8G74

SARS-CoV-2 spike/Nb3 complex with 1 RBD up and 2 Nb3

Summary for 8G74

• Entry DOI: 10.2210/pdb8g74/pdb
• EMDB information: 29792 29793 29794 29795 29796 29797 29798 29799 29802 29803 29804 29805 29806
• Descriptor: Nanosota-3, Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: sars-cov-2, viral protein-immune system complex, nanobody, viral protein/immune system
• Biological source: Vicugna pacos (alpaca); More
• Total number of polymer chains: 5
• Total formula weight: 450468.89

Authors

Ye, G.,Bu, F.,Liu, B.,Li, F. (deposition date: 2023-02-16, release date: 2024-01-24)

• Primary citation: Ye, G.,Pan, R.,Bu, F.,Zheng, J.,Mendoza, A.,Wen, W.,Du, L.,Spiller, B.,Wadzinski, B.E.,Liu, B.,Perlman, S.,Li, F.; Discovery of Nanosota-2, -3, and -4 as super potent and broad-spectrum therapeutic nanobody candidates against COVID-19.; J.Virol., 97:e0144823-e0144823, 2023; PubMed: 37855638; DOI: 10.1128/jvi.01448-23

Experimental method

ELECTRON MICROSCOPY (2.5 Å)