5ULK
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8ODR
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![BU of 8odr by Molmil](/molmil-images/mine/8odr) | Mimetic of UBC9-SUMO1 | Descriptor: | SULFATE ION, SUMO-conjugating enzyme UBC9, Small ubiquitin-related modifier 1 | Authors: | Coste, F, Goffinont, S, Suskiewicz, M.J. | Deposit date: | 2023-03-09 | Release date: | 2023-06-07 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Structural insights into the regulation of the human E2∼SUMO conjugate through analysis of its stable mimetic. J.Biol.Chem., 299, 2023
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5ULH
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3RPG
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![BU of 3rpg by Molmil](/molmil-images/mine/3rpg) | Bmi1/Ring1b-UbcH5c complex structure | Descriptor: | E3 ubiquitin-protein ligase RING2, Polycomb complex protein BMI-1, Ubiquitin-conjugating enzyme E2 D3, ... | Authors: | Bentley, M.L, Dong, K.C, Cochran, A.G. | Deposit date: | 2011-04-26 | Release date: | 2011-08-17 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.6485 Å) | Cite: | Recognition of UbcH5c and the nucleosome by the Bmi1/Ring1b ubiquitin ligase complex. Embo J., 30, 2011
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6IF1
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![BU of 6if1 by Molmil](/molmil-images/mine/6if1) | Crystal structure of Ube2K and K48-linked di-ubiquitin complex | Descriptor: | Ubiquitin, Ubiquitin-conjugating enzyme E2 K | Authors: | Lee, J.-G, Youn, H.-S, Lee, Y, An, J.Y, Park, K.R, Kang, J.Y, Lim, J.J, Eom, S.H. | Deposit date: | 2018-09-18 | Release date: | 2018-11-21 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.466 Å) | Cite: | Crystal structure of the Ube2K/E2-25K and K48-linked di-ubiquitin complex provides structural insight into the mechanism of K48-specific ubiquitin chain synthesis. Biochem. Biophys. Res. Commun., 506, 2018
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3VON
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![BU of 3von by Molmil](/molmil-images/mine/3von) | Crystalstructure of the ubiquitin protease | Descriptor: | Ubiquitin thioesterase OTUB1, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2 | Authors: | Sato, Y, Fukai, S. | Deposit date: | 2012-01-30 | Release date: | 2012-05-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Molecular basis of Lys-63-linked polyubiquitination inhibition by the interaction between human deubiquitinating enzyme OTUB1 and ubiquitin-conjugating enzyme UBC13. J.Biol.Chem., 287, 2012
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3W31
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![BU of 3w31 by Molmil](/molmil-images/mine/3w31) | Structual basis for the recognition of Ubc13 by the Shigella flexneri effector OspI | Descriptor: | IODIDE ION, ORF169b, Ubiquitin-conjugating enzyme E2 N | Authors: | Nishide, A, Kim, M, Takagi, K, Sasakawa, C, Mizushima, T. | Deposit date: | 2012-12-07 | Release date: | 2013-03-27 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.96 Å) | Cite: | Structural basis for the recognition of Ubc13 by the Shigella flexneri effector OspI. J.Mol.Biol., 425, 2013
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6HPR
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6JKY
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6GUM
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![BU of 6gum by Molmil](/molmil-images/mine/6gum) | Structure of the A.thaliana E1 UFD domain in complex with E2 | Descriptor: | GLYCEROL, SAE2, SUMO-conjugating enzyme SCE1 | Authors: | Liu, B, Lois, L.M, Reverter, D. | Deposit date: | 2018-06-19 | Release date: | 2019-07-03 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.792 Å) | Cite: | Structural insights into SUMO E1-E2 interactions in Arabidopsis uncovers a distinctive platform for securing SUMO conjugation specificity across evolution. Biochem.J., 476, 2019
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6JB7
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![BU of 6jb7 by Molmil](/molmil-images/mine/6jb7) | Crystal structure of Ub-conjugated Ube2K C92K&K97A mutant (isopeptide linkage), 2.1 A resolution | Descriptor: | Ubiquitin, Ubiquitin-conjugating enzyme E2 K | Authors: | Lee, J.-G, Youn, H.-S, Lee, Y, An, J.Y, Park, K.R, Kang, J.Y, Mun, S.A, Park, J, Park, T, Jin, M.W, Yang, J, Eom, S.H. | Deposit date: | 2019-01-25 | Release date: | 2019-03-20 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of Ub-conjugated Ube2K C92K&K97A mutant (isopeptide linkage), 2.1 A resolution To Be Published
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6JB6
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![BU of 6jb6 by Molmil](/molmil-images/mine/6jb6) | Crystal structure of Ub-conjugated Ube2K C92K&K97A mutant (isopeptide linkage), 2.7 A resolution | Descriptor: | Ubiquitin, Ubiquitin-conjugating enzyme E2 K | Authors: | Lee, J.-G, Youn, H.-S, Lee, Y, An, J.Y, Park, K.R, Kang, J.Y, Mun, S.A, Park, J, Park, T, Jin, M.W, Yang, J, Eom, S.H. | Deposit date: | 2019-01-25 | Release date: | 2019-03-20 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of Ub-conjugated Ube2K C92K&K97A mutant (isopeptide linkage), 2.7 A resolution To Be Published
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4AP4
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![BU of 4ap4 by Molmil](/molmil-images/mine/4ap4) | Rnf4 - ubch5a - ubiquitin heterotrimeric complex | Descriptor: | E3 UBIQUITIN LIGASE RNF4, UBIQUITIN C, UBIQUITIN-CONJUGATING ENZYME E2 D1, ... | Authors: | Plechanovova, A, Hay, R.T, Tatham, M.H, Jaffray, E, Naismith, J.H. | Deposit date: | 2012-03-30 | Release date: | 2012-07-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Structure of a Ring E3 Ligase and Ubiquitin-Loaded E2 Primed for Catalysis Nature, 489, 2012
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7UN6
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![BU of 7un6 by Molmil](/molmil-images/mine/7un6) | Complex of UBE2O with NAP1L1 | Descriptor: | (E3-independent) E2 ubiquitin-conjugating enzyme, Nucleosome assembly protein 1-like 1 | Authors: | Yip, M.C.J, Sedor, S.F, Shao, S. | Deposit date: | 2022-04-09 | Release date: | 2022-08-03 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Mechanism of client selection by the protein quality-control factor UBE2O. Nat.Struct.Mol.Biol., 29, 2022
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7UN3
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![BU of 7un3 by Molmil](/molmil-images/mine/7un3) | Complex of UBE2O with NAP1L1 and ubiquitylated uL2 | Descriptor: | Nucleosome assembly protein 1-like 1, Ubiquitin,60S ribosomal protein L8,(E3-independent) E2 ubiquitin-conjugating enzyme fusion | Authors: | Yip, M.C.J, Sedor, S.F, Shao, S. | Deposit date: | 2022-04-08 | Release date: | 2022-08-03 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Mechanism of client selection by the protein quality-control factor UBE2O. Nat.Struct.Mol.Biol., 29, 2022
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6KFP
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![BU of 6kfp by Molmil](/molmil-images/mine/6kfp) | Crystal structure of MavC ternary complex | Descriptor: | MavC, Ubiquitin-40S ribosomal protein S27a, Ubiquitin-conjugating enzyme E2 N | Authors: | Mu, Y, Wang, Y, Han, Y, Li, D, Feng, Y. | Deposit date: | 2019-07-08 | Release date: | 2020-04-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.92 Å) | Cite: | Structural insights into the mechanism and inhibition of transglutaminase-induced ubiquitination by the Legionella effector MavC. Nat Commun, 11, 2020
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4JQU
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![BU of 4jqu by Molmil](/molmil-images/mine/4jqu) | Crystal structure of Ubc7p in complex with the U7BR of Cue1p | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Coupling of ubiquitin conjugation to ER degradation protein 1, DI(HYDROXYETHYL)ETHER, ... | Authors: | Liang, Y.-H, Metzger, M.B, Weissman, A.M, Ji, X. | Deposit date: | 2013-03-20 | Release date: | 2013-05-29 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | A Structurally Unique E2-Binding Domain Activates Ubiquitination by the ERAD E2, Ubc7p, through Multiple Mechanisms. Mol.Cell, 50, 2013
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8EAZ
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![BU of 8eaz by Molmil](/molmil-images/mine/8eaz) | HOIL-1/E2-Ub/Ub transthiolation complex | Descriptor: | RanBP-type and C3HC4-type zinc finger-containing protein 1, Ubiquitin, Ubiquitin-conjugating enzyme E2 L3, ... | Authors: | Wang, X.S, Cotton, T.R, Lechtenberg, B.C. | Deposit date: | 2022-08-30 | Release date: | 2023-01-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.08 Å) | Cite: | The unifying catalytic mechanism of the RING-between-RING E3 ubiquitin ligase family. Nat Commun, 14, 2023
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8EB0
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![BU of 8eb0 by Molmil](/molmil-images/mine/8eb0) | RNF216/E2-Ub/Ub transthiolation complex | Descriptor: | E3 ubiquitin-protein ligase RNF216, SULFATE ION, Ubiquitin, ... | Authors: | Cotton, T.R, Wang, X.S, Lechtenberg, B.C. | Deposit date: | 2022-08-30 | Release date: | 2023-01-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.03 Å) | Cite: | The unifying catalytic mechanism of the RING-between-RING E3 ubiquitin ligase family. Nat Commun, 14, 2023
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8E2D
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![BU of 8e2d by Molmil](/molmil-images/mine/8e2d) | Cryo-EM structure of BIRC6 (consensus) | Descriptor: | Baculoviral IAP repeat-containing protein 6 | Authors: | Hunkeler, M, Fischer, E.S. | Deposit date: | 2022-08-15 | Release date: | 2023-02-15 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.07 Å) | Cite: | Structures of BIRC6-client complexes provide a mechanism of SMAC-mediated release of caspases. Science, 379, 2023
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8E2G
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8E2E
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8E2I
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![BU of 8e2i by Molmil](/molmil-images/mine/8e2i) | Cryo-EM structure of BIRC6/Smac | Descriptor: | Baculoviral IAP repeat-containing protein 6, Diablo IAP-binding mitochondrial protein | Authors: | Hunkeler, M, Fischer, E.S. | Deposit date: | 2022-08-15 | Release date: | 2023-02-15 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.04 Å) | Cite: | Structures of BIRC6-client complexes provide a mechanism of SMAC-mediated release of caspases. Science, 379, 2023
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8E2F
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8E2K
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![BU of 8e2k by Molmil](/molmil-images/mine/8e2k) | Cryo-EM structure of BIRC6/HtrA2-S306A | Descriptor: | Baculoviral IAP repeat-containing protein 6, Serine protease HTRA2, mitochondrial | Authors: | Hunkeler, M, Fischer, E.S. | Deposit date: | 2022-08-15 | Release date: | 2023-02-15 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.21 Å) | Cite: | Structures of BIRC6-client complexes provide a mechanism of SMAC-mediated release of caspases. Science, 379, 2023
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