8HPV

Cryo-EM structure of SARS-CoV-2 Omicron Prototype S-trimer in complex with fab L4.65 and L5.34

Summary for 8HPV

• Entry DOI: 10.2210/pdb8hpv/pdb
• EMDB information: 34945
• Descriptor: Spike protein S2', fab L5.34, fab L4.65, ... (6 entities in total)
• Functional Keywords: sars-cov-2, omicron prototype s-trimer, cryo-em structure, fab, immune system/viral protein, immune system-viral protein complex
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2); More
• Total number of polymer chains: 15
• Total formula weight: 664926.21

Authors

Gao, G.F.,Liu, S. (deposition date: 2022-12-13, release date: 2024-01-31, Last modification date: 2024-05-08)

• Primary citation: Guo, S.,Zheng, Y.,Gao, Z.,Duan, M.,Liu, S.,Du, P.,Xu, X.,Xu, K.,Zhao, X.,Chai, Y.,Wang, P.,Zhao, Q.,Gao, G.F.,Dai, L.; Dosing interval regimen shapes potency and breadth of antibody repertoire after vaccination of SARS-CoV-2 RBD protein subunit vaccine.; Cell Discov, 9:79-79, 2023; PubMed: 37507370; DOI: 10.1038/s41421-023-00585-5

Experimental method

ELECTRON MICROSCOPY (2.65 Å)