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1RWH
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BU of 1rwh by Molmil
Crystal structure of Arthrobacter aurescens chondroitin AC lyase in complex with chondroitin tetrasaccharide
Descriptor: 2,6-anhydro-3-deoxy-L-threo-hex-2-enonic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-2,6-anhydro-3-deoxy-L-xylo-hexonic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose, GLYCEROL, PHOSPHATE ION, ...
Authors:Lunin, V.V, Li, Y, Miyazono, H, Kyogashima, M, Bell, A.W, Cygler, M.
Deposit date:2003-12-16
Release date:2004-04-13
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:High-resolution crystal structure of Arthrobacter aurescens chondroitin AC lyase: an enzyme-substrate complex defines the catalytic mechanism
J.Mol.Biol., 337, 2004
4G35
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BU of 4g35 by Molmil
Mcl-1 in complex with a biphenyl cross-linked Noxa peptide.
Descriptor: 4,4'-bis(bromomethyl)biphenyl, Induced myeloid leukemia cell differentiation protein Mcl-1 homolog, Noxa BH3 peptide (cysteine-mediated cross-linked)
Authors:Drake, E, Edwardraja, S, Lin, Q, Gulick, A.M.
Deposit date:2012-07-13
Release date:2012-12-05
Last modified:2013-06-26
Method:X-RAY DIFFRACTION (2 Å)
Cite:Rational design of proteolytically stable, cell-permeable peptide-based selective Mcl-1 inhibitors.
J.Am.Chem.Soc., 134, 2012
4OGY
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BU of 4ogy by Molmil
Crystal structure of Fab DX-2930 in complex with human plasma kallikrein at 2.1 Angstrom resolution
Descriptor: 1,2-ETHANEDIOL, DX-2930 HEAVY CHAIN, DX-2930 LIGHT CHAIN, ...
Authors:Edwards, T.E, Clifton, M.C, Abendroth, J, Nixon, A, Ladner, R.
Deposit date:2014-01-16
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Inhibition of plasma kallikrein by a highly specific active site blocking antibody.
J.Biol.Chem., 289, 2014
2B3O
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BU of 2b3o by Molmil
Crystal structure of human tyrosine phosphatase SHP-1
Descriptor: Tyrosine-protein phosphatase, non-receptor type 6
Authors:Yang, J, Liu, L, He, D, Song, X, Liang, X, Zhao, Z.J, Zhou, G.W.
Deposit date:2005-09-20
Release date:2005-10-25
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of human protein-tyrosine phosphatase SHP-1.
J.Biol.Chem., 278, 2003
3HEK
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BU of 3hek by Molmil
HSP90 N-terminal domain in complex with 1-{4-[(2R)-1-(5-chloro-2,4-dihydroxybenzoyl)pyrrolidin-2-yl]benzyl}-3,3-difluoropyrrolidinium
Descriptor: Heat shock protein HSP 90-alpha, PHOSPHATE ION, [(2~{R})-2-[4-[[3,3-bis(fluoranyl)pyrrolidin-1-yl]methyl]phenyl]pyrrolidin-1-yl]-[5-chloranyl-2,4-bis(oxidanyl)phenyl]methanone
Authors:Gajiwala, K.S.
Deposit date:2009-05-08
Release date:2009-09-29
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Solution-phase parallel synthesis of Hsp90 inhibitors
J.Comb.Chem., 11
1JAE
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BU of 1jae by Molmil
STRUCTURE OF TENEBRIO MOLITOR LARVAL ALPHA-AMYLASE
Descriptor: ALPHA-AMYLASE, CALCIUM ION, CHLORIDE ION
Authors:Strobl, S, Maskos, K, Betz, M, Wiegand, G, Huber, R, Gomis-Rueth, F.X, Frank, G, Glockshuber, R.
Deposit date:1997-09-30
Release date:1998-11-04
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of yellow meal worm alpha-amylase at 1.64 A resolution.
J.Mol.Biol., 278, 1998
1WDN
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BU of 1wdn by Molmil
GLUTAMINE-BINDING PROTEIN
Descriptor: GLUTAMINE, GLUTAMINE BINDING PROTEIN
Authors:Sun, Y.-J, Rose, J, Wang, B.-C, Hsiao, C.-D.
Deposit date:1997-05-17
Release date:1998-05-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:The structure of glutamine-binding protein complexed with glutamine at 1.94 A resolution: comparisons with other amino acid binding proteins.
J.Mol.Biol., 278, 1998
4KYD
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BU of 4kyd by Molmil
Partial Structure of the C-terminal domain of the HPIV4B phosphoprotein, fused to MBP.
Descriptor: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, Maltose-binding periplasmic protein, Phosphoprotein, ...
Authors:Yegambaram, K, Bulloch, E.M.M, Kingston, R.L.
Deposit date:2013-05-28
Release date:2013-09-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Protein domain definition should allow for conditional disorder.
Protein Sci., 22, 2013
1RYI
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BU of 1ryi by Molmil
STRUCTURE OF GLYCINE OXIDASE WITH BOUND INHIBITOR GLYCOLATE
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLYCINE OXIDASE, GLYCOLIC ACID
Authors:Moertl, M, Diederichs, K, Welte, W, Pollegioni, L, Molla, G, Motteran, L, Andriolo, G, Pilone, M.S.
Deposit date:2003-12-22
Release date:2005-02-22
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure-function correlation in glycine oxidase from Bacillus subtilis
J.Biol.Chem., 279, 2004
2JU3
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BU of 2ju3 by Molmil
Solution-state NMR structures of apo-LFABP (Liver Fatty Acid-Binding Protein)
Descriptor: Fatty acid-binding protein, liver
Authors:He, Y, Yang, X, Wang, H, Estephan, R, Francis, F, Kodukula, S, Storch, J, Stark, R.E.
Deposit date:2007-08-14
Release date:2007-11-20
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution-State Molecular Structure of Apo and Oleate-Liganded Liver Fatty Acid-Binding Protein
Biochemistry, 46, 2007
1DSC
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BU of 1dsc by Molmil
NMR STUDY OF DNA (5'-D(*GP*AP*AP*GP*CP*TP*TP*C)-3') SELF-COMPLEMENTARY DUPLEX COMPLEXED WITH ACTINOMYCIN D, MINIMIZED AVERAGE STRUCTURE
Descriptor: ACTINOMYCIN D, DNA (5'-D(*GP*AP*AP*GP*CP*TP*TP*C)-3')
Authors:Lian, C, Robinson, H, Wang, A.H.-J.
Deposit date:1996-08-10
Release date:1996-12-07
Last modified:2024-07-10
Method:SOLUTION NMR
Cite:Structure of Actinomycin D Bound with (Gaagcttc)2 and (Gatgcttc)2 and its Binding to the (Cag)N:(Ctg)N Triplet Sequence by NMR Analysis
J.Am.Chem.Soc., 118, 1996
2ATC
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BU of 2atc by Molmil
CRYSTAL AND MOLECULAR STRUCTURES OF NATIVE AND CTP-LIGANDED ASPARTATE CARBAMOYLTRANSFERASE FROM ESCHERICHIA COLI
Descriptor: ASPARTATE CARBAMOYLTRANSFERASE, CATALYTIC CHAIN, REGULATORY CHAIN, ...
Authors:Honzatko, R.B, Crawford, J.L, Monaco, H.L, Ladner, J.E, Edwards, B.F.P, Evans, D.R, Warren, S.G, Wiley, D.C, Ladner, R.C, Lipscomb, W.N.
Deposit date:1982-03-24
Release date:1982-12-07
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal and molecular structures of native and CTP-liganded aspartate carbamoyltransferase from Escherichia coli.
J.Mol.Biol., 160, 1982
8ACN
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BU of 8acn by Molmil
CRYSTAL STRUCTURES OF ACONITASE WITH ISOCITRATE AND NITROISOCITRATE BOUND
Descriptor: ACONITASE, IRON/SULFUR CLUSTER, NITROISOCITRIC ACID
Authors:Lauble, H, Kennedy, M.C, Beinert, H, Stout, C.D.
Deposit date:1991-05-15
Release date:1993-10-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of aconitase with isocitrate and nitroisocitrate bound.
Biochemistry, 31, 1992
8ABP
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BU of 8abp by Molmil
SUGAR-BINDING AND CRYSTALLOGRAPHIC STUDIES OF AN ARABINOSE-BINDING PROTEIN MUTANT (MET108LEU) WHICH EXHIBITS ENHANCED AFFINITY AND ALTERED SPECIFICITY
Descriptor: L-ARABINOSE-BINDING PROTEIN, alpha-D-galactopyranose, beta-D-galactopyranose
Authors:Vermersch, P.S, Tesmer, J.J.G, Quiocho, F.A.
Deposit date:1991-04-25
Release date:1991-10-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Sugar-binding and crystallographic studies of an arabinose-binding protein mutant (Met108Leu) that exhibits enhanced affinity and altered specificity.
Biochemistry, 30, 1991
8AME
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BU of 8ame by Molmil
TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 N14SA16H
Descriptor: PROTEIN (ANTIFREEZE PROTEIN TYPE III)
Authors:Graether, S.P, Deluca, C.I, Baardsnes, J, Hill, G.A, Davies, P.L, Jia, Z.
Deposit date:1999-01-24
Release date:1999-04-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Quantitative and qualitative analysis of type III antifreeze protein structure and function.
J.Biol.Chem., 274, 1999
6YDG
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BU of 6ydg by Molmil
X-ray structure of LPMO
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Auxiliary activity 9, CHLORIDE ION, ...
Authors:Tandrup, T, Tryfona, T, Frandsen, K.E.H, Johansen, K.S, Dupree, P, Lo Leggio, L.
Deposit date:2020-03-20
Release date:2020-09-16
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Oligosaccharide Binding and Thermostability of Two Related AA9 Lytic Polysaccharide Monooxygenases.
Biochemistry, 59, 2020
6YJS
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BU of 6yjs by Molmil
Crystal structure of MGAT5 (alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase V) luminal domain with a Lys329-Ile345 loop truncation, in complex with biantennary pentasaccharide M592
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose, ...
Authors:Wu, L, Darby, J.F, Gilio, A.K, Davies, G.J.
Deposit date:2020-04-04
Release date:2020-08-05
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Substrate Engagement and Catalytic Mechanisms of N-Acetylglucosaminyltransferase V
Acs Catalysis, 2020
8J83
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BU of 8j83 by Molmil
Crystal structure of formate dehydrogenase from Methylorubrum extorquens AM1
Descriptor: 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, DI(HYDROXYETHYL)ETHER, FE2/S2 (INORGANIC) CLUSTER, ...
Authors:Kobayashi, A, Taketa, M, Sowa, K, Kano, K, Higuchi, Y, Ogata, H.
Deposit date:2023-04-29
Release date:2023-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure and function relationship of formate dehydrogenases: an overview of recent progress.
Iucrj, 10, 2023
3VWI
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BU of 3vwi by Molmil
High resolution crystal structure of FraC in the monomeric form
Descriptor: AMMONIUM ION, CHLORIDE ION, Fragaceatoxin C, ...
Authors:Tanaka, K, Morante, K, Caaveiro, J.M.M, Gonzalez-Manas, J.M, Tsumoto, K.
Deposit date:2012-08-23
Release date:2013-08-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for self-assembly of a cytolytic pore lined by protein and lipid
Nat Commun, 6, 2015
6Y5D
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BU of 6y5d by Molmil
Structure of human cGAS (K394E) bound to the nucleosome
Descriptor: Cyclic GMP-AMP synthase, DNA (153-MER), Histone H2A type 2-A, ...
Authors:Pathare, G.R, Cavadini, S, Kempf, G, Thoma, N.H.
Deposit date:2020-02-25
Release date:2020-09-23
Last modified:2020-12-09
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural mechanism of cGAS inhibition by the nucleosome.
Nature, 587, 2020
2IX8
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BU of 2ix8 by Molmil
MODEL FOR EEF3 BOUND TO AN 80S RIBOSOME
Descriptor: ELONGATION FACTOR 3A
Authors:Andersen, C.B.F, Becker, T, Blau, M, Anand, M, Halic, M, Balar, B, Mielke, T, Boesen, T, Pedersen, J.S, Spahn, C.M.T, Kinzy, T.G, Andersen, G.R, Beckmann, R.
Deposit date:2006-07-07
Release date:2007-07-10
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Structure of Eef3 and the Mechanism of Transfer RNA Release from the E-Site.
Nature, 443, 2006
8ASD
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BU of 8asd by Molmil
Structure of the SFTSV L protein stalled at late elongation [LATE-ELONGATION]
Descriptor: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, MAGNESIUM ION, RNA (5'-R(P*AP*AP*AP*AP*AP*AP*GP*AP*UP*CP*UP*GP*GP*GP*CP*GP*GP*UP*CP*UP*UP*UP*GP*UP*GP*U)-3'), ...
Authors:Williams, H.M, Thorkelsson, S.R, Vogel, D, Milewski, M, Busch, C, Cusack, S, Grunewald, K, Quemin, E.R.J, Rosenthal, M.
Deposit date:2022-08-19
Release date:2023-01-18
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural insights into viral genome replication by the severe fever with thrombocytopenia syndrome virus L protein.
Nucleic Acids Res., 51, 2023
6YJV
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BU of 6yjv by Molmil
Crystal structure of unliganded MGAT5 (alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase V) luminal domain with a Lys329-Ile345 loop truncation, in complex with UDP-2-deoxy-2-fluoroglucose and biantennary pentasaccharide M592
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose, ...
Authors:Wu, L, Darby, J.F, Gilio, A.K, Davies, G.J.
Deposit date:2020-04-04
Release date:2020-08-05
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Substrate Engagement and Catalytic Mechanisms of N-Acetylglucosaminyltransferase V
Acs Catalysis, 2020
1TPZ
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BU of 1tpz by Molmil
Crystal Structure of IIGP1: a paradigm for interferon inducible p47 resistance GTPases
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Ghosh, A, Uthaiah, R, Howard, J, Herrmann, C, Wolf, E.
Deposit date:2004-06-16
Release date:2004-09-21
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of IIGP1; A Paradigm for Interferon-Inducible p47 Resistance GTPases
Mol.Cell, 15, 2004
1U1P
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BU of 1u1p by Molmil
Crystal Structure of UP1 Complexed With d(TTAGGGTTA 2PR GG); A Human Telomeric Repeat Containing 2-aminopurine
Descriptor: 5'-D(*T*TP*AP*GP*GP*GP*TP*TP*AP*(2PR)P*GP*G)-3', Heterogeneous nuclear ribonucleoprotein A1
Authors:Myers, J.C, Shamoo, Y.
Deposit date:2004-07-15
Release date:2004-09-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Human UP1 as a Model for Understanding Purine Recognition in the Family of Proteins Containing the RNA Recognition Motif (RRM).
J.Mol.Biol., 342, 2004

225399

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