, Le Hir, H, Conti, E. | Deposit date: | 2010-04-03 | Release date: | 2010-05-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Insights Into the Recruitment of the Nmd Machinery from the Crystal Structure of a Core Ejc-Upf3B Complex. Proc.Natl.Acad.Sci.USA, 107, 2010
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6ICZ
| Cryo-EM structure of a human post-catalytic spliceosome (P complex) at 3.0 angstrom | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | Authors: | Zhang, X, Zhan, X, Yan, C, Shi, Y. | Deposit date: | 2018-09-07 | Release date: | 2019-03-13 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structures of the human spliceosomes before and after release of the ligated exon. Cell Res., 29, 2019
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8I0W
| The cryo-EM structure of human C complex | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Coiled-coil domain-containing protein 94, ... | Authors: | Zhan, X, Lu, Y, Shi, Y. | Deposit date: | 2023-01-11 | Release date: | 2024-07-31 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
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5YZG
| The Cryo-EM Structure of Human Catalytic Step I Spliceosome (C complex) at 4.1 angstrom resolution | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Zhan, X, Yan, C, Zhang, X, Lei, J, Shi, Y. | Deposit date: | 2017-12-14 | Release date: | 2018-08-08 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structure of a human catalytic step I spliceosome Science, 359, 2018
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5XJC
| Cryo-EM structure of the human spliceosome just prior to exon ligation at 3.6 angstrom | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Zhang, X, Yan, C, Hang, J, Finci, I.L, Lei, J, Shi, Y. | Deposit date: | 2017-04-30 | Release date: | 2017-07-05 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | An Atomic Structure of the Human Spliceosome Cell, 169, 2017
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7W59
| The cryo-EM structure of human pre-C*-I complex | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | Authors: | Zhan, X, Lu, Y, Shi, Y. | Deposit date: | 2021-11-29 | Release date: | 2022-06-22 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Mechanism of exon ligation by human spliceosome. Mol.Cell, 82, 2022
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7W5A
| The cryo-EM structure of human pre-C*-II complex | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | Authors: | Zhan, X, Lu, Y, Shi, Y. | Deposit date: | 2021-11-29 | Release date: | 2022-06-22 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Mechanism of exon ligation by human spliceosome. Mol.Cell, 82, 2022
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7W5B
| The cryo-EM structure of human C* complex | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | Authors: | Zhan, X, Lu, Y, Shi, Y. | Deposit date: | 2021-11-29 | Release date: | 2022-06-22 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Mechanism of exon ligation by human spliceosome. Mol.Cell, 82, 2022
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2J0Q
| The crystal structure of the Exon Junction Complex at 3.2 A resolution | Descriptor: | 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3', ATP-DEPENDENT RNA HELICASE DDX48, MAGNESIUM ION, ... | Authors: | Bono, F, Ebert, J, Lorentzen, E, Conti, E. | Deposit date: | 2006-08-04 | Release date: | 2006-08-30 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | The Crystal Structure of the Exon Junction Complex Reveals How It Maintains a Stable Grip on Mrna. Cell(Cambridge,Mass.), 126, 2006
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2J0U
| The crystal structure of eIF4AIII-Barentsz complex at 3.0 A resolution | Descriptor: | ATP-DEPENDENT RNA HELICASE DDX48, PROTEIN CASC3 | Authors: | Bono, F, Ebert, J, Lorentzen, E, Conti, E. | Deposit date: | 2006-08-04 | Release date: | 2006-09-06 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The Crystal Structure of the Exon Junction Complex Reveals How It Mantains a Stable Grip on Mrna Cell(Cambridge,Mass.), 126, 2006
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2J0S
| The crystal structure of the Exon Junction Complex at 2.2 A resolution | Descriptor: | 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP *UP*UP*UP*UP*U)-3', ATP-DEPENDENT RNA HELICASE DDX48, MAGNESIUM ION, ... | Authors: | Bono, F, Ebert, J, Lorentzen, E, Conti, E. | Deposit date: | 2006-08-04 | Release date: | 2006-09-06 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | The Crystal Structure of the Exon Junction Complex Reveals How It Mantains a Stable Grip on Mrna Cell(Cambridge,Mass.), 126, 2006
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2HYI
| Structure of the human exon junction complex with a trapped DEAD-box helicase bound to RNA | Descriptor: | 5'-R(*UP*UP*UP*UP*UP*U)-3', MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Andersen, C.B.F, Le Hir, H, Andersen, G.R. | Deposit date: | 2006-08-06 | Release date: | 2006-08-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of the exon junction core complex with a trapped DEAD-box ATPase bound to RNA. Science, 313, 2006
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