8BL7
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![BU of 8bl7 by Molmil](/molmil-images/mine/8bl7) | |
8BLD
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![BU of 8bld by Molmil](/molmil-images/mine/8bld) | |
8BMO
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![BU of 8bmo by Molmil](/molmil-images/mine/8bmo) | Structure of GroEL:GroES complex exhibiting ADP-conformation in trans ring obtained under the continuous turnover conditions | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Chaperonin GroEL, Co-chaperonin GroES, ... | Authors: | Dhurandhar, M, Torino, S, Efremov, R. | Deposit date: | 2022-11-10 | Release date: | 2023-08-09 | Last modified: | 2023-09-13 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Time-resolved cryo-EM using a combination of droplet microfluidics with on-demand jetting. Nat.Methods, 20, 2023
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8BLY
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![BU of 8bly by Molmil](/molmil-images/mine/8bly) | |
8BKA
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![BU of 8bka by Molmil](/molmil-images/mine/8bka) | |
8BKZ
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![BU of 8bkz by Molmil](/molmil-images/mine/8bkz) | GroEL:GroES-ATP complex under continuous turnover conditions | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Chaperonin GroEL, Co-chaperonin GroES, ... | Authors: | Dhurandhar, M, Torino, S, Efremov, R. | Deposit date: | 2022-11-09 | Release date: | 2023-08-09 | Last modified: | 2023-09-13 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | Time-resolved cryo-EM using a combination of droplet microfluidics with on-demand jetting. Nat.Methods, 20, 2023
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8BLE
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![BU of 8ble by Molmil](/molmil-images/mine/8ble) | |
8BM1
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![BU of 8bm1 by Molmil](/molmil-images/mine/8bm1) | Structure of GroEL:GroES-ATP complex under continuous turnover conditions | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Chaperonin GroEL, Co-chaperonin GroES, ... | Authors: | Dhurandhar, M, Torino, S, Efremov, R. | Deposit date: | 2022-11-10 | Release date: | 2023-08-09 | Last modified: | 2023-09-13 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Time-resolved cryo-EM using a combination of droplet microfluidics with on-demand jetting. Nat.Methods, 20, 2023
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8BL2
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![BU of 8bl2 by Molmil](/molmil-images/mine/8bl2) | Structure of GroEL-ATP complex plunge frozen 200 ms after reaction initiation | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Chaperonin GroEL, MAGNESIUM ION, ... | Authors: | Dhurandhar, M, Torino, S, Efremov, R. | Deposit date: | 2022-11-09 | Release date: | 2023-08-09 | Last modified: | 2023-09-13 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | Time-resolved cryo-EM using a combination of droplet microfluidics with on-demand jetting. Nat.Methods, 20, 2023
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8BK7
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![BU of 8bk7 by Molmil](/molmil-images/mine/8bk7) | |
8BKG
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![BU of 8bkg by Molmil](/molmil-images/mine/8bkg) | |
8BLF
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![BU of 8blf by Molmil](/molmil-images/mine/8blf) | |
8BMT
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![BU of 8bmt by Molmil](/molmil-images/mine/8bmt) | Structure of GroEL:GroES-ATP complex plunge frozen 200 ms after reaction initiation | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Chaperonin GroEL, Co-chaperonin GroES, ... | Authors: | Dhurandhar, M, Efremov, R, Torino, S. | Deposit date: | 2022-11-10 | Release date: | 2023-08-09 | Last modified: | 2023-09-13 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Time-resolved cryo-EM using a combination of droplet microfluidics with on-demand jetting. Nat.Methods, 20, 2023
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8BK8
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![BU of 8bk8 by Molmil](/molmil-images/mine/8bk8) | |
8BLC
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![BU of 8blc by Molmil](/molmil-images/mine/8blc) | Structure of the GroEL-ATP complex plunge-frozen 50 ms after mixing with ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Chaperonin GroEL, MAGNESIUM ION, ... | Authors: | Dhurandhar, M, Torino, S, Efremov, R. | Deposit date: | 2022-11-09 | Release date: | 2023-08-09 | Last modified: | 2023-09-13 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Time-resolved cryo-EM using a combination of droplet microfluidics with on-demand jetting. Nat.Methods, 20, 2023
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8BMD
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![BU of 8bmd by Molmil](/molmil-images/mine/8bmd) | Structure of GroEL-ATP complex under continuous turnover conditions | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Chaperonin GroEL, MAGNESIUM ION, ... | Authors: | Dhurandhar, M, Torino, S, Efremov, R. | Deposit date: | 2022-11-10 | Release date: | 2023-08-09 | Last modified: | 2023-09-13 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Time-resolved cryo-EM using a combination of droplet microfluidics with on-demand jetting. Nat.Methods, 20, 2023
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8B5K
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![BU of 8b5k by Molmil](/molmil-images/mine/8b5k) | Structure of haloalkane dehalogenase DmmarA from Mycobacterium marinum at pH 6.5 | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FORMIC ACID, ... | Authors: | Snajdarova, K, Marek, M. | Deposit date: | 2022-09-23 | Release date: | 2023-08-30 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.849 Å) | Cite: | Atypical homodimerization revealed by the structure of the (S)-enantioselective haloalkane dehalogenase DmmarA from Mycobacterium marinum. Acta Crystallogr D Struct Biol, 79, 2023
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8B5O
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8BBK
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8BUM
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![BU of 8bum by Molmil](/molmil-images/mine/8bum) | Structure of DDB1 bound to DS15-engaged CDK12-cyclin K | Descriptor: | (2R)-2-[[6-(5-naphthalen-1-ylpentylamino)-9-propan-2-yl-purin-2-yl]amino]butan-1-ol, Cyclin-K, Cyclin-dependent kinase 12, ... | Authors: | Kozicka, Z, Kempf, G, Petzold, G, Thoma, N.H. | Deposit date: | 2022-11-30 | Release date: | 2023-09-20 | Last modified: | 2024-01-03 | Method: | X-RAY DIFFRACTION (3.36 Å) | Cite: | Design principles for cyclin K molecular glue degraders. Nat.Chem.Biol., 20, 2024
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8BBQ
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![BU of 8bbq by Molmil](/molmil-images/mine/8bbq) | Determination of the structure of active tyrosinase from bacterium Verrucomicrobium spinosum | Descriptor: | COPPER (II) ION, Core tyrosinase, GLYCEROL, ... | Authors: | Fekry, M, Dave, K, Badgujar, D, Aurelius, O, Hamnevik, E, Dobritzsch, D, Danielson, H. | Deposit date: | 2022-10-14 | Release date: | 2023-09-20 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | The Crystal Structure of Tyrosinase from Verrucomicrobium spinosum Reveals It to Be an Atypical Bacterial Tyrosinase. Biomolecules, 13, 2023
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8BN8
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![BU of 8bn8 by Molmil](/molmil-images/mine/8bn8) | METTL3-METTL14 heterodimer bound to the SAM competitive small molecule inhibitor STM3006 | Descriptor: | 2-[[4-(6-bromanyl-2~{H}-indazol-4-yl)-1,2,3-triazol-1-yl]methyl]-6-[(4,4-dimethylpiperidin-1-yl)methyl]imidazo[1,2-a]pyridine, N6-adenosine-methyltransferase catalytic subunit, N6-adenosine-methyltransferase non-catalytic subunit | Authors: | Pilka, E.S, Thomas, B, Blackaby, W, Hardick, D, Feeney, K, Ridgill, M, Rotty, B, Rausch, O. | Deposit date: | 2022-11-13 | Release date: | 2023-09-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.213 Å) | Cite: | Inhibition of METTL3 Results in a Cell-Intrinsic Interferon Response That Enhances Antitumor Immunity. Cancer Discov, 13, 2023
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8BBR
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![BU of 8bbr by Molmil](/molmil-images/mine/8bbr) | Determination of the structure of active tyrosinase from bacterium Verrucomicrobium spinosum | Descriptor: | COPPER (II) ION, Core tyrosinase, SULFATE ION | Authors: | Fekry, M, Dave, K, Badgujar, D, Aurelius, O, Hamnevik, E, Dobritzsch, D, Danielson, H. | Deposit date: | 2022-10-14 | Release date: | 2023-09-20 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | The Crystal Structure of Tyrosinase from Verrucomicrobium spinosum Reveals It to Be an Atypical Bacterial Tyrosinase. Biomolecules, 13, 2023
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8BU7
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![BU of 8bu7 by Molmil](/molmil-images/mine/8bu7) | Structure of DDB1 bound to 21195-engaged CDK12-cyclin K | Descriptor: | 1,2-ETHANEDIOL, 1-[2,6-bis(chloranyl)phenyl]-6-[[4-(2-hydroxyethyloxy)phenyl]methyl]-3-propan-2-yl-5H-pyrazolo[3,4-d]pyrimidin-4-one, Cyclin-K, ... | Authors: | Kozicka, Z, Kempf, G, Petzold, G, Thoma, N.H. | Deposit date: | 2022-11-30 | Release date: | 2023-09-13 | Last modified: | 2024-01-03 | Method: | X-RAY DIFFRACTION (3.245 Å) | Cite: | Design principles for cyclin K molecular glue degraders. Nat.Chem.Biol., 20, 2024
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8BUN
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![BU of 8bun by Molmil](/molmil-images/mine/8bun) | Structure of DDB1 bound to DS16-engaged CDK12-cyclin K | Descriptor: | (2~{R})-2-[[6-[(4-phenylphenyl)methylamino]-9-propan-2-yl-purin-2-yl]amino]butan-1-ol, Cyclin-K, Cyclin-dependent kinase 12, ... | Authors: | Kozicka, Z, Kempf, G, Petzold, G, Thoma, N.H. | Deposit date: | 2022-11-30 | Release date: | 2023-09-13 | Last modified: | 2024-01-03 | Method: | X-RAY DIFFRACTION (3.08 Å) | Cite: | Design principles for cyclin K molecular glue degraders. Nat.Chem.Biol., 20, 2024
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