9CZN
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9CZP
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8KF4
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8KF1
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8KF5
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8KF3
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8KF6
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8KEW
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8X53
| Cryo-EM structure of human gamma-secretase in complex with Abeta46 | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Guo, X, Yan, C, Lei, J, Zhou, R, Shi, Y. | Deposit date: | 2023-11-16 | Release date: | 2024-05-29 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Molecular mechanism of substrate recognition and cleavage by human gamma-secretase. Science, 384, 2024
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8X54
| Cryo-EM structure of human gamma-secretase in complex with APP-C99 | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Guo, X, Yan, C, Lei, J, Zhou, R, Shi, Y. | Deposit date: | 2023-11-16 | Release date: | 2024-05-29 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Molecular mechanism of substrate recognition and cleavage by human gamma-secretase. Science, 384, 2024
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8X52
| Cryo-EM structure of human gamma-secretase in complex with Abeta49 | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Guo, X, Yan, C, Lei, J, Zhou, R, Shi, Y. | Deposit date: | 2023-11-16 | Release date: | 2024-05-29 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Molecular mechanism of substrate recognition and cleavage by human gamma-secretase. Science, 384, 2024
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8SEJ
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8SEK
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8SEL
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8KH2
| Crystal structure of horse-spleen L-ferritin fused with amyloid beta peptide (1-42). | Descriptor: | CADMIUM ION, CHLORIDE ION, Ferritin light chain,Amyloid-beta precursor protein (Fragment), ... | Authors: | Maity, B, Tian, J, Abe, S, Ueno, T. | Deposit date: | 2023-08-21 | Release date: | 2024-04-03 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Fusion of amyloid beta with ferritin yields an isolated oligomeric beta-sheet-rich aggregate inside the ferritin cage. Biomater Sci, 12, 2024
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8OTF
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8OWJ
| Lipidic amyloid-beta(1-40) fibril - polymorph L2-L2 | Descriptor: | Amyloid-beta A4 protein | Authors: | Frieg, B, Han, M, Giller, K, Dienemann, C, Riedel, D, Becker, S, Andreas, L.B, Griesinger, C, Schroeder, G.F. | Deposit date: | 2023-04-28 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.75 Å) | Cite: | Cryo-EM structures of lipidic fibrils of amyloid-beta (1-40). Nat Commun, 15, 2024
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8OVM
| Lipidic amyloid-beta(1-40) fibril - polymorph L2 | Descriptor: | Amyloid-beta A4 protein | Authors: | Frieg, B, Han, M, Giller, K, Dienemann, C, Riedel, D, Becker, S, Andreas, L.B, Griesinger, C, Schroeder, G.F. | Deposit date: | 2023-04-26 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.24 Å) | Cite: | Cryo-EM structures of lipidic fibrils of amyloid-beta (1-40). Nat Commun, 15, 2024
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8OWE
| Lipidic amyloid-beta(1-40) fibril - polymorph L2-L3 | Descriptor: | Amyloid-beta A4 protein | Authors: | Frieg, B, Han, M, Giller, K, Dienemann, C, Riedel, D, Becker, S, Andreas, L.B, Griesinger, C, Schroeder, G.F. | Deposit date: | 2023-04-27 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.75 Å) | Cite: | Cryo-EM structures of lipidic fibrils of amyloid-beta (1-40). Nat Commun, 15, 2024
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8OVK
| Lipidic amyloid-beta(1-40) fibril - polymorph L1 | Descriptor: | Amyloid-beta A4 protein | Authors: | Frieg, B, Han, M, Giller, K, Dienemann, C, Riedel, D, Becker, S, Andreas, L.B, Griesinger, C, Schroeder, G.F. | Deposit date: | 2023-04-26 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (2.88 Å) | Cite: | Cryo-EM structures of lipidic fibrils of amyloid-beta (1-40). Nat Commun, 15, 2024
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8OWK
| Lipidic amyloid-beta(1-40) fibril - polymorph L3-L3 | Descriptor: | Amyloid-beta A4 protein | Authors: | Frieg, B, Han, M, Giller, K, Dienemann, C, Riedel, D, Becker, S, Andreas, L.B, Griesinger, C, Schroeder, G.F. | Deposit date: | 2023-04-28 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.86 Å) | Cite: | Cryo-EM structures of lipidic fibrils of amyloid-beta (1-40). Nat Commun, 15, 2024
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8OWD
| Lipidic amyloid-beta(1-40) fibril - polymorph L3 | Descriptor: | Amyloid-beta A4 protein | Authors: | Frieg, B, Han, M, Giller, K, Dienemann, C, Riedel, D, Becker, S, Andreas, L.B, Griesinger, C, Schroeder, G.F. | Deposit date: | 2023-04-27 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.28 Å) | Cite: | Cryo-EM structures of lipidic fibrils of amyloid-beta (1-40). Nat Commun, 15, 2024
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8OT1
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8OT3
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8OT4
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