3PKA
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![BU of 3pka by Molmil](/molmil-images/mine/3pka) | M. tuberculosis MetAP with bengamide analog Y02, in Mn form | Descriptor: | (2R,3R,4S,5R,6E)-3,4,5-trihydroxy-2-methoxy-8,8-dimethyl-N-[2-(2,4,6-trimethylphenoxy)ethyl]non-6-enamide, CHLORIDE ION, MANGANESE (II) ION, ... | Authors: | Ye, Q.Z, Lu, J.P. | Deposit date: | 2010-11-11 | Release date: | 2011-04-20 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives. Chemmedchem, 6, 2011
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3PKB
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![BU of 3pkb by Molmil](/molmil-images/mine/3pkb) | M. tuberculosis MetAP with bengamide analog Y16, in Mn form | Descriptor: | (E,2R,3R,4S,5R)-N-(2-azanyl-2-oxidanylidene-ethyl)-2-methoxy-8,8-dimethyl-3,4,5-tris(oxidanyl)non-6-enamide, CHLORIDE ION, MANGANESE (II) ION, ... | Authors: | Ye, Q.Z, Lu, J.P. | Deposit date: | 2010-11-11 | Release date: | 2011-04-20 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives. Chemmedchem, 6, 2011
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3IU7
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![BU of 3iu7 by Molmil](/molmil-images/mine/3iu7) | |
3PKD
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![BU of 3pkd by Molmil](/molmil-images/mine/3pkd) | M. tuberculosis MetAP with bengamide analog Y10, in Mn form | Descriptor: | (E,2R,3R,4S,5R)-N-(2,3-dihydro-1H-inden-2-yl)-2-methoxy-8,8-dimethyl-3,4,5-tris(oxidanyl)non-6-enamide, MANGANESE (II) ION, Methionine aminopeptidase | Authors: | Ye, Q.Z, Lu, J.P. | Deposit date: | 2010-11-11 | Release date: | 2011-04-20 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives. Chemmedchem, 6, 2011
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3PKC
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![BU of 3pkc by Molmil](/molmil-images/mine/3pkc) | M. tuberculosis MetAP with bengamide analog Y08, in Mn form | Descriptor: | (E,2R,3R,4S,5R)-N-[[(3S)-1-cyclopropylcarbonylpiperidin-3-yl]methyl]-2-methoxy-8,8-dimethyl-3,4,5-tris(oxidanyl)non-6-enamide, MANGANESE (II) ION, Methionine aminopeptidase | Authors: | Ye, Q.Z, Lu, J.P. | Deposit date: | 2010-11-11 | Release date: | 2011-04-20 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives. Chemmedchem, 6, 2011
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1Y1N
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![BU of 1y1n by Molmil](/molmil-images/mine/1y1n) | Identification of SH3 motif in M. Tuberculosis methionine aminopeptidase suggests a mode of interaction with the ribosome | Descriptor: | Methionine aminopeptidase 1B, POTASSIUM ION | Authors: | Addlagatta, A, Quillin, M.L, Omotoso, O, Liu, J.O, Matthews, B.W. | Deposit date: | 2004-11-18 | Release date: | 2005-05-24 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Identification of an SH3-Binding Motif in a New Class of Methionine Aminopeptidases from Mycobacterium tuberculosis Suggests a Mode of Interaction with the Ribosome Biochemistry, 44, 2005
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1YJ3
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![BU of 1yj3 by Molmil](/molmil-images/mine/1yj3) | Crystal structure analysis of product bound methionine aminopeptidase Type 1c from Mycobacterium Tuberculosis | Descriptor: | BETA-MERCAPTOETHANOL, COBALT (II) ION, METHIONINE, ... | Authors: | Addlagatta, A, Quillin, M.L, Omotoso, O, Liu, J.O, Matthews, B.W. | Deposit date: | 2005-01-13 | Release date: | 2005-07-05 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Identification of an SH3-binding motif in a new class of methionine aminopeptidases from Mycobacterium tuberculosis suggests a mode of interaction with the ribosome. Biochemistry, 44, 2005
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3PKE
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![BU of 3pke by Molmil](/molmil-images/mine/3pke) | M. tuberculosis MetAP with bengamide analog Y10, in Ni form | Descriptor: | (E,2R,3R,4S,5R)-N-(2,3-dihydro-1H-inden-2-yl)-2-methoxy-8,8-dimethyl-3,4,5-tris(oxidanyl)non-6-enamide, CHLORIDE ION, Methionine aminopeptidase, ... | Authors: | Ye, Q.Z, Lu, J.P. | Deposit date: | 2010-11-11 | Release date: | 2011-04-20 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives. Chemmedchem, 6, 2011
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3IU9
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![BU of 3iu9 by Molmil](/molmil-images/mine/3iu9) | M. tuberculosis methionine aminopeptidase with Ni inhibitor T07 | Descriptor: | 5-[(2,4-dichlorobenzyl)sulfanyl]-4H-1,2,4-triazol-3-amine, CHLORIDE ION, Methionine aminopeptidase, ... | Authors: | Ye, Q.Z, Lu, J.P. | Deposit date: | 2009-08-30 | Release date: | 2010-01-12 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Catalysis and Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidase J.Med.Chem., 53, 2010
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3IU8
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![BU of 3iu8 by Molmil](/molmil-images/mine/3iu8) | M. tuberculosis methionine aminopeptidase with Ni inhibitor T03 | Descriptor: | 3-[(4-fluorobenzyl)sulfanyl]-4H-1,2,4-triazole, CHLORIDE ION, Methionine aminopeptidase, ... | Authors: | Ye, Q.Z, Lu, J.P. | Deposit date: | 2009-08-30 | Release date: | 2010-01-12 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Catalysis and Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidase J.Med.Chem., 53, 2010
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4OOK
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![BU of 4ook by Molmil](/molmil-images/mine/4ook) | Third Metal bound M.tuberculosis methionine aminopeptidase | Descriptor: | COBALT (II) ION, Methionine aminopeptidase 2, SODIUM ION | Authors: | Reddi, R, Addlagatta, A. | Deposit date: | 2014-02-03 | Release date: | 2015-02-04 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Selective targeting of the conserved active site cysteine of Mycobacterium tuberculosis methionine aminopeptidase with electrophilic reagents Febs J., 281, 2014
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3ROR
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![BU of 3ror by Molmil](/molmil-images/mine/3ror) | |
4IDY
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![BU of 4idy by Molmil](/molmil-images/mine/4idy) | Mycobacterium Tuberculosis Methionine aminopeptidase Type 1c in complex with 2-hydroxyethyl disulfide | Descriptor: | 2-HYDROXYETHYL DISULFIDE, Methionine aminopeptidase 2, POTASSIUM ION | Authors: | Reddi, R, Gumpena, R, Kishor, C, Addlagatta, A. | Deposit date: | 2012-12-13 | Release date: | 2013-12-18 | Last modified: | 2015-02-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Selective targeting of the conserved active site cysteine of Mycobacterium tuberculosis methionine aminopeptidase with electrophilic reagents Febs J., 281, 2014
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4IF7
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![BU of 4if7 by Molmil](/molmil-images/mine/4if7) | Mycobacterium Tuberculosis Methionine aminopeptidase Type 1c in complex with homocysteine-methyl disulfide | Descriptor: | (2S)-2-amino-4-(methyldisulfanyl)butanoic acid, COBALT (II) ION, Methionine aminopeptidase 2 | Authors: | Reddi, R, Gumpena, R, Kishor, C, Addlagatta, A. | Deposit date: | 2012-12-14 | Release date: | 2013-12-18 | Last modified: | 2019-11-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Selective targeting of the conserved active site cysteine of Mycobacterium tuberculosis methionine aminopeptidase with electrophilic reagents Febs J., 281, 2014
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4IEC
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![BU of 4iec by Molmil](/molmil-images/mine/4iec) | Cys105 covalent modification by 2-hydroxyethyl disulfide in Mycobacterium tuberculosis methionine aminopeptidase Type 1c | Descriptor: | COBALT (II) ION, Methionine aminopeptidase 2, POTASSIUM ION | Authors: | Reddi, R, Gumpena, R, Kishor, C, Addlagatta, A. | Deposit date: | 2012-12-13 | Release date: | 2013-12-18 | Last modified: | 2019-11-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Selective targeting of the conserved active site cysteine of Mycobacterium tuberculosis methionine aminopeptidase with electrophilic reagents Febs J., 281, 2014
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