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4AVQ
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BU of 4avq by Molmil
Influenza strain pH1N1 2009 polymerase subunit PA endonuclease
Descriptor: MAGNESIUM ION, MANGANESE (II) ION, POLYMERASE PA
Authors:Kowalinski, E, Zubieta, C, Wolkerstorfer, A, Szolar, O.H, Ruigrok, R.W, Cusack, S.
Deposit date:2012-05-29
Release date:2012-08-22
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza Ph1N1 (2009) Polymerase.
Plos Pathog., 8, 2012
1GUZ
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BU of 1guz by Molmil
Structural Basis for Thermophilic Protein Stability: Structures of Thermophilic and Mesophilic Malate Dehydrogenases
Descriptor: MALATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Dalhus, B, Sarinen, M, Sauer, U.H, Eklund, P, Johansson, K, Karlsson, A, Ramaswamy, S, Bjork, A, Synstad, B, Naterstad, K, Sirevag, R, Eklund, H.
Deposit date:2002-02-04
Release date:2002-02-21
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for Thermophilic Protein Stability: Structures of Thermophilic and Mesophilic Malate Dehydrogenases
J.Mol.Biol., 318, 2002
4IH7
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BU of 4ih7 by Molmil
Hepatitis C Virus polymerase NS5B (BK) with fragment-based compounds
Descriptor: 3-(3-tert-butylphenyl)pyridin-2(1H)-one, RNA-directed RNA polymerase, ZINC ION
Authors:Harris, S.F, Wong, A.
Deposit date:2012-12-18
Release date:2013-07-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:De novo fragment design: a medicinal chemistry approach to fragment-based lead generation.
J.Med.Chem., 56, 2013
4AWG
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BU of 4awg by Molmil
Influenza strain pH1N1 2009 polymerase subunit PA endonuclease in complex with diketo compound 3
Descriptor: (2Z)-4-[(3S)-1-benzyl-3-(4-chlorobenzyl)piperidin-3-yl]-2-hydroxy-4-oxobut-2-enoic acid, MANGANESE (II) ION, POLYMERASE PA, ...
Authors:Kowalinski, E, Zubieta, C, Wolkerstorfer, A, Szolar, O.H, Ruigrok, R.W, Cusack, S.
Deposit date:2012-06-03
Release date:2012-08-22
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza Ph1N1 (2009) Polymerase.
Plos Pathog., 8, 2012
8FG2
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BU of 8fg2 by Molmil
SARS-CoV-2 Nucleocapsid dimer structure determined from COVID-19 patients
Descriptor: Nucleoprotein
Authors:Casasanta, M, Jonaid, G.M, Kaylor, L, Luqiu, W, DiCecco, L, Solares, M, Berry, S, Kelly, D.F.
Deposit date:2022-12-12
Release date:2023-01-11
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Structural Insights of the SARS-CoV-2 Nucleocapsid Protein: Implications for the Inner-workings of Rapid Antigen Tests.
Microsc Microanal, 29, 2023
8FD5
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BU of 8fd5 by Molmil
Nucleocapsid monomer structure from SARS-CoV-2
Descriptor: Nucleoprotein
Authors:Casasanta, M, Jonaid, G.M, Kaylor, L, Luqiu, W, DiCecco, L, Solares, M, Berry, S, Kelly, D.F.
Deposit date:2022-12-02
Release date:2023-01-11
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (4.57 Å)
Cite:Structural Insights of the SARS-CoV-2 Nucleocapsid Protein: Implications for the Inner-workings of Rapid Antigen Tests.
Microsc Microanal, 29, 2023
4MBB
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BU of 4mbb by Molmil
Cubic crystal form of PIR1 dual specificity phosphatase core
Descriptor: CHLORIDE ION, PHOSPHATE ION, RNA/RNP complex-1-interacting phosphatase
Authors:Sankhala, R.S, Lokareddy, R.K, Cingolani, G.
Deposit date:2013-08-19
Release date:2013-12-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.849 Å)
Cite:Structure of Human PIR1, an Atypical Dual-Specificity Phosphatase.
Biochemistry, 53, 2014
4BXT
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BU of 4bxt by Molmil
Crystal structure of the human metapneumovirus phosphoprotein tetramerization domain
Descriptor: PHOSPHOPROTEIN P
Authors:Leyrat, C, Renner, M, Harlos, K, Grimes, J.M.
Deposit date:2013-07-15
Release date:2013-11-20
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (3.13 Å)
Cite:Solution and Crystallographic Structures of the Central Region of the Phosphoprotein from Human Metapneumovirus
Plos One, 8, 2013
3S4P
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BU of 3s4p by Molmil
Crystal structure of the bacterial ribosomal decoding site complexed with an amphiphilic paromomycin O2''-ether analogue
Descriptor: (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-2-O-{2-[(2-phenylethyl)amino]ethyl}-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside, RNA (5'-R(P*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3')
Authors:Szychowski, J, Kondo, J, Zahr, O, Auclair, K, Westhof, E, Hanessian, S, Keillor, J.W.
Deposit date:2011-05-20
Release date:2011-09-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Inhibition of aminoglycoside-deactivating enzymes APH(3')-IIIa and AAC(6')-Ii by amphiphilic paromomycin O2''-ether analogues
Chemmedchem, 6, 2011
3AJV
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BU of 3ajv by Molmil
Splicing endonuclease from Aeropyrum pernix
Descriptor: CHLORIDE ION, GLYCEROL, Putative uncharacterized protein, ...
Authors:Yoshinari, S, Watanabe, Y, Okuda, M, Shiba, T, Inaoka, K.D, Kurisu, G.
Deposit date:2010-06-19
Release date:2010-11-17
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A Conserved Lysine Residue in the Crenarchaea-Specific Loop is Important for the Crenarchaeal Splicing Endonuclease Activity.
J.Mol.Biol., 405, 2011
2AS0
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BU of 2as0 by Molmil
Crystal Structure of PH1915 (APC 5817): A Hypothetical RNA Methyltransferase
Descriptor: hypothetical protein PH1915
Authors:Sun, W, Xu, X, Pavlova, M, Edwards, A.M, Joachimiak, A, Savchenko, A, Christendat, D, Midwest Center for Structural Genomics (MCSG)
Deposit date:2005-08-22
Release date:2005-09-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structure of a novel SAM-dependent methyltransferase PH1915 from Pyrococcus horikoshii.
Protein Sci., 14, 2005
3QAZ
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BU of 3qaz by Molmil
IL-2 mutant D10 ternary complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor common subunit gamma, Interleukin-2, ...
Authors:Levin, A.M, Bates, D.L, Ring, A.M, Lin, J.T, Su, L, Krieg, C, Bowman, G.R, Novick, P, Pande, V.S, Khort, H.E, Boyman, O, Gathman, C.G, Garcia, K.C.
Deposit date:2011-01-12
Release date:2012-04-11
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.802 Å)
Cite:Exploiting a natural conformational switch to engineer an interleukin-2 'superkine'
Nature, 484, 2012
11BG
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BU of 11bg by Molmil
A POTENTIAL ALLOSTERIC SUBSITE GENERATED BY DOMAIN SWAPPING IN BOVINE SEMINAL RIBONUCLEASE
Descriptor: PROTEIN (BOVINE SEMINAL RIBONUCLEASE), SULFATE ION, URIDYLYL-2'-5'-PHOSPHO-GUANOSINE
Authors:Vitagliano, L, Adinolfi, S, Sica, F, Merlino, A, Zagari, A, Mazzarella, L.
Deposit date:1999-03-11
Release date:1999-11-05
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A potential allosteric subsite generated by domain swapping in bovine seminal ribonuclease.
J.Mol.Biol., 293, 1999
6U79
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BU of 6u79 by Molmil
Solution NMR structure of 5' UTR stem loop B from West Nile Virus
Descriptor: 5' UTR region stem loop
Authors:Sharma, S, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2019-09-01
Release date:2020-08-26
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NMR structure of Dengue West Nile viruses stem-loop B: A key cis-acting element for flavivirus replication.
Biochem.Biophys.Res.Commun., 531, 2020
7YYO
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BU of 7yyo by Molmil
Cryo-EM structure of an a-carboxysome RuBisCO enzyme at 2.9 A resolution
Descriptor: 2-CARBOXYARABINITOL-1,5-DIPHOSPHATE, MAGNESIUM ION, Ribulose bisphosphate carboxylase large chain, ...
Authors:Mann, D, Evans, S.L, Bergeron, J.R.C.
Deposit date:2022-02-18
Release date:2023-01-25
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (2.87 Å)
Cite:Single-particle cryo-EM analysis of the shell architecture and internal organization of an intact alpha-carboxysome.
Structure, 31, 2023
7Z3R
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BU of 7z3r by Molmil
Crystal structure of the mouse leptin:LepR-IgCRH2 complex to 2.95 A resolution.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Leptin, Leptin receptor
Authors:Verstraete, K, Verschueren, K, Savvides, S.N, Tsirigotaki, A.
Deposit date:2022-03-02
Release date:2023-03-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.951 Å)
Cite:Mechanism of receptor assembly via the pleiotropic adipokine Leptin.
Nat.Struct.Mol.Biol., 30, 2023
7ZAK
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BU of 7zak by Molmil
Crystal structure of HLA-DP (DPA1*02:01-DPB1*01:01) in complex with a peptide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, MAGNESIUM ION, ...
Authors:Racle, J, Guillaume, P, Larabi, A, Lau, K, Pojer, F, Gfeller, D.
Deposit date:2022-03-22
Release date:2023-03-29
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Machine learning predictions of MHC-II specificities reveal alternative binding mode of class II epitopes.
Immunity, 56, 2023
7ZFR
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BU of 7zfr by Molmil
Crystal structure of HLA-DP (DPA1*02:01-DPB1*01:01) in complex with a peptide bound in the reverse direction
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MHC class II HLA-DP alpha chain (DPA1*02:01), MHC class II HLA-DP beta chain (DPB1*01:01), ...
Authors:Racle, J, Guillaume, P, Larabi, A, Lau, K, Pojer, F, Gfeller, D.
Deposit date:2022-04-01
Release date:2023-04-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Machine learning predictions of MHC-II specificities reveal alternative binding mode of class II epitopes.
Immunity, 56, 2023
4EO6
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BU of 4eo6 by Molmil
HCV NS5B polymerase inhibitors: Tri-substituted acylhydrazines as tertiary amide bioisosteres
Descriptor: 5-(3,3-dimethylbut-1-yn-1-yl)-3-{[(trans-4-methylcyclohexyl)carbonyl](propan-2-yl)amino}thiophene-2-carboxylic acid, RNA-directed RNA polymerase
Authors:Appleby, T.C, Canales, E, Watkins, W.J.
Deposit date:2012-04-13
Release date:2012-06-27
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.791 Å)
Cite:Tri-substituted acylhydrazines as tertiary amide bioisosteres: HCV NS5B polymerase inhibitors.
Bioorg.Med.Chem.Lett., 22, 2012
5FKF
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BU of 5fkf by Molmil
SAM-I riboswitch bearing the H. marismortui Kt-7 variant 3bn is UC
Descriptor: BARIUM ION, POTASSIUM ION, S-ADENOSYLMETHIONINE, ...
Authors:Huang, L, Lilley, D.M.J.
Deposit date:2015-10-15
Release date:2016-05-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A Critical Base Pair in K-Turns Determines the Conformational Class Adopted, and Correlates with Biological Function.
Nucleic Acids Res., 44, 2016
1OUP
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BU of 1oup by Molmil
Crystal structure of the periplasmic endonuclease Vvn complexed with octamer double stranded DNA
Descriptor: 5'-D(*GP*CP*GP*AP*TP*C)-3', 5'-D(*GP*CP*GP*AP*TP*CP*GP*C)-3', 5'-D(P*GP*C)-3', ...
Authors:Yuan, H.S, Li, C.-L.
Deposit date:2003-03-25
Release date:2003-08-05
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:DNA binding and cleavage by the periplasmic nuclease Vvn: a novel structure with a known active site.
Embo J., 22, 2003
7Q97
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BU of 7q97 by Molmil
Structure of the bacterial type VI secretion system effector RhsA.
Descriptor: Rhs family protein
Authors:Guenther, P, Quentin, D, Ahmad, S, Sachar, K, Gatsogiannis, C, Whitney, J.C, Raunser, S.
Deposit date:2021-11-12
Release date:2021-12-22
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure of a bacterial Rhs effector exported by the type VI secretion system.
Plos Pathog., 18, 2022
5FK1
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BU of 5fk1 by Molmil
SAM-I riboswitch bearing the H. marismortui Kt-7 variant 3bn is UG
Descriptor: BARIUM ION, S-ADENOSYLMETHIONINE, SAM-I RIBOSWITCH, ...
Authors:Huang, L, Lilley, D.M.J.
Deposit date:2015-10-14
Release date:2016-05-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A Critical Base Pair in K-Turns Determines the Conformational Class Adopted, and Correlates with Biological Function.
Nucleic Acids Res., 44, 2016
5FKH
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BU of 5fkh by Molmil
SAM-I riboswitch bearing the H. marismortui Kt-7 variant 3bn is CU
Descriptor: BARIUM ION, POTASSIUM ION, S-ADENOSYLMETHIONINE, ...
Authors:Huang, L, Lilley, D.M.J.
Deposit date:2015-10-15
Release date:2016-05-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:A Critical Base Pair in K-Turns Determines the Conformational Class Adopted, and Correlates with Biological Function.
Nucleic Acids Res., 44, 2016
5FKE
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BU of 5fke by Molmil
SAM-I riboswitch bearing the H. marismortui Kt-7 variant 3bn is GU
Descriptor: BARIUM ION, POTASSIUM ION, S-ADENOSYLMETHIONINE, ...
Authors:Huang, L, Lilley, D.M.J.
Deposit date:2015-10-15
Release date:2016-05-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A Critical Base Pair in K-Turns Determines the Conformational Class Adopted, and Correlates with Biological Function.
Nucleic Acids Res., 44, 2016

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数据于2024-07-17公开中

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