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4WRO
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BU of 4wro by Molmil
Complex of 70S ribosome with tRNA-Phe and mRNA with C-A mismatch in the second position in the A-site
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G.
Deposit date:2014-10-24
Release date:2015-06-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015
4WQR
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BU of 4wqr by Molmil
Complex of 70S ribosome with tRNA-Phe and mRNA with C-A mismatch in the first position in the A-site.
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G.
Deposit date:2014-10-22
Release date:2015-06-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015
4WM8
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BU of 4wm8 by Molmil
Crystal Structure of Human Enterovirus D68
Descriptor: DECANOIC ACID, VP1, VP2, ...
Authors:Liu, Y, Sheng, J, Fokine, A, Meng, G, Long, F, Kuhn, R.J, Rossmann, M.G.
Deposit date:2014-10-08
Release date:2015-01-14
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Virus structure. Structure and inhibition of EV-D68, a virus that causes respiratory illness in children.
Science, 347, 2015
4WQY
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BU of 4wqy by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with elongation factor G in the post-translocational state (without fusitic acid)
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Lin, J, Gagnon, M.G, Steitz, T.A.
Deposit date:2014-10-22
Release date:2015-01-28
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Conformational Changes of Elongation Factor G on the Ribosome during tRNA Translocation.
Cell, 160, 2015
4WR6
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BU of 4wr6 by Molmil
Complex of 70S ribosome with tRNA-Tyr and mRNA with A-A mismatch in the first position in the A-site.
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G.
Deposit date:2014-10-23
Release date:2015-06-10
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015
3T1A
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BU of 3t1a by Molmil
Crystal Structure of HIV-1 Reverse Transcriptase (K103N mutant) in Complex with Inhibitor M05
Descriptor: 1-(2,5-dichloro-3-{[5-chloro-1-(2H-pyrazolo[3,4-b]pyridin-3-ylmethyl)-1H-benzotriazol-4-yl]oxy}phenyl)methanamine, Reverse Transcriptase
Authors:Yan, Y, Reid, J.
Deposit date:2011-07-21
Release date:2011-10-26
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Design and synthesis of conformationally constrained inhibitors of non-nucleoside reverse transcriptase.
J.Med.Chem., 54, 2011
4WT1
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BU of 4wt1 by Molmil
Complex of 70S ribosome with tRNA-Phe and mRNA with A-A mismatch in the second position in the A-site
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G.
Deposit date:2014-10-29
Release date:2015-06-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015
4WZO
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BU of 4wzo by Molmil
Complex of 70S ribosome with tRNA-fMet and mRNA
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G.
Deposit date:2014-11-20
Release date:2015-06-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015
8JAQ
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BU of 8jaq by Molmil
Structure of CRL2APPBP2 bound with RxxGP degron (tetramer)
Descriptor: Amyloid protein-binding protein 2, Cullin-2, E3 ubiquitin-protein ligase RBX1, ...
Authors:Zhao, S, Zhang, K, Xu, C.
Deposit date:2023-05-06
Release date:2023-10-18
Last modified:2023-10-25
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase.
Proc.Natl.Acad.Sci.USA, 120, 2023
8JAS
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BU of 8jas by Molmil
Structure of CRL2APPBP2 bound with RxxGPAA degron (tetramer)
Descriptor: Amyloid protein-binding protein 2, Cullin-2, E3 ubiquitin-protein ligase RBX1, ...
Authors:Zhao, S, Zhang, K, Xu, C.
Deposit date:2023-05-07
Release date:2023-10-18
Last modified:2023-10-25
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase.
Proc.Natl.Acad.Sci.USA, 120, 2023
8JAV
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BU of 8jav by Molmil
Structure of CRL2APPBP2 bound with the C-degron of MRPL28 (tetramer)
Descriptor: Amyloid protein-binding protein 2, Cullin-2, E3 ubiquitin-protein ligase RBX1, ...
Authors:Zhao, S, Zhang, K, Xu, C.
Deposit date:2023-05-07
Release date:2023-10-18
Last modified:2023-10-25
Method:ELECTRON MICROSCOPY (3.44 Å)
Cite:Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase.
Proc.Natl.Acad.Sci.USA, 120, 2023
5WII
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BU of 5wii by Molmil
TraE protein in complex with 2-Chloroisonicotinic Acid
Descriptor: 2-chloropyridine-4-carboxylic acid, Conjugal transfer protein
Authors:Casu, B, Arya, T, Bessette, B, Baron, C.
Deposit date:2017-07-19
Release date:2017-11-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Fragment-based screening identifies novel targets for inhibitors of conjugative transfer of antimicrobial resistance by plasmid pKM101.
Sci Rep, 7, 2017
5WIP
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BU of 5wip by Molmil
TraE protein in complex with 2-(2-furyl)isonicotinic acid
Descriptor: 2-(furan-2-yl)pyridine-4-carboxylic acid, Conjugal transfer protein
Authors:Casu, B, Arya, T, Bessette, B, Baron, C.
Deposit date:2017-07-19
Release date:2017-11-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Fragment-based screening identifies novel targets for inhibitors of conjugative transfer of antimicrobial resistance by plasmid pKM101.
Sci Rep, 7, 2017
3T19
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BU of 3t19 by Molmil
Crystal structure of HIV-1 reverse transcriptase (wild type) in complex with inhibitor M05
Descriptor: 1-(2,5-dichloro-3-{[5-chloro-1-(2H-pyrazolo[3,4-b]pyridin-3-ylmethyl)-1H-benzotriazol-4-yl]oxy}phenyl)methanamine, Reverse Transcriptase
Authors:Yan, Y, Reid, J.
Deposit date:2011-07-21
Release date:2011-10-26
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Design and synthesis of conformationally constrained inhibitors of non-nucleoside reverse transcriptase.
J.Med.Chem., 54, 2011
4V8G
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BU of 4v8g by Molmil
Crystal structure of RMF bound to the 70S ribosome.
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
Authors:Polikanov, Y.S, Blaha, G.M, Steitz, T.A.
Deposit date:2011-12-11
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:How hibernation factors RMF, HPF, and YfiA turn off protein synthesis.
Science, 336, 2012
4V9B
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BU of 4v9b by Molmil
Crystal Structure of the 70S ribosome with tigecycline.
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Jenner, L, Yusupov, M, Yusupova, G.
Deposit date:2012-07-18
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for potent inhibitory activity of the antibiotic tigecycline during protein synthesis.
Proc.Natl.Acad.Sci.USA, 110, 2013
4W2H
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BU of 4w2h by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with pactamycin (co-crystallized), mRNA and deacylated tRNA in the P site
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
Authors:Polikanov, Y.S, Osterman, I.A, Szal, T, Tashlitsky, V.N, Serebryakova, M.V, Kusochek, P, Bulkley, D, Malanicheva, I.A, Efimenko, T.A, Efremenkova, O.V, Konevega, A.L, Shaw, K.J, Bogdanov, A.A, Rodnina, M.V, Dontsova, O.A, Mankin, A.S, Steitz, T.A, Sergiev, P.V.
Deposit date:2014-09-12
Release date:2014-10-15
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome.
Mol.Cell, 56, 2014
4V5O
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BU of 4v5o by Molmil
CRYSTAL STRUCTURE OF THE EUKARYOTIC 40S RIBOSOMAL SUBUNIT IN COMPLEX WITH INITIATION FACTOR 1.
Descriptor: 18S RRNA, 40S RIBOSOMAL PROTEIN S12, 40S RIBOSOMAL PROTEIN S3A, ...
Authors:Rabl, J, Leibundgut, M, Ataide, S.F, Haag, A, Ban, N.
Deposit date:2010-11-26
Release date:2014-07-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.93 Å)
Cite:Crystal Structure of the Eukaryotic 40S Ribosomal Subunit in Complex with Initiation Factor 1.
Science, 331, 2011
4V63
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BU of 4v63 by Molmil
Structural basis for translation termination on the 70S ribosome.
Descriptor: 16S RRNA, 23S RRNA, 30S ribosomal protein S10, ...
Authors:Laurberg, M, Asahara, H, Korostelev, A, Zhu, J, Trakhanov, S, Noller, H.F.
Deposit date:2008-05-16
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.207 Å)
Cite:Structural basis for translation termination on the 70S ribosome
Nature, 454, 2008
4V7L
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BU of 4v7l by Molmil
The structures of viomycin bound to the 70S ribosome.
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Stanley, R.E, Blaha, G.
Deposit date:2009-11-12
Release date:2014-07-09
Last modified:2018-07-11
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome.
Nat.Struct.Mol.Biol., 17, 2010
4V87
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BU of 4v87 by Molmil
Crystal structure analysis of ribosomal decoding.
Descriptor: 16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
Authors:Demeshkina, N, Jenner, L, Yusupov, M, Yusupova, G.
Deposit date:2011-09-20
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A new understanding of the decoding principle on the ribosome.
Nature, 484, 2012
4V8P
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BU of 4v8p by Molmil
T.thermophila 60S ribosomal subunit in complex with initiation factor 6.
Descriptor: 26S RRNA, 5.8S RRNA, 5S RRNA, ...
Authors:Klinge, S, Voigts-Hoffmann, F, Leibundgut, M, Arpagaus, S, Ban, N.
Deposit date:2011-09-14
Release date:2014-07-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.52 Å)
Cite:Crystal Structure of the Eukaryotic 60S Ribosomal Subunit in Complex with Initiation Factor 6.
Science, 334, 2011
4V9R
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BU of 4v9r by Molmil
Crystal structure of antibiotic DITYROMYCIN bound to 70S ribosome
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
Authors:Bulkley, D.P, Brandi, L, Polikanov, Y.S, Fabbretti, A, O'Connor, M, Gualerzi, C.O, Steitz, T.A.
Deposit date:2013-12-05
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:The antibiotics dityromycin and GE82832 bind protein S12 and block EF-G-catalyzed translocation.
Cell Rep, 6, 2014
4V6G
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BU of 4v6g by Molmil
Initiation complex of 70S ribosome with two tRNAs and mRNA.
Descriptor: 16S RRNA (E.COLI NUMBERING), 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Jenner, L.B, Yusupova, G, Yusupov, M.
Deposit date:2009-07-10
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural aspects of messenger RNA reading frame maintenance by the ribosome.
Nat.Struct.Mol.Biol., 17, 2010
4V84
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BU of 4v84 by Molmil
Crystal structure of a complex containing domain 3 of CrPV IGR IRES RNA bound to the 70S ribosome.
Descriptor: 23S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Zhu, J, Korostelev, A, Costantino, D, Noller, H.F, Kieft, J.S.
Deposit date:2010-12-13
Release date:2014-07-09
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal structures of complexes containing domains from two viral internal ribosome entry site (IRES) RNAs bound to the 70S ribosome.
Proc.Natl.Acad.Sci.USA, 108, 2011

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数据于2024-10-09公开中

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