PDB: 7742 resultsInfo pagesStatus searchChemie searchBIRD

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1M9U	Crystal Structure of Earthworm Fibrinolytic Enzyme Component A from Eisenia fetida Descriptor: Earthworm Fibrinolytic Enzyme Authors: Chang, W, Liang, D, Tang, Y. Deposit date: 2002-07-29 Release date: 2002-08-14 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal structure of earthworm fibrinolytic enzyme component a: revealing the structural determinants of its dual fibrinolytic activity. J.Mol.Biol., 321, 2002
1QNJ	THE STRUCTURE OF NATIVE PORCINE PANCREATIC ELASTASE AT ATOMIC RESOLUTION (1.1 A) Descriptor: ELASTASE, SODIUM ION, SULFATE ION Authors: Wurtele, M, Hahn, M, Hilpert, K, Hohne, W. Deposit date: 1999-10-15 Release date: 2000-03-31 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.1 Å) Cite: Atomic Resolution Structure of Native Porcine Pancreatic Elastase at 1.1 A Acta Crystallogr.,Sect.D, 56, 2000
229L	GENERATING LIGAND BINDING SITES IN T4 LYSOZYME USING DEFICIENCY-CREATING SUBSTITUTIONS Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, GUANIDINE, ... Authors: Baldwin, E.P, Baase, W.A, Zhang, X.-J, Feher, V, Matthews, B.W. Deposit date: 1997-06-26 Release date: 1998-03-18 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Generation of ligand binding sites in T4 lysozyme by deficiency-creating substitutions. J.Mol.Biol., 277, 1998
227L	GENERATING LIGAND BINDING SITES IN T4 LYSOZYME USING DEFICIENCY-CREATING SUBSTITUTIONS Descriptor: BENZENE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... Authors: Baldwin, E.P, Baase, W.A, Zhang, X.-J, Feher, V, Matthews, B.W. Deposit date: 1997-06-25 Release date: 1998-03-18 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2 Å) Cite: Generation of ligand binding sites in T4 lysozyme by deficiency-creating substitutions. J.Mol.Biol., 277, 1998
2AOT	Histamine Methyltransferase Complexed with the Antihistamine Drug Diphenhydramine Descriptor: Histamine N-methyltransferase, N-[2-(BENZHYDRYLOXY)ETHYL]-N,N-DIMETHYLAMINE, S-ADENOSYL-L-HOMOCYSTEINE Authors: Horton, J.R, Sawada, K, Nishibori, M, Cheng, X. Deposit date: 2005-08-14 Release date: 2005-09-13 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural basis for inhibition of histamine N-methyltransferase by diverse drugs J.Mol.Biol., 353, 2005
2AOW	Histamine Methyltransferase (Natural Variant I105) Complexed with the Acetylcholinesterase Inhibitor and Altzheimer's Disease Drug Tacrine Descriptor: Histamine N-methyltransferase, TACRINE Authors: Horton, J.R, Sawada, K, Nishibori, M, Cheng, X. Deposit date: 2005-08-14 Release date: 2005-09-13 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.97 Å) Cite: Structural basis for inhibition of histamine N-methyltransferase by diverse drugs J.Mol.Biol., 353, 2005
6LPR	STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS Descriptor: ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-NORLEUCINE BORONIC ACID INHIBITOR, SULFATE ION Authors: Bone, R, Agard, D.A. Deposit date: 1991-08-05 Release date: 1993-01-15 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural basis for broad specificity in alpha-lytic protease mutants. Biochemistry, 30, 1991
4PRO	ALPHA-LYTIC PROTEASE COMPLEXED WITH PRO REGION Descriptor: ALPHA-LYTIC PROTEASE Authors: Sauter, N.K, Mau, T, Rader, S.D, Agard, D.A. Deposit date: 1998-10-01 Release date: 1999-05-18 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structure of alpha-lytic protease complexed with its pro region. Nat.Struct.Biol., 5, 1998
7LPR	STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS Descriptor: ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-LEUCINE BORONIC ACID INHIBITOR, SULFATE ION Authors: Fujishige, A, Bone, R, Agard, D.A. Deposit date: 1991-08-05 Release date: 1993-01-15 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Structural basis for broad specificity in alpha-lytic protease mutants. Biochemistry, 30, 1991
6Q12	Structure of pro-Esp mutant- S66V Descriptor: Glutamyl endopeptidase Authors: Manne, K, Narayana, S.V.L. Deposit date: 2019-08-02 Release date: 2019-08-14 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural insights into the role of the N-terminus in the activation and function of extracellular serine protease from Staphylococcus epidermidis. Acta Crystallogr D Struct Biol, 76, 2020
6Q24	Structure of pro-Esp mutant- S235A Descriptor: Glutamyl endopeptidase Authors: Manne, K, Narayana, S.V.L. Deposit date: 2019-08-06 Release date: 2019-08-21 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Structural insights into the role of the N-terminus in the activation and function of extracellular serine protease from Staphylococcus epidermidis. Acta Crystallogr D Struct Biol, 76, 2020
2Z71	Structure of truncated mutant CYS1GLY of penicillin V acylase from bacillus sphaericus co-crystallized with penicillin V Descriptor: (2S,5R,6R)-3,3-DIMETHYL-7-OXO-6-(2-PHENOXYACETAMIDO)-4-THIA-1- AZABICYCLO(3.2.0)HEPTANE-2-CARBOXYLIC ACID, Penicillin acylase Authors: Pathak, M.C, Brannigan, J, Dodson, G.G, Suresh, C.G. Deposit date: 2007-08-10 Release date: 2008-08-26 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Studies on the catalysis and post translational processing of penicillin V acylase To be published
2EST	Crystallographic study of the binding of a trifluoroacetyl dipeptide anilide inhibitor with elastase Descriptor: 6-ammonio-N-(trifluoroacetyl)-L-norleucyl-N-[4-(trifluoromethyl)phenyl]-L-alaninamide, ELASTASE, SULFATE ION Authors: Sieker, L.C, Hughes, D.L. Deposit date: 1986-03-24 Release date: 1986-05-07 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystallographic study of the binding of a trifluoroacetyl dipeptide anilide inhibitor with elastase. J.Mol.Biol., 162, 1982
9API	THE S VARIANT OF HUMAN ALPHA1-ANTITRYPSIN, STRUCTURE AND IMPLICATIONS FOR FUNCTION AND METABOLISM Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA 1-ANTITRYPSIN, ... Authors: Loebermann, H, Tokuoka, R, Deisenhofer, J, Huber, R. Deposit date: 1988-09-08 Release date: 1990-10-15 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3 Å) Cite: The S variant of human alpha 1-antitrypsin, structure and implications for function and metabolism. Protein Eng., 2, 1989
3LQM	Structure of the IL-10R2 Common Chain Descriptor: GLYCEROL, Interleukin-10 receptor subunit beta, SULFATE ION Authors: Yoon, S.I, Walter, M.R. Deposit date: 2010-02-09 Release date: 2010-05-26 Last modified: 2021-10-13 Method: X-RAY DIFFRACTION (2.14 Å) Cite: Structure and mechanism of receptor sharing by the IL-10R2 common chain. Structure, 18, 2010
3V56	Re-refinement of PDB entry 1OSG - Complex between BAFF and a BR3 derived peptide presented in a beta-hairpin scaffold - reveals an additonal copy of the peptide. Descriptor: BR3 derived peptive, SULFATE ION, Tumor necrosis factor ligand superfamily member 13B Authors: Smart, O.S, Womack, T.O, Flensburg, C, Keller, P, Sharff, A, Paciorek, W, Vonrhein, C, Bricogne, G. Deposit date: 2011-12-16 Release date: 2012-03-28 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (3 Å) Cite: Exploiting structure similarity in refinement: automated NCS and target-structure restraints in BUSTER. Acta Crystallogr.,Sect.D, 68, 2012
8A7T	beta-2-microglobulin D76N amyloid fibril form 2PFa Descriptor: Beta-2-microglobulin Authors: Wilkinson, M, Gallardo, R, Radford, S.E, Ranson, N.A. Deposit date: 2022-06-21 Release date: 2023-03-22 Last modified: 2023-12-13 Method: ELECTRON MICROSCOPY (3 Å) Cite: Disease-relevant beta 2 -microglobulin variants share a common amyloid fold. Nat Commun, 14, 2023
8A7Q	beta-2-microglobulin V27M amyloid fibril form 4PF Descriptor: Beta-2-microglobulin Authors: Wilkinson, M, Gallardo, R, Radford, S.E, Ranson, N.A. Deposit date: 2022-06-21 Release date: 2023-03-22 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Disease-relevant beta 2 -microglobulin variants share a common amyloid fold. Nat Commun, 14, 2023
8OXV	Transglutaminase 3 zymogen in complex with DH patient-derived Fab DH63-B02 Descriptor: 1,2-ETHANEDIOL, Antibody Fab fragment Heavy chain, Antibody Fab fragment light chain, ... Authors: Heggelund, J.E, Sollid, L.M. Deposit date: 2023-05-02 Release date: 2023-10-18 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Autoantibody binding and unique enzyme-substrate intermediate conformation of human transglutaminase 3. Nat Commun, 14, 2023
1HAY	Snapshots of serine protease catalysis: (B) acyl-enzyme intermediate between porcine pancreatic elastase and human beta-casomorphin-7 jumped to pH 10 for 10 seconds Descriptor: CALCIUM ION, ELASTASE 1, SULFATE ION Authors: Wilmouth, R.C, Edman, K, Neutze, R, Wright, P.A, Clifton, I.J, Schneider, T.R, Schofield, C.J, Hajdu, J. Deposit date: 2001-04-10 Release date: 2001-08-02 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.7 Å) Cite: X-Ray Snapshots of Serine Protease Catalysis Reveal a Tetrahedral Intermediate Nat.Struct.Biol., 8, 2001
8LPR	STRUCTURAL BASIS FOR BROAD SPECIFICITY IN ALPHA-LYTIC PROTEASE MUTANTS Descriptor: ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-PHENYLALANINE BORONIC ACID INHIBITOR, SULFATE ION Authors: Fujishige, A, Bone, R, Agard, D.A. Deposit date: 1991-08-05 Release date: 1993-01-15 Last modified: 2024-06-05 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Structural basis for broad specificity in alpha-lytic protease mutants. Biochemistry, 30, 1991
7API	THE S VARIANT OF HUMAN ALPHA1-ANTITRYPSIN, STRUCTURE AND IMPLICATIONS FOR FUNCTION AND METABOLISM Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA 1-ANTITRYPSIN, ... Authors: Loebermann, H, Tokuoka, R, Deisenhofer, J, Huber, R. Deposit date: 1988-09-08 Release date: 1990-10-15 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3 Å) Cite: The S variant of human alpha 1-antitrypsin, structure and implications for function and metabolism. Protein Eng., 2, 1989
1HAZ	Snapshots of serine protease catalysis: (C) acyl-enzyme intermediate between porcine pancreatic elastase and human beta-casomorphin-7 jumped to pH 9 for 1 minute Descriptor: BETA-CASOMORPHIN-7, CALCIUM ION, ELASTASE 1, ... Authors: Wilmouth, R.C, Edman, K, Neutze, R, Wright, P.A, Clifton, I.J, Schneider, T.R, Schofield, C.J, Hajdu, J. Deposit date: 2001-04-10 Release date: 2001-08-02 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.4 Å) Cite: X-Ray Snapshots of Serine Protease Catalysis Reveal a Tetrahedral Intermediate Nat.Struct.Biol., 8, 2001
7C4X	Crystal structure of germination protease from the spore-forming bacterium Paenisporosarcina sp. TG-20 in its inactive form Descriptor: germination protease Authors: Lee, J.H, Lee, C.W. Deposit date: 2020-05-18 Release date: 2021-03-31 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural insights into the psychrophilic germinal protease PaGPR and its autoinhibitory loop. J.Microbiol, 58, 2020
1HB0	Snapshots of serine protease catalysis: (D) acyl-enzyme intermediate between porcine pancreatic elastase and human beta-casomorphin-7 jumped to pH 10 for 2 minutes Descriptor: CALCIUM ION, ELASTASE 1, SULFATE ION Authors: Wilmouth, R.C, Edman, K, Neutze, R, Wright, P.A, Clifton, I.J, Schneider, T.R, Schofield, C.J, Hajdu, J. Deposit date: 2001-04-10 Release date: 2001-08-02 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.05 Å) Cite: X-Ray Snapshots of Serine Protease Catalysis Reveal a Tetrahedral Intermediate Nat.Struct.Biol., 8, 2001

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