3IUC
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![BU of 3iuc by Molmil](/molmil-images/mine/3iuc) | Crystal structure of the human 70kDa heat shock protein 5 (BiP/GRP78) ATPase domain in complex with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Heat shock 70kDa protein 5 (Glucose-regulated protein, ... | Authors: | Wisniewska, M, Karlberg, T, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Kotyenova, T, Kotzch, A, Kraulis, P, Markova, N, Moche, M, Nielsen, T.K, Nordlund, P, Nyman, T, Persson, C, Roos, A, Schutz, P, Siponen, M.I, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Schuler, H, Structural Genomics Consortium (SGC) | Deposit date: | 2009-08-31 | Release date: | 2009-09-22 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structures of the ATPase domains of four human Hsp70 isoforms: HSPA1L/Hsp70-hom, HSPA2/Hsp70-2, HSPA6/Hsp70B', and HSPA5/BiP/GRP78 Plos One, 5, 2010
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4MJS
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![BU of 4mjs by Molmil](/molmil-images/mine/4mjs) | crystal structure of a PB1 complex | Descriptor: | 1,2-ETHANEDIOL, Protein kinase C zeta type, Sequestosome-1 | Authors: | Ren, J, Wang, Z.X, Wu, J.W. | Deposit date: | 2013-09-04 | Release date: | 2014-08-27 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural and biochemical insights into the homotypic PB1-PB1 complex between PKC zeta and p62 Sci China Life Sci, 57, 2014
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5YPA
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![BU of 5ypa by Molmil](/molmil-images/mine/5ypa) | p62/SQSTM1 ZZ domain with Lys-peptide | Descriptor: | 78 kDa glucose-regulated protein,Sequestosome-1, ZINC ION | Authors: | Kwon, D.H, Kim, L, Song, H.K. | Deposit date: | 2017-11-01 | Release date: | 2018-08-29 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.502 Å) | Cite: | Insights into degradation mechanism of N-end rule substrates by p62/SQSTM1 autophagy adapter. Nat Commun, 9, 2018
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6DFO
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![BU of 6dfo by Molmil](/molmil-images/mine/6dfo) | Crystal structure of human GRP78 in complex with 8-bromoadenosine | Descriptor: | 8-bromoadenosine, Endoplasmic reticulum chaperone BiP | Authors: | Ferrie, R.P, Chen, Y, Antoshchenko, T, Cooney, O.M, Huang, Y, Park, H.W. | Deposit date: | 2018-05-15 | Release date: | 2019-05-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | Crystal structure of human GRP78 in complex with 8-bromoadenosine To be Published
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5E85
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![BU of 5e85 by Molmil](/molmil-images/mine/5e85) | isolated SBD of BiP | Descriptor: | 78 kDa glucose-regulated protein, SULFATE ION | Authors: | Liu, Q, Yang, J, Nune, M, Zong, Y, Zhou, L. | Deposit date: | 2015-10-13 | Release date: | 2015-12-30 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | Close and Allosteric Opening of the Polypeptide-Binding Site in a Human Hsp70 Chaperone BiP. Structure, 23, 2015
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6ZMD
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![BU of 6zmd by Molmil](/molmil-images/mine/6zmd) | Crystal structure of HYPE covalently tethered to BiP bound to AMP-PNP | Descriptor: | Endoplasmic reticulum chaperone BiP, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Fauser, J, Gulen, B, Pett, C, Hedberg, C, Itzen, A, Pogenberg, V. | Deposit date: | 2020-07-02 | Release date: | 2021-04-14 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.64 Å) | Cite: | Specificity of AMPylation of the human chaperone BiP is mediated by TPR motifs of FICD. Nat Commun, 12, 2021
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5E86
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![BU of 5e86 by Molmil](/molmil-images/mine/5e86) | isolated SBD of BiP with loop34 modification | Descriptor: | 78 kDa glucose-regulated protein | Authors: | Liu, Q, Yang, J, Nune, M, Zong, Y, Zhou, L. | Deposit date: | 2015-10-13 | Release date: | 2015-12-30 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.681 Å) | Cite: | Close and Allosteric Opening of the Polypeptide-Binding Site in a Human Hsp70 Chaperone BiP. Structure, 23, 2015
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6KHZ
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![BU of 6khz by Molmil](/molmil-images/mine/6khz) | p62/SQSTM1 ZZ domain with Gly-peptide | Descriptor: | Sequestosome-1, ZINC ION | Authors: | Kwon, D.H, Kim, L, Song, H.K. | Deposit date: | 2019-07-16 | Release date: | 2020-01-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Use of the LC3B-fusion technique for biochemical and structural studies of proteins involved in the N-degron pathway. J.Biol.Chem., 295, 2020
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5YPE
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![BU of 5ype by Molmil](/molmil-images/mine/5ype) | p62/SQSTM1 ZZ domain with Tyr-peptide | Descriptor: | 78 kDa glucose-regulated protein,Sequestosome-1, ZINC ION | Authors: | Kwon, D.H, Kim, L, Song, H.K. | Deposit date: | 2017-11-01 | Release date: | 2018-08-29 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.851 Å) | Cite: | Insights into degradation mechanism of N-end rule substrates by p62/SQSTM1 autophagy adapter. Nat Commun, 9, 2018
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5YPB
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![BU of 5ypb by Molmil](/molmil-images/mine/5ypb) | p62/SQSTM1 ZZ domain with His-peptide | Descriptor: | 78 kDa glucose-regulated protein,Sequestosome-1, ZINC ION | Authors: | Kwon, D.H, Kim, L, Song, H.K. | Deposit date: | 2017-11-01 | Release date: | 2018-08-29 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Insights into degradation mechanism of N-end rule substrates by p62/SQSTM1 autophagy adapter. Nat Commun, 9, 2018
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5YPF
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![BU of 5ypf by Molmil](/molmil-images/mine/5ypf) | p62/SQSTM1 ZZ domain with Trp-peptide | Descriptor: | 78 kDa glucose-regulated protein,Sequestosome-1, ZINC ION | Authors: | Kwon, D.H, Kim, L, Song, H.K. | Deposit date: | 2017-11-01 | Release date: | 2018-08-29 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.951 Å) | Cite: | Insights into degradation mechanism of N-end rule substrates by p62/SQSTM1 autophagy adapter. Nat Commun, 9, 2018
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5E84
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![BU of 5e84 by Molmil](/molmil-images/mine/5e84) | ATP-bound state of BiP | Descriptor: | 78 kDa glucose-regulated protein, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Liu, Q, Yang, J, Nune, M, Zong, Y, Zhou, L. | Deposit date: | 2015-10-13 | Release date: | 2016-01-27 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.99 Å) | Cite: | Close and Allosteric Opening of the Polypeptide-Binding Site in a Human Hsp70 Chaperone BiP. Structure, 23, 2015
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6JM4
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![BU of 6jm4 by Molmil](/molmil-images/mine/6jm4) | |
6TGY
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![BU of 6tgy by Molmil](/molmil-images/mine/6tgy) | |
6TH3
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![BU of 6th3 by Molmil](/molmil-images/mine/6th3) | |
4UF9
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![BU of 4uf9 by Molmil](/molmil-images/mine/4uf9) | Electron cryo-microscopy structure of PB1-p62 type T filaments | Descriptor: | SEQUESTOSOME-1 | Authors: | Ciuffa, R, Lamark, T, Tarafder, A, Guesdon, A, Rybina, S, Hagen, W.J.H, Johansen, T, Sachse, C. | Deposit date: | 2015-03-15 | Release date: | 2015-05-13 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (10.3 Å) | Cite: | The Selective Autophagy Receptor P62 Forms a Flexible Filamentous Helical Scaffold. Cell Rep., 11, 2015
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4UF8
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![BU of 4uf8 by Molmil](/molmil-images/mine/4uf8) | Electron cryo-microscopy structure of PB1-p62 filaments | Descriptor: | SEQUESTOSOME-1 | Authors: | Ciuffa, R, Lamark, T, Tarafder, A, Guesdon, A, Rybina, S, Hagen, W.J.H, Johansen, T, Sachse, C. | Deposit date: | 2015-03-15 | Release date: | 2015-05-13 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (10.9 Å) | Cite: | The Selective Autophagy Receptor P62 Forms a Flexible Filamentous Helical Scaffold. Cell Rep., 11, 2015
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2JY8
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![BU of 2jy8 by Molmil](/molmil-images/mine/2jy8) | |
1Q02
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![BU of 1q02 by Molmil](/molmil-images/mine/1q02) | NMR structure of the UBA domain of p62 (SQSTM1) | Descriptor: | sequestosome 1 | Authors: | Ciani, B, Layfield, R, Cavey, J.R, Sheppard, P.W, Searle, M.S. | Deposit date: | 2003-07-15 | Release date: | 2003-09-30 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure of the Ubiquitin-associated Domain of p62 (SQSTM1) and Implications for Mutations That Cause Paget's
Disease of Bone J.Biol.Chem., 278, 2003
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2K0B
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![BU of 2k0b by Molmil](/molmil-images/mine/2k0b) | NMR structure of the UBA domain of p62 (SQSTM1) | Descriptor: | Sequestosome-1 | Authors: | Long, J.E, Ciani, B, Gallagher, T.R.A, Cavey, J.R, Sheppard, P.W, Layfield, R, Searle, M.S. | Deposit date: | 2008-01-31 | Release date: | 2008-02-19 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Conformation and dynamics of the three-helix bundle UBA domain of p62 from experiment and simulation. Proteins, 71, 2007
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2KNV
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![BU of 2knv by Molmil](/molmil-images/mine/2knv) | |
2JY7
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![BU of 2jy7 by Molmil](/molmil-images/mine/2jy7) | |