7WEG
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![BU of 7weg by Molmil](/molmil-images/mine/7weg) | Complex structure of PDZD7 and FCHSD2 | Descriptor: | FCHSD2, PDZ domain-containing protein 7, ZINC ION | Authors: | Wang, H, Lin, L, Lu, Q. | Deposit date: | 2021-12-23 | Release date: | 2022-11-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Deafness-related protein PDZD7 forms complex with the C-terminal tail of FCHSD2. Biochem.J., 479, 2022
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7X2E
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7XTY
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![BU of 7xty by Molmil](/molmil-images/mine/7xty) | Crystal Structure of the second PDZ domain from human PTPN13 in complex with APC peptide | Descriptor: | APC-peptide, Tyrosine-protein phosphatase non-receptor type 13 | Authors: | Jing, L.Q, Sun, X.N, Ma, W.H, Zhou, W.J, Wu, D.L. | Deposit date: | 2022-05-18 | Release date: | 2023-05-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Targeting PTPN13 with 11 amino acid peptides of C-terminal APC prevents immune evasion of colorectal cancer to be published
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6RQR
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![BU of 6rqr by Molmil](/molmil-images/mine/6rqr) | Extended NHERF1 PDZ2 domain in complex with the PDZ-binding motif of CFTR | Descriptor: | Na(+)/H(+) exchange regulatory cofactor NHE-RF1,Cystic fibrosis transmembrane conductance regulator | Authors: | Martin, E.R, Ford, R.C, Robinson, R.C. | Deposit date: | 2019-05-16 | Release date: | 2020-02-05 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | In vivocrystals reveal critical features of the interaction between cystic fibrosis transmembrane conductance regulator (CFTR) and the PDZ2 domain of Na+/H+exchange cofactor NHERF1. J.Biol.Chem., 295, 2020
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6UBH
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![BU of 6ubh by Molmil](/molmil-images/mine/6ubh) | Structure of the MM7 Erbin PDZ variant in complex with a high-affinity peptide | Descriptor: | Erbin, SODIUM ION, peptide | Authors: | Singer, A.U, Teyra, J, McLaughlin, M, Ernst, A, Sicheri, F, Sidhu, S.S. | Deposit date: | 2019-09-11 | Release date: | 2020-07-29 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Comprehensive Assessment of the Relationship Between Site -2 Specificity and Helix alpha 2 in the Erbin PDZ Domain. J.Mol.Biol., 433, 2021
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6IRE
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![BU of 6ire by Molmil](/molmil-images/mine/6ire) | Complex structure of INAD PDZ45 and NORPA CC-PBM | Descriptor: | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase, Inactivation-no-after-potential D protein | Authors: | Ye, F, Li, J, Deng, X, Liu, W, Zhang, M. | Deposit date: | 2018-11-12 | Release date: | 2019-01-23 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | An unexpected INAD PDZ tandem-mediated plc beta binding in Drosophila photo receptors. Elife, 7, 2018
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6HKS
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6Q0N
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![BU of 6q0n by Molmil](/molmil-images/mine/6q0n) | Structure of the Erbin PDB domain in complex with a high-affinity peptide | Descriptor: | Erbin, peptide | Authors: | Singer, A.U, Teyra, J, Ernst, A, Sicheri, F, Sidhu, S.S. | Deposit date: | 2019-08-02 | Release date: | 2019-11-13 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.18 Å) | Cite: | Comprehensive analysis of all evolutionary paths between two divergent PDZ domain specificities. Protein Sci., 29, 2020
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6Q0U
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![BU of 6q0u by Molmil](/molmil-images/mine/6q0u) | Structure of the Erbin PDZ variant E-6a with a high-affinity C-terminal peptide | Descriptor: | 1,2-ETHANEDIOL, Erbin, peptide | Authors: | Singer, A.U, Teyra, J, Ernst, A, Sicheri, F, Sidhu, S.S. | Deposit date: | 2019-08-02 | Release date: | 2019-11-13 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Comprehensive analysis of all evolutionary paths between two divergent PDZ domain specificities. Protein Sci., 29, 2020
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6Q0M
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![BU of 6q0m by Molmil](/molmil-images/mine/6q0m) | Structure of Erbin PDZ derivative E-14 with a high-affinity peptide | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... | Authors: | Singer, A.U, Teyra, J, Ernst, A, Sicheri, F, Sidhu, S.S. | Deposit date: | 2019-08-02 | Release date: | 2019-11-13 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Comprehensive analysis of all evolutionary paths between two divergent PDZ domain specificities. Protein Sci., 29, 2020
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6QJJ
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6QJD
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6QJN
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6QJI
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6QJF
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6QJL
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6QJG
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6QJK
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6JUE
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![BU of 6jue by Molmil](/molmil-images/mine/6jue) | The complex of PDZ and PBM | Descriptor: | Partitioning defective 3 homolog, SULFATE ION, THR-ILE-ILE-THR-LEU | Authors: | Liu, Z. | Deposit date: | 2019-04-13 | Release date: | 2020-04-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.549 Å) | Cite: | Par complex cluster formation mediated by phase separation. Nat Commun, 11, 2020
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6LCB
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![BU of 6lcb by Molmil](/molmil-images/mine/6lcb) | Crystal structure of human Dishevelled1 PDZ domain with its inhibitor NPL3009 | Descriptor: | 2-[[3-[(2E)-2-[1,3-bis(oxidanylidene)-1-phenyl-butan-2-ylidene]hydrazinyl]phenyl]sulfonylamino]benzoic acid, SULFATE ION, Segment polarity protein dishevelled homolog DVL-1 | Authors: | Yasukochi, S, Numoto, N, Tenno, N, Tenno, T, Ito, N, Hiroaki, H. | Deposit date: | 2019-11-18 | Release date: | 2020-11-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystal structure of human Dishevelled1 PDZ domain with its inhibitor NPL3009 To Be Published
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1I92
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![BU of 1i92 by Molmil](/molmil-images/mine/1i92) | STRUCTURAL BASIS OF THE NHERF PDZ1-CFTR INTERACTION | Descriptor: | CHLORIDE ION, NA+/H+ EXCHANGE REGULATORY CO-FACTOR | Authors: | Karthikeyan, S, Leung, T, Ladias, J.A.A. | Deposit date: | 2001-03-16 | Release date: | 2001-06-27 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis of the Na+/H+ exchanger regulatory factor PDZ1 interaction with the carboxyl-terminal region of the cystic fibrosis transmembrane conductance regulator. J.Biol.Chem., 276, 2001
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1IU2
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![BU of 1iu2 by Molmil](/molmil-images/mine/1iu2) | The first PDZ domain of PSD-95 | Descriptor: | PSD-95 | Authors: | Long, J.-F, Tochio, H, Wang, P, Sala, C, Niethammer, M, Sheng, M, Zhang, M. | Deposit date: | 2002-02-19 | Release date: | 2003-03-11 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Supramodular structure and synergistic target binding of the N-terminal tandem PDZ domains of PSD-95 J.MOL.BIOL., 327, 2003
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1KWA
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![BU of 1kwa by Molmil](/molmil-images/mine/1kwa) | HUMAN CASK/LIN-2 PDZ DOMAIN | Descriptor: | HCASK/LIN-2 PROTEIN, SULFATE ION | Authors: | Daniels, D.L, Cohen, A.R, Anderson, J.M, Brunger, A.T. | Deposit date: | 1998-01-16 | Release date: | 1998-05-27 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Crystal structure of the hCASK PDZ domain reveals the structural basis of class II PDZ domain target recognition Nat.Struct.Biol., 5, 1998
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1L6O
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![BU of 1l6o by Molmil](/molmil-images/mine/1l6o) | XENOPUS DISHEVELLED PDZ DOMAIN | Descriptor: | Dapper 1, Segment polarity protein dishevelled homolog DVL-2 | Authors: | Cheyette, B.N.R, Waxman, J.S, Miller, J.R, Takemaru, K.-I, Sheldahl, L.C, Khlebtsova, N, Fox, E.P, Earnest, T, Moon, R.T. | Deposit date: | 2002-03-11 | Release date: | 2003-06-03 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Dapper, a Dishevelled-associated antagonist of beta-catenin and JNK signaling, is required for notochord formation Dev.Cell, 2, 2002
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1KEF
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![BU of 1kef by Molmil](/molmil-images/mine/1kef) | PDZ1 of SAP90 | Descriptor: | synapse associated protein-90 | Authors: | Piserchio, A, Pellegrini, M, Mehta, S, Blackman, S.M, Garcia, E.P, Marshall, J, Mierke, D.F. | Deposit date: | 2001-11-15 | Release date: | 2002-03-06 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The PDZ1 domain of SAP90. Characterization of structure and binding. J.Biol.Chem., 277, 2002
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