8HPV
Cryo-EM structure of SARS-CoV-2 Omicron Prototype S-trimer in complex with fab L4.65 and L5.34
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, F, K (A, B, C) | Spike protein S2' | polymer | 1134 | 125606.2 | 3 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | |
| 2 | B, I, N (M, E, R) | fab L5.34 | polymer | 225 | 23721.5 | 3 | Homo sapiens | ||
| 3 | C, J, O (N, F, S) | fab L5.34 | polymer | 216 | 23379.9 | 3 | Homo sapiens | ||
| 4 | D, G, L (H, P, I) | fab L4.65 | polymer | 231 | 24953.9 | 3 | Homo sapiens | ||
| 5 | E, H, M (L, Q, J) | fab L4.65 | polymer | 215 | 23556.1 | 3 | Homo sapiens | ||
| 6 | P, Q, R (D, G, K) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) |
Sequence modifications
A, B, C: 14 - 1147 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Pro 817 | Phe 817 | conflict |
| Pro 892 | Ala 892 | conflict |
| Pro 899 | Ala 899 | conflict |
| Pro 942 | Ala 942 | conflict |
| Pro 986 | Lys 986 | conflict |
| Pro 987 | Val 987 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 15 |
| Total formula weight | 663653.0 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1273.2 | |
| All* | Total formula weight | 664926.2 |
