3NFK
| Crystal structure of the PTPN4 PDZ domain complexed with the C-terminus of a rabies virus G protein | Descriptor: | GLYCEROL, Glycoprotein G, Tyrosine-protein phosphatase non-receptor type 4 | Authors: | Babault, N, Cordier, F, Lafage, M, Cockburn, J, Haouz, A, Rey, F.A, Delepierre, M, Buc, H, Lafon, M, Wolff, N. | Deposit date: | 2010-06-10 | Release date: | 2011-08-24 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | Peptides Targeting the PDZ Domain of PTPN4 Are Efficient Inducers of Glioblastoma Cell Death. Structure, 19, 2011
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2CSS
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3NFL
| Crystal structure of the PTPN4 PDZ domain complexed with the C-terminus of the GluN2A NMDA receptor subunit | Descriptor: | Glutamate [NMDA] receptor subunit epsilon-1, Tyrosine-protein phosphatase non-receptor type 4 | Authors: | Babault, N, Cordier, F, Lafage, M, Cockburn, J, Haouz, A, Rey, F.A, Delepierre, M, Buc, H, Lafon, M, Wolff, N. | Deposit date: | 2010-06-10 | Release date: | 2011-08-24 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Peptides Targeting the PDZ Domain of PTPN4 Are Efficient Inducers of Glioblastoma Cell Death. Structure, 19, 2011
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3NGH
| Molecular Analysis of the Interaction of the HDL Receptor SR-BI with the Adaptor Protein PDZK1 | Descriptor: | PDZ domain-containing protein 1 | Authors: | Kocher, O, Birrane, G, Krieger, M, Ladias, J.A. | Deposit date: | 2010-06-11 | Release date: | 2010-08-25 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | In vitro and in vivo analysis of the binding of the C terminus of the HDL receptor scavenger receptor class B, type I (SR-BI), to the PDZ1 domain of its adaptor protein PDZK1. J.Biol.Chem., 285, 2010
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2CS5
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2CSJ
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1Q7X
| Solution structure of the alternatively spliced PDZ2 domain (PDZ2b) of PTP-Bas (hPTP1E) | Descriptor: | PDZ2b domain of PTP-Bas (hPTP1E) | Authors: | Kachel, N, Erdmann, K.S, Kremer, W, Wolff, P, Gronwald, W, Heumann, R, Kalbitzer, H.R, Structural Proteomics in Europe (SPINE) | Deposit date: | 2003-08-20 | Release date: | 2003-12-02 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure determination and ligand interactions of the PDZ2b domain of PTP-Bas (hPTP1E): Splicing induced modulation of ligand specificity. J.Mol.Biol., 334, 2003
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6Q0N
| Structure of the Erbin PDB domain in complex with a high-affinity peptide | Descriptor: | Erbin, peptide | Authors: | Singer, A.U, Teyra, J, Ernst, A, Sicheri, F, Sidhu, S.S. | Deposit date: | 2019-08-02 | Release date: | 2019-11-13 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.18 Å) | Cite: | Comprehensive analysis of all evolutionary paths between two divergent PDZ domain specificities. Protein Sci., 29, 2020
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6Q0U
| Structure of the Erbin PDZ variant E-6a with a high-affinity C-terminal peptide | Descriptor: | 1,2-ETHANEDIOL, Erbin, peptide | Authors: | Singer, A.U, Teyra, J, Ernst, A, Sicheri, F, Sidhu, S.S. | Deposit date: | 2019-08-02 | Release date: | 2019-11-13 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Comprehensive analysis of all evolutionary paths between two divergent PDZ domain specificities. Protein Sci., 29, 2020
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6Q0M
| Structure of Erbin PDZ derivative E-14 with a high-affinity peptide | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... | Authors: | Singer, A.U, Teyra, J, Ernst, A, Sicheri, F, Sidhu, S.S. | Deposit date: | 2019-08-02 | Release date: | 2019-11-13 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Comprehensive analysis of all evolutionary paths between two divergent PDZ domain specificities. Protein Sci., 29, 2020
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1QAV
| Unexpected Modes of PDZ Domain Scaffolding Revealed by Structure of NNOS-Syntrophin Complex | Descriptor: | ALPHA-1 SYNTROPHIN (RESIDUES 77-171), NEURONAL NITRIC OXIDE SYNTHASE (RESIDUES 1-130) | Authors: | Hillier, B.J, Christopherson, K.S, Prehoda, K.E, Bredt, D.S, Lim, W.A. | Deposit date: | 1999-03-30 | Release date: | 1999-05-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Unexpected modes of PDZ domain scaffolding revealed by structure of nNOS-syntrophin complex. Science, 284, 1999
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6QJI
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1OZI
| The alternatively spliced PDZ2 domain of PTP-BL | Descriptor: | protein tyrosine phosphatase | Authors: | Walma, T, Aelen, J, Oostendorp, M, van den Berk, L, Hendriks, W, Vuister, G.W. | Deposit date: | 2003-04-09 | Release date: | 2004-01-27 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | A Closed Binding Pocket and Global Destabilization Modify the Binding Properties of an Alternatively Spliced Form of the Second PDZ Domain of PTP-BL. Structure, 12, 2004
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6QJG
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6QJK
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6QJF
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6QJL
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6QJD
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6QJN
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1QLC
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1R6J
| Ultrahigh resolution Crystal Structure of syntenin PDZ2 | Descriptor: | CHLORIDE ION, Syntenin 1 | Authors: | Kang, B.S, Devedjiev, Y, Derewenda, U, Derewenda, Z.S. | Deposit date: | 2003-10-15 | Release date: | 2004-05-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (0.73 Å) | Cite: | The PDZ2 domain of syntenin at ultra-high resolution: bridging the gap between small molecule and macromolecular crystal chemistry J.Mol.Biol., 338, 2004
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1RGR
| Cyclic Peptides Targeting PDZ Domains of PSD-95: Structural Basis for Enhanced Affinity and Enzymatic Stability | Descriptor: | BETA-ALANINE, Presynaptic density protein 95, postsynaptic protein CRIPT peptide | Authors: | Piserchio, A, Salinas, G.D, Li, T, Marshall, J, Spaller, M.R, Mierke, D.F. | Deposit date: | 2003-11-12 | Release date: | 2004-05-18 | Last modified: | 2021-10-27 | Method: | SOLUTION NMR | Cite: | Targeting Specific PDZ Domains of PSD-95; Structural Basis for Enhanced Affinity and Enzymatic Stability of a Cyclic Peptide. Chem.Biol., 11, 2004
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6RLC
| Crystal structure of the PDZ tandem of syntenin in complex with fragment F13 | Descriptor: | (2~{S})-2-[3-(4-chlorophenyl)sulfanylpropanoylamino]-3-methyl-butanoic acid, ACETATE ION, Syntenin-1 | Authors: | Feracci, M, Barral, K. | Deposit date: | 2019-05-02 | Release date: | 2021-02-03 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Pharmacological inhibition of syntenin PDZ2 domain impairs breast cancer cell activities and exosome loadifing with syndecan and EpCAM cargo. J Extracell Vesicles, 10, 2020
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1RGW
| Solution Structure of ZASP's PDZ domain | Descriptor: | ZASP protein | Authors: | Au, Y, Atkinson, R.A, Pallavicini, A, Joseph, C, Martin, S.R, Muskett, F.W, Guerrini, R, Faulkner, G, Pastore, A. | Deposit date: | 2003-11-13 | Release date: | 2004-04-13 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution Structure of ZASP PDZ Domain; Implications for Sarcomere Ultrastructure and Enigma Family Redundancy. Structure, 12, 2004
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6RQR
| Extended NHERF1 PDZ2 domain in complex with the PDZ-binding motif of CFTR | Descriptor: | Na(+)/H(+) exchange regulatory cofactor NHE-RF1,Cystic fibrosis transmembrane conductance regulator | Authors: | Martin, E.R, Ford, R.C, Robinson, R.C. | Deposit date: | 2019-05-16 | Release date: | 2020-02-05 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | In vivocrystals reveal critical features of the interaction between cystic fibrosis transmembrane conductance regulator (CFTR) and the PDZ2 domain of Na+/H+exchange cofactor NHERF1. J.Biol.Chem., 295, 2020
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