PDB: 59042 resultsInfo pagesStatus searchChemie searchBIRD

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8XLJ	Structure of the native glutamine synthetase in the adult cortex and hippocampus Descriptor: Glutamine synthetase Authors: Zhang, M, Feng, J, Li, Y, Zhu, S. Deposit date: 2023-12-26 Release date: 2025-02-05 Last modified: 2025-07-02 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Assembly and architecture of endogenous NMDA receptors in adult cerebral cortex and hippocampus. Cell, 188, 2025
6MTI	Synaptotagmin-1 C2A, C2B domains and SNARE-pin proteins (5CCI) individually docked into Cryo-EM map of C2AB-SNARE complexes helically organized on lipid nanotube surface in presence of Mg2+ Descriptor: MAGNESIUM ION, Synaptosomal-associated protein 25, Synaptotagmin-1, ... Authors: Grushin, K, Wang, J, Coleman, J, Rothman, J, Sindelar, C, Krishnakumar, S. Deposit date: 2018-10-19 Release date: 2019-04-24 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (10.4 Å) Cite: Structural basis for the clamping and Ca2+activation of SNARE-mediated fusion by synaptotagmin. Nat Commun, 10, 2019
6Y8C	Crystal structure of the cAMP-dependent protein kinase A cocrystallized with ATP and PKI (5-24) Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, DIMETHYL SULFOXIDE, ... Authors: Oebbeke, M, Heine, A, Klebe, G. Deposit date: 2020-03-04 Release date: 2020-09-30 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.76 Å) Cite: A crystallographic study of cAMP-dependent protein kinase A in complex with different Fasudil-derivatives To Be Published
3U60	Structure of T4 Bacteriophage Clamp Loader Bound To Open Clamp, DNA and ATP Analog Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA polymerase accessory protein 44, DNA polymerase accessory protein 62, ... Authors: Kelch, B.A, Makino, D.L, O'Donnell, M, Kuriyan, J. Deposit date: 2011-10-11 Release date: 2012-01-04 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (3.34 Å) Cite: How a DNA polymerase clamp loader opens a sliding clamp. Science, 334, 2011
7YQP	Xcc Nicotinamide Phosphoribosyltransferase Descriptor: Pre-B cell enhancing factor related protein Authors: Xu, G.L, Ming, Z.H. Deposit date: 2022-08-08 Release date: 2024-02-14 Last modified: 2024-09-04 Method: X-RAY DIFFRACTION (2.088 Å) Cite: Structural insights into Xanthomonas campestris pv. campestris NAD + biosynthesis via the NAM salvage pathway. Commun Biol, 7, 2024
7YQO	Xcc Nicotinamide Phosphoribosyltransferase Descriptor: GLYCEROL, Pre-B cell enhancing factor related protein Authors: Xu, G.L, Ming, Z.H. Deposit date: 2022-08-08 Release date: 2024-02-14 Last modified: 2024-09-04 Method: X-RAY DIFFRACTION (1.79 Å) Cite: Structural insights into Xanthomonas campestris pv. campestris NAD + biosynthesis via the NAM salvage pathway. Commun Biol, 7, 2024
5FRQ	Crystal Structure of Helicobacter pylori beta clamp bound to DNA ligase peptide Descriptor: DNA LIGASE, DNA POLYMERASE III SUBUNIT BETA Authors: Pandey, P, Gourinath, S. Deposit date: 2015-12-21 Release date: 2016-08-17 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structural Insight Into Beta-Clamp and its Interaction with DNA Ligase in Helicobacter Pylori Sci.Rep., 6, 2016
8FU6	GCGR-Gs complex in the presence of RAMP2 Descriptor: Glucagon derivative ZP3780, Glucagon receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... Authors: Krishna Kumar, K, O'Brien, E.S, Wang, H, Montabana, E, Kobilka, B.K. Deposit date: 2023-01-16 Release date: 2023-04-12 Last modified: 2024-11-06 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Negative allosteric modulation of the glucagon receptor by RAMP2. Cell, 186, 2023
4YS0	Conformational changes of the clamp of the protein translocation ATPase SecA from Thermotoga maritima Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Protein translocase subunit SecA Authors: Chen, Y, Rapoport, T.A. Deposit date: 2015-03-16 Release date: 2015-06-03 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.897 Å) Cite: Conformational Changes of the Clamp of the Protein Translocation ATPase SecA. J.Mol.Biol., 427, 2015
8Y57	Anti MDMA antibody 1bB11 complex Descriptor: (2S)-1-(1,3-benzodioxol-5-yl)-N-methylpropan-2-amine, Heavy chain of 1bB11, Light chain of 1bB11 Authors: Cheon, G, Lee, Y, Lee, S. Deposit date: 2024-01-31 Release date: 2024-12-11 Last modified: 2024-12-18 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Crystal structure of an antibody specifically recognizing 3,4-methyl enedioxy methamphetamine through the epoxide moiety. Biochem.Biophys.Res.Commun., 733, 2024
1UNN	Complex of beta-clamp processivity factor and little finger domain of PolIV Descriptor: DNA POLYMERASE III BETA SUBUNIT, DNA POLYMERASE IV, SULFATE ION Authors: Bunting, K.A, Roe, S.M, Pearl, L.H. Deposit date: 2003-09-11 Release date: 2003-11-06 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural Basis for Recruitment of Translesion DNA Polymerase Pol Iv/Dinb to the Beta-Clamp Embo J., 22, 2003
5G4Q	H.pylori Beta clamp in complex with 5-chloroisatin Descriptor: 5-chloro-1H-indole-2,3-dione, DNA POLYMERASE III SUBUNIT BETA Authors: Pandey, P, Gourinath, S. Deposit date: 2016-05-16 Release date: 2017-06-21 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Screening of E. coli beta-clamp Inhibitors Revealed that Few Inhibit Helicobacter pylori More Effectively: Structural and Functional Characterization. Antibiotics (Basel), 7, 2018
5G48	H.pylori Beta clamp in complex with Diflunisal Descriptor: 5-(2,4-DIFLUOROPHENYL)-2-HYDROXY-BENZOIC ACID, DNA POLYMERASE III SUBUNIT BETA Authors: Pandey, P, Gourinath, S. Deposit date: 2016-05-06 Release date: 2017-06-21 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.28 Å) Cite: Targeting the beta-clamp in Helicobacter pylori with FDA-approved drugs reveals micromolar inhibition by diflunisal. FEBS Lett., 591, 2017
3U5Z	Structure of T4 Bacteriophage clamp loader bound to the T4 clamp, primer-template DNA, and ATP analog Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA polymerase accessory protein 44, DNA polymerase accessory protein 62, ... Authors: Kelch, B.A, Makino, D.L, O'Donnell, M, Kuriyan, J. Deposit date: 2011-10-11 Release date: 2012-01-04 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (3.5 Å) Cite: How a DNA polymerase clamp loader opens a sliding clamp. Science, 334, 2011
3U61	Structure of T4 Bacteriophage Clamp Loader Bound To Closed Clamp, DNA and ATP Analog and ADP Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA polymerase accessory protein 44, DNA polymerase accessory protein 62, ... Authors: Kelch, B.A, Makino, D.L, O'Donnell, M, Kuriyan, J. Deposit date: 2011-10-11 Release date: 2012-01-04 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (3.2 Å) Cite: How a DNA polymerase clamp loader opens a sliding clamp. Science, 334, 2011
2KEC	Structure of SDF-1/CXCL12 Descriptor: Stromal cell-derived factor 1-alpha Authors: Volkman, B.F, Veldkamp, C.T, Peterson, F.C. Deposit date: 2009-01-28 Release date: 2009-09-29 Last modified: 2024-10-16 Method: SOLUTION NMR Cite: Monomeric structure of the cardioprotective chemokine SDF-1/CXCL12 Protein Sci., 18, 2009
2KED	Structure of SDF-1/CXCL12 Descriptor: Stromal cell-derived factor 1-alpha Authors: Volkman, B.F, Veldkamp, C.T, Peterson, F.C. Deposit date: 2009-01-28 Release date: 2009-09-29 Last modified: 2024-11-20 Method: SOLUTION NMR Cite: Monomeric structure of the cardioprotective chemokine SDF-1/CXCL12 Protein Sci., 18, 2009
8FQ1	GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 150mM CaCl2, 330uM CTZ, and 100mM L-glutamate (Open-Ca150) Descriptor: CALCIUM ION, Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit Authors: Nakagawa, T. Deposit date: 2023-01-05 Release date: 2024-02-28 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (5.59 Å) Cite: The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FQ5	GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 140mM NMDG, 330uM CTZ, and 100mM L-glutamate (Open-Na110) Descriptor: CHLORIDE ION, Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit Authors: Nakagawa, T. Deposit date: 2023-01-05 Release date: 2024-02-28 Last modified: 2024-10-09 Method: ELECTRON MICROSCOPY (2.34 Å) Cite: The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FP4	GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 500mM NaCl, 330uM CTZ, and 100mM glutamate (Open-Na610) Descriptor: CHLORIDE ION, Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit Authors: Nakagawa, T. Deposit date: 2023-01-04 Release date: 2024-02-28 Last modified: 2024-10-23 Method: ELECTRON MICROSCOPY (2.4 Å) Cite: The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FP9	GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100mM glutamate (Open-CaNaMg) Descriptor: CALCIUM ION, CHLORIDE ION, Glutamate receptor 2, ... Authors: Nakagawa, T. Deposit date: 2023-01-04 Release date: 2024-02-28 Last modified: 2024-11-13 Method: ELECTRON MICROSCOPY (2.44 Å) Cite: The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FQB	GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma2, with 10mM CaCl2, 140mM NMDG, 330uM CTZ, and 100mM L-glutamate (Open-Ca10) Descriptor: CALCIUM ION, CHLORIDE ION, Glutamate receptor 2, ... Authors: Nakagawa, T. Deposit date: 2023-01-05 Release date: 2024-02-28 Last modified: 2024-10-23 Method: ELECTRON MICROSCOPY (2.36 Å) Cite: The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FPG	GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100uM CNQX (Closed-CaNaMg) Descriptor: CHLORIDE ION, Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit Authors: Nakagawa, T. Deposit date: 2023-01-04 Release date: 2024-02-28 Last modified: 2024-10-30 Method: ELECTRON MICROSCOPY (2.32 Å) Cite: The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FPV	LBD conformation 1 (LBDconf1) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 500mM NaCl, 330uM CTZ, and 100mM glutamate (Open-Na610) Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2 Authors: Nakagawa, T. Deposit date: 2023-01-05 Release date: 2024-03-06 Last modified: 2024-11-06 Method: ELECTRON MICROSCOPY (3.08 Å) Cite: The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
8FPY	LBD conformation 2 (LBDconf2) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 500mM NaCl, 330uM CTZ, and 100mM glutamate (Open-Na610) Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2 Authors: Nakagawa, T. Deposit date: 2023-01-05 Release date: 2024-03-06 Last modified: 2024-11-13 Method: ELECTRON MICROSCOPY (2.98 Å) Cite: The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024

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