2XVS

Crystal structure of human TTC5 (Strap) C-terminal OB domain

Summary for 2XVS

• Entry DOI: 10.2210/pdb2xvs/pdb
• Descriptor: TETRATRICOPEPTIDE REPEAT PROTEIN 5, IODIDE ION, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: antitumor protein, p53 cofactor, stress-response, p300
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Nucleus: Q8N0Z6
• Total number of polymer chains: 1
• Total formula weight: 18660.26

Authors

Adams, J.,Pike, A.C.W.,Maniam, S.,Sharpe, T.D.,Coutts, A.S.,Knapp, S.,La Thangue, B.,Bullock, A.N. (deposition date: 2010-10-31, release date: 2010-11-17, Last modification date: 2012-03-21)

• Primary citation: Adams, C.J.,Pike, A.C.,Maniam, S.,Sharpe, T.D.,Coutts, A.S.,Knapp, S.,La Thangue, N.B.,Bullock, A.N.; The P53 Cofactor Strap Exhibits an Unexpected Tpr Motif and Oligonucleotide-Binding (Ob)-Fold Structure.; Proc.Natl.Acad.Sci.USA, 109:3778-, 2012; PubMed: 22362889; DOI: 10.1073/PNAS.1113731109

Experimental method

X-RAY DIFFRACTION (1.8 Å)