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2JCN
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The crystal structure of BAK1 - a mitochondrial apoptosis regulator
Descriptor: BCL-2 HOMOLOGOUS ANTAGONIST/KILLER, SULFATE ION
Authors:Moche, M, Stenmark, P, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Edwards, A, Ericsson, U.B, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg Schiavone, L, Johansson, I, Karlberg, T, Kosinska, U, Kotenyova, T, Lundgren, S, Nilsson, M.E, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Sundstrom, M, Uppenberg, J, Upsten, M, Thorsell, A.G, van den Berg, S, Weigelt, J, Nordlund, P, Structural Genomics Consortium (SGC)
Deposit date:2006-12-27
Release date:2007-01-04
Last modified:2018-06-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Crystal Structure of Bak1 - an Apoptosis Trigger in the Mitochondrial Outer Membrane
To be Published
2JQ9
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VPS4A MIT-CHMP1A complex
Descriptor: Chromatin-modifying protein 1a, Vacuolar protein sorting-associating protein 4A
Authors:Stuchell-Brereton, M.D, Skalicky, J.J, Kieffer, C, Ghaffarian, S, Sundquist, W.I.
Deposit date:2007-05-30
Release date:2007-10-16
Last modified:2023-12-20
Method:SOLUTION NMR
Cite:ESCRT-III recognition by VPS4 ATPases.
Nature, 449, 2007
2JV0
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SET domain of RIZ1 tumor suppressor (PRDM2)
Descriptor: PR domain zinc finger protein 2
Authors:Briknarova, K.
Deposit date:2007-09-10
Release date:2008-01-22
Last modified:2021-10-20
Method:SOLUTION NMR
Cite:Structural studies of the SET domain from RIZ1 tumor suppressor
Biochem.Biophys.Res.Commun., 366, 2008
2JZX
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BU of 2jzx by Molmil
PCBP2 KH1-KH2 domains
Descriptor: Poly(rC)-binding protein 2
Authors:Du, Z, Fenn, S, Tjhen, R, James, T.
Deposit date:2008-01-21
Release date:2008-08-12
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structure of the first and second KH domains of human poly-C binding protein-2 reveals insights into its regulatory mechanisms
To be Published
2K0R
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BU of 2k0r by Molmil
Solution structure of the C103S mutant of the N-terminal Domain of DsbD from Neisseria meningitidis
Descriptor: Thiol:disulfide interchange protein dsbD
Authors:Quinternet, M, Selme, L, Tsan, P, Beaufils, C, Jacob, C, Boschi-Muller, S, Averlant-Petit, M, Branlant, G, Cung, M.
Deposit date:2008-02-13
Release date:2008-11-11
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure and backbone dynamics of the cysteine 103 to serine mutant of the N-terminal domain of DsbD from Neisseria meningitidis.
Biochemistry, 47, 2008
2JYH
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Rigid-body refinement of the tetraloop-receptor RNA complex
Descriptor: RNA (43-MER)
Authors:Zuo, X, Wang, J, Foster, T.R, Schwieters, C.D, Tiede, D.M.
Deposit date:2007-12-13
Release date:2008-10-07
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Rigid-body refinement of the tetraloop-receptor RNA complex
To be Published
2K2S
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BU of 2k2s by Molmil
structure of the MIC1-GLD/MIC6-EGF complex from Toxoplasma gondii
Descriptor: Micronemal protein 1, Micronemal protein 6
Authors:Matthews, S.
Deposit date:2008-04-11
Release date:2009-02-24
Last modified:2011-07-27
Method:SOLUTION NMR
Cite:Structural insights into microneme protein assembly reveal a new mode of EGF domain recognition
Embo Rep., 9, 2008
2K4H
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BU of 2k4h by Molmil
Solution structure of the HIV-2 myristoylated Matrix protein
Descriptor: HIV-2 myristoylated matrix protein, MYRISTIC ACID
Authors:Saad, J.S, Ablan, S.D, Ghanam, R.H, Kim, A, Andrews, K, Nagashima, K, Freed, E.O, Summers, M.F.
Deposit date:2008-06-08
Release date:2008-08-12
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Structure of the myristylated human immunodeficiency virus type 2 matrix protein and the role of phosphatidylinositol-(4,5)-bisphosphate in membrane targeting.
J.Mol.Biol., 382, 2008
2JMV
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Solution structure of scytovirin refined against residual dipolar couplings
Descriptor: Scytovirin
Authors:McFeeters, R.L, Byrd, R.A.
Deposit date:2006-12-07
Release date:2007-06-12
Last modified:2023-12-20
Method:SOLUTION NMR
Cite:The novel fold of scytovirin reveals a new twist for antiviral entry inhibitors
J.Mol.Biol., 369, 2007
2JCP
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BU of 2jcp by Molmil
The hyaluronan binding domain of murine CD44
Descriptor: CD44 ANTIGEN
Authors:Banerji, S, Wright, A.J, Noble, M.E.M, Mahoney, D.J, Campbell, I.D, Day, A.J, Jackson, D.G.
Deposit date:2007-01-03
Release date:2007-01-30
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structures of the Cd44-Hyaluronan Complex Provide Insight Into a Fundamental Carbohydrate-Protein Interaction.
Nat.Struct.Mol.Biol., 14, 2008
2JZY
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Solution structure of C-terminal effector domain of putative two-component-system response regulator involved in copper resistance from Klebsiella pneumoniae
Descriptor: Transcriptional regulatory protein PcoR
Authors:Hung, K, Fang, P, Chang, C, Tsai, S, Huang, T.
Deposit date:2008-01-22
Release date:2009-01-27
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structure of C-terminal effector domain of putative two-component-system response regulator involved in copper resistance from Klebsiella pneumoniae
To be Published
2JEW
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Crystal structure of ((2S)-5-amino-2-((1-n-propyl-1H-imidazol-4-yl) methyl)pentanoic acid) UK396,082 a TAFIa inhibitor, Bound to Activated Porcine Pancreatic carboxypeptidaseB
Descriptor: (2S)-5-AMINO-2-[(1-PROPYL-1H-IMIDAZOL-4-YL)METHYL]PENTANOIC ACID, CARBOXYPEPTIDASE B, ZINC ION
Authors:Brown, D.G, Moore, R.S.
Deposit date:2007-01-24
Release date:2007-11-20
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Discovery of potent & selective inhibitors of activated thrombin-activatable fibrinolysis inhibitor for the treatment of thrombosis.
J. Med. Chem., 50, 2007
2F2Q
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BU of 2f2q by Molmil
High resolution crystal structure of T4 lysozyme mutant L20R63/A liganded to guanidinium ion
Descriptor: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, GUANIDINE, ...
Authors:Yousef, M.S, Bischoff, N, Dyer, C.M, Baase, W.A, Matthews, B.W.
Deposit date:2005-11-17
Release date:2006-04-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Guanidinium derivatives bind preferentially and trigger long-distance conformational changes in an engineered T4 lysozyme.
Protein Sci., 15, 2006
2F32
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BU of 2f32 by Molmil
Xray crystal structure of lysozyme mutant L20/R63A liganded to ethylguanidinium
Descriptor: BETA-MERCAPTOETHANOL, Lysozyme, N-ETHYLGUANIDINE
Authors:Yousef, M.S, Bischoff, N, Dyer, C.M, Baase, W.A, Matthews, B.W.
Deposit date:2005-11-18
Release date:2006-04-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Guanidinium derivatives bind preferentially and trigger long-distance conformational changes in an engineered T4 lysozyme.
Protein Sci., 15, 2006
2F6J
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Crystal structure of PHD finger-linker-bromodomain fragment of human BPTF in the H3(1-15)K4me3 bound state
Descriptor: ZINC ION, bromodomain PHD finger transcription factor, histone H3, ...
Authors:Li, H, Patel, D.J.
Deposit date:2005-11-29
Release date:2006-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF.
Nature, 442, 2006
2FKG
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BU of 2fkg by Molmil
The Crystal Structure of Engineered OspA
Descriptor: Outer Surface Protein A
Authors:Makabe, K, Terechko, V, Gawlak, G, Yan, S, Koide, S.
Deposit date:2006-01-04
Release date:2006-11-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Atomic structures of peptide self-assembly mimics.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2F05
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BU of 2f05 by Molmil
Solution structure of free PAH2 domain of mSin3B
Descriptor: Paired amphipathic helix protein Sin3b
Authors:van Ingen, H, Baltussen, M.A, Aelen, J, Vuister, G.W.
Deposit date:2005-11-11
Release date:2006-03-28
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Role of Structural and Dynamical Plasticity in Sin3: The Free PAH2 Domain is a Folded Module in mSin3B
J.Mol.Biol., 358, 2006
2F9S
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BU of 2f9s by Molmil
2nd Crystal Structure Of A Soluble Domain Of ResA In The Oxidised Form
Descriptor: Thiol-disulfide oxidoreductase resA
Authors:Colbert, C.L, Wu, Q, Erbel, P.J.A, Gardner, K.H, Deisenhofer, J.
Deposit date:2005-12-06
Release date:2006-04-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.401 Å)
Cite:Mechanism of substrate specificity in Bacillus subtilis ResA, a thioredoxin-like protein involved in cytochrome c maturation
Proc.Natl.Acad.Sci.USA, 103, 2006
2JK4
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Structure of the human voltage-dependent anion channel
Descriptor: VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL PROTEIN 1
Authors:Bayrhuber, M, Meins, T, Habeck, M, Becker, S, Giller, K, Villinger, S, Vonrhein, C, Griesinger, C, Zweckstetter, M, Zeth, K.
Deposit date:2008-08-15
Release date:2008-10-14
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Structure of the Human Voltage-Dependent Anion Channel.
Proc.Natl.Acad.Sci.USA, 105, 2008
2JWP
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BU of 2jwp by Molmil
Malectin
Descriptor: Malectin
Authors:Schallus, T, Muhle-goll, C.
Deposit date:2007-10-23
Release date:2008-08-12
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Malectin: A Novel Carbohydrate-binding Protein of the Endoplasmic Reticulum and a Candidate Player in the Early Steps of Protein N-Glycosylation
Mol.Cell.Biol., 19, 2008
2JU5
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BU of 2ju5 by Molmil
DsbH Oxidoreductase
Descriptor: Thioredoxin Disulfide Isomerase
Authors:Ulmer, T.S.
Deposit date:2007-08-15
Release date:2007-11-27
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Insight into Disulfide Bond Catalysis in Chlamydia from the Structure and Function of DsbH, a Novel Oxidoreductase.
J.Biol.Chem., 283, 2008
2JZS
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BU of 2jzs by Molmil
Solution structure of the reduced form of the N-terminal domain of PilB from N. meningitidis.
Descriptor: Peptide methionine sulfoxide reductase msrA/msrB
Authors:Quinternet, M, Tsan, P, Neiers, F, Beaufils, C, Boschi-Muller, S, Averlant-Petit, M, Branlant, G, Cung, M.
Deposit date:2008-01-15
Release date:2008-07-29
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure and dynamics of the reduced and oxidized forms of the N-terminal domain of PilB from Neisseria meningitidis.
Biochemistry, 47, 2008
2K0E
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A Coupled Equilibrium Shift Mechanism in Calmodulin-Mediated Signal Transduction
Descriptor: CALCIUM ION, Calmodulin
Authors:Gsponer, J, Christodoulou, J, Cavalli, A, Bui, J.M, Richter, B, Dobson, C.M, Vendruscolo, M.
Deposit date:2008-02-02
Release date:2008-06-10
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:A coupled equilibrium shift mechanism in calmodulin-mediated signal transduction
Structure, 16, 2008
2K1A
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BU of 2k1a by Molmil
Bicelle-embedded integrin alpha(IIB) transmembrane segment
Descriptor: Integrin alpha-IIb
Authors:Lau, T.-L, Dua, V, Ulmer, T.S.
Deposit date:2008-02-25
Release date:2008-04-15
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure of the Integrin {alpha}IIb Transmembrane Segment.
J.Biol.Chem., 283, 2008
2K3H
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Structural determinants for Ca2+ and PIP2 binding by the C2A domain of rabphilin-3A
Descriptor: CALCIUM ION, Rabphilin-3A
Authors:Coudevylle, N, Montaville, P, Leonov, A, Zweckstetter, M, Becker, S.
Deposit date:2008-05-08
Release date:2008-10-21
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structural Determinants for Ca2+ and Phosphatidylinositol 4,5-Bisphosphate Binding by the C2A Domain of Rabphilin-3A.
J.Biol.Chem., 283, 2008

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