PDB: 5793 resultsInfo pagesStatus searchChemie searchBIRD

---

7OSV	DeNovoTIM6-SB, a de novo designed TIM barrel with a salt-bridge cluster (crystal form 1) Descriptor: ACETATE ION, DI(HYDROXYETHYL)ETHER, DeNovoTIM6-SB, ... Authors: Kordes, S, Romero-Romero, S, Hocker, B. Deposit date: 2021-06-09 Release date: 2021-12-15 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.66 Å) Cite: A newly introduced salt bridge cluster improves structural and biophysical properties of de novo TIM barrels. Protein Sci., 31, 2022
7P12	DeNovoTIM13-SB, a de novo designed TIM barrel with a salt-bridge cluster Descriptor: CHLORIDE ION, DeNovoTIM13-SB, PHOSPHATE ION Authors: Kordes, S, Romero-Romero, S, Hocker, B. Deposit date: 2021-07-01 Release date: 2021-12-15 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.69 Å) Cite: A newly introduced salt bridge cluster improves structural and biophysical properties of de novo TIM barrels. Protein Sci., 31, 2022
7OT8	DeNovoTIM6-SB, a de novo designed TIM barrel with a salt-bridge cluster (crystal form 2) Descriptor: DeNovoTIM6-SB, SULFATE ION Authors: Kordes, S, Romero-Romero, S, Hocker, B. Deposit date: 2021-06-09 Release date: 2021-12-15 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.22 Å) Cite: A newly introduced salt bridge cluster improves structural and biophysical properties of de novo TIM barrels. Protein Sci., 31, 2022
7OSU	sTIM11noCys-SB, a de novo designed TIM barrel with a salt-bridge cluster (crystal form 1) Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... Authors: Romero-Romero, S, Kordes, S, Hocker, B. Deposit date: 2021-06-09 Release date: 2021-12-15 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.37 Å) Cite: A newly introduced salt bridge cluster improves structural and biophysical properties of de novo TIM barrels. Protein Sci., 31, 2022
7OT7	sTIM11noCys-SB, a de novo designed TIM barrel with a salt-bridge cluster (crystal form 2) Descriptor: sTIM11noCys-SB Authors: Romero-Romero, S, Kordes, S, Hocker, B. Deposit date: 2021-06-09 Release date: 2021-12-15 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.51 Å) Cite: A newly introduced salt bridge cluster improves structural and biophysical properties of de novo TIM barrels. Protein Sci., 31, 2022
5TX8	Solution structure of the de novo mini protein gHH_44 Descriptor: HH2 Authors: Buchko, G.W, Bahl, C.D, Baker, D. Deposit date: 2016-11-15 Release date: 2017-09-27 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Cytosolic expression, solution structures, and molecular dynamics simulation of genetically encodable disulfide-rich de novo designed peptides. Protein Sci., 27, 2018
6W70	Crystal Structure of apixaban-bound ABLE Descriptor: 1-(4-METHOXYPHENYL)-7-OXO-6-[4-(2-OXOPIPERIDIN-1-YL)PHENYL]-4,5,6,7-TETRAHYDRO-1H-PYRAZOLO[3,4-C]PYRIDINE-3-CARBOXAMIDE, ACETATE ION, De novo designed ABLE, ... Authors: Polizzi, N.F. Deposit date: 2020-03-18 Release date: 2020-08-26 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.296 Å) Cite: A defined structural unit enables de novo design of small-molecule-binding proteins. Science, 369, 2020
3V1A	Crystal structure of de novo designed MID1-apo1 Descriptor: Computational design, MID1-apo1 Authors: Der, B.S, Machius, M, Miley, M.J, Kuhlman, B. Deposit date: 2011-12-09 Release date: 2012-01-11 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (0.98 Å) Cite: Metal-mediated affinity and orientation specificity in a computationally designed protein homodimer. J.Am.Chem.Soc., 134, 2012
3V1E	Crystal structure of de novo designed MID1-zinc H12E mutant Descriptor: Computational design, MID1-zinc H12E mutant, ZINC ION Authors: Der, B.S, Machius, M, Miley, M.J, Kuhlman, B. Deposit date: 2011-12-09 Release date: 2012-01-11 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.073 Å) Cite: Metal-mediated affinity and orientation specificity in a computationally designed protein homodimer. J.Am.Chem.Soc., 134, 2012
3V1C	Crystal structure of de novo designed MID1-zinc Descriptor: Computational design, MID1-zinc, L(+)-TARTARIC ACID, ... Authors: Der, B.S, Machius, M, Miley, M.J, Kuhlman, B. Deposit date: 2011-12-09 Release date: 2012-01-11 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.129 Å) Cite: Metal-mediated affinity and orientation specificity in a computationally designed protein homodimer. J.Am.Chem.Soc., 134, 2012
3V1F	Crystal structure of de novo designed MID1-zinc H35E mutant Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Computational design, ... Authors: Der, B.S, Machius, M, Miley, M.J, Kuhlman, B. Deposit date: 2011-12-09 Release date: 2012-01-11 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.151 Å) Cite: Metal-mediated affinity and orientation specificity in a computationally designed protein homodimer. J.Am.Chem.Soc., 134, 2012
3V1D	Crystal structure of de novo designed MID1-cobalt Descriptor: COBALT (II) ION, Computational design, MID1-cobalt, ... Authors: Der, B.S, Machius, M, Miley, M.J, Kuhlman, B. Deposit date: 2011-12-09 Release date: 2012-01-11 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.239 Å) Cite: Metal-mediated affinity and orientation specificity in a computationally designed protein homodimer. J.Am.Chem.Soc., 134, 2012
3V1B	Crystal structure of de novo designed MID1-apo2 Descriptor: Computational design, MID1-apo2, GLYCEROL Authors: Der, B.S, Machius, M, Miley, M.J, Kuhlman, B. Deposit date: 2011-12-09 Release date: 2012-01-11 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.28 Å) Cite: Metal-mediated affinity and orientation specificity in a computationally designed protein homodimer. J.Am.Chem.Soc., 134, 2012
5EZA	A de novo designed heptameric coiled coil CC-Hept-I18C-L22H Descriptor: CC-Hept-C-H-I, GLYCEROL Authors: Burton, A.J, Brady, R.L, Woolfson, D.N. Deposit date: 2015-11-26 Release date: 2016-07-06 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.76 Å) Cite: Installing hydrolytic activity into a completely de novo protein framework. Nat.Chem., 8, 2016
5EZE	A de novo designed heptameric coiled coil CC-Hept-I18betaMeCys-L22H-I25E Descriptor: CC-Hept-bMeCys-His-Glu, GLYCEROL Authors: Burton, A.J, Brady, R.L, Woolfson, D.N. Deposit date: 2015-11-26 Release date: 2016-07-06 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Installing hydrolytic activity into a completely de novo protein framework. Nat.Chem., 8, 2016
5EZ9	A de novo designed heptameric coiled coil CC-Hept-I-H-I Descriptor: CC-Hept-L22H, HEXANE-1,6-DIOL Authors: Burton, A.J, Brady, R.L, Woolfson, D.N. Deposit date: 2015-11-26 Release date: 2016-07-06 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Installing hydrolytic activity into a completely de novo protein framework. Nat.Chem., 8, 2016
5EZC	A de novo designed heptameric coiled coil CC-Hept-I18C-L22H-I25E Descriptor: CC-Hept-C-H-E Authors: Burton, A.J, Brady, R.L, Woolfson, D.N. Deposit date: 2015-11-26 Release date: 2016-07-06 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Installing hydrolytic activity into a completely de novo protein framework. Nat.Chem., 8, 2016
5F2Y	A de novo designed heptameric coiled coil CC-Hept-homoCys-H-E Descriptor: CC-Hept-hCys-H-E Authors: Burton, A.J, Brady, R.L, Woolfson, D.N. Deposit date: 2015-12-02 Release date: 2016-07-06 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Installing hydrolytic activity into a completely de novo protein framework. Nat.Chem., 8, 2016
5EZ8	A de novo designed heptameric coiled coil CC-Hept-I-C-I Descriptor: CC-Hept-I-C-I Authors: Burton, A.J, Brady, R.L, Woolfson, D.N. Deposit date: 2015-11-26 Release date: 2016-07-06 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Installing hydrolytic activity into a completely de novo protein framework. Nat.Chem., 8, 2016
5EON	Crystal structure of a de novo antiparallel coiled-coil hexamer - ACC-Hex Descriptor: ACC-Hex Authors: Spencer, R.K, Hochbaum, A.I. Deposit date: 2015-11-10 Release date: 2016-05-25 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.696 Å) Cite: X-ray Crystallographic Structure and Solution Behavior of an Antiparallel Coiled-Coil Hexamer Formed by de Novo Peptides. Biochemistry, 55, 2016
5EHB	A de novo designed hexameric coiled-coil peptide with iodotyrosine Descriptor: pHiosYI Authors: Lizatovic, R, Aurelius, O, Stenstrom, O, Drakenberg, T, Akke, M, Logan, D.T, Andre, I. Deposit date: 2015-10-28 Release date: 2016-06-15 Last modified: 2018-01-17 Method: X-RAY DIFFRACTION (3.19 Å) Cite: A De Novo Designed Coiled-Coil Peptide with a Reversible pH-Induced Oligomerization Switch. Structure, 24, 2016
5JI4	Solution structure of the de novo mini protein gEEHE_02 Descriptor: W37 Authors: Buchko, G.W, Bahl, C.D, Pulavarti, S.V, Baker, D, Szyperski, T. Deposit date: 2016-04-21 Release date: 2016-09-28 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Accurate de novo design of hyperstable constrained peptides. Nature, 538, 2016
5JHI	Solution structure of the de novo mini protein gEHE_06 Descriptor: W35 Authors: Buchko, G.W, Bahl, C.D, Gilmore, J.M, Pulavarti, S.V, Baker, D, Szyperski, T. Deposit date: 2016-04-21 Release date: 2016-09-28 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Accurate de novo design of hyperstable constrained peptides. Nature, 538, 2016
6W6X	Crystal Structure of ABLE Apo-protein Descriptor: ACETATE ION, De novo designed ABLE protein, SULFATE ION Authors: Polizzi, N.F. Deposit date: 2020-03-18 Release date: 2020-08-26 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.297 Å) Cite: A defined structural unit enables de novo design of small-molecule-binding proteins. Science, 369, 2020
8FBO	Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains Descriptor: KWOCA_102 Authors: Wang, J.Y, Khmelinskaia, A, Bera, A.K, King, N.P. Deposit date: 2022-11-29 Release date: 2023-03-22 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (3.4 Å) Cite: Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains. Proc.Natl.Acad.Sci.USA, 120, 2023

<234567891011121314151617>