5YNM
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![BU of 5ynm by Molmil](/molmil-images/mine/5ynm) | Crystal structure of MERS-CoV nsp16/nsp10 complex bound to SAM and m7GpppA | Descriptor: | P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, S-ADENOSYLMETHIONINE, ZINC ION, ... | Authors: | Wei, S.M, Yang, L, Ke, Z.H, Guo, D.Y, Fan, C.P. | Deposit date: | 2017-10-24 | Release date: | 2018-12-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Structural insights into the molecular mechanism of MERS Coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex To Be Published
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5JHW
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4N7O
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![BU of 4n7o by Molmil](/molmil-images/mine/4n7o) | Capturing the haemoglobin allosteric transition in a single crystal form; Crystal structure of half-liganded human haemoglobin with phosphate at 2.5 A resolution. | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Sugiyama, K, Shibayama, N, Park, S.Y. | Deposit date: | 2013-10-16 | Release date: | 2014-04-02 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.502 Å) | Cite: | Capturing the hemoglobin allosteric transition in a single crystal form J.Am.Chem.Soc., 136, 2014
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2X2D
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![BU of 2x2d by Molmil](/molmil-images/mine/2x2d) | acetyl-CypA:HIV-1 N-term capsid domain complex | Descriptor: | CAPSID PROTEIN P24, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A | Authors: | Lammers, M, Neumann, H, Chin, J.W, James, L.C. | Deposit date: | 2010-01-12 | Release date: | 2010-03-23 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Acetylation Regulates Cyclophilin a Catalysis, Immunosuppression and HIV Isomerisation Nat.Chem.Biol., 6, 2010
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1ZMO
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![BU of 1zmo by Molmil](/molmil-images/mine/1zmo) | Apo structure of haloalcohol dehalogenase HheA of Arthrobacter sp. AD2 | Descriptor: | halohydrin dehalogenase | Authors: | de Jong, R.M, Kalk, K.H, Tang, L, Janssen, D.B, Dijkstra, B.W. | Deposit date: | 2005-05-10 | Release date: | 2006-04-25 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The X-ray structure of the haloalcohol dehalogenase HheA from Arthrobacter sp. strain AD2: insight into enantioselectivity and halide binding in the haloalcohol dehalogenase family. J.Bacteriol., 188, 2006
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4DAI
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![BU of 4dai by Molmil](/molmil-images/mine/4dai) | Crystal structure of B. anthracis DHPS with compound 23 | Descriptor: | (7-amino-4,5-dioxo-1,4,5,6-tetrahydropyrimido[4,5-c]pyridazin-3-yl)acetic acid, Dihydropteroate Synthase, SULFATE ION | Authors: | Hammoudeh, D, Lee, R.E, White, S.W. | Deposit date: | 2012-01-12 | Release date: | 2012-03-28 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure-Based Design of Novel Pyrimido[4,5-c]pyridazine Derivatives as Dihydropteroate Synthase Inhibitors with Increased Affinity. Chemmedchem, 7, 2012
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4N7N
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2OJ3
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![BU of 2oj3 by Molmil](/molmil-images/mine/2oj3) | Hepatitis Delta Virus ribozyme precursor structure, with C75U mutation, bound to Tl+ and cobalt hexammine (Co(NH3)63+) | Descriptor: | COBALT HEXAMMINE(III), HDV RIBOZYME, THALLIUM (I) ION, ... | Authors: | Ke, A, Ding, F, Batchelor, J.D, Doudna, J.A. | Deposit date: | 2007-01-12 | Release date: | 2007-03-27 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural roles of monovalent cations in the HDV ribozyme. Structure, 15, 2007
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3FWO
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![BU of 3fwo by Molmil](/molmil-images/mine/3fwo) | The large ribosomal subunit from Deinococcus radiodurans complexed with Methymycin | Descriptor: | (3R,4S,5S,7R,9E,11S,12R)-12-ethyl-11-hydroxy-3,5,7,11-tetramethyl-2,8-dioxooxacyclododec-9-en-4-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside, 23S RIBOSOMAL RNA, 5S RIBOSOMAL RNA | Authors: | Auerbach, T, Mermershtain, I, Bashan, A, Davidovich, C, Rozenberg, H, Sherman, D.H, Yonath, A. | Deposit date: | 2009-01-19 | Release date: | 2010-01-19 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.71 Å) | Cite: | Structural basis for the antibacterial activity of the 12-membered-ring mono-sugar macrolide methymycin Biotechnologia, 1, 2009
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2H6M
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![BU of 2h6m by Molmil](/molmil-images/mine/2h6m) | An episulfide cation (thiiranium ring) trapped in the active site of HAV 3C proteinase inactivated by peptide-based ketone inhibitors | Descriptor: | N-ACETYL-LEUCYL-ALANYL-ALANYL-(N,N-DIMETHYL)-GLUTAMINE-(1,4-DIOXO-3,4-DIHYDRO-1H-PHTHALAZIN-2-YL)METHYLKETONE INHIBITOR, N-[(BENZYLOXY)CARBONYL]-L-ALANINE, Picornain 3C | Authors: | Yin, J, Cherney, M.M, Bergmann, E.M, James, M.N. | Deposit date: | 2006-05-31 | Release date: | 2006-08-08 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | An episulfide cation (thiiranium ring) trapped in the active site of HAV 3C proteinase inactivated by peptide-based ketone inhibitors. J.Mol.Biol., 361, 2006
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7M50
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4NQW
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![BU of 4nqw by Molmil](/molmil-images/mine/4nqw) | |
3AHW
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1ZJM
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![BU of 1zjm by Molmil](/molmil-images/mine/1zjm) | Human DNA Polymerase beta complexed with DNA containing an A-A mismatched primer terminus | Descriptor: | 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3', 5'-D(P*GP*TP*CP*GP*G)-3', DNA polymerase beta, ... | Authors: | Batra, V.K, Beard, W.A, Shock, D.D, Pedersen, L.C, Wilson, S.H. | Deposit date: | 2005-04-29 | Release date: | 2005-08-16 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Nucleotide-induced DNA polymerase active site motions accommodating a mutagenic DNA intermediate. STRUCTURE, 13, 2005
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2QNC
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![BU of 2qnc by Molmil](/molmil-images/mine/2qnc) | Crystal structure of T4 Endonuclease VII N62D mutant in complex with a DNA Holliday junction | Descriptor: | 1,2-ETHANEDIOL, DNA (5'-D(*DAP*DGP*DGP*DCP*DCP*DTP*DAP*DGP*DCP*DGP*DTP*DCP*DCP*DGP*DGP*DAP*DAP*DTP*DTP*DCP*DTP*DTP*DCP*DG)-3'), DNA (5'-D(*DCP*DAP*DCP*DAP*DTP*DCP*DGP*DAP*DTP*DGP*DGP*DAP*DGP*DCP*DCP*DGP*DCP*DTP*DAP*DGP*DGP*DCP*DCP*DT)-3'), ... | Authors: | Biertumpfel, C, Yang, W, Suck, D. | Deposit date: | 2007-07-18 | Release date: | 2008-01-29 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Crystal structure of T4 endonuclease VII resolving a Holliday junction. Nature, 449, 2007
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4V3R
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![BU of 4v3r by Molmil](/molmil-images/mine/4v3r) | Designed armadillo repeat protein with 5 internal repeats, 2nd generation C-cap and 3rd generation N-cap. | Descriptor: | MAGNESIUM ION, YIII_M5_AII | Authors: | Reichen, C, Madhurantakam, C, Pluckthun, A, Mittl, P. | Deposit date: | 2014-10-20 | Release date: | 2016-01-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structures of Designed Armadillo-Repeat Proteins Show Propagation of Inter-Repeat Interface Effects Acta Crystallogr.,Sect.D, 72, 2016
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3DC4
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![BU of 3dc4 by Molmil](/molmil-images/mine/3dc4) | Crystal structure of the Drosophila kinesin family member NOD in complex with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein Nod, MAGNESIUM ION | Authors: | Cochran, J.C, Mulko, N.K, Kull, F.J. | Deposit date: | 2008-06-03 | Release date: | 2009-02-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | ATPase cycle of the nonmotile kinesin NOD allows microtubule end tracking and drives chromosome movement. Cell(Cambridge,Mass.), 136, 2009
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3DCB
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![BU of 3dcb by Molmil](/molmil-images/mine/3dcb) | Crystal structure of the Drosophila kinesin family member NOD in complex with AMPPNP | Descriptor: | Kinesin-like protein Nod, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Cochran, J.C, Mulko, N.K, Kull, F.J. | Deposit date: | 2008-06-03 | Release date: | 2009-02-10 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | ATPase cycle of the nonmotile kinesin NOD allows microtubule end tracking and drives chromosome movement. Cell(Cambridge,Mass.), 136, 2009
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1SJF
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![BU of 1sjf by Molmil](/molmil-images/mine/1sjf) | Crystal Structure of the Hepatitis Delta Virus Gemonic Ribozyme Precursor, with C75U mutaion, in Cobalt Hexammine solution | Descriptor: | COBALT HEXAMMINE(III), Hepatitis Delta virus ribozyme, U1 small nuclear ribonucleoprotein A | Authors: | Ke, A, Zhou, K, Ding, F, Cate, J.H.D, Doudna, J.A. | Deposit date: | 2004-03-03 | Release date: | 2004-05-18 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | A conformational switch controls hepatitis delta virus ribozyme catalysis. Nature, 429, 2004
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3VD0
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![BU of 3vd0 by Molmil](/molmil-images/mine/3vd0) | structure of p73 DNA binding domain tetramer modulates p73 transactivation | Descriptor: | DNA (5'-D(*CP*AP*GP*GP*CP*AP*TP*GP*CP*CP*TP*G)-3'), Tumor protein p73, ZINC ION | Authors: | Ethayathulla, A.S, Tse, P.W, Nguyen, S, Viadiu, H. | Deposit date: | 2012-01-04 | Release date: | 2012-04-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structure of p73 DNA-binding domain tetramer modulates p73 transactivation. Proc.Natl.Acad.Sci.USA, 109, 2012
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5K8H
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3VD1
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![BU of 3vd1 by Molmil](/molmil-images/mine/3vd1) | structure of p73 DNA binding domain tetramer modulates p73 transactivation | Descriptor: | DNA (5'-D(*CP*GP*GP*GP*CP*AP*TP*GP*CP*CP*CP*G)-3'), Tumor protein p73, ZINC ION | Authors: | Ethayathulla, A.S, Tse, P.W, Nguyen, S, Viadiu, H. | Deposit date: | 2012-01-04 | Release date: | 2012-04-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structure of p73 DNA-binding domain tetramer modulates p73 transactivation. Proc.Natl.Acad.Sci.USA, 109, 2012
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3VD2
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![BU of 3vd2 by Molmil](/molmil-images/mine/3vd2) | structure of p73 DNA binding domain tetramer modulates p73 transactivation | Descriptor: | DNA (5'-D(*AP*TP*GP*GP*AP*CP*AP*TP*GP*TP*CP*CP*AP*T)-3'), Tumor protein p73, ZINC ION | Authors: | Ethayathulla, A.S, Tse, P.W, Nguyen, S, Viadiu, H. | Deposit date: | 2012-01-04 | Release date: | 2012-04-18 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Structure of p73 DNA-binding domain tetramer modulates p73 transactivation. Proc.Natl.Acad.Sci.USA, 109, 2012
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6AF0
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![BU of 6af0 by Molmil](/molmil-images/mine/6af0) | Structure of Ctr9, Paf1 and Cdc73 ternary complex from Myceliophthora thermophila | Descriptor: | Cdc73 protein, Ctr9 protein, Paf1 protein | Authors: | Wang, Z, Deng, P, Zhou, Y. | Deposit date: | 2018-08-07 | Release date: | 2018-09-19 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.88 Å) | Cite: | Transcriptional elongation factor Paf1 core complex adopts a spirally wrapped solenoidal topology. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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7EGT
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![BU of 7egt by Molmil](/molmil-images/mine/7egt) | The crystal structure of the C-terminal domain of T. thermophilus UvrD complexed with the N-terminal domain of UvrB | Descriptor: | DNA helicase UvrD, UvrABC system protein B | Authors: | Zheng, F, Shen, L, Li, L, Zhang, Y. | Deposit date: | 2021-03-26 | Release date: | 2022-04-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.581 Å) | Cite: | Crucial role and mechanism of transcription-coupled DNA repair in bacteria. Nature, 604, 2022
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