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1UK0
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Crystal structure of catalytic domain of human poly(ADP-ribose) polymerase with a novel inhibitor
Descriptor: 2-{3-[4-(4-FLUOROPHENYL)-3,6-DIHYDRO-1(2H)-PYRIDINYL]PROPYL}-8-METHYL-4(3H)-QUINAZOLINONE, Poly [ADP-ribose] polymerase-1
Authors:Kinoshita, T.
Deposit date:2003-08-13
Release date:2004-01-27
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Inhibitor-induced structural change of the active site of human poly(ADP-ribose) polymerase.
Febs Lett., 556, 2004
1RHO
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BU of 1rho by Molmil
STRUCTURE OF RHO GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR
Descriptor: RHO GDP-DISSOCIATION INHIBITOR 1, SULFATE ION
Authors:Keep, N.H, Moody, P.C.E, Roberts, G.C.K.
Deposit date:1996-10-12
Release date:1997-10-15
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A modulator of rho family G proteins, rhoGDI, binds these G proteins via an immunoglobulin-like domain and a flexible N-terminal arm.
Structure, 5, 1997
1TE6
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BU of 1te6 by Molmil
Crystal Structure of Human Neuron Specific Enolase at 1.8 angstrom
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Gamma enolase, ...
Authors:Chai, G, Brewer, J, Lovelace, L, Aoki, T, Minor, W, Lebioda, L.
Deposit date:2004-05-24
Release date:2004-09-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Expression, Purification and the 1.8 A Resolution Crystal Structure of Human Neuron Specific Enolase
J.Mol.Biol., 341, 2004
1TEV
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BU of 1tev by Molmil
Crystal structure of the human UMP/CMP kinase in open conformation
Descriptor: SULFATE ION, UMP-CMP kinase
Authors:Segura-Pena, D, Sekulic, N, Ort, S, Konrad, M, Lavie, A.
Deposit date:2004-05-25
Release date:2004-06-22
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Substrate-induced Conformational Changes in Human UMP/CMP Kinase.
J.Biol.Chem., 279, 2004
1UPW
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BU of 1upw by Molmil
Crystal structure of the human Liver X receptor beta ligand binding domain in complex with a synthetic agonist
Descriptor: N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE, OXYSTEROLS RECEPTOR LXR-BETA
Authors:Hoerer, S, Schmid, A, Heckel, A, Budzinski, R.M, Nar, H.
Deposit date:2003-10-13
Release date:2004-10-20
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of the Human Liver X Receptor Beta Ligand-Binding Domain in Complex with a Synthetic Agonist
J.Mol.Biol., 334, 2003
1TYQ
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BU of 1tyq by Molmil
Crystal structure of Arp2/3 complex with bound ATP and calcium
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin-related Protein 2, Actin-related protein 3, ...
Authors:Nolen, B.J, Littlefield, R.S, Pollard, T.D.
Deposit date:2004-07-08
Release date:2004-11-09
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal structures of actin-related protein 2/3 complex with bound ATP or ADP
Proc.Natl.Acad.Sci.Usa, 101, 2004
1UBD
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BU of 1ubd by Molmil
CO-CRYSTAL STRUCTURE OF HUMAN YY1 ZINC FINGER DOMAIN BOUND TO THE ADENO-ASSOCIATED VIRUS P5 INITIATOR ELEMENT
Descriptor: DNA (5'-D(*AP*GP*GP*GP*TP*CP*TP*CP*CP*AP*TP*TP*TP*TP*GP*AP*A P*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*TP*TP*CP*AP*AP*AP*AP*TP*GP*GP*AP*GP*AP*C P*CP*CP*T)-3'), PROTEIN (YY1 ZINC FINGER DOMAIN), ...
Authors:Houbaviy, H.B, Usheva, A, Shenk, T, Burley, S.K.
Deposit date:1996-10-04
Release date:1996-12-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Cocrystal structure of YY1 bound to the adeno-associated virus P5 initiator.
Proc.Natl.Acad.Sci.USA, 93, 1996
1U76
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BU of 1u76 by Molmil
Crystal structure of hPCNA bound to residues 452-466 of the DNA polymerase-delta-p66 subunit
Descriptor: KANRQVSITGFFQRK peptide from DNA polymerase delta subunit 3, Proliferating cell nuclear antigen
Authors:Bruning, J.B, Shamoo, Y.
Deposit date:2004-08-02
Release date:2004-12-14
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and Thermodynamic Analysis of Human PCNA with Peptides Derived from DNA Polymerase-delta p66 Subunit and Flap Endonuclease-1.
Structure, 12, 2004
1UK5
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BU of 1uk5 by Molmil
Solution structure of the Murine BAG domain of Bcl2-associated athanogene 3
Descriptor: BAG-family molecular chaperone regulator-3
Authors:Hatta, R, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-08-19
Release date:2004-02-19
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:The C-terminal BAG domain of BAG5 induces conformational changes of the Hsp70 nucleotide-binding domain for ADP-ATP exchange
Structure, 18, 2010
1UL1
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BU of 1ul1 by Molmil
Crystal structure of the human FEN1-PCNA complex
Descriptor: Flap endonuclease-1, MAGNESIUM ION, Proliferating cell nuclear antigen
Authors:Sakurai, S, Kitano, K, Yamaguchi, H, Hamada, K, Okada, K, Fukuda, K, Uchida, M, Ohtsuka, E, Morioka, H, Hakoshima, T.
Deposit date:2003-09-05
Release date:2005-03-01
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for recruitment of human flap endonuclease 1 to PCNA
EMBO J., 24, 2005
1UPV
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BU of 1upv by Molmil
Crystal structure of the human Liver X receptor beta ligand binding domain in complex with a synthetic agonist
Descriptor: N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE, OXYSTEROLS RECEPTOR LXR-BETA
Authors:Hoerer, S, Schmid, A, Heckel, A, Budzinski, R.M, Nar, H.
Deposit date:2003-10-13
Release date:2004-10-20
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of the Human Liver X Receptor Beta Ligand-Binding Domain in Complex with a Synthetic Agonist
J.Mol.Biol., 334, 2003
1SSF
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BU of 1ssf by Molmil
Solution structure of the mouse 53BP1 fragment (residues 1463-1617)
Descriptor: Transformation related protein 53 binding protein 1
Authors:Charier, G, Couprie, J, Alpha-Bazin, B, Meyer, V, Quemeneur, E, Guerois, R, Callebaut, I, Gilquin, B, Zinn-Justin, S.
Deposit date:2004-03-24
Release date:2004-09-14
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The Tudor Tandem of 53BP1; A New Structural Motif Involved in DNA and RG-Rich Peptide Binding
Structure, 12, 2004
1VBS
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BU of 1vbs by Molmil
STRUCTURE OF CYCLOPHILIN COMPLEXED WITH (D)ALA CONTAINING TETRAPEPTIDE
Descriptor: CYCLOPHILIN A, TETRAPEPTIDE
Authors:Zhao, Y, Chen, Y, Schutkowski, M, Fischer, G, Ke, H.
Deposit date:1998-06-16
Release date:1999-01-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mapping the stereospecificity of peptidyl prolyl cis/trans isomerases.
FEBS Lett., 432, 1998
1VBT
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BU of 1vbt by Molmil
Structure of cyclophilin complexed with sulfur-substituted tetrapeptide AAPF
Descriptor: CYCLOPHILIN A, SULFUR-SUBSTITUTED TETRAPEPTIDE
Authors:Zhao, Y, Chen, Y, Schutkowski, M, Fischer, G, Ke, H.
Deposit date:1998-06-16
Release date:1999-01-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Insight Into Conversion of Substrate to Inhibitor
To be Published
1T6N
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BU of 1t6n by Molmil
Crystal structure of the N-terminal domain of human UAP56
Descriptor: CITRATE ANION, Probable ATP-dependent RNA helicase
Authors:Zhao, R.
Deposit date:2004-05-06
Release date:2004-08-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Crystal Structure of UAP56, a DExD/H-Box Protein Involved in Pre-mRNA Splicing and mRNA Export
Structure, 12, 2004
1W0U
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BU of 1w0u by Molmil
hTRF2 DNA-binding domain in complex with telomeric DNA.
Descriptor: 5'-D(*CP*TP*AP*AP*CP*CP*CP*TP*AP*AP *CP*CP*CP*TP*AP*GP*A)-3', 5'-D(*TP*CP*TP*AP*GP*GP*GP*TP*TP*AP *GP*GP*GP*TP*TP*AP*G)-3', TELOMERIC REPEAT BINDING FACTOR 2
Authors:Court, R.I, Chapman, L.M, Fairall, L, Rhodes, D.
Deposit date:2004-06-11
Release date:2004-12-22
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:How the Human Telomeric Proteins Trf1 and Trf2 Recognize Telomeric DNA: A View from High-Resolution Crystal Structures
Embo Rep., 6, 2005
1W8M
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BU of 1w8m by Molmil
Enzymatic and Structural Characterisation of Non Peptide Ligand Cyclophilin Complexes
Descriptor: ETHYL OXO(PIPERIDIN-1-YL)ACETATE, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
Authors:Kontopidis, G, Taylor, P, Walkinshaw, M.
Deposit date:2004-09-24
Release date:2004-09-30
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Enzymatic and Structural Characterization of Non-Peptide Ligand-Cyclophilin Complexes
Acta Crystallogr.,Sect.D, 60, 2004
1W8V
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BU of 1w8v by Molmil
Enzymatic and structural characterization of non peptide ligand cyclophilin complexes
Descriptor: PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
Authors:Kontopidis, G, Taylor, P, Walkinshaw, M.
Deposit date:2004-09-28
Release date:2004-09-30
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Enzymatic and Structural Characterization of Non-Peptide Ligand-Cyclophilin Complexes
Acta Crystallogr.,Sect.D, 60, 2004
1WA5
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BU of 1wa5 by Molmil
Structure of the Cse1:Imp-alpha:RanGTP complex
Descriptor: GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, Importin alpha re-exporter, ...
Authors:Stewart, M.
Deposit date:2004-10-23
Release date:2004-12-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for the assembly of a nuclear export complex.
Nature, 432, 2004
1VFC
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BU of 1vfc by Molmil
Solution Structure Of The DNA Complex Of Human Trf2
Descriptor: Short C-rich starnd, Short G-rich strand, Telomeric repeat binding factor 2
Authors:Nishimura, Y, Hanaoka, S.
Deposit date:2004-04-12
Release date:2005-05-17
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Comparison between TRF2 and TRF1 of their telomeric DNA-bound structures and DNA-binding activities
Protein Sci., 14, 2005
1VKX
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BU of 1vkx by Molmil
CRYSTAL STRUCTURE OF THE NFKB P50/P65 HETERODIMER COMPLEXED TO THE IMMUNOGLOBULIN KB DNA
Descriptor: DNA (5'-D(*AP*GP*GP*AP*AP*AP*GP*TP*CP*CP*CP*C)-3'), DNA (5'-D(*TP*GP*GP*GP*GP*AP*CP*TP*TP*TP*CP*C)-3'), PROTEIN (NF-KAPPA B P50 SUBUNIT), ...
Authors:Chen, F, Huang, D.B, Ghosh, G.
Deposit date:1997-09-17
Release date:1998-12-09
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of p50/p65 heterodimer of transcription factor NF-kappaB bound to DNA.
Nature, 391, 1998
1VF9
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BU of 1vf9 by Molmil
Solution Structure Of Human Trf2
Descriptor: Telomeric repeat binding factor 2
Authors:Nishimura, Y, Hanaoka, S.
Deposit date:2004-04-12
Release date:2005-05-17
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Comparison between TRF2 and TRF1 of their telomeric DNA-bound structures and DNA-binding activities
Protein Sci., 14, 2005
5HVK
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BU of 5hvk by Molmil
Crystal structure of LIMK1 mutant D460N in complex with full-length cofilin-1
Descriptor: Cofilin-1, LIM domain kinase 1, MAGNESIUM ION, ...
Authors:Hamill, S, Boggon, T.J.
Deposit date:2016-01-28
Release date:2016-05-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural Basis for Noncanonical Substrate Recognition of Cofilin/ADF Proteins by LIM Kinases.
Mol.Cell, 62, 2016
5HYN
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BU of 5hyn by Molmil
Structure of Human Polycomb Repressive Complex 2 (PRC2) with oncogenic histone H3K27M peptide
Descriptor: H3K27M, Histone-lysine N-methyltransferase EZH2, JARID2 K116me3, ...
Authors:Zhang, Y, Justin, N, Wilson, J.R, Gamblin, S.J.
Deposit date:2016-02-01
Release date:2016-05-11
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural basis of oncogenic histone H3K27M inhibition of human polycomb repressive complex 2.
Nat Commun, 7, 2016
1WF7
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BU of 1wf7 by Molmil
Solution structure of the PDZ domain of Enigma homologue protein
Descriptor: Enigma homologue protein
Authors:Qin, X, Tochio, N, Kigawa, T, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-05-26
Release date:2004-11-26
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the PDZ domain of Enigma homologue protein
To be published

223790

数据于2024-08-14公开中

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