8UEU
| In-situ complex I, Deactive class03 | Descriptor: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ... | Authors: | Zheng, W, Zhu, J, Zhang, K. | Deposit date: | 2023-10-02 | Release date: | 2024-06-19 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | High-resolution in situ structures of mammalian respiratory supercomplexes. Nature, 631, 2024
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6NBN
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1BL1
| PTH RECEPTOR N-TERMINUS FRAGMENT, NMR, 1 STRUCTURE | Descriptor: | PARATHYROID HORMONE RECEPTOR | Authors: | Pellegrini, M, Bisello, A, Rosenblatt, M, Chorev, M, Mierke, D.F. | Deposit date: | 1998-07-22 | Release date: | 1999-03-30 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Binding domain of human parathyroid hormone receptor: from conformation to function. Biochemistry, 37, 1998
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6KCC
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6KCB
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8E31
| Purification of Enterovirus A71, strain 4643, WT capsid | Descriptor: | Genome polyprotein, VP1, VP3 | Authors: | Catching, A, Capponi, S, Andino, R. | Deposit date: | 2022-08-16 | Release date: | 2023-08-30 | Last modified: | 2023-12-06 | Method: | ELECTRON MICROSCOPY (14 Å) | Cite: | A tradeoff between enterovirus A71 particle stability and cell entry. Nat Commun, 14, 2023
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8AZ5
| IAPP S20G plateau-phase fibril polymorph 4PF-CU | Descriptor: | Islet amyloid polypeptide | Authors: | Wilkinson, M, Xu, Y, Gallardo, R, Radford, S.E, Ranson, N.A. | Deposit date: | 2022-09-05 | Release date: | 2024-01-10 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | Structural evolution of fibril polymorphs during amyloid assembly. Cell, 186, 2023
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8AZ4
| IAPP S20G plateau-phase fibril polymorph 2PF-L | Descriptor: | Islet amyloid polypeptide | Authors: | Wilkinson, M, Xu, Y, Gallardo, R, Radford, S.E, Ranson, N.A. | Deposit date: | 2022-09-05 | Release date: | 2024-01-10 | Method: | ELECTRON MICROSCOPY (2.2 Å) | Cite: | Structural evolution of fibril polymorphs during amyloid assembly. Cell, 186, 2023
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1QMQ
| Optical detection of cytochrome P450 by sensitizer-linked substrates | Descriptor: | ACETATE ION, CYTOCHROME P450, DELTA-BIS(2,2'-BIPYRIDINE)-(5-METHYL-2-2'-BIPYRIDINE)-C9-ADAMANTANE RUTHENIUM (II), ... | Authors: | Crane, B.R, Dmochowski, I.J, Gray, H.B. | Deposit date: | 1999-10-05 | Release date: | 2000-10-06 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Optical Detection of Cytochrome P450 by Sensitizer-Linked Substrates Proc.Natl.Acad.Sci.USA, 96, 1999
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6KJO
| The microtubule-binding domains of yeast cytoplasmic dynein in the low affinity state | Descriptor: | Dynein heavy chain, cytoplasmic | Authors: | Nishida, N, Komori, Y, Takarada, O, Watanabe, A, Tamura, S, Kubo, S, Shimada, I, Kikkawa, M. | Deposit date: | 2019-07-22 | Release date: | 2020-03-18 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structural basis for two-way communication between dynein and microtubules. Nat Commun, 11, 2020
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6KCA
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6KCD
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1AXP
| DNA DUPLEX CONTAINING A PURINE-RICH STRAND, NMR, 6 STRUCTURES | Descriptor: | DNA (D(GAAGAGAAGC)(DOT)D(GCTTCTCTTC)) | Authors: | Gyi, J.I, Lane, A.N, Conn, G.L, Brown, T. | Deposit date: | 1997-10-17 | Release date: | 1998-04-22 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structures of DNA.RNA hybrids with purine-rich and pyrimidine-rich strands: comparison with the homologous DNA and RNA duplexes. Biochemistry, 37, 1998
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1D7N
| SOLUTION STRUCTURE ANALYSIS OF THE MASTOPARAN WITH DETERGENTS | Descriptor: | PROTEIN (WASP VENOM PEPTIDE (MASTOPARAN)) | Authors: | Hori, Y, Demura, M, Iwadate, M, Niidome, T, Aoyagi, H, Asakura, T. | Deposit date: | 1999-10-19 | Release date: | 2001-06-20 | Last modified: | 2022-02-16 | Method: | SOLUTION NMR | Cite: | Interaction of mastoparan with membranes studied by 1H-NMR spectroscopy in detergent micelles and by solid-state 2H-NMR and 15N-NMR spectroscopy in oriented lipid bilayers. Eur.J.Biochem., 268, 2001
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7MJP
| Vascular KATP channel: Kir6.1 SUR2B propeller-like conformation 2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Sung, M.W, Shyng, S.L. | Deposit date: | 2021-04-20 | Release date: | 2021-10-13 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Vascular K ATP channel structural dynamics reveal regulatory mechanism by Mg-nucleotides. Proc.Natl.Acad.Sci.USA, 118, 2021
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6KJN
| The microtubule-binding domains of yeast cytoplasmic dynein in the high affinity state | Descriptor: | Dynein heavy chain, cytoplasmic | Authors: | Nishida, N, Komori, Y, Takarada, O, Watanabe, A, Tamura, S, Kubo, S, Shimada, I, Kikkawa, M. | Deposit date: | 2019-07-22 | Release date: | 2020-03-18 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structural basis for two-way communication between dynein and microtubules. Nat Commun, 11, 2020
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1CE5
| BOVINE PANCREAS BETA-TRYPSIN IN COMPLEX WITH BENZAMIDINE | Descriptor: | BENZAMIDINE, CALCIUM ION, CHLORIDE ION, ... | Authors: | Ota, N, Stroupe, C, Ferreira-Da-Silva, J.M.S, Shah, S.S, Mares-Guia, M, Brunger, A.T. | Deposit date: | 1999-03-16 | Release date: | 1999-03-23 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Non-Boltzmann thermodynamic integration (NBTI) for macromolecular systems: relative free energy of binding of trypsin to benzamidine and benzylamine. Proteins, 37, 1999
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6KHV
| Solution Structure of the CS2 Domain of USP19 | Descriptor: | Ubiquitin carboxyl-terminal hydrolase 19 | Authors: | Xue, W, Hu, H.Y. | Deposit date: | 2019-07-16 | Release date: | 2020-07-22 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Domain interactions reveal auto-inhibition of the deubiquitinating enzyme USP19 and its activation by HSP90 in the modulation of huntingtin aggregation. Biochem.J., 477, 2020
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6JXV
| SUMO1 bound to phosphorylated SLS4-SIM peptide from ICP0 | Descriptor: | Phosphorylated SLS4-SIM from ubiquitin E3 ligase ICP0, Small ubiquitin-related modifier | Authors: | Hembram, D.S.S, Negi, H, Shet, D, Das, R. | Deposit date: | 2019-04-25 | Release date: | 2020-02-05 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | The Viral SUMO-Targeted Ubiquitin Ligase ICP0 is Phosphorylated and Activated by Host Kinase Chk2. J.Mol.Biol., 432, 2020
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6JXX
| SUMO2 bound to phosphorylated SLS4-SIM peptide from ICP0 | Descriptor: | Phosphorylated SLS4 from E3 ubiquitin ligase ICP0, Small ubiquitin-related modifier 2 | Authors: | Hembram, D.S.S, Negi, H, Shet, D, Das, R. | Deposit date: | 2019-04-25 | Release date: | 2020-02-05 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | The Viral SUMO-Targeted Ubiquitin Ligase ICP0 is Phosphorylated and Activated by Host Kinase Chk2. J.Mol.Biol., 432, 2020
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6K84
| Structure of anti-prion RNA aptamer | Descriptor: | RNA (25-MER) | Authors: | Mashima, T, Lee, J.H, Hayashi, T, Nagata, T, Kinoshita, M, Katahira, M. | Deposit date: | 2019-06-11 | Release date: | 2020-04-01 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Development and structural determination of an anti-PrPCaptamer that blocks pathological conformational conversion of prion protein. Sci Rep, 10, 2020
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6OSA
| human Neurotensin Receptor 1 (hNTSR1) - Gi1 Protein Complex in non-canonical conformation (NC state) | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Kato, H.E, Zhang, Y, Kobilka, B.K, Skiniotis, G. | Deposit date: | 2019-05-01 | Release date: | 2019-07-10 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Conformational transitions of a neurotensin receptor 1-Gi1complex. Nature, 572, 2019
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8XZF
| Cryo-EM structure of the WN561-bound human APLNR-Gi complex | Descriptor: | Apelin receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Wang, W, Ji, S, Zhang, Y. | Deposit date: | 2024-01-21 | Release date: | 2024-03-20 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structure-based design of non-hypertrophic apelin receptor modulator. Cell, 187, 2024
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8XZJ
| Cryo-EM structure of the WN353-bound human APLNR-Gi complex | Descriptor: | Apelin receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Wang, W, Ji, S, Zhang, Y. | Deposit date: | 2024-01-21 | Release date: | 2024-03-20 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structure-based design of non-hypertrophic apelin receptor modulator. Cell, 187, 2024
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7Y1Q
| 5.0 angstrom cryo-EM structure of transmembrane regions of mouse Basigin/MCT1 in complex with antibody 6E7F1 | Descriptor: | Isoform 2 of Basigin, Monocarboxylate transporter 1 | Authors: | Zhang, H, Yang, X, Xue, Y, Huang, Y, Mo, X, Zhang, H, Li, N, Gao, N, Li, X, Wang, S, Gao, Y, Liao, J. | Deposit date: | 2022-06-08 | Release date: | 2023-06-14 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (5.03 Å) | Cite: | Allosteric modulation of monocarboxylate transporters 1 and 4 by targeting their chaperon Basigin-2 To Be Published
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