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7K43
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BU of 7k43 by Molmil
SARS-CoV-2 spike in complex with the S2M11 neutralizing antibody Fab fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S2M11 Fab fragment (heavy chain), ...
Authors:Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2020-09-14
Release date:2020-10-07
Last modified:2021-01-27
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms.
Science, 370, 2020
7EAM
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BU of 7eam by Molmil
immune complex of SARS-CoV-2 RBD and cross-neutralizing antibody 7D6
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, ...
Authors:Li, T.T, Gu, Y, Li, S.W.
Deposit date:2021-03-07
Release date:2021-03-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Cross-neutralizing antibodies bind a SARS-CoV-2 cryptic site and resist circulating variants.
Nat Commun, 12, 2021
7WS8
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BU of 7ws8 by Molmil
Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ...
Authors:Guo, H, Gao, Y, Ji, X, Yang, H.
Deposit date:2022-01-28
Release date:2022-06-01
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structures of Omicron spike complexes and implications for neutralizing antibody development.
Cell Rep, 39, 2022
7WS6
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BU of 7ws6 by Molmil
Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development
Descriptor: 510A5 heavy chain, 510A5 light chain, Spike protein S1
Authors:Guo, H, Gao, Y, Ji, X, Yang, H.
Deposit date:2022-01-28
Release date:2022-06-01
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structures of Omicron spike complexes and implications for neutralizing antibody development.
Cell Rep, 39, 2022
7WSA
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BU of 7wsa by Molmil
Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike protein S1
Authors:Guo, H, Gao, Y, Ji, X, Yang, H.
Deposit date:2022-01-28
Release date:2022-06-01
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structures of Omicron spike complexes and implications for neutralizing antibody development.
Cell Rep, 39, 2022
7WS9
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BU of 7ws9 by Molmil
Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ...
Authors:Guo, H, Gao, Y, Ji, X, Yang, H.
Deposit date:2022-01-28
Release date:2022-06-01
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structures of Omicron spike complexes and implications for neutralizing antibody development.
Cell Rep, 39, 2022
1ZVY
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BU of 1zvy by Molmil
Crystal structure of the VHH D3-L11 in complex with hen egg white lysozyme
Descriptor: GLYCEROL, Immunoglobulin heavy chain antibody variable domain, Lysozyme C, ...
Authors:De Genst, E, Silence, K, Decanniere, K, Conrath, K, Loris, R, Kinne, J, Muyldermans, S, Wyns, L.
Deposit date:2005-06-03
Release date:2006-04-04
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies.
Proc.Natl.Acad.Sci.Usa, 103, 2006
1RZG
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BU of 1rzg by Molmil
Crystal structure of Human anti-HIV-1 GP120 reactive antibody 412d
Descriptor: ASPARTIC ACID, CYSTEINE, Fab 412d heavy chain, ...
Authors:Huang, C.C, Venturi, M, Majeed, S, Moore, M.J, Phogat, S, Zhang, M.-Y, Dimitrov, D.S, Hendrickson, W.A, Robinson, J, Sodroski, J, Wyatt, R, Choe, H, Farzan, M, Kwong, P.D.
Deposit date:2003-12-24
Release date:2004-02-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120
Proc.Natl.Acad.Sci.USA, 101, 2004
1RZ7
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BU of 1rz7 by Molmil
CRYSTAL STRUCTURE OF HUMAN ANTI-HIV-1 GP120-REACTIVE ANTIBODY 48D
Descriptor: Fab 48d heavy chain, Fab 48d light chain, GLYCEROL
Authors:Huang, C.C, Venturi, M, Majeed, S, Moore, M.J, Phogat, S, Zhang, M.-Y, Dimitrov, D.S, Hendrickson, W.A, Robinson, J, Sodroski, J, Wyatt, R, Choe, H, Farzan, M, Kwong, P.D.
Deposit date:2003-12-24
Release date:2004-02-03
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120
Proc.Natl.Acad.Sci.USA, 101, 2004
1RZI
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BU of 1rzi by Molmil
Crystal structure of human anti-HIV-1 gp120-reactive antibody 47e fab
Descriptor: Fab 47e heavy chain, Fab 47e light chain
Authors:Huang, C.C, Venturi, M, Majeed, S, Moore, M.J, Phogat, S, Zhang, M.-Y, Dimitrov, D.S, Hendrickson, W.A, Robinson, J, Sodroski, J, Wyatt, R, Choe, H, Farzan, M, Kwong, P.D.
Deposit date:2003-12-24
Release date:2004-02-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120
Proc.Natl.Acad.Sci.USA, 101, 2004
4KPH
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BU of 4kph by Molmil
Structure of the Fab fragment of N62, a protective monoclonal antibody to the nonreducing end of Francisella tularensis O-antigen
Descriptor: ACETATE ION, N62 heavy chain, N62 light chain
Authors:Lu, Z, Rynkiewicz, M.J, Yang, C.-Y, Madico, G, Perkins, H.M, Wang, Q, Costello, C.E, Zaia, J, Seaton, B.A, Sharon, J.
Deposit date:2013-05-13
Release date:2013-07-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:The binding sites of monoclonal antibodies to the non-reducing end of Francisella tularensis O-antigen accommodate mainly the terminal saccharide.
Immunology, 140, 2013
1RZF
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BU of 1rzf by Molmil
Crystal structure of Human anti-HIV-1 GP120-reactive antibody E51
Descriptor: Fab E51 heavy chain, Fab E51 light chain, GLYCEROL, ...
Authors:Huang, C.C, Venturi, M, Majeed, S, Moore, M.J, Phogat, S, Zhang, M.-Y, Dimitrov, D.S, Hendrickson, W.A, Robinson, J, Sodroski, J, Wyatt, R, Choe, H, Farzan, M, Kwong, P.D.
Deposit date:2003-12-24
Release date:2004-02-03
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120
Proc.Natl.Acad.Sci.USA, 101, 2004
7KET
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BU of 7ket by Molmil
Factor H enhancing human antibody fragment (Fab) to meningococcal Factor H binding protein
Descriptor: Factor H binding protein, Immunoglobulin gamma, heavy chain Fd fragment, ...
Authors:Beernink, P.T, Sands, N.
Deposit date:2020-10-12
Release date:2021-06-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Two human antibodies to a meningococcal serogroup B vaccine antigen enhance binding of complement Factor H by stabilizing the Factor H binding site.
Plos Pathog., 17, 2021
7KE1
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BU of 7ke1 by Molmil
Factor H enhancing human antibody fragment (Fab) to meningococcal Factor H binding protein
Descriptor: CHLORIDE ION, Immunoglobulin gamma, heavy chain Fd fragment, ...
Authors:Beernink, P.T, Sands, N.
Deposit date:2020-10-09
Release date:2021-06-09
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Two human antibodies to a meningococcal serogroup B vaccine antigen enhance binding of complement Factor H by stabilizing the Factor H binding site.
Plos Pathog., 17, 2021
1RZ8
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BU of 1rz8 by Molmil
CRYSTAL STRUCTURE OF HUMAN ANTI-HIV-1 GP120-REACTIVE ANTIBODY 17B
Descriptor: Fab 17b heavy chain, Fab 17b light chain
Authors:Huang, C.C, Venturi, M, Majeed, S, Moore, M.J, Phogat, S, Zhang, M.-Y, Dimitrov, D.S, Hendrickson, W.A, Robinson, J, Sodroski, J, Wyatt, R, Choe, H, Farzan, M, Kwong, P.D.
Deposit date:2003-12-24
Release date:2004-02-03
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120
Proc.Natl.Acad.Sci.USA, 101, 2004
7WG3
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BU of 7wg3 by Molmil
Structural basis of interleukin-17B receptor in complex with a neutralizing antibody D9 for guiding humanization and affinity maturation for cancer therapy
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of D9 Fab, IL17RB protein, ...
Authors:Lee, W.H, Chen, X.R, Liu, I.J, Lee, J.H, Hu, C.M, Wu, H.C, Wang, S.K, Lee, W.H, Ma, C.
Deposit date:2021-12-28
Release date:2022-11-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Structural basis of interleukin-17B receptor in complex with a neutralizing antibody for guiding humanization and affinity maturation.
Cell Rep, 41, 2022
7F12
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BU of 7f12 by Molmil
A SARS-CoV-2 neutralizing antibody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody, Spike protein S1
Authors:Zhang, G, Li, X, Guo, Y, Wang, Y, Yuan, S.
Deposit date:2021-06-07
Release date:2022-06-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:A SARS-CoV-2 neutralizing antibody
To Be Published
7F15
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BU of 7f15 by Molmil
A SARS-CoV-2 neutralizing antibody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody, Spike protein S1
Authors:Zhang, G, Li, X, Guo, Y, Wang, Y, Yuan, S.
Deposit date:2021-06-07
Release date:2022-06-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:A SARS-CoV-2 neutralizing antibody
To Be Published
7LL2
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BU of 7ll2 by Molmil
Cryo-EM structure of BG505 DS-SOSIP in complex with Glycan276-Dependent Broadly Neutralizing Antibody VRC33.01 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ...
Authors:Manne, K, Acharya, P.
Deposit date:2021-02-03
Release date:2021-03-17
Last modified:2021-11-17
Method:ELECTRON MICROSCOPY (3.73 Å)
Cite:Structural basis of glycan276-dependent recognition by HIV-1 broadly neutralizing antibodies.
Cell Rep, 37, 2021
7LS9
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BU of 7ls9 by Molmil
Cryo-EM structure of neutralizing antibody 1-57 in complex with prefusion SARS-CoV-2 spike glycoprotein
Descriptor: 1-57 Fab heavy chain, 1-57 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Cerutti, G, Shapiro, L.
Deposit date:2021-02-17
Release date:2021-03-17
Last modified:2021-09-29
Method:ELECTRON MICROSCOPY (3.42 Å)
Cite:Structural basis for accommodation of emerging B.1.351 and B.1.1.7 variants by two potent SARS-CoV-2 neutralizing antibodies.
Structure, 29, 2021
7LLK
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BU of 7llk by Molmil
Cryo-EM structure of Q23.17_DS-SOSIP in complex with Glycan276-Dependent Broadly Neutralizing Antibody 179NC75 Fab
Descriptor: 179NC75 Fab Heavy chain, 179NC75 Fab Light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Manne, K, Acharya, P.
Deposit date:2021-02-04
Release date:2021-06-02
Last modified:2021-11-17
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Structural basis of glycan276-dependent recognition by HIV-1 broadly neutralizing antibodies.
Cell Rep, 37, 2021
8DG8
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BU of 8dg8 by Molmil
Cryo-EM Structure of HPIV3 prefusion F trimer in complex with 3x1 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3x1 monoclonal antibody, VH region, ...
Authors:Rodarte, J.V, Pancera, M.
Deposit date:2022-06-23
Release date:2023-02-22
Method:ELECTRON MICROSCOPY (3.62 Å)
Cite:Cross-protective antibodies against common endemic respiratory viruses.
Nat Commun, 14, 2023
7R7N
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BU of 7r7n by Molmil
SARS-CoV-2 spike in complex with the S2D106 neutralizing antibody Fab fragment (local refinement of the RBD and S2D106)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, S2D106 FAB heavy chain, S2D106 FAB light chain, ...
Authors:Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2021-06-25
Release date:2021-07-21
Last modified:2021-09-15
Method:ELECTRON MICROSCOPY (3.95 Å)
Cite:SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape.
Nature, 597, 2021
7Y6K
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BU of 7y6k by Molmil
Cryo-EM structure of SARS-CoV-2 receptor binding domain in complex with K202.B bispecific antibody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab region of heavy chain from K202.B, bispecific antibody, ...
Authors:Yoo, Y, Cho, H.S.
Deposit date:2022-06-20
Release date:2023-07-19
Method:ELECTRON MICROSCOPY (3.34 Å)
Cite:Cryo-EM structure of SARS-CoV-2 receptor binding domain in complex with K202.B bispecific antibody
To Be Published
7UTV
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BU of 7utv by Molmil
CPV Total-Fab Polyclonal B Site Fab (2 of 2)
Descriptor: Capsid protein VP1, Heavy chain antibody fragment, Light chain antibody fragment
Authors:Hartmann, S.R, Hafenstein, S.L, Charnesky, A.J.
Deposit date:2022-04-27
Release date:2023-10-04
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Cryo EM structures map a post vaccination polyclonal antibody response to canine parvovirus.
Commun Biol, 6, 2023

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数据于2024-07-24公开中

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