Human DNA Polymerase beta complexed with DNA containing an A-A mismatched primer terminus

Summary for 1ZJM

Descriptord(*CP*CP*GP*AP*CP*CP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... (6 entities in total)
Functional Keywordsnucleotidyltransferase, dna repair, dna mismatch, base excision repair, dna-lyase-transferase complex, dna/lyase/transferase
Biological sourceHomo sapiens (human)
Cellular locationNucleus P06746
Total number of polymer chains4
Total molecular weight47744.84
Batra, V.K.,Beard, W.A.,Shock, D.D.,Pedersen, L.C.,Wilson, S.H. (deposition date: 2005-04-29, release date: 2005-08-16, Last modification date: 2011-07-13)
Primary citation
Batra, V.K.,Beard, W.A.,Shock, D.D.,Pedersen, L.C.,Wilson, S.H.
Nucleotide-induced DNA polymerase active site motions accommodating a mutagenic DNA intermediate.
STRUCTURE, 13:1225-1233, 2005
PubMed: 16084394 (PDB entries with the same primary citation)
DOI: 10.1016/j.str.2005.05.010
MImport into Mendeley
Experimental method
NMR Information

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.24170.3%0.4%1.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution