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7TMQ
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BU of 7tmq by Molmil
V1 complex lacking subunit C from Saccharomyces cerevisiae, State 3
Descriptor: ADENOSINE-5'-DIPHOSPHATE, H(+)-transporting two-sector ATPase, MAGNESIUM ION, ...
Authors:Vasanthakumar, T, Keon, K.A, Bueler, S.A, Jaskolka, M.C, Rubinstein, J.L.
Deposit date:2022-01-19
Release date:2022-04-06
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Coordinated conformational changes in the V 1 complex during V-ATPase reversible dissociation.
Nat.Struct.Mol.Biol., 29, 2022
7TMP
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BU of 7tmp by Molmil
V1 complex lacking subunit C from Saccharomyces cerevisiae, State 2
Descriptor: ADENOSINE-5'-DIPHOSPHATE, H(+)-transporting two-sector ATPase, MAGNESIUM ION, ...
Authors:Vasanthakumar, T, Keon, K.A, Bueler, S.A, Jaskolka, M.C, Rubinstein, J.L.
Deposit date:2022-01-19
Release date:2022-04-06
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Coordinated conformational changes in the V 1 complex during V-ATPase reversible dissociation.
Nat.Struct.Mol.Biol., 29, 2022
7TMM
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BU of 7tmm by Molmil
Complete V1 Complex from Saccharomyces cerevisiae
Descriptor: ADENOSINE-5'-DIPHOSPHATE, H(+)-transporting two-sector ATPase, V-ATPase subunit E, ...
Authors:Vasanthakumar, T, Keon, K.A, Bueler, S.A, Jaskolka, M.C, Rubinstein, J.L.
Deposit date:2022-01-19
Release date:2022-04-06
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Coordinated conformational changes in the V 1 complex during V-ATPase reversible dissociation.
Nat.Struct.Mol.Biol., 29, 2022
7TMO
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BU of 7tmo by Molmil
V1 complex lacking subunit C from Saccharomyces cerevisiae, State 1
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, H(+)-transporting two-sector ATPase, ...
Authors:Vasanthakumar, T, Keon, K.A, Bueler, S.A, Jaskolka, M.C, Rubinstein, J.L.
Deposit date:2022-01-19
Release date:2022-04-06
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Coordinated conformational changes in the V 1 complex during V-ATPase reversible dissociation.
Nat.Struct.Mol.Biol., 29, 2022
7TMR
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BU of 7tmr by Molmil
V-ATPase from Saccharomyces cerevisiae, State 1
Descriptor: ADENOSINE-5'-DIPHOSPHATE, H(+)-transporting two-sector ATPase, V-type proton ATPase subunit C, ...
Authors:Vasanthakumar, T, Keon, K.A, Bueler, S.A, Jaskolka, M.C, Rubinstein, J.L.
Deposit date:2022-01-19
Release date:2022-04-13
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Coordinated conformational changes in the V 1 complex during V-ATPase reversible dissociation.
Nat.Struct.Mol.Biol., 29, 2022
7TYR
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BU of 7tyr by Molmil
Cryo-EM structure of the basal state of the Artemis:DNA-PKcs complex (see COMPND 13/14)
Descriptor: DNA-dependent protein kinase catalytic subunit, Protein artemis
Authors:Watanabe, G, Lieber, M.R, Williams, D.R.
Deposit date:2022-02-14
Release date:2022-07-20
Last modified:2022-08-03
Method:ELECTRON MICROSCOPY (3.33 Å)
Cite:Structural analysis of the basal state of the Artemis:DNA-PKcs complex.
Nucleic Acids Res., 50, 2022
2RP3
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BU of 2rp3 by Molmil
Solution Structure of Cyanovirin-N Domain B Mutant
Descriptor: Cyanovirin-N
Authors:Matei, E, Furey, W, Gronenborn, A.M.
Deposit date:2008-04-30
Release date:2008-08-19
Last modified:2021-11-10
Method:SOLUTION NMR
Cite:Solution and crystal structures of a sugar binding site mutant of cyanovirin-N: no evidence of domain swapping
Structure, 16, 2008
2U2A
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BU of 2u2a by Molmil
STEM LOOP IIA FROM U2 SNRNA OF SACCHAROMYCES CEREVISIAE, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: RNA (5'-R(P*GP*GP*UP*CP*AP*GP*UP*GP*UP*AP*AP*CP*AP*AP*CP*UP*GP*AP*CP*C)-3')
Authors:Stallings, S.C, Moore, P.B.
Deposit date:1997-08-20
Release date:1998-03-04
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The structure of an essential splicing element: stem loop IIa from yeast U2 snRNA.
Structure, 5, 1997
2WTI
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BU of 2wti by Molmil
CRYSTAL STRUCTURE OF CHK2 IN COMPLEX WITH AN INHIBITOR
Descriptor: 1,2-ETHANEDIOL, 4-[2-AMINO-5-(2,3-DIHYDROTHIENO[3,4-B][1,4]DIOXIN-5-YL)PYRIDIN-3-YL]BENZAMIDE, CHECKPOINT KINASE 2, ...
Authors:Hilton, S, Naud, S, Caldwell, J.J, Boxall, K, Burns, S, Anderson, V.E, Antoni, L, Allen, C.E, Pearl, L.H, Oliver, A.W, Aherne, G.W, Garrett, M.D, Collins, I.
Deposit date:2009-09-16
Release date:2009-12-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Identification and Characterisation of 2-Aminopyridine Inhibitors of Checkpoint Kinase 2
Bioorg.Med.Chem., 18, 2010
2VJF
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BU of 2vjf by Molmil
Crystal Structure of the MDM2-MDMX RING Domain Heterodimer
Descriptor: CITRATE ANION, E3 UBIQUITIN-PROTEIN LIGASE MDM2, MDM4 PROTEIN, ...
Authors:Mace, P.D, Linke, K, Smith, C.A, Day, C.L.
Deposit date:2007-12-10
Release date:2008-05-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the Mdm2/Mdmx Ring Domain Heterodimer Reveals Dimerization is Required for Their Ubiquitylation in Trans.
Cell Death Differ., 15, 2008
2WTJ
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BU of 2wtj by Molmil
CRYSTAL STRUCTURE OF CHK2 IN COMPLEX WITH AN INHIBITOR
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-5-(2,3-DIHYDROTHIENO[3,4-B][1,4]DIOXIN-5-YL)-N-[2-(DIMETHYLAMINO)ETHYL]PYRIDINE-3-CARBOXAMIDE, CHECKPOINT KINASE 2, ...
Authors:Hilton, S, Naud, S, Caldwell, J.J, Boxall, K, Burns, S, Anderson, V.E, Antoni, L, Allen, C.E, Pearl, L.H, Oliver, A.W, Aherne, G.W, Garrett, M.D, Collins, I.
Deposit date:2009-09-16
Release date:2009-12-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Identification and Characterisation of 2-Aminopyridine Inhibitors of Checkpoint Kinase 2
Bioorg.Med.Chem., 18, 2010
2VJE
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BU of 2vje by Molmil
Crystal Structure of the MDM2-MDMX RING Domain Heterodimer
Descriptor: CITRATE ANION, E3 UBIQUITIN-PROTEIN LIGASE MDM2, MDM4 PROTEIN, ...
Authors:Mace, P.D, Linke, K, Smith, C.A, Day, C.L.
Deposit date:2007-12-10
Release date:2008-05-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the MDM2/MDMX RING domain heterodimer reveals dimerization is required for their ubiquitylation in trans.
Cell Death Differ., 15, 2008
2XVS
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BU of 2xvs by Molmil
Crystal structure of human TTC5 (Strap) C-terminal OB domain
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, IODIDE ION, ...
Authors:Adams, J, Pike, A.C.W, Maniam, S, Sharpe, T.D, Coutts, A.S, Knapp, S, La Thangue, B, Bullock, A.N.
Deposit date:2010-10-31
Release date:2010-11-17
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The P53 Cofactor Strap Exhibits an Unexpected Tpr Motif and Oligonucleotide-Binding (Ob)-Fold Structure.
Proc.Natl.Acad.Sci.USA, 109, 2012
3UMZ
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BU of 3umz by Molmil
Crystal Structure of the human MDC1 FHA Domain
Descriptor: Mediator of DNA damage checkpoint protein 1
Authors:Luo, S, Ye, K.
Deposit date:2011-11-15
Release date:2012-01-25
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural mechanism of the phosphorylation-dependent dimerization of the MDC1 forkhead-associated domain
Nucleic Acids Res., 40, 2012
3UNM
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BU of 3unm by Molmil
Crystal Structure of The Human MDC1 FHA Domain
Descriptor: Mediator of DNA damage checkpoint protein 1
Authors:Luo, S, Ye, K.
Deposit date:2011-11-16
Release date:2012-01-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural mechanism of the phosphorylation-dependent dimerization of the MDC1 forkhead-associated domain
Nucleic Acids Res., 40, 2012
3VA4
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BU of 3va4 by Molmil
Crystal structure of the mammalian MDC1 FHA domain complexed with CHK2 pThr68 peptide
Descriptor: Mediator of DNA damage checkpoint protein 1, Serine/threonine-protein kinase Chk2
Authors:Wu, H.H, Wu, P.Y, Huang, K.F, Kao, Y.Y, Tsai, M.D.
Deposit date:2011-12-28
Release date:2012-02-01
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Structural Delineation of MDC1-FHA Domain Binding with CHK2-pThr68.
Biochemistry, 2012
4AXP
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BU of 4axp by Molmil
NMR structure of Hsp12, a protein induced by and required for dietary restriction-induced lifespan extension in yeast.
Descriptor: 12 KDA HEAT SHOCK PROTEIN
Authors:Herbert, A.P, Riesen, M, Bloxam, L, Kosmidou, E, Wareing, B.M, Johnson, J.R, Phelan, M.M, Pennington, S.R, Lian, L.Y, Morgan, A.
Deposit date:2012-06-13
Release date:2012-08-08
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NMR Structure of Hsp12, a Protein Induced by and Required for Dietary Restriction-Induced Lifespan Extension in Yeast.
Plos One, 7, 2012
7DH3
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BU of 7dh3 by Molmil
The co-crystal structure of DYRK2 with a small molecule inhibitor 5
Descriptor: 2,7-dimethoxy-9-piperidin-4-ylsulfanyl-acridine, Dual specificity tyrosine-phosphorylation-regulated kinase 2
Authors:Wei, T, Xiao, J.
Deposit date:2020-11-12
Release date:2021-11-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:The co-crystal structure of DYRK2 with a small molecule inhibitor 5
To Be Published
7FDA
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BU of 7fda by Molmil
CryoEM Structure of Reconstituted V-ATPase, state1
Descriptor: Fusion of yeast V-type proton ATPase subunit H(NT) and human V-type proton ATPase subunit H(CT), V-type proton ATPase subunit B, V-type proton ATPase subunit C, ...
Authors:Khan, M.M, Lee, S, Oot, R.A, Couoh-Cardel, S, KIm, H, Wilkens, S, Roh, S.H.
Deposit date:2021-07-16
Release date:2021-12-22
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:CryoEM Structures of Reconstituted V-ATPase and Oxr1-bound V1 Reveal a Novel Mechanism of Regulation.
Embo J., 2021
7FDC
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BU of 7fdc by Molmil
CryoEM Structures of Reconstituted V-ATPase, state3
Descriptor: Fusion of yeast V-type proton ATPase subunit H(NT) and human V-type proton ATPase subunit H(CT), V-type proton ATPase subunit B, V-type proton ATPase subunit C, ...
Authors:Khan, M.M, Lee, S, Oot, R.A, Couoh-Cardel, S, KIm, H, Wilkens, S, Roh, S.H.
Deposit date:2021-07-16
Release date:2021-12-22
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:CryoEM Structures of Reconstituted V-ATPase and Oxr1-bound V1 Reveal a Novel Mechanism of Regulation.
Embo J., 2021
7FDB
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BU of 7fdb by Molmil
CryoEM Structures of Reconstituted V-ATPase,State2
Descriptor: Fusion of yeast V-type proton ATPase subunit H(NT) and human V-type proton ATPase subunit H(CT), V-type proton ATPase subunit B, V-type proton ATPase subunit C, ...
Authors:Khan, M.M, Lee, S, Oot, R.A, Couoh-Cardel, S, KIm, H, Wilkens, S, Roh, S.H.
Deposit date:2021-07-16
Release date:2021-12-22
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:CryoEM Structures of Reconstituted V-ATPase and Oxr1-bound V1 Reveal a Novel Mechanism of Regulation.
Embo J., 2021
7FDE
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BU of 7fde by Molmil
CryoEM Structures of Reconstituted V-ATPase, Oxr1 bound V1
Descriptor: Oxidation resistance protein 1, V-type proton ATPase subunit B, V-type proton ATPase subunit C, ...
Authors:Khan, M.M, Lee, S, Oot, R.A, Couoh-Cardel, S, KIm, H, Wilkens, S, Roh, S.H.
Deposit date:2021-07-16
Release date:2021-12-29
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:CryoEM Structures of Reconstituted V-ATPase and Oxr1-bound V1 Reveal a Novel Mechanism of Regulation.
Embo J., 2021
6KE6
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BU of 6ke6 by Molmil
3.4 angstrom cryo-EM structure of yeast 90S small subunit preribosome
Descriptor: 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ...
Authors:Du, Y, Ye, K, An, W.
Deposit date:2019-07-03
Release date:2020-08-05
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:3.4 angstrom cryo-EM structure of yeast 90S small subunit preribosome
To be published
6KJ1
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BU of 6kj1 by Molmil
200kV MicroED structure of FUS (37-42) SYSGYS solved from merged datasets at 0.65 A
Descriptor: RNA-binding protein FUS
Authors:Zhou, H, Luo, F, Luo, Z, Li, D, Liu, C, Li, X.
Deposit date:2019-07-20
Release date:2019-10-02
Last modified:2024-03-27
Method:ELECTRON CRYSTALLOGRAPHY (0.65 Å)
Cite:Programming Conventional Electron Microscopes for Solving Ultrahigh-Resolution Structures of Small and Macro-Molecules.
Anal.Chem., 91, 2019
6V2F
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BU of 6v2f by Molmil
Crystal structure of the HIV capsid hexamer bound to the small molecule long-acting inhibitor, GS-6207
Descriptor: HIV-1 capsid, N-[(1S)-1-(3-{4-chloro-3-[(methylsulfonyl)amino]-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl}-6-[3-methyl-3-(methylsulfonyl)but-1-yn-1-yl]pyridin-2-yl)-2-(3,5-difluorophenyl)ethyl]-2-[(3bS,4aR)-5,5-difluoro-3-(trifluoromethyl)-3b,4,4a,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl]acetamide
Authors:Appleby, T.C, Link, J.O, Yant, S.R, Villasenor, A.G, Somoza, J.R, Hu, E.Y, Schroeder, S.D, Cihlar, T.
Deposit date:2019-11-22
Release date:2020-07-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Clinical targeting of HIV capsid protein with a long-acting small molecule.
Nature, 584, 2020

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数据于2024-08-14公开中

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