2F5S
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![BU of 2f5s by Molmil](/molmil-images/mine/2f5s) | Catalytically inactive (E3Q) MutM crosslinked to oxoG:C containing DNA CC1 | Descriptor: | 5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*TP*CP*GP*GP*AP*CP*GP*C)-3', 5'-D(*TP*GP*C*GP*TP*CP*CP*(8OG)P*AP*GP*TP*CP*TP*AP*CP*C)-3', ZINC ION, ... | Authors: | Banerjee, A, Santos, W.L, Verdine, G.L. | Deposit date: | 2005-11-26 | Release date: | 2006-03-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structure of a DNA glycosylase searching for lesions. Science, 311, 2006
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2F7E
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![BU of 2f7e by Molmil](/molmil-images/mine/2f7e) | PKA complexed with (S)-2-(1H-Indol-3-yl)-1-(5-isoquinolin-6-yl-pyridin-3-yloxymethyl-etylamine | Descriptor: | (1S)-2-(1H-INDOL-3-YL)-1-{[(5-ISOQUINOLIN-6-YLPYRIDIN-3-YL)OXY]METHYL}ETHYLAMINE, PKI inhibitory peptide, cAMP-dependent protein kinase, ... | Authors: | Stoll, V.S. | Deposit date: | 2005-11-30 | Release date: | 2006-06-27 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Synthesis and structure-activity relationship of 3,4'-bispyridinylethylenes: discovery of a potent 3-isoquinolinylpyridine inhibitor of protein kinase B (PKB/Akt) for the treatment of cancer. Bioorg.Med.Chem.Lett., 16, 2006
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2F8Y
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![BU of 2f8y by Molmil](/molmil-images/mine/2f8y) | Crystal structure of human Notch1 ankyrin repeats to 1.55A resolution. | Descriptor: | Notch homolog 1, translocation-associated (Drosophila), SULFATE ION | Authors: | Nam, Y, Sliz, P, Blacklow, S.C. | Deposit date: | 2005-12-04 | Release date: | 2006-04-04 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes. Cell(Cambridge,Mass.), 124, 2006
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2FL5
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2ES7
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![BU of 2es7 by Molmil](/molmil-images/mine/2es7) | Crystal structure of Q8ZP25 from Salmonella typhimurium LT2. NESG TARGET STR70 | Descriptor: | putative thiol-disulfide isomerase and thioredoxin | Authors: | Benach, J, Su, M, Forouhar, F, Chen, Y, Ho, C.K, Janjua, H, Cunningham, K, Ma, L.-C, Rong, X, Liu, J, Baran, M, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2005-10-25 | Release date: | 2005-11-01 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of Q8ZP25 from Salmonella typhimurium LT2 NESG target STR70. To be Published
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2FDM
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![BU of 2fdm by Molmil](/molmil-images/mine/2fdm) | Crystal structure of the ternary complex of signalling glycoprotein frm sheep (SPS-40)with hexasaccharide (NAG6) and peptide Trp-Pro-Trp at 3.0A resolution | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, Chitinase-3-like protein 1, ... | Authors: | Srivastava, D.B, Ethayathulla, A.S, Kumar, J, Somvanshi, R.K, Sharma, S, Singh, T.P. | Deposit date: | 2005-12-14 | Release date: | 2006-01-10 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of the ternary complex of signalling glycoprotein frm sheep (SPS-40)
with hexasaccharide (NAG6) and peptide Trp-Pro-Trp at 3.0A resolution To be Published
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2ECK
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![BU of 2eck by Molmil](/molmil-images/mine/2eck) | STRUCTURE OF PHOSPHOTRANSFERASE | Descriptor: | ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ADENYLATE KINASE | Authors: | Berry, M.B, Bilderback, T, Glaser, M, Phillips Jr, G.N. | Deposit date: | 1996-12-16 | Release date: | 1997-03-12 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of ADP/AMP complex of Escherichia coli adenylate kinase. Proteins, 62, 2006
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2EFQ
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![BU of 2efq by Molmil](/molmil-images/mine/2efq) | Crystal Structure of Thr134 to Ala of ST1022-Glutamine Complex from Sulfolobus tokodaii 7 | Descriptor: | 150aa long hypothetical transcriptional regulator, GLUTAMINE, MAGNESIUM ION | Authors: | Kumarevel, T.S, Karthe, P, Nakano, N, Shinkai, A, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-02-23 | Release date: | 2008-03-04 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of glutamine receptor protein from Sulfolobus tokodaii strain 7 in complex with its effector L-glutamine: implications of effector binding in molecular association and DNA binding. Nucleic Acids Res., 36, 2008
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2EG3
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![BU of 2eg3 by Molmil](/molmil-images/mine/2eg3) | Crystal Structure of Probable Thiosulfate Sulfurtransferase | Descriptor: | Probable thiosulfate sulfurtransferase, SULFATE ION, ZINC ION | Authors: | Sakai, H, Ebihara, A, Kitamura, Y, Shinkai, A, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-02-27 | Release date: | 2008-03-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structure of Probable Thiosulfate Sulfurtransferase To be Published
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2EJF
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![BU of 2ejf by Molmil](/molmil-images/mine/2ejf) | Crystal Structure Of The Biotin Protein Ligase (Mutations R48A and K111A) and Biotin Carboxyl Carrier Protein Complex From Pyrococcus Horikoshii OT3 | Descriptor: | 149aa long hypothetical methylmalonyl-CoA decarboxylase gamma chain, 235aa long hypothetical biotin--[acetyl-CoA-carboxylase] ligase, ADENOSINE, ... | Authors: | Bagautdinov, B, Matsuura, Y, Bagautdinova, S, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-03-16 | Release date: | 2008-03-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Protein biotinylation visualized by a complex structure of biotin protein ligase with a substrate J.Biol.Chem., 283, 2008
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2EJY
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2ELA
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![BU of 2ela by Molmil](/molmil-images/mine/2ela) | Crystal Structure of the PTB domain of human APPL1 | Descriptor: | Adapter protein containing PH domain, PTB domain and leucine zipper motif 1 | Authors: | Li, J, Mao, X, Dong, L.Q, Liu, F, Tong, L. | Deposit date: | 2007-03-27 | Release date: | 2007-05-29 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structures of the BAR-PH and PTB Domains of Human APPL1 Structure, 15, 2007
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2E08
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![BU of 2e08 by Molmil](/molmil-images/mine/2e08) | |
2E24
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![BU of 2e24 by Molmil](/molmil-images/mine/2e24) | crystal structure of a mutant (R612A) of xanthan lyase | Descriptor: | DI(HYDROXYETHYL)ETHER, Xanthan lyase | Authors: | Maruyama, Y, Mikami, B, Hashimoto, W, Murata, K. | Deposit date: | 2006-11-07 | Release date: | 2007-01-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | A Structural Factor Responsible for Substrate Recognition by Bacillus sp. GL1 Xanthan Lyase that Acts Specifically on Pyruvated Side Chains of Xanthan Biochemistry, 46, 2007
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2E2O
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![BU of 2e2o by Molmil](/molmil-images/mine/2e2o) | Crystal structure of Sulfolobus tokodaii hexokinase in complex with glucose | Descriptor: | HEXOKINASE, beta-D-glucopyranose | Authors: | Nishimasu, H, Fushinobu, S, Shoun, H, Wakagi, T. | Deposit date: | 2006-11-15 | Release date: | 2007-01-16 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal structures of an ATP-dependent hexokinase with broad substrate specificity from the hyperthermophilic archaeon Sulfolobus tokodaii. J.Biol.Chem., 282, 2007
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2E40
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![BU of 2e40 by Molmil](/molmil-images/mine/2e40) | Crystal structure of intracellular family 1 beta-glucosidase BGL1A from the basidiomycete Phanerochaete chrysosporium in complex with gluconolactone | Descriptor: | Beta-glucosidase, D-glucono-1,5-lactone | Authors: | Nijikken, Y, Tsukada, T, Igarashi, K, Samejima, M, Fushinobu, S. | Deposit date: | 2006-12-01 | Release date: | 2007-03-27 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of intracellular family 1 beta-glucosidase BGL1A from the basidiomycete Phanerochaete chrysosporium Febs Lett., 581, 2007
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2EA9
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![BU of 2ea9 by Molmil](/molmil-images/mine/2ea9) | |
2E7Q
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![BU of 2e7q by Molmil](/molmil-images/mine/2e7q) | Crystal structure of basic winged bean lectin in complex with b blood group trisaccharide | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Basic agglutinin, CALCIUM ION, ... | Authors: | Kulkarni, K.A, Katiyar, S, Surolia, A, Vijayan, M, Suguna, K. | Deposit date: | 2007-01-12 | Release date: | 2007-06-19 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Generation of blood group specificity: New insights from structural studies on the complexes of A- and B-reactive saccharides with basic winged bean agglutinin Proteins, 68, 2007
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2EAU
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![BU of 2eau by Molmil](/molmil-images/mine/2eau) | Crystal structure of the SR CA2+-ATPASE with bound CPA in the presence of curcumin | Descriptor: | (6AR,11AS,11BR)-10-ACETYL-9-HYDROXY-7,7-DIMETHYL-2,6,6A,7,11A,11B-HEXAHYDRO-11H-PYRROLO[1',2':2,3]ISOINDOLO[4,5,6-CD]INDOL-11-ONE, PHOSPHATIDYLETHANOLAMINE, Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | Authors: | Takahashi, M, Kondou, Y, Toyoshima, C. | Deposit date: | 2007-02-02 | Release date: | 2007-03-27 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Interdomain communication in calcium pump as revealed in the crystal structures with transmembrane inhibitors Proc.Natl.Acad.Sci.Usa, 104, 2007
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2E88
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![BU of 2e88 by Molmil](/molmil-images/mine/2e88) | Crystal structure of the human Hsp70 ATPase domain in the apo form | Descriptor: | Heat shock 70kDa protein 1A, ZINC ION | Authors: | Shida, M, Ishii, R, Takagi, T, Kishishita, S, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-01-19 | Release date: | 2008-01-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Direct inter-subdomain interactions switch between the closed and open forms of the Hsp70 nucleotide-binding domain in the nucleotide-free state. Acta Crystallogr.,Sect.D, 66, 2010
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2EEV
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![BU of 2eev by Molmil](/molmil-images/mine/2eev) | Guanine riboswitch U22C, A52G mutant bound to hypoxanthine | Descriptor: | ACETATE ION, COBALT HEXAMMINE(III), HYPOXANTHINE, ... | Authors: | Gilbert, S.D, Love, C.E, Batey, R.T. | Deposit date: | 2007-02-19 | Release date: | 2007-11-13 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Mutational analysis of the purine riboswitch aptamer domain Biochemistry, 46, 2007
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2EG2
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![BU of 2eg2 by Molmil](/molmil-images/mine/2eg2) | The crystal structure of PII protein | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, Nitrogen regulatory protein P-II | Authors: | Sakai, H, Shinkai, A, Kitamura, Y, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-02-27 | Release date: | 2008-03-04 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | The crystal structure of PII protein To be Published
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2ECE
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2EF9
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![BU of 2ef9 by Molmil](/molmil-images/mine/2ef9) | Structural and mechanistic changes along an engineered path from metallo to non-metallo KDO8P synthase | Descriptor: | 2-dehydro-3-deoxyphosphooctonate aldolase, ARABINOSE-5-PHOSPHATE, PHOSPHOENOLPYRUVATE | Authors: | Kona, F, Xu, X, Martin, P, Kuzmic, P, Gatti, D.L. | Deposit date: | 2007-02-22 | Release date: | 2007-04-24 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and Mechanistic Changes along an Engineered Path from Metallo to Nonmetallo 3-Deoxy-d-manno-octulosonate 8-Phosphate Synthases Biochemistry, 46, 2007
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2E7Y
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![BU of 2e7y by Molmil](/molmil-images/mine/2e7y) | High resolution structure of T. maritima tRNase Z | Descriptor: | S-1,2-PROPANEDIOL, SULFATE ION, ZINC ION, ... | Authors: | Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-01-15 | Release date: | 2007-09-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | The structure of the flexible arm of Thermotoga maritima tRNase Z differs from those of homologous enzymes Acta Crystallogr.,Sect.F, 63, 2007
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