8BBK

Crystal structure of human Sirt3 in complex with a fragment of the human AROS protein

Summary for 8BBK

• Entry DOI: 10.2210/pdb8bbk/pdb
• Descriptor: NAD-dependent protein deacetylase sirtuin-3, mitochondrial, Active regulator of SIRT1, ZINC ION (3 entities in total)
• Functional Keywords: sirtuin 3, peptide complex, aros, inhibitor, hydrolase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 12
• Total formula weight: 354974.03

Authors

Steegborn, C.,Weiss, S. (deposition date: 2022-10-13, release date: 2023-08-30)

• Primary citation: Weiss, S.,Adolph, R.S.,Schweimer, K.,DiFonzo, A.,Meleshin, M.,Schutkowski, M.,Steegborn, C.; Molecular Mechanism of Sirtuin 1 Modulation by the AROS Protein.; Int J Mol Sci, 23:-, 2022; PubMed: 36361557; DOI: 10.3390/ijms232112764

Experimental method

X-RAY DIFFRACTION (3.27 Å)