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6XC3	Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies CC12.1 and CR3022 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CC12.1 heavy chain, CC12.1 light chain, ... Authors: Yuan, M, Liu, H, Wu, N.C, Zhu, X, Wilson, I.A. Deposit date: 2020-06-08 Release date: 2020-07-08 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.698 Å) Cite: Structural basis of a shared antibody response to SARS-CoV-2. Science, 369, 2020
6XC7	Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies CC12.3 and CR3022 Descriptor: CC12.3 heavy chain, CC12.3 light chain, CR3022 heavy chain, ... Authors: Yuan, M, Liu, H, Wu, N.C, Zhu, X, Wilson, I.A. Deposit date: 2020-06-08 Release date: 2020-07-08 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.883 Å) Cite: Structural basis of a shared antibody response to SARS-CoV-2. Science, 369, 2020
7K8X	Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C121 (State 1) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, C121 Fab Heavy chain, C121 Fab Light chain, ... Authors: Abernathy, M.E, Barnes, C.O, Bjorkman, P.J. Deposit date: 2020-09-27 Release date: 2020-10-21 Last modified: 2021-01-13 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies. Nature, 588, 2020
7K8Y	Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C121 (State 2) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, C121 Fab Heavy chain, C121 Fab Light chain, ... Authors: Abernathy, M.E, Barnes, C.O, Bjorkman, P.J. Deposit date: 2020-09-27 Release date: 2020-10-21 Last modified: 2021-01-13 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies. Nature, 588, 2020
3J2Y	Electron Cryo-microscopy of Chikungunya VLP in complex with neutralizing antibody Fab 9.8B Descriptor: 9.8B heavy chain, 9.8B light chain Authors: Sun, S, Xiang, Y, Rossmann, M.G. Deposit date: 2013-01-28 Release date: 2013-04-24 Last modified: 2018-07-18 Method: ELECTRON MICROSCOPY (14.9 Å) Cite: Structural analyses at pseudo atomic resolution of Chikungunya virus and antibodies show mechanisms of neutralization. Elife, 2, 2013
7K8S	Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C002 (state 1) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C002 Fab Heavy Chain, ... Authors: Barnes, C.O, Malyutin, A.G, Bjorkman, P.J. Deposit date: 2020-09-27 Release date: 2020-10-21 Last modified: 2021-01-13 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies. Nature, 588, 2020
8SW7	BG505 Boost2 SOSIP.664 in complex with NHP polyclonal antibody FP1 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 Boost 2 gp120, BG505 Boost 2 gp41, ... Authors: Pratap, P.P, Antansijevic, A, Ozorowski, G, Ward, A.B. Deposit date: 2023-05-17 Release date: 2023-07-26 Method: ELECTRON MICROSCOPY (3.37 Å) Cite: Focusing antibody responses to the fusion peptide in rhesus macaques. Biorxiv, 2023
7K8Z	Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C135 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C135 Fab Heavy Chain, ... Authors: Barnes, C.O, Bjorkman, P.J. Deposit date: 2020-09-27 Release date: 2020-10-21 Last modified: 2021-01-13 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies. Nature, 588, 2020
7K8V	Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C110 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C110 Fab Heavy Chain, ... Authors: Dam, K.A, Barnes, C.O, Bjorkman, P.J. Deposit date: 2020-09-27 Release date: 2020-10-21 Last modified: 2021-01-13 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies. Nature, 588, 2020
7K8W	Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C119 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C119 Fab Heavy Chain, ... Authors: Sharaf, N.G, Barnes, C.O, Bjorkman, P.J. Deposit date: 2020-09-27 Release date: 2020-10-21 Last modified: 2021-01-13 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies. Nature, 588, 2020
6UUH	Crystal structure of broad and potent HIV-1 neutralizing antibody 438-B11 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, B11 Fab Heavy Chain, B11 Fab Light Chain, ... Authors: Kumar, S, Wilson, I.A. Deposit date: 2019-10-30 Release date: 2020-09-23 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.7 Å) Cite: A V H 1-69 antibody lineage from an infected Chinese donor potently neutralizes HIV-1 by targeting the V3 glycan supersite. Sci Adv, 6, 2020
6MLK	Structure of Thioesterase from DEBS with a thioesterase-specific antibody Descriptor: 6-deoxyerythronolide-B synthase EryA3, modules 5 and 6, CHLORIDE ION, ... Authors: Mathews, I.I, Li, X, Khosla, C. Deposit date: 2018-09-27 Release date: 2018-10-17 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Discovery and Characterization of a Thioesterase-Specific Monoclonal Antibody That Recognizes the 6-Deoxyerythronolide B Synthase. Biochemistry, 57, 2018
7K8U	Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, C104 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C104 Fab Heavy Chain, ... Authors: Barnes, C.O, Malyutin, A.G, Bjorkman, P.J. Deposit date: 2020-09-27 Release date: 2020-10-21 Last modified: 2021-01-13 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies. Nature, 588, 2020
7K90	Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, C144 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, C144 Fab Heavy Chain, C144 Fab Light Chain, ... Authors: Barnes, C.O, Esswein, S.R, Bjorkman, P.J. Deposit date: 2020-09-27 Release date: 2020-10-21 Last modified: 2021-01-13 Method: ELECTRON MICROSCOPY (3.24 Å) Cite: SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies. Nature, 588, 2020
1DQL	CRYSTAL STRUCTURE OF AN UNLIGANDED (NATIVE) FV FROM A HUMAN IGM ANTI-PEPTIDE ANTIBODY Descriptor: IGM MEZ IMMUNOGLOBULIN Authors: Ramsland, P.A, Shan, L, Moomaw, C.R, Slaughter, C.A, Guddat, L.W, Edmundson, A.B. Deposit date: 2000-01-04 Release date: 2000-10-04 Last modified: 2019-12-25 Method: X-RAY DIFFRACTION (2.6 Å) Cite: An unusual human IgM antibody with a protruding HCDR3 and high avidity for its peptide ligands. Mol.Immunol., 37, 2000
6LZ9	t8E4 antibody Fab complexed with the active form of HGF Descriptor: Heavy chain of t8E4 Fab fragment, Hepatocyte growth factor, Light chain of t8E4 Fab fragment Authors: Kitago, Y, Umitsu, M, Takagi, J. Deposit date: 2020-02-18 Release date: 2020-03-11 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.8 Å) Cite: t8E4 antibody Fab complexed with the active form of HGF To Be Published
8TOA	CryoEM structure of H7 hemagglutinin from A/Shanghai2/2013 H7N9 in complex with a human neutralizing antibody H7.HK2 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, H7.HK2 Neutralizing Antibody Heavy Chain, H7.HK2 Neutralizing Antibody Light Chain, ... Authors: Morano, N.C, Becker, J.E, Wu, X, Shapiro, L. Deposit date: 2023-08-03 Release date: 2024-05-15 Method: ELECTRON MICROSCOPY (3.69 Å) Cite: CryoEM structure of H7 hemagglutinin from A/Shanghai2/2013 H7N9 in complex with a human neutralizing antibody H7.HK1 To Be Published
5U4L	RTA-V1C7_G29R-high-salt Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, PHOSPHATE ION, ... Authors: Rudolph, M.J, Mantis, N. Deposit date: 2016-12-05 Release date: 2017-12-13 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Using homology modeling to interrogate binding affinity in neutralization of ricin toxin by a family of single domain antibodies. Proteins, 85, 2017
6DG2	Antigen Binding Fragment of the Pan-ebolavirus Monoclonal Antibody 6D6 Descriptor: 6D6 Fab heavy chain, 6D6 Fab light chain Authors: Milligan, J.C, Saphire, E.O. Deposit date: 2018-05-16 Release date: 2018-09-26 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.96 Å) Cite: Structural Characterization of Pan-Ebolavirus Antibody 6D6 Targeting the Fusion Peptide of the Surface Glycoprotein. J. Infect. Dis., 219, 2019
5EOQ	Structure of the murine Fab 1G6 bound to the vaccinia virus A27 peptide 31-40 Descriptor: Anti vaccinia virus A27 antibody Fab 1G6 heavy chain, Anti vaccinia virus A27 antibody Fab 1G6 light chain, Protein A27 Authors: Matho, M.H, Zajonc, D.M. Deposit date: 2015-11-10 Release date: 2016-03-02 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Linear Epitopes in Vaccinia Virus A27 Are Targets of Protective Antibodies Induced by Vaccination against Smallpox. J.Virol., 90, 2016
6ULE	Crystal structure of 2541 Fab in complex with circumsporozoite protein NANP5 Descriptor: 2541 Antibody, heavy chain, light chain, ... Authors: Thai, E, Scally, S.W, Murugan, R, Wardemann, H, Julien, J.P. Deposit date: 2019-10-07 Release date: 2020-06-10 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs. Nat. Med., 26, 2020
4K8R	An Antibody Against the C-terminal Domain of PCSK9 lowers LDL Cholesterol Levels in vivo Descriptor: Fab1, heavy chain, light chain, ... Authors: Schiele, F, Nar, H. Deposit date: 2013-04-18 Release date: 2013-05-08 Last modified: 2019-08-21 Method: X-RAY DIFFRACTION (3.22 Å) Cite: An Antibody against the C-Terminal Domain of PCSK9 Lowers LDL Cholesterol Levels In Vivo. J.Mol.Biol., 426, 2014
5XRQ	Crystal structure of human monoclonal antibody H3v-47 Descriptor: Fab H3v-47 heavy chain, Fab H3v-47 light chain Authors: Zhang, H, Willson, I.A. Deposit date: 2017-06-09 Release date: 2018-07-25 Last modified: 2019-12-18 Method: X-RAY DIFFRACTION (2.6 Å) Cite: A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA. Nat Commun, 9, 2018
6UM6	Cryo-EM structure of HIV-1 neutralizing antibody DH270.6 in complex with CH848 10.17DT Env Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Acharya, P, Henderson, R.C, Saunder, K.O, Haynes, B.F. Deposit date: 2019-10-09 Release date: 2019-12-18 Last modified: 2020-07-29 Method: ELECTRON MICROSCOPY (4.3 Å) Cite: Targeted selection of HIV-specific antibody mutations by engineering B cell maturation. Science, 366, 2019
6V4Q	Crystal structure of a MR78-like antibody naive-1 Fab Descriptor: GLYCEROL, ISOPROPYL ALCOHOL, Naive-1 Fab heavy chain, ... Authors: Bozhanova, N.G, Crowe, J.E, Meiler, J. Deposit date: 2019-11-28 Release date: 2020-11-25 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.39 Å) Cite: Discovery of Marburg virus neutralizing antibodies from virus-naive human antibody repertoires using large-scale structural predictions. Proc.Natl.Acad.Sci.USA, 117, 2020

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