PDB: 2065 resultsInfo pagesStatus searchChemie searchBIRD

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8FHY	Crystal structure of the SARS-CoV-2 receptor binding domain in complex with neutralizing antibody WRAIR-5021 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, MALONATE ION, ... Authors: Sankhala, R.S, Jensen, J.L, Joyce, M.G. Deposit date: 2022-12-15 Release date: 2024-01-17 Method: X-RAY DIFFRACTION (2.53 Å) Cite: Diverse array of neutralizing antibodies elicited upon Spike Ferritin Nanoparticle vaccination in rhesus macaques. Nat Commun, 15, 2024
8FI9	Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody WRAIR-5001 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Spike protein S1, ... Authors: Sankhala, R.S, Jensen, J.L, Joyce, M.G. Deposit date: 2022-12-15 Release date: 2024-01-17 Method: X-RAY DIFFRACTION (4.2 Å) Cite: Diverse array of neutralizing antibodies elicited upon Spike Ferritin Nanoparticle vaccination in rhesus macaques. Nat Commun, 15, 2024
8TMA	Antibody N3-1 bound to RBD in the up conformation Descriptor: N3-1 Fab heavy chain, N3-1 Fab light chain, Spike glycoprotein Authors: Hsieh, C.-L, McLellan, J.S. Deposit date: 2023-07-29 Release date: 2024-01-17 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: SARS-COV-2 Omicron variants conformationally escape a rare quaternary antibody binding mode. Commun Biol, 6, 2023
8TM1	Antibody N3-1 bound to RBDs in the up and down conformations Descriptor: N3-1 Fab heavy chain, N3-1 Fab light chain, Spike glycoprotein Authors: Hsieh, C.-L, McLellan, J.S. Deposit date: 2023-07-27 Release date: 2024-01-17 Method: ELECTRON MICROSCOPY (2.79 Å) Cite: SARS-COV-2 Omicron variants conformationally escape a rare quaternary antibody binding mode. Commun Biol, 6, 2023
8C5R	Omicron B.1.1.529 2 RBD up conformation Descriptor: Spike glycoprotein Authors: Raghavan, S.S.R, Walker, M.R, Salanti, A, Barfod, L.K, Wang, K.T. Deposit date: 2023-01-10 Release date: 2024-01-24 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Omicron B.1.1.529 2 RBD up conformation To Be Published
8G72	SARS-CoV-2 spike/Nb2 complex with 1 RBD up (local refinement at 5.6 A) Descriptor: Nanosota-2, Spike glycoprotein Authors: Ye, G, Bu, F, Liu, B, Li, F. Deposit date: 2023-02-16 Release date: 2024-01-24 Method: ELECTRON MICROSCOPY (5.6 Å) Cite: Discovery of Nanosota-2, -3, and -4 as super potent and broad-spectrum therapeutic nanobody candidates against COVID-19. J.Virol., 97, 2023
8G74	SARS-CoV-2 spike/Nb3 complex with 1 RBD up and 2 Nb3 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanosota-3, ... Authors: Ye, G, Bu, F, Liu, B, Li, F. Deposit date: 2023-02-16 Release date: 2024-01-24 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: Discovery of Nanosota-2, -3, and -4 as super potent and broad-spectrum therapeutic nanobody candidates against COVID-19. J.Virol., 97, 2023
8G73	SARS-CoV-2 spike/Nb3 complex with 2 RBDs up and 3 Nb3 bound at 2.5 A Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanosota-3, ... Authors: Ye, G, Bu, F, Liu, B, Li, F. Deposit date: 2023-02-16 Release date: 2024-01-24 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: Discovery of Nanosota-2, -3, and -4 as super potent and broad-spectrum therapeutic nanobody candidates against COVID-19. J.Virol., 97, 2023
8G75	SARS-CoV-2 spike/Nb4 complex with 2 RBDs up and 3 Nb4 bound Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanosota-4, ... Authors: Ye, G, Bu, F, Liu, B, Li, F. Deposit date: 2023-02-16 Release date: 2024-01-24 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Discovery of Nanosota-2, -3, and -4 as super potent and broad-spectrum therapeutic nanobody candidates against COVID-19. J.Virol., 97, 2023
8K3K	The crystal structure of nanobody Nb4 in complex with receptor binding domain (RBD) of BA.1 Spike protein Descriptor: Nanobody Nb4, Spike protein S1 Authors: Wang, H.Y, Xu, W.Q. Deposit date: 2023-07-16 Release date: 2024-01-24 Method: X-RAY DIFFRACTION (2.43 Å) Cite: A potent and broad-spectrum neutralizing nanobody for SARS-CoV-2 viruses, including all major Omicron strains. MedComm (2020), 4, 2023
8U1G	Prefusion-stabilized SARS-CoV-2 S2 subunit Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S2 Authors: Hsieh, C.-L, McLellan, J.S. Deposit date: 2023-08-31 Release date: 2024-01-24 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Structure of prefusion-stabilized SARS-CoV-2 S2-only antigen To Be Published
8TYJ	Crystal structure of SARS-CoV-2 nsp10/nsp16 complex with bound SAH Descriptor: 2'-O-methyltransferase, GLYCEROL, Non-structural protein 10, ... Authors: Patel, K.P, Bruner, S.D. Deposit date: 2023-08-25 Release date: 2024-01-24 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structure of SARS-CoV-2 nsp10/nsp16 complex with bound SAH To Be Published
8QPR	SARS-CoV-2 S protein bound to human neutralising antibody UZGENT_G5 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, IgG heavy chain - FAB, ... Authors: Remaut, H, Reiter, D, Vandenkerckhove, L, Acar, D.D, Witkowski, W, Gerlo, S. Deposit date: 2023-10-03 Release date: 2024-01-31 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Integrating artificial intelligence-based epitope prediction in a SARS-CoV-2 antibody discovery pipeline: caution is warranted. Ebiomedicine, 100, 2024
8QQ0	SARS-CoV-2 S protein bound to neutralising antibody UZGENT_A3 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Remaut, H, Reiter, D, Vandenkerckhove, L, Acar, D.D, Witkowski, W, Gerlo, S. Deposit date: 2023-10-03 Release date: 2024-01-31 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Integrating artificial intelligence-based epitope prediction in a SARS-CoV-2 antibody discovery pipeline: caution is warranted. Ebiomedicine, 100, 2024
7YP1	Cryo-EM structure of EBV gHgL-gp42 in complex with mAb 10E4 (localized refinement) Descriptor: 10E4 heavy chain, 10E4 light chain, EBV gH, ... Authors: Liu, L, Sun, H, Jiang, Y, Hong, J, Zheng, Q, Li, S, Chen, Y, Xia, N. Deposit date: 2022-08-02 Release date: 2024-01-31 Method: ELECTRON MICROSCOPY (3.54 Å) Cite: Non-overlapping epitopes on the gHgL-gp42 complex for the rational design of a triple-antibody cocktail against EBV infection. Cell Rep Med, 4, 2023
7YOY	Cryo-EM structure of EBV gHgL-gp42 in complex with mAbs 3E8 and 5E3 (localized refinement) Descriptor: 3E8 heavy chain, 3E8 light chain, 5E3 heavy chain, ... Authors: Liu, L, Sun, H, Jiang, Y, Hong, J, Zheng, Q, Li, S, Chen, Y, Xia, N. Deposit date: 2022-08-02 Release date: 2024-01-31 Method: ELECTRON MICROSCOPY (3.64 Å) Cite: Non-overlapping epitopes on the gHgL-gp42 complex for the rational design of a triple-antibody cocktail against EBV infection. Cell Rep Med, 4, 2023
7YP2	Cryo-EM structure of EBV gHgL-gp42 in complex with mAb 6H2 (localized refinement) Descriptor: 6H2 heavy chain, 6H2 light chain, Envelope glycoprotein H Authors: Liu, L, Sun, H, Jiang, Y, Hong, J, Zheng, Q, Li, S, Chen, Y, Xia, N. Deposit date: 2022-08-02 Release date: 2024-01-31 Method: ELECTRON MICROSCOPY (3.52 Å) Cite: Non-overlapping epitopes on the gHgL-gp42 complex for the rational design of a triple-antibody cocktail against EBV infection. Cell Rep Med, 4, 2023
8PFK	RNA structure with 1-methylpseudoridine, C2 space group Descriptor: MAGNESIUM ION, RNA (12-mer) Authors: Spingler, B, McAuley, K, Nievergelt, P, Thorn, A. Deposit date: 2023-06-16 Release date: 2024-01-31 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.321 Å) Cite: RNA oligomers at atomic resolution containing 1-methylpseudouridine, an essential building block of mRNA vaccines. Chemmedchem, 19, 2024
8PFQ	RNA structure with 1-methylpseudoridine, P1 space group Descriptor: Chains: A,B, MAGNESIUM ION Authors: Spingler, B, McAuley, K, Nievergelt, P, Thorn, A. Deposit date: 2023-06-16 Release date: 2024-01-31 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.01 Å) Cite: RNA oligomers at atomic resolution containing 1-methylpseudouridine, an essential building block of mRNA vaccines. Chemmedchem, 19, 2024
8HPV	Cryo-EM structure of SARS-CoV-2 Omicron Prototype S-trimer in complex with fab L4.65 and L5.34 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S2', fab L4.65, ... Authors: Gao, G.F, Liu, S. Deposit date: 2022-12-13 Release date: 2024-01-31 Last modified: 2024-05-08 Method: ELECTRON MICROSCOPY (2.65 Å) Cite: Dosing interval regimen shapes potency and breadth of antibody repertoire after vaccination of SARS-CoV-2 RBD protein subunit vaccine. Cell Discov, 9, 2023
8HP9	Cryo-EM structure of SARS-CoV-2 Omicron BA.2 S-trimer in complex with fab L4.65 and L5.34 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S2', fab L4.65, ... Authors: Gao, G.F, Liu, S. Deposit date: 2022-12-12 Release date: 2024-01-31 Method: ELECTRON MICROSCOPY (2.75 Å) Cite: Dosing interval regimen shapes potency and breadth of antibody repertoire after vaccination of SARS-CoV-2 RBD protein subunit vaccine. Cell Discov, 9, 2023
8HPQ	Cryo-EM structure of SARS-CoV-2 Omicron BA.4 S-trimer in complex with fab L4.65 and L5.34 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S2', fab L4.65, ... Authors: Gao, G.F, Liu, S. Deposit date: 2022-12-12 Release date: 2024-01-31 Method: ELECTRON MICROSCOPY (2.85 Å) Cite: Dosing interval regimen shapes potency and breadth of antibody repertoire after vaccination of SARS-CoV-2 RBD protein subunit vaccine. Cell Discov, 9, 2023
8TOU	ACE2-peptide 2 complex crystal form 3 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... Authors: Franck, C, Payne, R.J, Christie, M. Deposit date: 2023-08-04 Release date: 2024-02-07 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Discovery of High Affinity Cyclic Peptide Ligands for Human ACE2 with SARS-CoV-2 Entry Inhibitory Activity. Acs Chem.Biol., 19, 2024
8TYL	Structural and biochemical rationale for Beta variant protein booster vaccine broad cross-neutralization of SARS-CoV-2 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein Authors: Bruch, E.M, Rak, A. Deposit date: 2023-08-25 Release date: 2024-02-07 Method: ELECTRON MICROSCOPY (2.85 Å) Cite: Structural and biochemical rationale for Beta variant protein booster vaccine broad cross-neutralization of SARS-CoV-2. Sci Rep, 14, 2024
8TOR	ACE2-peptide 2 complex Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Christie, M, Payne, R.J. Deposit date: 2023-08-03 Release date: 2024-02-07 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Discovery of High Affinity Cyclic Peptide Ligands for Human ACE2 with SARS-CoV-2 Entry Inhibitory Activity. Acs Chem.Biol., 19, 2024

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