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PDB: 329 results

3MGR
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BU of 3mgr by Molmil
Binding of Rubidium ions to the Nucleosome Core Particle
Descriptor: CHLORIDE ION, DNA (147-MER), Histone H2A, ...
Authors:Mohideen, K, Muhammad, R, Davey, C.A.
Deposit date:2010-04-07
Release date:2010-06-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Perturbations in nucleosome structure from heavy metal association.
Nucleic Acids Res., 38, 2010
8G88
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BU of 8g88 by Molmil
Human Oct4 bound to nucleosome with human nMatn1 sequence
Descriptor: Histone H2A, Histone H2B, Histone H3, ...
Authors:Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M.
Deposit date:2023-02-17
Release date:2023-03-22
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Histone modifications regulate pioneer transcription factor cooperativity.
Nature, 619, 2023
8G86
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BU of 8g86 by Molmil
Human Oct4 bound to nucleosome with human nMatn1 sequence (focused refinement of nucleosome)
Descriptor: Histone H2A, Histone H2B, Histone H3, ...
Authors:Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M.
Deposit date:2023-02-17
Release date:2023-03-22
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Histone modifications regulate pioneer transcription factor cooperativity.
Nature, 619, 2023
7TN2
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BU of 7tn2 by Molmil
Composite model of a Chd1-nucleosome complex in the nucleotide-free state derived from 2.3A and 2.7A Cryo-EM maps
Descriptor: Chromo domain-containing protein 1, DNA Lagging Strand, DNA Tracking Strand, ...
Authors:Nodelman, I.M, Bowman, G.D, Armache, J.-P.
Deposit date:2022-01-20
Release date:2022-03-02
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Nucleosome recognition and DNA distortion by the Chd1 remodeler in a nucleotide-free state.
Nat.Struct.Mol.Biol., 29, 2022
1P3I
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BU of 1p3i by Molmil
Crystallographic Studies of Nucleosome Core Particles containing Histone 'Sin' Mutants
Descriptor: Histone H2A, Histone H2B, Histone H3, ...
Authors:Muthurajan, U.M, Bao, Y, Forsberg, L.J, Edayathumangalam, R.S, Dyer, P.N, White, C.L, Luger, K.
Deposit date:2003-04-17
Release date:2004-02-24
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of histone Sin mutant nucleosomes reveal altered protein-DNA interactions
EMBO J., 23, 2004
5OMX
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BU of 5omx by Molmil
X-ray Structure of the H2A-N38C Nucleosome Core Particle
Descriptor: CHLORIDE ION, DNA (147-MER), Histone H2A, ...
Authors:Frouws, T.D, Richmond, T.J.
Deposit date:2017-08-02
Release date:2017-11-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Site-Specific Disulfide Crosslinked Nucleosomes with Enhanced Stability.
J. Mol. Biol., 430, 2018
4EO5
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BU of 4eo5 by Molmil
Yeast Asf1 bound to H3/H4G94P mutant
Descriptor: ACETATE ION, GLYCEROL, Histone H3.2, ...
Authors:Scorgie, J.K, Churchill, M.E.
Deposit date:2012-04-13
Release date:2012-06-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:The conformational flexibility of the C-terminus of histone H4 promotes histone octamer and nucleosome stability and yeast viability.
Epigenetics Chromatin, 5, 2012
8JLB
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BU of 8jlb by Molmil
Cryo-EM structure of the 145 bp human nucleosome containing H3.2 C110A mutant
Descriptor: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
Authors:Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H.
Deposit date:2023-06-02
Release date:2023-10-04
Last modified:2023-11-08
Method:ELECTRON MICROSCOPY (2.36 Å)
Cite:Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II.
Nucleic Acids Res., 51, 2023
4J8U
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BU of 4j8u by Molmil
X-ray structure of NCP145 with chlorido(eta-6-p-cymene)(N-phenyl-2-pyridinecarbothioamide)osmium(II)
Descriptor: DNA, Histone H2A type 1, Histone H2B 1.1, ...
Authors:Adhireksan, Z, Davey, C.A.
Deposit date:2013-02-15
Release date:2013-04-17
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Novel metal(II) arene 2-pyridinecarbothioamides: a rationale to orally active organometallic anticancer agents
CHEM SCI, 4, 2013
1P3L
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BU of 1p3l by Molmil
Crystallographic Studies of Nucleosome Core Particles containing Histone 'Sin' Mutants
Descriptor: Histone H2A, Histone H2B, Histone H3, ...
Authors:Muthurajan, U.M, Bao, Y, Forsberg, L.J, Edayathumangalam, R.S, Dyer, P.N, White, C.L, Luger, K.
Deposit date:2003-04-17
Release date:2004-02-24
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of histone Sin mutant nucleosomes reveal altered protein-DNA interactions
EMBO J., 23, 2004
4XZQ
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BU of 4xzq by Molmil
Nucleosome disassembly by RSC and SWI/SNF is enhanced by H3 acetylation near the nucleosome dyad axis
Descriptor: DNA (147-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Dechassa, M.L, Luger, K, Chatterjee, N, North, J.A, Manohar, M, Prasad, R, Ottessen, J.J, Poirier, M.G, Bartholomew, B.
Deposit date:2015-02-04
Release date:2015-10-14
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Histone Acetylation near the Nucleosome Dyad Axis Enhances Nucleosome Disassembly by RSC and SWI/SNF.
Mol.Cell.Biol., 35, 2015
3DB3
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BU of 3db3 by Molmil
Crystal structure of the tandem tudor domains of the E3 ubiquitin-protein ligase UHRF1 in complex with trimethylated histone H3-K9 peptide
Descriptor: E3 ubiquitin-protein ligase UHRF1, Trimethylated histone H3-K9 peptide
Authors:Walker, J.R, Avvakumov, G.V, Xue, S, Dong, A, Li, Y, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2008-05-30
Release date:2008-09-16
Last modified:2012-04-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Recognition of multivalent histone states associated with heterochromatin by UHRF1 protein.
J.Biol.Chem., 286, 2011
4J8W
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BU of 4j8w by Molmil
X-ray structure of NCP145 with chlorido(eta-6-p-cymene)(N-fluorophenyl-2-pyridinecarbothioamide)osmium(II)
Descriptor: DNA (145-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Adhireksan, Z, Davey, C.A.
Deposit date:2013-02-15
Release date:2013-04-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Novel metal(II) arene 2-pyridinecarbothioamides: a rationale to orally active organometallic anticancer agents
CHEM SCI, 4, 2013
3MGP
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BU of 3mgp by Molmil
Binding of Cobalt ions to the Nucleosome Core Particle
Descriptor: CHLORIDE ION, COBALT (II) ION, DNA (147-MER), ...
Authors:Mohideen, K, Muhammad, R, Davey, C.A.
Deposit date:2010-04-07
Release date:2010-06-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Perturbations in nucleosome structure from heavy metal association.
Nucleic Acids Res., 38, 2010
4WU8
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BU of 4wu8 by Molmil
Structure of trPtNAP-NCP145
Descriptor: DNA (145-MER), Histone H2A type 1, Histone H2B 1.1, ...
Authors:Chua, E.Y.D, Davey, C.A.
Deposit date:2014-10-31
Release date:2015-09-02
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Stereochemical control of nucleosome targeting by platinum-intercalator antitumor agents.
Nucleic Acids Res., 43, 2015
8JLD
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BU of 8jld by Molmil
Cryo-EM structure of the 145 bp human nucleosome containing acetylated H3 tail
Descriptor: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
Authors:Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H.
Deposit date:2023-06-02
Release date:2023-10-04
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.48 Å)
Cite:Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II.
Nucleic Acids Res., 51, 2023
3LZ0
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BU of 3lz0 by Molmil
Crystal Structure of Nucleosome Core Particle Composed of the Widom 601 DNA Sequence (orientation 1)
Descriptor: CHLORIDE ION, DNA (145-MER), Histone H2A, ...
Authors:Vasudevan, D, Chua, E.Y.D, Davey, C.A.
Deposit date:2010-03-01
Release date:2010-09-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of nucleosome core particles containing the '601' strong positioning sequence
J.Mol.Biol., 403, 2010
3LZ1
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BU of 3lz1 by Molmil
Crystal Structure of Nucleosome Core Particle Composed of the Widom 601 DNA Sequence (orientation 2)
Descriptor: CHLORIDE ION, DNA (145-MER), Histone H2A, ...
Authors:Vasudevan, D, Chua, E.Y.D, Davey, C.A.
Deposit date:2010-03-01
Release date:2010-09-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of nucleosome core particles containing the '601' strong positioning sequence
J.Mol.Biol., 403, 2010
3REH
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BU of 3reh by Molmil
2.5 Angstrom Crystal Structure of the Nucleosome Core Particle Assembled with a 145 bp Alpha-Satellite DNA (NCP145)
Descriptor: DNA (145-MER), Histone H2A type 1, Histone H2B 1.1, ...
Authors:Wu, B, Davey, C.A.
Deposit date:2011-04-04
Release date:2012-03-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Specific DNA structural attributes modulate platinum anticancer drug site selection and cross-link generation.
Nucleic Acids Res., 39, 2011
3MNN
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BU of 3mnn by Molmil
A Ruthenium Antitumour Agent Forms Specific Histone Protein Adducts in the Nucleosome Core
Descriptor: 1,3,5-triaza-7-phosphatricyclo[3.3.1.1~3,7~]decane, 1-methyl-4-(1-methylethyl)benzene, DNA (145-MER), ...
Authors:Ong, M.S, Davey, C.A.
Deposit date:2010-04-22
Release date:2011-04-06
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A ruthenium antimetastasis agent forms specific histone protein adducts in the nucleosome core
Chemistry, 17, 2011
4Z66
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BU of 4z66 by Molmil
Nucleosome disassembly by RSC and SWI/SNF is enhanced by H3 acetylation near the nucleosome dyad axis
Descriptor: DNA (147-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Dechassa, M.L, Luger, K, Chatterjee, N, North, J.A, Manohar, M, Prasad, R, Ottessen, J.J, Poirier, M.G, Bartholomew, B.
Deposit date:2015-04-03
Release date:2015-10-14
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Histone Acetylation near the Nucleosome Dyad Axis Enhances Nucleosome Disassembly by RSC and SWI/SNF.
Mol.Cell.Biol., 35, 2015
3AV1
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BU of 3av1 by Molmil
The human nucleosome structure containing the histone variant H3.2
Descriptor: 146-MER DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ...
Authors:Tachiwana, H, Osakabe, A, Shiga, T, Miya, Y, Kimura, H, Kagawa, W, Kurumizaka, H.
Deposit date:2011-02-18
Release date:2011-06-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of human nucleosomes containing major histone H3 variants
Acta Crystallogr.,Sect.D, 67, 2011
7OHC
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BU of 7ohc by Molmil
Cryo-EM structure of nucleosome core particle composed of the Widom 601 DNA sequence
Descriptor: DNA (145-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Wang, H, Cramer, P.
Deposit date:2021-05-10
Release date:2021-07-28
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structures and implications of TBP-nucleosome complexes.
Proc.Natl.Acad.Sci.USA, 118, 2021
6ZHX
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BU of 6zhx by Molmil
Cryo-EM structure of the regulatory linker of ALC1 bound to the nucleosome's acidic patch: nucleosome class.
Descriptor: Chromodomain-helicase-DNA-binding protein 1-like, DNA (145-MER) Widom 601 sequence, Histone H2A type 1, ...
Authors:Bacic, L, Gaullier, G, Croll, T.I, Deindl, S.
Deposit date:2020-06-24
Release date:2020-12-23
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Mechanistic Insights into Regulation of the ALC1 Remodeler by the Nucleosome Acidic Patch.
Cell Rep, 33, 2020
3REJ
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BU of 3rej by Molmil
2.55 Angstrom Crystal Structure of the Nucleosome Core Particle Assembled with a 146 bp Alpha-Satellite DNA (NCP146b)
Descriptor: DNA (146-MER), Histone H2A type 1, Histone H2B 1.1, ...
Authors:Wu, B, Davey, C.A.
Deposit date:2011-04-04
Release date:2012-03-14
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Specific DNA structural attributes modulate platinum anticancer drug site selection and cross-link generation.
Nucleic Acids Res., 39, 2011

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數據於2024-07-10公開中

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