PDB: 2832 resultsInfo pagesStatus searchChemie searchBIRD

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6FTG	Subtomogram average of OST-containing ribosome-translocon complexes from canine rough microsomal membranes Descriptor: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... Authors: Pfeffer, S, Foerster, F. Deposit date: 2018-02-22 Release date: 2018-03-21 Last modified: 2020-07-29 Method: ELECTRON MICROSCOPY (9.1 Å) Cite: Structural basis for coupling protein transport and N-glycosylation at the mammalian endoplasmic reticulum. Science, 360, 2018
7NWH	Mammalian pre-termination 80S ribosome with eRF1 and eRF3 bound by Blasticidin S. Descriptor: 18S Ribosomal RNA, 28S Ribosomal RNA, 40S ribosomal protein S10, ... Authors: Powers, K.T, Yadav, S.K.N, Bufton, J.C, Schaffitzel, C. Deposit date: 2021-03-16 Release date: 2021-07-07 Last modified: 2023-01-11 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA. Nucleic Acids Res., 49, 2021
8FCN	Cryo-EM structure of p97:UBXD1 VIM-only state Descriptor: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase, UBX domain-containing protein 6 Authors: Braxton, J.R, Tucker, M.R, Tse, E, Southworth, D.R. Deposit date: 2022-12-01 Release date: 2023-06-21 Last modified: 2023-12-20 Method: ELECTRON MICROSCOPY (2.95 Å) Cite: The p97/VCP adaptor UBXD1 drives AAA+ remodeling and ring opening through multi-domain tethered interactions. Nat.Struct.Mol.Biol., 30, 2023
4DDH	Pantothenate synthetase in complex with 6-methoxy-1-benzofuran-3-yl acetic acid Descriptor: (6-methoxy-1-benzofuran-3-yl)acetic acid, 1,2-ETHANEDIOL, ETHANOL, ... Authors: Silvestre, H.L. Deposit date: 2012-01-18 Release date: 2013-02-13 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.07 Å) Cite: Integrated biophysical approach to fragment screening and validation for fragment-based lead discovery. Proc.Natl.Acad.Sci.USA, 110, 2013
8OOI	Full composite cryo-EM map of p97/VCP in ADP.Pi state Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Cheng, T.C, Sakata, E, Schuetz, A.K. Deposit date: 2023-04-05 Release date: 2024-01-31 Last modified: 2024-03-13 Method: ELECTRON MICROSCOPY (2.61 Å) Cite: Characterizing ATP processing by the AAA+ protein p97 at the atomic level. Nat.Chem., 16, 2024
8FCT	Cryo-EM structure of p97:UBXD1 lariat mutant Descriptor: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase, UBX domain-containing protein 6 Authors: Braxton, J.R, Tucker, M.R, Tse, E, Southworth, D.R. Deposit date: 2022-12-01 Release date: 2023-06-21 Last modified: 2023-12-20 Method: ELECTRON MICROSCOPY (3.42 Å) Cite: The p97/VCP adaptor UBXD1 drives AAA+ remodeling and ring opening through multi-domain tethered interactions. Nat.Struct.Mol.Biol., 30, 2023
2IY5	PHENYLALANYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS complexed with tRNA and a phenylalanyl-adenylate analog Descriptor: ADENOSINE-5'-[PHENYLALANINOL-PHOSPHATE], MAGNESIUM ION, PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN, ... Authors: Moor, N, Kotik-Kogan, O, Tworowski, D, Sukhanova, M, Safro, M. Deposit date: 2006-07-12 Release date: 2006-09-06 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (3.1 Å) Cite: The crystal structure of the ternary complex of phenylalanyl-tRNA synthetase with tRNAPhe and a phenylalanyl-adenylate analogue reveals a conformational switch of the CCA end. Biochemistry, 45, 2006
8FCP	Cryo-EM structure of p97:UBXD1 para state Descriptor: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase, UBX domain-containing protein 6 Authors: Braxton, J.R, Tucker, M.R, Tse, E, Southworth, D.R. Deposit date: 2022-12-01 Release date: 2023-06-21 Last modified: 2023-12-20 Method: ELECTRON MICROSCOPY (3.52 Å) Cite: The p97/VCP adaptor UBXD1 drives AAA+ remodeling and ring opening through multi-domain tethered interactions. Nat.Struct.Mol.Biol., 30, 2023
8FCR	Cryo-EM structure of p97:UBXD1 H4-bound state Descriptor: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase, UBX domain-containing protein 6 Authors: Braxton, J.R, Tucker, M.R, Tse, E, Southworth, D.R. Deposit date: 2022-12-01 Release date: 2023-06-21 Last modified: 2023-12-20 Method: ELECTRON MICROSCOPY (4.12 Å) Cite: The p97/VCP adaptor UBXD1 drives AAA+ remodeling and ring opening through multi-domain tethered interactions. Nat.Struct.Mol.Biol., 30, 2023
8FCL	Cryo-EM structure of p97:UBXD1 closed state Descriptor: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase, UBX domain-containing protein 6 Authors: Braxton, J.R, Tucker, M.R, Tse, E, Southworth, D.R. Deposit date: 2022-12-01 Release date: 2023-06-21 Last modified: 2023-12-20 Method: ELECTRON MICROSCOPY (3.51 Å) Cite: The p97/VCP adaptor UBXD1 drives AAA+ remodeling and ring opening through multi-domain tethered interactions. Nat.Struct.Mol.Biol., 30, 2023
8FCQ	Cryo-EM structure of p97:UBXD1 PUB-in state Descriptor: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase, UBX domain-containing protein 6 Authors: Braxton, J.R, Tucker, M.R, Tse, E, Southworth, D.R. Deposit date: 2022-12-01 Release date: 2023-06-21 Last modified: 2023-12-20 Method: ELECTRON MICROSCOPY (3.93 Å) Cite: The p97/VCP adaptor UBXD1 drives AAA+ remodeling and ring opening through multi-domain tethered interactions. Nat.Struct.Mol.Biol., 30, 2023
8FCO	Cryo-EM structure of p97:UBXD1 meta state Descriptor: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase, UBX domain-containing protein 6 Authors: Braxton, J.R, Tucker, M.R, Tse, E, Southworth, D.R. Deposit date: 2022-12-01 Release date: 2023-06-21 Last modified: 2023-12-20 Method: ELECTRON MICROSCOPY (3.31 Å) Cite: The p97/VCP adaptor UBXD1 drives AAA+ remodeling and ring opening through multi-domain tethered interactions. Nat.Struct.Mol.Biol., 30, 2023
8FCM	Cryo-EM structure of p97:UBXD1 open state Descriptor: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase, UBX domain-containing protein 6 Authors: Braxton, J.R, Tucker, M.R, Tse, E, Southworth, D.R. Deposit date: 2022-12-01 Release date: 2023-06-21 Last modified: 2023-12-20 Method: ELECTRON MICROSCOPY (3.27 Å) Cite: The p97/VCP adaptor UBXD1 drives AAA+ remodeling and ring opening through multi-domain tethered interactions. Nat.Struct.Mol.Biol., 30, 2023
1RIQ	The crystal structure of the catalytic fragment of the alanyl-tRNA synthetase Descriptor: Alanyl-tRNA synthetase Authors: Swairjo, M.A, Otero, F.J, Yang, X.-L, Lovato, M.A, Skene, R.J, McRee, D.E, Ribas de Pouplana, L, Schimmel, P. Deposit date: 2003-11-17 Release date: 2004-04-06 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.14 Å) Cite: Alanyl-tRNA Synthetase Crystal Structure and Design for Acceptor-Stem Recognition Mol.Cell, 13, 2004
6SYF	Human Ubc9 with covalent isopeptide ligand Descriptor: ACE-ILE-LYS-GLN-GLU, ACE-LEU-ARG-LEU-ARG-GLY-CYS, SUMO-conjugating enzyme UBC9 Authors: Hofmann, R, Akimoto, G, Wucherpfennig, T.G, Zeymer, C, Bode, J.W. Deposit date: 2019-09-27 Release date: 2020-08-12 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Lysine acylation using conjugating enzymes for site-specific modification and ubiquitination of recombinant proteins. Nat.Chem., 12, 2020
3AMT	Crystal structure of the TiaS-tRNA(Ile2)-ATP complex Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Putative uncharacterized protein, RNA (78-MER) Authors: Numata, T, Osawa, T. Deposit date: 2010-08-23 Release date: 2011-10-12 Last modified: 2013-06-19 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structural basis of tRNA agmatinylation essential for AUA codon decoding Nat.Struct.Mol.Biol., 18, 2011
5KNL	Crystal structure of S. pombe ubiquitin E1 (Uba1) in complex with Ubc15 and ubiquitin Descriptor: SULFATE ION, Ubiquitin, Ubiquitin-activating enzyme E1 1, ... Authors: Olsen, S.K, Lv, Z, Yuan, L, Williams, K. Deposit date: 2016-06-28 Release date: 2017-02-15 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.5 Å) Cite: S. pombe Uba1-Ubc15 Structure Reveals a Novel Regulatory Mechanism of Ubiquitin E2 Activity. Mol. Cell, 65, 2017
7LN0	Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and Ub6 (Class 2) Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Hexa-ubiquitin, ... Authors: Pan, M, Yu, Y, Liu, L, Zhao, M. Deposit date: 2021-02-06 Release date: 2021-09-15 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (2.98 Å) Cite: Mechanistic insight into substrate processing and allosteric inhibition of human p97. Nat.Struct.Mol.Biol., 28, 2021
7LN6	Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and polyubiquitinated Ub-Eos (CHAPSO, Class 2, Open State) Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Pan, M, Yu, Y, Liu, L, Zhao, M. Deposit date: 2021-02-06 Release date: 2021-09-15 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (3.58 Å) Cite: Mechanistic insight into substrate processing and allosteric inhibition of human p97. Nat.Struct.Mol.Biol., 28, 2021
7LN5	Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and polyubiquitinated Ub-Eos (CHAPSO, Class 1, Close State) Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Pan, M, Yu, Y, Liu, L, Zhao, M. Deposit date: 2021-02-06 Release date: 2021-09-15 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (3.09 Å) Cite: Mechanistic insight into substrate processing and allosteric inhibition of human p97. Nat.Struct.Mol.Biol., 28, 2021
7LN1	Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and Ub6 (Class 3) Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Hexa-ubiquitin, ... Authors: Pan, M, Yu, Y, Liu, L, Zhao, M. Deposit date: 2021-02-06 Release date: 2021-09-15 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Mechanistic insight into substrate processing and allosteric inhibition of human p97. Nat.Struct.Mol.Biol., 28, 2021
7LN3	Cryo-EM structure of human p97 in complex with Npl4/Ufd1 and polyubiquitinated Ub-Eos (FOM, Class 2) Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Pan, M, Yu, Y, Liu, L, Zhao, M. Deposit date: 2021-02-06 Release date: 2021-09-15 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (3.45 Å) Cite: Mechanistic insight into substrate processing and allosteric inhibition of human p97. Nat.Struct.Mol.Biol., 28, 2021
7MDM	Structure of human p97 ATPase L464P mutant Descriptor: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase Authors: Zhang, X, Gui, L, Li, S, Nandi, P, Columbres, R.C, Wong, D.E, Moen, D.R, Lin, H.J, Chiu, P.-L, Chou, T.-F. Deposit date: 2021-04-05 Release date: 2021-08-25 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (4.86 Å) Cite: Conserved L464 in p97 D1-D2 linker is critical for p97 cofactor regulated ATPase activity. Biochem.J., 478, 2021
1NI5	Structure of the MesJ PP-ATPase from Escherichia Coli Descriptor: Putative cell cycle protein mesJ Authors: Gu, M, Burling, T, Lima, C.D, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) Deposit date: 2002-12-21 Release date: 2003-01-07 Last modified: 2021-02-03 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Structure of the MesJ PP-ATPase from Escherichia coli To be Published
7MDO	Structure of human p97 ATPase L464P mutant Descriptor: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase Authors: Zhang, X, Gui, L, Li, S, Nandi, P, Columbres, R.C, Wong, D.E, Moen, D.R, Lin, H.J, Chiu, P.-L, Chou, T.-F. Deposit date: 2021-04-05 Release date: 2021-08-25 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (4.12 Å) Cite: Conserved L464 in p97 D1-D2 linker is critical for p97 cofactor regulated ATPase activity. Biochem.J., 478, 2021

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