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PDB: 329 results

3B6G
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BU of 3b6g by Molmil
Nucleosome core particle treated with oxaliplatin
Descriptor: 147-MER DNA, Histone H2A, Histone H2B 1.1, ...
Authors:Wu, B, Davey, C.A.
Deposit date:2007-10-29
Release date:2007-12-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Site selectivity of platinum anticancer therapeutics
Nat.Chem.Biol., 4, 2008
8T3Y
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BU of 8t3y by Molmil
Structure of Bre1-nucleosome complex - state1
Descriptor: 601 DNA Strand 1, 601 DNA Strand 2, E3 ubiquitin-protein ligase BRE1, ...
Authors:Zhao, F, Hicks, C.W, Wolberger, C.
Deposit date:2023-06-08
Release date:2023-10-18
Last modified:2023-11-22
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Mechanism of histone H2B monoubiquitination by Bre1.
Nat.Struct.Mol.Biol., 30, 2023
6IY2
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BU of 6iy2 by Molmil
Structure of Snf2-MMTV-A nucleosome complex at shl2 in ADP state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA (147-MER), DNA (167-MER), ...
Authors:Li, M, Xia, X, Liu, X, Li, X, Chen, Z.
Deposit date:2018-12-12
Release date:2019-04-03
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Mechanism of DNA translocation underlying chromatin remodelling by Snf2.
Nature, 567, 2019
8G6S
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BU of 8g6s by Molmil
H2AK119ub-modified nucleosome ubiquitin position 2
Descriptor: 601 DNA (145-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Hicks, C.W, Wolberger, C.
Deposit date:2023-02-15
Release date:2024-02-21
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Ubiquitinated H2B as gatekeeper of the nucleosome acidic patch
To Be Published
8EUE
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BU of 8eue by Molmil
Class1 of the INO80-Nucleosome complex
Descriptor: DNA (147-MER), Histone H2A type 1, Histone H2B 1.1, ...
Authors:Wu, H, Munoz, E, Gourdet, M, Narlikar, G, Cheng, Y.F.
Deposit date:2022-10-18
Release date:2023-07-12
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (3.48 Å)
Cite:Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility.
Science, 381, 2023
7XD0
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BU of 7xd0 by Molmil
cryo-EM structure of H2BK34ub nucleosome
Descriptor: DNA (146-MER), Histone H2A, Histone H2B type 1-K, ...
Authors:Ai, H.S, Liu, A.J, Lou, Z.Y, Liu, L.
Deposit date:2022-03-26
Release date:2022-04-20
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.48 Å)
Cite:H2B Lys34 Ubiquitination Induces Nucleosome Distortion to Stimulate Dot1L Activity.
Nat.Chem.Biol., 18, 2022
6O96
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BU of 6o96 by Molmil
Dot1L bound to the H2BK120 Ubiquitinated nucleosome
Descriptor: DNA (146-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Valencia-Sanchez, M.I, De Ioannes, P.E, Miao, W, Vasilyev, N, Chen, R, Nudler, E, Armache, J.-P, Armache, K.-J.
Deposit date:2019-03-13
Release date:2019-04-24
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural Basis of Dot1L Stimulation by Histone H2B Lysine 120 Ubiquitination.
Mol.Cell, 74, 2019
8OL1
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BU of 8ol1 by Molmil
cGAS-Nucleosome in complex with SPSB3-ELOBC (composite structure)
Descriptor: Cyclic GMP-AMP synthase, DNA (145-MER), Elongin-B, ...
Authors:Xu, P.B, Ablasser, A.
Deposit date:2023-03-29
Release date:2024-02-14
Last modified:2024-04-10
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:The CRL5-SPSB3 ubiquitin ligase targets nuclear cGAS for degradation.
Nature, 627, 2024
6UH5
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BU of 6uh5 by Molmil
Structural basis of COMPASS eCM recognition of the H2Bub nucleosome
Descriptor: Bre2, DNA (146-MER), H3 N-terminus, ...
Authors:Hsu, P.L, Shi, H, Zheng, N.
Deposit date:2019-09-26
Release date:2019-11-20
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural Basis of H2B Ubiquitination-Dependent H3K4 Methylation by COMPASS.
Mol.Cell, 76, 2019
7KBE
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BU of 7kbe by Molmil
Nucleosome isolated from metaphase chromosome formed in Xenopus egg extract (oligo fraction)
Descriptor: DNA (157-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Arimura, Y, Funabiki, H.
Deposit date:2020-10-02
Release date:2021-09-15
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural features of nucleosomes in interphase and metaphase chromosomes.
Mol.Cell, 81, 2021
3KWQ
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BU of 3kwq by Molmil
Structural characterization of H3K56Q nucleosomes and nucleosomal arrays
Descriptor: DNA (146-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Lilyestrom, W.G, Clark, N.
Deposit date:2009-12-01
Release date:2010-05-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural characterization of H3K56Q nucleosomes and nucleosomal arrays.
Biochim.Biophys.Acta, 1799
6WKR
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BU of 6wkr by Molmil
PRC2-AEBP2-JARID2 bound to H2AK119ub1 nucleosome
Descriptor: DNA (314-MER), Histone H2A type 1, Histone H2B 1.1, ...
Authors:Kasinath, V, Nogales, E, Beck, C, Sauer, P, Poepsel, S, Kosmatka, J, Faini, M, Toso, D, Aebersold, R.
Deposit date:2020-04-16
Release date:2021-02-03
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:JARID2 and AEBP2 regulate PRC2 in the presence of H2AK119ub1 and other histone modifications.
Science, 371, 2021
7BU9
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BU of 7bu9 by Molmil
Crystal Structure of Spindlin1-H3(K4me3-K9me2) complex
Descriptor: H3(K4me3-K9me2) peptide, Spindlin-1
Authors:Zhao, F, Li, H.
Deposit date:2020-04-05
Release date:2020-10-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.502 Å)
Cite:Molecular basis for histone H3 "K4me3-K9me3/2" methylation pattern readout by Spindlin1.
J.Biol.Chem., 295, 2020
6NQA
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BU of 6nqa by Molmil
Active state Dot1L bound to the H2B-Ubiquitinated nucleosome, 1-to-1 complex
Descriptor: 601 DNA Strand 1, 601 DNA Strand 2, Histone H2A type 1, ...
Authors:Worden, E.J, Hoffmann, N.A, Wolberger, C.
Deposit date:2019-01-19
Release date:2019-02-20
Last modified:2020-01-08
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Mechanism of Cross-talk between H2B Ubiquitination and H3 Methylation by Dot1L.
Cell, 176, 2019
8IHM
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BU of 8ihm by Molmil
Eaf3 CHD domain bound to the nucleosome
Descriptor: Chromatin modification-related protein EAF3, DNA (164-MER), DNA (165-MER), ...
Authors:Zhang, Y, Gang, C.
Deposit date:2023-02-23
Release date:2024-03-20
Method:ELECTRON MICROSCOPY (3.58 Å)
Cite:Structural basis for nucleosome binding and catalysis by the yeast Rpd3S/HDAC holoenzyme.
Cell Res., 33, 2023
8CEO
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BU of 8ceo by Molmil
Yeast RNA polymerase II transcription pre-initiation complex with core Mediator and the +1 nucleosome
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Wang, H, Cramer, P.
Deposit date:2023-02-02
Release date:2023-03-08
Last modified:2023-04-19
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Yeast PIC-Mediator structure with RNA polymerase II C-terminal domain.
Proc.Natl.Acad.Sci.USA, 120, 2023
6T9L
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BU of 6t9l by Molmil
SAGA DUB module bound to a ubiqitinated nucleosome
Descriptor: Histone H2A, Histone H2B, Histone H2B 1.1, ...
Authors:Wang, H, Cramer, P.
Deposit date:2019-10-28
Release date:2020-01-29
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure of the transcription coactivator SAGA.
Nature, 577, 2020
5Z3O
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BU of 5z3o by Molmil
Structure of Snf2-nucleosome complex in ADP state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA (167-MER), Histone H2A, ...
Authors:Li, M, Xia, X, Liu, X, Li, X, Chen, Z.
Deposit date:2018-01-08
Release date:2019-04-03
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.62 Å)
Cite:Mechanism of DNA translocation underlying chromatin remodelling by Snf2.
Nature, 567, 2019
6IY3
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BU of 6iy3 by Molmil
Structure of Snf2-MMTV-A nucleosome complex at shl-2 in ADP state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA (147-MER), Histone H2A, ...
Authors:Li, M, Xia, X, Liu, X, Li, X, Chen, Z.
Deposit date:2018-12-12
Release date:2019-04-03
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.67 Å)
Cite:Mechanism of DNA translocation underlying chromatin remodelling by Snf2.
Nature, 567, 2019
6ESF
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BU of 6esf by Molmil
Nucleosome : Class 1
Descriptor: DNA (147-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Bilokapic, S, Halic, M.
Deposit date:2017-10-20
Release date:2017-12-20
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Histone octamer rearranges to adapt to DNA unwrapping.
Nat. Struct. Mol. Biol., 25, 2018
6T7A
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BU of 6t7a by Molmil
Structure of human Sox11 transcription factor in complex with a nucleosome
Descriptor: DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ...
Authors:Dodonova, S.O, Zhu, F, Dienemann, C, Taipale, J, Cramer, P.
Deposit date:2019-10-21
Release date:2020-04-29
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function.
Nature, 580, 2020
8IHT
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BU of 8iht by Molmil
Rpd3S bound to the nucleosome
Descriptor: CALCIUM ION, Chromatin modification-related protein EAF3, DNA (164-MER), ...
Authors:Zhang, Y, Gang, C.
Deposit date:2023-02-23
Release date:2024-03-20
Method:ELECTRON MICROSCOPY (3.72 Å)
Cite:Structural basis for nucleosome binding and catalysis by the yeast Rpd3S/HDAC holoenzyme.
Cell Res., 33, 2023
8BZ1
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BU of 8bz1 by Molmil
RNA polymerase II core pre-initiation complex with the proximal +1 nucleosome (cPIC-Nuc10W)
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB11-a, ...
Authors:Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P.
Deposit date:2022-12-14
Release date:2023-05-03
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis of transcription reduction by a promoter-proximal +1 nucleosome.
Mol.Cell, 83, 2023
7PF5
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BU of 7pf5 by Molmil
Nucleosome 2 of the 4x187 nucleosome array containing H1
Descriptor: DNA (167-MER), Histone H1.4, Histone H2A type 1-B/E, ...
Authors:Dombrowski, M, Cramer, P.
Deposit date:2021-08-11
Release date:2022-08-03
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Histone H1 binding to nucleosome arrays depends on linker DNA length and trajectory.
Nat.Struct.Mol.Biol., 29, 2022
6FQ5
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BU of 6fq5 by Molmil
Class 1 : canonical nucleosome
Descriptor: DNA (147-MER), Histone H2A, Histone H2B, ...
Authors:Bilokapic, S, Halic, M.
Deposit date:2018-02-13
Release date:2018-04-18
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural rearrangements of the histone octamer translocate DNA.
Nat Commun, 9, 2018

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數據於2024-07-10公開中

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