2JY7

NMR structure of the ubiquitin associated (UBA) domain of p62 (SQSTM1). RDC refined

Summary for 2JY7

• Entry DOI: 10.2210/pdb2jy7/pdb
• Related: 2JY8
• NMR Information: BMRB: 15591
• Descriptor: Ubiquitin-binding protein p62 (1 entity in total)
• Functional Keywords: ubiquitin binding, ubiquitin associated domain, helical bundle, three helices, alternative splicing, apoptosis, cytoplasm, differentiation, disease mutation, endosome, immune response, metal-binding, nucleus, phosphoprotein, polymorphism, zinc, zinc-finger, protein binding
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 5744.41

Authors

Long, J.E.,Layfield, R.,Searle, M.S. (deposition date: 2007-12-07, release date: 2007-12-18, Last modification date: 2020-02-19)

• Primary citation: Long, J.,Gallagher, T.R.,Cavey, J.R.,Sheppard, P.W.,Ralston, S.H.,Layfield, R.,Searle, M.S.; Ubiquitin Recognition by the Ubiquitin-associated Domain of p62 Involves a Novel Conformational Switch; J.Biol.Chem., 283:5427-5440, 2008; PubMed: 18083707; DOI: 10.1074/jbc.M704973200

Experimental method

SOLUTION NMR