6LCB

Crystal structure of human Dishevelled1 PDZ domain with its inhibitor NPL3009

Summary for 6LCB

• Entry DOI: 10.2210/pdb6lcb/pdb
• Descriptor: Segment polarity protein dishevelled homolog DVL-1, 2-[[3-[(2E)-2-[1,3-bis(oxidanylidene)-1-phenyl-butan-2-ylidene]hydrazinyl]phenyl]sulfonylamino]benzoic acid, SULFATE ION, ... (4 entities in total)
• Functional Keywords: wnt signaling pathway, signaling protein, developmental protein, protein binding, dvl, inhibitor of protein-protein interactions
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 11332.60

Authors

Yasukochi, S.,Numoto, N.,Tenno, N.,Tenno, T.,Ito, N.,Hiroaki, H. (deposition date: 2019-11-18, release date: 2020-11-25, Last modification date: 2023-11-22)

• Primary citation: Yasukochi, S.,Numoto, N.,Tenno, N.,Tenno, T.,Ito, N.,Hiroaki, H.; Crystal structure of human Dishevelled1 PDZ domain with its inhibitor NPL3009; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.4 Å)