PDB: 98225 resultsInfo pagesStatus searchChemie searchBIRD

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7TPR	Camel nanobodies 7A3 and 8A2 broadly neutralize SARS-CoV-2 variants Descriptor: Nanobody 7A3, Nanobody 8A2, Spike glycoprotein Authors: Butay, K.J, Zhu, J, Dandey, V.P, Hong, J, Kwon, H.J, Chen, C.Z, Duan, Z, Li, D, Ren, H, Liang, T, Martin, N, Esposito, D, Ortega-Rodriguez, U, Xu, M, Xie, H, Ho, M, Cachau, R, Borgnia, M.J. Deposit date: 2022-01-25 Release date: 2022-04-20 Method: ELECTRON MICROSCOPY (2.39 Å) Cite: Camel nanobodies broadly neutralize SARS-CoV-2 variants bioRxiv, 2021
7U72	Human DNA polymerase eta-DNA ternary mismatch complex:ground state at pH7.0 (K+ MES) with 1 Ca2+ ion Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... Authors: Chang, C, Gao, Y. Deposit date: 2022-03-07 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.53 Å) Cite: In crystallo observation of three metal ion promoted DNA polymerase misincorporation. Nat Commun, 13, 2022
7U76	Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 0.5 mM Mn2+ for 1800s then with 10 mM Mn2+ for 300s Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*())-3'), ... Authors: Chang, C, Gao, Y. Deposit date: 2022-03-07 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.69 Å) Cite: In crystallo observation of three metal ion promoted DNA polymerase misincorporation. Nat Commun, 13, 2022
6BCA	A Complex between PH Domain of LbcRhoGEF (AKAP-Lbc) and Activated RhoA Bound to a GTP Analog Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, A-kinase anchor protein 13, MAGNESIUM ION, ... Authors: Sternweis, P.C, Chen, Z. Deposit date: 2017-10-20 Release date: 2017-12-13 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.995 Å) Cite: Crystal structures of the PH domains from Lbc family of RhoGEFs bound to activated RhoA GTPase. Data Brief, 17, 2018
7U7C	Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 1.0 mM Mg2+ for 300s Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*G)-3'), ... Authors: Chang, C, Gao, Y. Deposit date: 2022-03-07 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.55 Å) Cite: In crystallo observation of three metal ion promoted DNA polymerase misincorporation. Nat Commun, 13, 2022
6BGA	2B4 I-Ek TCR-MHC complex with affinity-enhancing Velcro peptide Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2B4 peptide,MHC I-Ek B chain, ... Authors: Gee, M.H, Sibener, L.V, Birnbaum, M.E, Jude, K.M, Garcia, K.C. Deposit date: 2017-10-27 Release date: 2018-07-18 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.307 Å) Cite: Stress-testing the relationship between T cell receptor/peptide-MHC affinity and cross-reactivity using peptide velcro. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7U7J	Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 10.0 mM Mn2+ for 300s Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*G)-3'), ... Authors: Chang, C, Gao, Y. Deposit date: 2022-03-07 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.58 Å) Cite: In crystallo observation of three metal ion promoted DNA polymerase misincorporation. Nat Commun, 13, 2022
7U7W	Human DNA polymerase eta-DNA-dGMPNPP ternary mismatch complex in 1.0 mM Mg2+ for 600s Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... Authors: Chang, C, Gao, Y. Deposit date: 2022-03-07 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.66 Å) Cite: In crystallo observation of three metal ion promoted DNA polymerase misincorporation. Nat Commun, 13, 2022
7U7A	Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 1.0 mM Mg2+ for 200s Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*G)-3'), ... Authors: Chang, C, Gao, Y. Deposit date: 2022-03-07 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.58 Å) Cite: In crystallo observation of three metal ion promoted DNA polymerase misincorporation. Nat Commun, 13, 2022
6ORA	An Unexpected Intermediate in the Reaction Catalyzed by Quinolinate Synthase Descriptor: (2~{Z})-2-(1-oxidanyl-3-oxidanylidene-propyl)iminobutanedioic acid, 2-hydroxy-N-[(1S)-1-hydroxy-3-oxopropyl]-L-aspartic acid, ACETATE ION, ... Authors: Esakova, O.A, Grove, T.L, Silakov, A, Yennawar, N.H, Booker, S.J. Deposit date: 2019-04-29 Release date: 2019-08-21 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.2 Å) Cite: An Unexpected Species Determined by X-ray Crystallography that May Represent an Intermediate in the Reaction Catalyzed by Quinolinate Synthase. J.Am.Chem.Soc., 141, 2019
7U7D	Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 10.0 mM Mn2+ for 30s Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... Authors: Chang, C, Gao, Y. Deposit date: 2022-03-07 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.57 Å) Cite: In crystallo observation of three metal ion promoted DNA polymerase misincorporation. Nat Commun, 13, 2022
7U7R	Human DNA polymerase eta-DNA-dGMPNPP ternary mismatch complex:no Me2+ soaking Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... Authors: Chang, C, Gao, Y. Deposit date: 2022-03-07 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.64 Å) Cite: In crystallo observation of three metal ion promoted DNA polymerase misincorporation. Nat Commun, 13, 2022
7U7Y	Human DNA polymerase eta-DNA-dGMPNPP ternary mismatch complex in 0.06 mM Mn2+ for 600s Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... Authors: Chang, C, Gao, Y. Deposit date: 2022-03-07 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.78 Å) Cite: In crystallo observation of three metal ion promoted DNA polymerase misincorporation. Nat Commun, 13, 2022
7TVF	Crystal structure of the SHOC2-MRAS-PP1CA (SMP) complex to a resolution of 2.17 Angstrom Descriptor: CHLORIDE ION, GLYCEROL, Leucine-rich repeat protein SHOC-2, ... Authors: Bonsor, D.A, Simanshu, D.K. Deposit date: 2022-02-04 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.17 Å) Cite: Structure of the SHOC2-MRAS-PP1C complex provides insights into RAF activation and Noonan syndrome. Nat.Struct.Mol.Biol., 29, 2022
7U78	Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 1.0 mM Mg2+ for 80s Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*G)-3'), ... Authors: Chang, C, Gao, Y. Deposit date: 2022-03-07 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.61 Å) Cite: In crystallo observation of three metal ion promoted DNA polymerase misincorporation. Nat Commun, 13, 2022
7U7F	Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 10.0 mM Mn2+ for 90s Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*G)-3'), ... Authors: Chang, C, Gao, Y. Deposit date: 2022-03-07 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.65 Å) Cite: In crystallo observation of three metal ion promoted DNA polymerase misincorporation. Nat Commun, 13, 2022
7U7T	Human DNA polymerase eta-DNA-dGMPNPP ternary mismatch complex in 0.05 mM Mg2+ for 600s Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... Authors: Chang, C, Gao, Y. Deposit date: 2022-03-07 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.55 Å) Cite: In crystallo observation of three metal ion promoted DNA polymerase misincorporation. Nat Commun, 13, 2022
7U80	Human DNA polymerase eta-DNA-dGMPNPP ternary mismatch complex in 0.25 mM Mn2+ for 600s Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... Authors: Chang, C, Gao, Y. Deposit date: 2022-03-07 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.83 Å) Cite: In crystallo observation of three metal ion promoted DNA polymerase misincorporation. Nat Commun, 13, 2022
7U75	Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 0.5 mM Mn2+ for 1800s then with 10 mM Mn2+ for 90s Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... Authors: Chang, C, Gao, Y. Deposit date: 2022-03-07 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.55 Å) Cite: In crystallo observation of three metal ion promoted DNA polymerase misincorporation. Nat Commun, 13, 2022
7U7E	Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 10.0 mM Mn2+ for 60s Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... Authors: Chang, C, Gao, Y. Deposit date: 2022-03-07 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.58 Å) Cite: In crystallo observation of three metal ion promoted DNA polymerase misincorporation. Nat Commun, 13, 2022
7U7L	Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 1.0 mM Mg2+ for 300s with flipped-out product Descriptor: DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... Authors: Chang, C, Gao, Y. Deposit date: 2022-03-07 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.47 Å) Cite: In crystallo observation of three metal ion promoted DNA polymerase misincorporation. Nat Commun, 13, 2022
7U7Z	Human DNA polymerase eta-DNA-dGMPNPP ternary mismatch complex in 0.12 mM Mn2+ for 600s Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... Authors: Chang, C, Gao, Y. Deposit date: 2022-03-07 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.67 Å) Cite: In crystallo observation of three metal ion promoted DNA polymerase misincorporation. Nat Commun, 13, 2022
7U74	Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 0.5 mM Mn2+ for 1800s then with 10 mM Mn2+ for 30s Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... Authors: Chang, C, Gao, Y. Deposit date: 2022-03-07 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.52 Å) Cite: In crystallo observation of three metal ion promoted DNA polymerase misincorporation. Nat Commun, 13, 2022
7U79	Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 1.0 mM Mg2+ for 140s Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*G)-3'), ... Authors: Chang, C, Gao, Y. Deposit date: 2022-03-07 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.69 Å) Cite: In crystallo observation of three metal ion promoted DNA polymerase misincorporation. Nat Commun, 13, 2022
7U7I	Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 10.0 mM Mn2+ for 180s Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*G)-3'), ... Authors: Chang, C, Gao, Y. Deposit date: 2022-03-07 Release date: 2022-05-04 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.57 Å) Cite: In crystallo observation of three metal ion promoted DNA polymerase misincorporation. Nat Commun, 13, 2022

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