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2O72
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BU of 2o72 by Molmil
Crystal Structure Analysis of human E-cadherin (1-213)
Descriptor: CALCIUM ION, Epithelial-cadherin
Authors:Parisini, E, Wang, J.-H.
Deposit date:2006-12-09
Release date:2007-10-09
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Crystal Structure of Human E-cadherin Domains 1 and 2, and Comparison with other Cadherins in the Context of Adhesion Mechanism
J.Mol.Biol., 373, 2007
5NO6
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BU of 5no6 by Molmil
TEAD4-HOXB13 complex bound to DNA
Descriptor: DNA, Homeobox protein Hox-B13, Transcriptional enhancer factor TEF-3
Authors:Morgunova, E, Jolma, A, Yin, Y, Popov, A, Taipale, J.
Deposit date:2017-04-11
Release date:2018-05-16
Last modified:2025-04-23
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:DNA-guided transcription factor interactions extend human gene regulatory code.
Nature, 2025
1MBB
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BU of 1mbb by Molmil
OXIDOREDUCTASE
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, URIDINE DIPHOSPHO-N-ACETYLENOLPYRUVYLGLUCOSAMINE REDUCTASE, URIDINE-DIPHOSPHATE-3(N-ACETYLGLUCOSAMINYL)BUTYRIC ACID
Authors:Benson, T.E, Lees, W.J, Walsh, C.T, Hogle, J.M.
Deposit date:1995-11-07
Release date:1996-10-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:(E)-enolbutyryl-UDP-N-acetylglucosamine as a mechanistic probe of UDP-N-acetylenolpyruvylglucosamine reductase (MurB).
Biochemistry, 35, 1996
4ZSW
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BU of 4zsw by Molmil
Pig Brain GABA-AT inactivated by (E)-(1S,3S)-3-Amino-4-fluoromethylenyl-1-cyclopentanoic acid
Descriptor: (1S)-4-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]cyclopent-3-ene-1,3-dicarboxylic acid, 4-aminobutyrate aminotransferase, mitochondrial, ...
Authors:Wu, R, Lee, H, Le, H.V, Doud, E, Sanishvili, R, Compton, P, Kelleher, N.L, Silverman, R.B, Liu, D.
Deposit date:2015-05-14
Release date:2015-07-08
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Mechanism of Inactivation of GABA Aminotransferase by (E)- and (Z)-(1S,3S)-3-Amino-4-fluoromethylenyl-1-cyclopentanoic Acid.
Acs Chem.Biol., 10, 2015
5AAU
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BU of 5aau by Molmil
Optimization of a novel binding motif to to (E)-3-(3,5-difluoro-4-((1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro-1H- pyrido(3,4-b)indol-1-yl)phenyl)acrylic acid (AZD9496), a potent and orally bioavailable selective estrogen receptor downregulator and antagonist
Descriptor: 3-(1-(4-Chlorophenyl)-3,4-dihydro-1H-pyrido(3,4-b)indol-2(9H)-yl)propanoic acid, ESTROGEN RECEPTOR
Authors:Norman, R.A, Bradbury, R.H, de Almeida, C, Andrews, D.M, Ballard, P, Buttar, D, Callis, R.J, Currie, G.S, Curwen, J.O, Davies, C.D, de Savi, C, Donald, C.S, Feron, L.J.L, Glossop, S.C, Hayter, B.R, Karoutchi, G, Lamont, S.G, MacFaul, P, Moss, T, Pearson, S.E, Rabow, A.A, Tonge, M, Walker, G.E, Weir, H.M, Wilson, Z.
Deposit date:2015-07-28
Release date:2015-10-14
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Optimization of a Novel Binding Motif to (E)-3-(3,5-Difluoro-4-((1R,3R)-2-(2-Fluoro-2-Methylpropyl)-3-Methyl-2, 3,4,9-Tetrahydro-1H-Pyrido[3,4-B]Indol-1-Yl)Phenyl)Acrylic Acid (Azd9496), a Potent and Orally Bioavailable Selective Estrogen Receptor Downregulator and Antagonist.
J.Med.Chem., 58, 2015
5AAV
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BU of 5aav by Molmil
Optimization of a novel binding motif to to (E)-3-(3,5-difluoro-4-((1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro-1H- pyrido(3,4-b)indol-1-yl)phenyl)acrylic acid (AZD9496), a potent and orally bioavailable selective estrogen receptor downregulator and antagonist
Descriptor: (2E)-3-{4-[(1E)-1,2-DIPHENYLBUT-1-ENYL]PHENYL}ACRYLIC ACID, ESTROGEN RECEPTOR
Authors:Norman, R.A, Bradbury, R.H, de Almeida, C, Andrews, D.M, Ballard, P, Buttar, D, Callis, R.J, Currie, G.S, Curwen, J.O, Davies, C.D, de Savi, C, Donald, C.S, Feron, L.J.L, Glossop, S.C, Hayter, B.R, Karoutchi, G, Lamont, S.G, MacFaul, P, Moss, T, Pearson, S.E, Rabow, A.A, Tonge, M, Walker, G.E, Weir, H.M, Wilson, Z.
Deposit date:2015-07-29
Release date:2015-10-14
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Optimization of a Novel Binding Motif to (E)-3-(3,5-Difluoro-4-((1R,3R)-2-(2-Fluoro-2-Methylpropyl)-3-Methyl-2, 3,4,9-Tetrahydro-1H-Pyrido[3,4-B]Indol-1-Yl)Phenyl)Acrylic Acid (Azd9496), a Potent and Orally Bioavailable Selective Estrogen Receptor Downregulator and Antagonist.
J.Med.Chem., 58, 2015
7YG6
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BU of 7yg6 by Molmil
Cryo-EM structure of the EfPiwi(N959K) in complex with piRNA
Descriptor: MAGNESIUM ION, Piwi, piRNA
Authors:Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z.
Deposit date:2022-07-11
Release date:2024-01-24
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing.
Nat.Struct.Mol.Biol., 2024
7YFX
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BU of 7yfx by Molmil
Cryo-EM structure of Hili in complex with piRNA
Descriptor: MAGNESIUM ION, Piwi-like protein 2, piRNA
Authors:Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z.
Deposit date:2022-07-09
Release date:2024-01-24
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing.
Nat.Struct.Mol.Biol., 2024
7YGN
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BU of 7ygn by Molmil
Cryo-EM structure of the Mili in complex with piRNA
Descriptor: MAGNESIUM ION, Piwi-like protein 2, piRNA
Authors:Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z.
Deposit date:2022-07-11
Release date:2024-01-24
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing.
Nat.Struct.Mol.Biol., 2024
9IJ0
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BU of 9ij0 by Molmil
Cryo-EM Structure of MILI-piRNA-target (8-nt)
Descriptor: MAGNESIUM ION, Piwi-like protein 2, RNA (26-MER), ...
Authors:Li, Z.Q, Xu, Q.K, Wu, J.P, Shen, E.Z.
Deposit date:2024-06-21
Release date:2024-11-13
Last modified:2025-03-19
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural insights into RNA cleavage by PIWI Argonaute.
Nature, 639, 2025
1EZZ
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BU of 1ezz by Molmil
CRYSTAL STRUCTURE OF E. COLI ASPARTATE TRANSCARBAMOYLASE P268A MUTANT IN THE T-STATE
Descriptor: ASPARTATE CARBAMOYLTRANSFERASE CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ZINC ION
Authors:Jin, L, Stec, B, Kantrowitz, E.R.
Deposit date:2000-05-12
Release date:2000-11-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A cis-proline to alanine mutant of E. coli aspartate transcarbamoylase: kinetic studies and three-dimensional crystal structures.
Biochemistry, 39, 2000
6HPB
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BU of 6hpb by Molmil
Crystal structure of the E.coli HicAB toxin-antitoxin complex
Descriptor: Antitoxin HicB, SULFATE ION, mRNA interferase toxin HicA
Authors:Manav, M.C, Brodersen, D.E.
Deposit date:2018-09-20
Release date:2019-09-18
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:The E. coli HicB Antitoxin Contains a Structurally Stable Helix-Turn-Helix DNA Binding Domain.
Structure, 27, 2019
4C16
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BU of 4c16 by Molmil
E-selectin lectin, EGF-like and two SCR domains complexed with glycomimetic antagonist
Descriptor: (1R,2R,3S)-3-methylcyclohexane-1,2-diol, (S)-CYCLOHEXYL LACTIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Preston, R.C, Jakob, R.P, Binder, F.P.C, Sager, C.P, Ernst, B, Maier, T.
Deposit date:2013-08-09
Release date:2014-08-20
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:E-Selectin Ligand Complexes Adopt an Extended High-Affinity Conformation.
J.Mol.Cell.Biol., 8, 2016
1F1B
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BU of 1f1b by Molmil
CRYSTAL STRUCTURE OF E. COLI ASPARTATE TRANSCARBAMOYLASE P268A MUTANT IN THE R-STATE IN THE PRESENCE OF N-PHOSPHONACETYL-L-ASPARTATE
Descriptor: ASPARTATE CARBAMOYLTRANSFERASE CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, N-(PHOSPHONACETYL)-L-ASPARTIC ACID, ...
Authors:Jin, L, Stec, B, Kantrowitz, E.R.
Deposit date:2000-05-18
Release date:2000-11-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A cis-proline to alanine mutant of E. coli aspartate transcarbamoylase: kinetic studies and three-dimensional crystal structures.
Biochemistry, 39, 2000
4L1T
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BU of 4l1t by Molmil
Transthyretin in complex with (E)-3-(dimethylamino)-5-(4-hydroxy-3,5-dimethylstyryl)benzoic acid
Descriptor: 3-(dimethylamino)-5-[(E)-2-(4-hydroxy-3,5-dimethylphenyl)ethenyl]benzoic acid, Transthyretin
Authors:Connelly, S, Wilson, I.A.
Deposit date:2013-06-03
Release date:2013-10-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.16 Å)
Cite:Fluorogenic small molecules requiring reaction with a specific protein to create a fluorescent conjugate for biological imaging-what we know and what we need to learn.
Biopolymers, 101, 2014
4HR7
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BU of 4hr7 by Molmil
Crystal Structure of Biotin Carboxyl Carrier Protein-Biotin Carboxylase Complex from E.coli
Descriptor: 1,2-ETHANEDIOL, Biotin carboxyl carrier protein of acetyl-CoA carboxylase, Biotin carboxylase, ...
Authors:Broussard, T.C, Kobe, M.J, Pakhomova, S, Neau, D.B, Price, A.E, Champion, T.S, Waldrop, G.L.
Deposit date:2012-10-26
Release date:2013-03-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.495 Å)
Cite:The three-dimensional structure of the biotin carboxylase-biotin carboxyl carrier protein complex of E. coli acetyl-CoA carboxylase.
Structure, 21, 2013
7DFM
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BU of 7dfm by Molmil
Crystal structure of glycoside hydrolase family 11 beta-xylanase from Streptomyces olivaceoviridis E-86
Descriptor: CHLORIDE ION, Endo-1,4-beta-xylanase
Authors:Fujimoto, Z, Kishine, N, Kaneko, S.
Deposit date:2020-11-09
Release date:2020-12-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure-based substrate specificity analysis of GH11 xylanase from Streptomyces olivaceoviridis E-86.
Appl.Microbiol.Biotechnol., 105, 2021
7DFO
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BU of 7dfo by Molmil
Crystal structure of glycoside hydrolase family 11 beta-xylanase from Streptomyces olivaceoviridis E-86 in complex with 4-O-methyl-alpha-D-glucuronopyranosyl xylotetraose
Descriptor: 4-O-methyl-alpha-D-glucopyranuronic acid-(1-2)-[beta-D-xylopyranose-(1-4)]beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose, 4-O-methyl-alpha-D-glucopyranuronic acid-(1-2)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose, CHLORIDE ION, ...
Authors:Fujimoto, Z, Kishine, N, Kaneko, S.
Deposit date:2020-11-09
Release date:2020-12-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-based substrate specificity analysis of GH11 xylanase from Streptomyces olivaceoviridis E-86.
Appl.Microbiol.Biotechnol., 105, 2021
3MPB
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BU of 3mpb by Molmil
Z5688 from E. coli O157:H7 bound to fructose
Descriptor: ACETATE ION, GLYCEROL, MANGANESE (II) ION, ...
Authors:van Staalduinen, L.M, Jia, Z, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2010-04-26
Release date:2010-07-21
Last modified:2024-11-27
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Structure-based annotation of a novel sugar isomerase from the pathogenic E. coli O157:H7.
J.Mol.Biol., 401, 2010
3KMH
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BU of 3kmh by Molmil
Crystal Structure of a Novel Sugar Isomerase from E. coli O157:H7
Descriptor: ACETATE ION, D-lyxose isomerase, GLYCEROL, ...
Authors:van Staalduinen, L.M, Jia, Z, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2009-11-10
Release date:2010-07-21
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Structure-based annotation of a novel sugar isomerase from the pathogenic E. coli O157:H7.
J.Mol.Biol., 401, 2010
7JGJ
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BU of 7jgj by Molmil
IgA1 Protease in complex with neutralizing mAb
Descriptor: Immunoglobulin A1 protease, mAB Heavy Chain, mAB Light Chain
Authors:Eisenmesser, E.Z, Zheng, H.
Deposit date:2020-07-19
Release date:2020-12-09
Last modified:2025-05-28
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Mechanism and inhibition of Streptococcus pneumoniae IgA1 protease
Nat Commun, 11, 2020
3TTQ
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BU of 3ttq by Molmil
Crystal structure of Leuconostoc mesenteroides NRRL B-1299 N-terminally truncated dextransucrase DSR-E in orthorhombic apo-form at 1.9 angstrom resolution
Descriptor: CALCIUM ION, Dextransucrase, GLYCEROL, ...
Authors:Brison, Y, Pijning, T, Fabre, E, Mourey, L, Morel, S, Potocki-Veronese, G, Monsan, P, Remaud-Simeon, M, Dijkstra, B.W, Tranier, S.
Deposit date:2011-09-15
Release date:2012-01-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Functional and structural characterization of alpha-(1-2) branching sucrase derived from DSR-E glucansucrase
J.Biol.Chem., 287, 2012
1V6V
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BU of 1v6v by Molmil
Crystal Structure Of Xylanase From Streptomyces Olivaceoviridis E-86 Complexed With 3(2)-alpha-L-arabinofuranosyl-xylotriose
Descriptor: ENDO-1,4-BETA-D-XYLANASE, alpha-L-arabinofuranose-(1-3)-[beta-D-xylopyranose-(1-4)]beta-D-xylopyranose-(1-4)-beta-D-xylopyranose, beta-D-xylopyranose, ...
Authors:Fujimoto, Z, Kaneko, S, Kuno, A, Kobayashi, H, Kusakabe, I, Mizuno, H.
Deposit date:2003-12-04
Release date:2004-04-27
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of decorated xylooligosaccharides bound to a family 10 xylanase from Streptomyces olivaceoviridis E-86
J.Biol.Chem., 279, 2004
1V6X
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BU of 1v6x by Molmil
Crystal Structure Of Xylanase From Streptomyces Olivaceoviridis E-86 Complexed With 3(3)-4-O-methyl-alpha-D-glucuronosyl-xylotriose
Descriptor: 4-O-methyl-alpha-D-glucopyranuronic acid-(1-2)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose, ENDO-1,4-BETA-D-XYLANASE, beta-D-xylopyranose, ...
Authors:Fujimoto, Z, Kaneko, S, Kuno, A, Kobayashi, H, Kusakabe, I, Mizuno, H.
Deposit date:2003-12-04
Release date:2004-04-27
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of decorated xylooligosaccharides bound to a family 10 xylanase from Streptomyces olivaceoviridis E-86
J.Biol.Chem., 279, 2004
1V6U
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BU of 1v6u by Molmil
Crystal Structure Of Xylanase From Streptomyces Olivaceoviridis E-86 Complexed With 2(2)-alpha-L-arabinofuranosyl-xylobiose
Descriptor: alpha-D-xylopyranose, alpha-L-arabinofuranose-(1-3)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose, beta-D-xylopyranose, ...
Authors:Fujimoto, Z, Kaneko, S, Kuno, A, Kobayashi, H, Kusakabe, I, Mizuno, H.
Deposit date:2003-12-04
Release date:2004-04-27
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of decorated xylooligosaccharides bound to a family 10 xylanase from Streptomyces olivaceoviridis E-86
J.Biol.Chem., 279, 2004

238582

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