1XJI
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![BU of 1xji by Molmil](/molmil-images/mine/1xji) | Bacteriorhodopsin crystallized in bicelles at room temperature | Descriptor: | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Bacteriorhodopsin, DECANE, ... | Authors: | Faham, S, Boulting, G.L, Massey, E.A, Yohannan, S, Yang, D, Bowie, J.U. | Deposit date: | 2004-09-23 | Release date: | 2005-04-19 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystallization of bacteriorhodopsin from bicelle formulations at room temperature Protein Sci., 14, 2005
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2CN0
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![BU of 2cn0 by Molmil](/molmil-images/mine/2cn0) | Complex of Recombinant Human Thrombin with a Designed Inhibitor | Descriptor: | 4-(1R,3AS,4R,8AS,8BR)-[1-DIFLUOROMETHYL-2-(4-FLUOROBENZYL)-3-OXODECAHYDROPYRROLO[3,4-A]PYRROLIZIN-4-YL]BENZAMIDINE, CALCIUM ION, HIRUDIN IIA, ... | Authors: | Hoffmann-Roder, A, Schweizer, E, Egger, J, Seiler, P, Obst-Sander, U, Wagner, B, Kansy, M, Banner, D.W, Diederich, F. | Deposit date: | 2006-05-17 | Release date: | 2006-11-06 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Mapping the Fluorophilicity of a Hydrophobic Pocket: Synthesis and Biological Evaluation of Tricyclic Thrombin Inhibitors Directing Fluorinated Alkyl Groups Into the P Pocket Chemmedchem, 1, 2006
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2CQU
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![BU of 2cqu by Molmil](/molmil-images/mine/2cqu) | Solution Structure of RSGI RUH-045, a Human Acyl-CoA Binding Protein | Descriptor: | peroxisomal D3,D2-enoyl-CoA isomerase | Authors: | Tsubota, Y, Ruhul Momen, A.Z.M, Onuki, H, Hirota, H, Saito, K, Koshiba, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-05-20 | Release date: | 2005-11-20 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution Structure of RSGI RUH-045, a Human Acyl-CoA Binding Protein To be Published
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1XME
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![BU of 1xme by Molmil](/molmil-images/mine/1xme) | Structure of Recombinant Cytochrome ba3 Oxidase from Thermus thermophilus | Descriptor: | COPPER (II) ION, Cytochrome c oxidase polypeptide I, Cytochrome c oxidase polypeptide II, ... | Authors: | Hunsicker-Wang, L.M, Pacoma, R.L, Chen, Y, Fee, J.A, Stout, C.D. | Deposit date: | 2004-10-01 | Release date: | 2005-03-22 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A novel cryoprotection scheme for enhancing the diffraction of crystals of recombinant cytochrome ba3 oxidase from Thermus thermophilus. Acta Crystallogr.,Sect.D, 61, 2005
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1Z4K
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![BU of 1z4k by Molmil](/molmil-images/mine/1z4k) | Structure of the D41N variant of the human mitochondrial deoxyribonucleotidase in complex with thymidine 3'-monophosphate | Descriptor: | 5'(3')-deoxyribonucleotidase, MAGNESIUM ION, THYMIDINE-3'-PHOSPHATE | Authors: | Wallden, K, Ruzzenente, B, Rinaldo-Matthis, A, Bianchi, V, Nordlund, P. | Deposit date: | 2005-03-16 | Release date: | 2005-07-26 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural basis for substrate specificity of the human mitochondrial deoxyribonucleotidase STRUCTURE, 13, 2005
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1XPG
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![BU of 1xpg by Molmil](/molmil-images/mine/1xpg) | Crystal Structure of T. maritima Cobalamin-Independent Methionine Synthase complexed with Zn2+ and Methyltetrahydrofolate | Descriptor: | 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, MESO-ERYTHRITOL, ... | Authors: | Pejchal, R, Ludwig, M.L. | Deposit date: | 2004-10-08 | Release date: | 2005-03-01 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Cobalamin-independent methionine synthase (MetE): a face-to-face double barrel that evolved by gene duplication Plos Biol., 3, 2005
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1XMM
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![BU of 1xmm by Molmil](/molmil-images/mine/1xmm) | Structure of human Dcps bound to m7GDP | Descriptor: | 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, N7-METHYL-GUANOSINE-5'-MONOPHOSPHATE, PHOSPHATE ION, ... | Authors: | Chen, N, Song, H. | Deposit date: | 2004-10-04 | Release date: | 2005-03-22 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structures of human DcpS in ligand-free and m7GDP-bound forms suggest a dynamic mechanism for scavenger mRNA decapping. J.Mol.Biol., 347, 2005
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1XQ0
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![BU of 1xq0 by Molmil](/molmil-images/mine/1xq0) | Structure of human carbonic anhydrase II with 4-[(3-bromo-4-O-sulfamoylbenzyl)(4-cyanophenyl)amino]-4H-[1,2,4]-triazole | Descriptor: | 2-BROMO-4-{[(4-CYANOPHENYL)(4H-1,2,4-TRIAZOL-4-YL)AMINO]METHYL}PHENYL SULFAMATE, Carbonic anhydrase II, ZINC ION | Authors: | Lloyd, M.D, Thiyagarajan, N, Ho, Y.T, Woo, L.W.L, Sutcliffe, O.B, Purohit, A, Reed, M.J, Acharya, K.R, Potter, B.V.L. | Deposit date: | 2004-10-11 | Release date: | 2005-05-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | First Crystal Structures of Human Carbonic Anhydrase II in Complex with Dual Aromatase-Steroid Sulfatase Inhibitors(,) Biochemistry, 44, 2005
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1Z93
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![BU of 1z93 by Molmil](/molmil-images/mine/1z93) | Human Carbonic Anhydrase III:Structural and Kinetic study of Catalysis and Proton Transfer. | Descriptor: | Carbonic anhydrase III, ZINC ION | Authors: | Duda, D.M, Tu, C, Fisher, S.Z, An, H, Yoshioka, C, Govindasamy, L, Laipis, P.J, Agbandje-McKenna, M, Silverman, D.N, McKenna, R. | Deposit date: | 2005-03-31 | Release date: | 2005-08-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Human Carbonic Anhydrase III: Structural and Kinetic Study of Catalysis and Proton Transfer Biochemistry, 44, 2005
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1ZC9
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![BU of 1zc9 by Molmil](/molmil-images/mine/1zc9) | The crystal structure of dialkylglycine decarboxylase complex with pyridoxamine 5-phosphate | Descriptor: | 2,2-dialkylglycine decarboxylase, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, POTASSIUM ION, ... | Authors: | Fogle, E.J, Liu, W, Toney, M.D. | Deposit date: | 2005-04-11 | Release date: | 2006-01-03 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Role of q52 in catalysis of decarboxylation and transamination in dialkylglycine decarboxylase. Biochemistry, 44, 2005
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1XYP
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![BU of 1xyp by Molmil](/molmil-images/mine/1xyp) | |
1XW6
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![BU of 1xw6 by Molmil](/molmil-images/mine/1xw6) | 1.9 angstrom resolution structure of human glutathione S-transferase M1A-1A complexed with glutathione | Descriptor: | GLUTATHIONE, Glutathione S-transferase Mu 1 | Authors: | Patskovsky, Y, Patskovska, L, Almo, S.C, Listowsky, I. | Deposit date: | 2004-10-29 | Release date: | 2004-12-21 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Transition state model and mechanism of nucleophilic aromatic substitution reactions catalyzed by human glutathione S-transferase M1a-1a. Biochemistry, 45, 2006
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1XG7
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![BU of 1xg7 by Molmil](/molmil-images/mine/1xg7) | Conserved hypothetical protein Pfu-877259-001 from Pyrococcus furiosus | Descriptor: | hypothetical protein | Authors: | Chang, J, Zhao, M, Horanyi, P, Xu, H, Yang, H, Liu, Z.-J, Chen, L, Zhou, W, Habel, J, Tempel, W, Lee, D, Lin, D, Chang, S.-H, Eneh, J.C, Hopkins, R.C, Jenney Jr, F.E, Lee, H.-S, Li, T, Poole II, F.L, Shah, C, Sugar, F.J, Chen, C.-Y, Arendall III, W.B, Richardson, J.S, Richardson, D.C, Rose, J.P, Adams, M.W.W, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG) | Deposit date: | 2004-09-16 | Release date: | 2004-11-23 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Conserved hypothetical protein Pfu-877259-001 from Pyrococcus furiosus To be published
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1XH4
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![BU of 1xh4 by Molmil](/molmil-images/mine/1xh4) | Crystal Structures of Protein Kinase B Selective Inhibitors in Complex with Protein Kinase A and Mutants | Descriptor: | N-[4-({4-[5-(DIMETHYLAMINO)-2-HYDROXYBENZOYL]BENZOYL}AMINO)AZEPAN-3-YL]ISONICOTINAMIDE, cAMP-dependent protein kinase inhibitor, alpha form, ... | Authors: | Breitenlechner, C.B, Friebe, W.-G, Brunet, E, Werner, G, Graul, K, Thomas, U, Kuenkele, K.-P, Schaefer, W, Gassel, M, Bossemeyer, D, Huber, R, Engh, R.A, Masjost, B. | Deposit date: | 2004-09-17 | Release date: | 2005-09-17 | Last modified: | 2024-06-26 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Design and crystal structures of protein kinase B-selective inhibitors in complex with protein kinase A and mutants J.Med.Chem., 48, 2005
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1ZJ2
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![BU of 1zj2 by Molmil](/molmil-images/mine/1zj2) | Crystal Structure of Human Galactosyltransferase (GTB) Complexed with H type I Trisaccharide | Descriptor: | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase), ... | Authors: | Letts, J.A, Rose, N.L, Fang, Y.R, Barry, C.H, Borisova, S.N, Seto, N.O, Palcic, M.M, Evans, S.V. | Deposit date: | 2005-04-27 | Release date: | 2005-12-13 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Differential Recognition of the Type I and II H Antigen Acceptors by the Human ABO(H) Blood Group A and B Glycosyltransferases. J.Biol.Chem., 281, 2006
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1Z4P
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![BU of 1z4p by Molmil](/molmil-images/mine/1z4p) | Structure of the D41N variant of the human mitochondrial deoxyribonucleotidase in complex with deoxyriboguanosine 5'-monophosphate | Descriptor: | 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, 5'(3')-deoxyribonucleotidase, MAGNESIUM ION | Authors: | Wallden, K, Ruzzenente, B, Rinaldo-Matthis, A, Bianchi, V, Nordlund, P. | Deposit date: | 2005-03-16 | Release date: | 2005-07-26 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for substrate specificity of the human mitochondrial deoxyribonucleotidase STRUCTURE, 13, 2005
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1ZOB
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![BU of 1zob by Molmil](/molmil-images/mine/1zob) | |
1XH7
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![BU of 1xh7 by Molmil](/molmil-images/mine/1xh7) | Crystal Structures of Protein Kinase B Selective Inhibitors in Complex with Protein Kinase A and Mutants | Descriptor: | N-[4-({4-[5-(3,3-DIMETHYLPIPERIDIN-1-YL)-2-HYDROXYBENZOYL]BENZOYL}AMINO)AZEPAN-3-YL]ISONICOTINAMIDE, cAMP-dependent protein kinase inhibitor, alpha form, ... | Authors: | Breitenlechner, C.B, Friebe, W.-G, Brunet, E, Werner, G, Graul, K, Thomas, U, Kuenkele, K.-P, Schaefer, W, Gassel, M, Bossemeyer, D, Huber, R, Engh, R.A, Masjost, B. | Deposit date: | 2004-09-17 | Release date: | 2005-09-17 | Last modified: | 2024-06-26 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Design and crystal structures of protein kinase B-selective inhibitors in complex with protein kinase A and mutants J.Med.Chem., 48, 2005
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1ZAL
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![BU of 1zal by Molmil](/molmil-images/mine/1zal) | Fructose-1,6-bisphosphate aldolase from rabbit muscle in complex with partially disordered tagatose-1,6-bisphosphate, a weak competitive inhibitor | Descriptor: | Fructose-bisphosphate aldolase A, PHOSPHATE ION | Authors: | St-Jean, M, Lafrance-Vanasse, J, Liotard, B, Sygusch, J. | Deposit date: | 2005-04-06 | Release date: | 2005-05-10 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | High Resolution Reaction Intermediates of Rabbit Muscle Fructose-1,6-bisphosphate Aldolase: substrate cleavage and induced fit. J.Biol.Chem., 280, 2005
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1XNS
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![BU of 1xns by Molmil](/molmil-images/mine/1xns) | Peptide trapped Holliday junction intermediate in Cre-loxP recombination | Descriptor: | Recombinase CRE, loxP DNA | Authors: | Ghosh, K, Lau, C.K, Guo, F, Segall, A.M, Van Duyne, G.D. | Deposit date: | 2004-10-05 | Release date: | 2004-12-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Peptide trapping of the Holliday junction intermediate in Cre-loxP site-specific recombination. J.Biol.Chem., 280, 2005
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1ZI5
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![BU of 1zi5 by Molmil](/molmil-images/mine/1zi5) | Crystal Structure of Human N-acetylgalactosaminyltransferase (GTA) Complexed with H type I Trisaccharide | Descriptor: | Histo-blood group ABO system transferase (NAGAT) Includes: Glycoprotein-fucosylgalactoside alpha-N- acetylgalactosaminyltransferase, MERCURY (II) ION, URIDINE-5'-DIPHOSPHATE, ... | Authors: | Letts, J.A, Rose, N.L, Fang, Y.R, Barry, C.H, Borisova, S.N, Seto, N.O, Palcic, M.M, Evans, S.V. | Deposit date: | 2005-04-26 | Release date: | 2005-12-13 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Differential Recognition of the Type I and II H Antigen Acceptors by the Human ABO(H) Blood Group A and B Glycosyltransferases. J.Biol.Chem., 281, 2006
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1XXP
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![BU of 1xxp by Molmil](/molmil-images/mine/1xxp) | Yersinia YopH (residues 163-468) C403S binds phosphotyrosyl peptide at two sites | Descriptor: | Hexapeptide ASP-ALA-ASP-GLU-PTR-CLE, Protein-tyrosine phosphatase yopH | Authors: | Ivanov, M.I, Stuckey, J.A, Schubert, H.L, Saper, M.A, Bliska, J.B. | Deposit date: | 2004-11-07 | Release date: | 2005-03-22 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Two substrate-targeting sites in the Yersinia protein tyrosine phosphatase co-operate to promote bacterial virulence Mol.Microbiol., 55, 2005
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1XA8
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![BU of 1xa8 by Molmil](/molmil-images/mine/1xa8) | Crystal Structure Analysis of Glutathione-dependent formaldehyde-activating enzyme (Gfa) | Descriptor: | GLUTATHIONE, GLYCEROL, Glutathione-dependent formaldehyde-activating enzyme, ... | Authors: | Neculai, A.M, Neculai, D, Griesinger, C, Vorholt, J.A, Becker, S. | Deposit date: | 2004-08-25 | Release date: | 2004-11-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A dynamic zinc redox switch J.Biol.Chem., 280, 2005
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1XYO
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![BU of 1xyo by Molmil](/molmil-images/mine/1xyo) | |
2AR7
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![BU of 2ar7 by Molmil](/molmil-images/mine/2ar7) | Crystal structure of human adenylate kinase 4, AK4 | Descriptor: | Adenylate kinase 4 | Authors: | Filippakopoulos, P, Turnbull, A.P, Fedorov, O, Weigelt, J, Bunkoczi, G, Ugochukwu, E, Debreczeni, J, Niesen, F, von Delft, F, Edwards, A, Arrowsmith, C, Sundstrom, M, Structural Genomics Consortium (SGC) | Deposit date: | 2005-08-19 | Release date: | 2005-12-06 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal structure of human adenylate kinase 4, AK4 To be Published
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