1KJK
 
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6KEA
 | | crystal structure of MBP-tagged REV7-IpaB complex | | Descriptor: | Maltose-binding periplasmic protein,LINKER,hREV7,LINKER,Invasin IpaB,hREV3 | | Authors: | Wang, X, Pernicone, N, Pertz, L, Hua, D.P, Zhang, T.Q, Listovsky, T, Xie, W. | | Deposit date: | 2019-07-04 | | Release date: | 2019-09-11 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | REV7 has a dynamic adaptor region to accommodate small GTPase RAN/ShigellaIpaB ligands, and its activity is regulated by the RanGTP/GDP switch.
J.Biol.Chem., 294, 2019
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3BRJ
 | | Crystal structure of mannitol operon repressor (MtlR) from Vibrio parahaemolyticus RIMD 2210633 | | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, Mannitol operon repressor | | Authors: | Tan, K, Zhou, M, Moy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2007-12-21 | | Release date: | 2008-01-15 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | The mannitol operon repressor MtlR belongs to a new class of transcription regulators in bacteria.
J.Biol.Chem., 284, 2009
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2MLG
 | | Stf76 from the Sulfolobus islandicus plasmid-virus pSSVx | | Descriptor: | Sulfolobus transcription factor 76 aminoacid protein, Stf76 | | Authors: | Farina, B, Russo, L, Fattorusso, R. | | Deposit date: | 2014-02-27 | | Release date: | 2014-03-12 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Structural and functional studies of Stf76 from the Sulfolobus islandicus plasmid-virus pSSVx: a novel peculiar member of the winged helix-turn-helix transcription factor family.
Nucleic Acids Res., 42, 2014
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3ZVN
 | | The structural basis for substrate recognition by mammalian polynucleotide kinase 3' phosphatase | | Descriptor: | 5'-D(*GP*TP*CP*AP*CP)-3', ADENOSINE-5'-DIPHOSPHATE, BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE, ... | | Authors: | Garces, F, Pearl, L.H, Oliver, A.W. | | Deposit date: | 2011-07-25 | | Release date: | 2011-11-16 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | The structural basis for substrate recognition by mammalian polynucleotide kinase 3' phosphatase.
Mol. Cell, 44, 2011
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2EA0
 | | Crystal structure of the DNA repair enzyme endonuclease-VIII (Nei) from E. coli in complex with AP-site containing DNA substrate | | Descriptor: | 5'-D(P*CP*AP*GP*GP*AP*(PED)P*GP*AP*AP*GP*CP*C)-3', 5'-D(P*GP*GP*CP*TP*TP*CP*AP*TP*CP*CP*TP*G)-3', Endonuclease VIII, ... | | Authors: | Golan, G, Zharov, D.O, Grollman, A.P, Shoham, G. | | Deposit date: | 2007-01-29 | | Release date: | 2008-02-26 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Active site plasticity of endonuclease VIII: Conformational changes compensating for different substrate and mutations of critical residues
To be Published
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3P4Y
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3P4X
 | | Helicase domain of reverse gyrase from Thermotoga maritima | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ... | | Authors: | Rudolph, M.G, Klostermeier, D. | | Deposit date: | 2010-10-07 | | Release date: | 2011-06-15 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.41 Å) | | Cite: | The Conformational Flexibility of the Helicase-like Domain from Thermotoga maritima Reverse Gyrase Is Restricted by the Topoisomerase Domain.
Biochemistry, 50, 2011
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4XM5
 | | C. glabrata Slx1. | | Descriptor: | CHLORIDE ION, Structure-specific endonuclease subunit SLX1, ZINC ION | | Authors: | Gaur, V, Wyatt, H.D.M, Komorowska, W, Szczepanowski, R.H, de Sanctis, D, Gorecka, K.M, West, S.C, Nowotny, M. | | Deposit date: | 2015-01-14 | | Release date: | 2015-03-25 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.34 Å) | | Cite: | Structural and Mechanistic Analysis of the Slx1-Slx4 Endonuclease.
Cell Rep, 10, 2015
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7VVY
 | | TRA module of NuA4 | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin-related protein 4, ... | | Authors: | Chen, Z, Qu, K. | | Deposit date: | 2021-11-09 | | Release date: | 2022-08-10 | | Last modified: | 2024-06-26 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structure of the NuA4 acetyltransferase complex bound to the nucleosome.
Nature, 610, 2022
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3M03
 | | Crystal structure of human Orc6 fragment | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Origin recognition complex subunit 6, SULFATE ION | | Authors: | Liu, S.X, Wu, L.J, Sun, J, Wang, H.F, Liu, Y.F. | | Deposit date: | 2010-03-02 | | Release date: | 2011-03-09 | | Last modified: | 2014-03-05 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural analysis of human Orc6 protein reveals a homology with transcription factor TFIIB
Proc.Natl.Acad.Sci.USA, 108, 2011
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5FQD
 | | Structural basis of Lenalidomide induced CK1a degradation by the crl4crbn ubiquitin ligase | | Descriptor: | CASEIN KINASE I ISOFORM ALPHA, DNA DAMAGE-BINDING PROTEIN 1, PROTEIN CEREBLON, ... | | Authors: | Petzold, G, Fischer, E.S, Thoma, N.H. | | Deposit date: | 2015-12-09 | | Release date: | 2016-02-24 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Structural Basis of Lenalidomide-Induced Ck1Alpha Degradation by the Crl4(Crbn) Ubiquitin Ligase.
Nature, 532, 2016
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6W5X
 | | Crystal structure of human polymerase eta complexed with N7-benzylguanine and dCTP* | | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*AP*GP*TP*GP*TP*GP*AP*G)-3'), DNA (5'-D(*CP*AP*TP*(DRG)P*CP*TP*CP*AP*CP*AP*CP*T)-3'), ... | | Authors: | Jung, H, Lee, S. | | Deposit date: | 2020-03-14 | | Release date: | 2021-03-17 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.59 Å) | | Cite: | Crystal structure of human polymerase eta complexed with N7-benzylguanine and dCTP*
To Be Published
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6W7J
 | | Structure of Tdp1 catalytic domain in complex with inhibitor XZ635p | | Descriptor: | 1,2-ETHANEDIOL, 4-{[2-(2-hydroxyphenyl)imidazo[1,2-a]pyridin-3-yl]amino}benzene-1,2-dicarboxylic acid, Tyrosyl-DNA phosphodiesterase 1 | | Authors: | Lountos, G.T, Zhao, X.Z, Kiselev, E, Tropea, J.E, Needle, D, Pommier, Y, Burke, T.R, Waugh, D.S. | | Deposit date: | 2020-03-19 | | Release date: | 2021-03-24 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.489 Å) | | Cite: | Tdp1 catalytic domain
To Be Published
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5AIQ
 | | Crystal structure of ligand-free NadR | | Descriptor: | TRANSCRIPTIONAL REGULATOR, MARR FAMILY | | Authors: | Liguori, A, Malito, E, Bottomley, M.J. | | Deposit date: | 2015-02-16 | | Release date: | 2016-03-02 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.716 Å) | | Cite: | Molecular Basis of Ligand-Dependent Regulation of Nadr, the Transcriptional Repressor of Meningococcal Virulence Factor Nada.
Plos Pathog., 12, 2016
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5AIP
 | | Crystal structure of NadR in complex with 4-hydroxyphenylacetate | | Descriptor: | 4-HYDROXYPHENYLACETATE, TRANSCRIPTIONAL REGULATOR, MARR FAMILY | | Authors: | Liguori, A, Malito, E, Bottomley, M.J. | | Deposit date: | 2015-02-16 | | Release date: | 2016-03-02 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Molecular Basis of Ligand-Dependent Regulation of Nadr, the Transcriptional Repressor of Meningococcal Virulence Factor Nada.
Plos Pathog., 12, 2016
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4JG3
 | | Crystal structure of catabolite repression control protein (crc) from Pseudomonas aeruginosa | | Descriptor: | CHLORIDE ION, Catabolite repression control protein | | Authors: | Grishkovskaya, I, Milojevic, T, Sonnleitner, E, Blaesi, U, Djinovic-Carugo, K. | | Deposit date: | 2013-02-28 | | Release date: | 2013-06-26 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The Pseudomonas aeruginosa Catabolite Repression Control Protein Crc Is Devoid of RNA Binding Activity
Plos One, 8, 2013
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5NHY
 | | BAY-707 in complex with MTH1 | | Descriptor: | 7,8-dihydro-8-oxoguanine triphosphatase, GLYCEROL, SULFATE ION, ... | | Authors: | Ellermann, M, Eheim, A, Giese, A, Bunse, S, Nowak-Reppel, K, Neuhaus, R, Weiske, J, Quanz, M, Glasauer, A, Meyer, H, Queisser, N, Irlbacher, H, Bader, B, Rahm, F, Viklund, J, Andersson, M, Ericsson, U, Ginman, T, Forsblom, R, Lindstrom, J, Silvander, C, Tresaugues, L, Gorjanacz, M. | | Deposit date: | 2017-03-22 | | Release date: | 2017-07-19 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.72 Å) | | Cite: | Novel Class of Potent and Cellularly Active Inhibitors Devalidates MTH1 as Broad-Spectrum Cancer Target.
ACS Chem. Biol., 12, 2017
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4ZHN
 | | Crystal Structure of AlkB T208A mutant protein in complex with Co(II), 2-oxoglutarate, and methylated trinucleotide T-meA-T | | Descriptor: | 2-OXOGLUTARIC ACID, Alpha-ketoglutarate-dependent dioxygenase AlkB, COBALT (II) ION, ... | | Authors: | Ergel, B, Yu, B, Vorobiev, S.M, Forouhar, F, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2015-04-25 | | Release date: | 2015-12-23 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.333 Å) | | Cite: | DFT Studies of the Rate-Limiting Step in the Reaction Cycle of the Fe/2OG Dioxygenase AlkB and Related Experimental Studies
To be published
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7EWE
 | | Mycobacterium tuberculosis HigA2 (Form III) | | Descriptor: | Putative antitoxin HigA2 | | Authors: | Kim, H.J. | | Deposit date: | 2021-05-25 | | Release date: | 2022-03-02 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.41 Å) | | Cite: | Chasing the structural diversity of the transcription regulator Mycobacterium tuberculosis HigA2.
Iucrj, 8, 2021
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7EWD
 | | Mycobacterium tuberculosis HigA2 (Form II) | | Descriptor: | Putative antitoxin HigA2 | | Authors: | Kim, H.J. | | Deposit date: | 2021-05-25 | | Release date: | 2022-03-02 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Chasing the structural diversity of the transcription regulator Mycobacterium tuberculosis HigA2.
Iucrj, 8, 2021
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7EWC
 | | Mycobacterium tuberculosis HigA2 (Form I) | | Descriptor: | Putative antitoxin HigA2 | | Authors: | Kim, H.J. | | Deposit date: | 2021-05-25 | | Release date: | 2022-03-02 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Chasing the structural diversity of the transcription regulator Mycobacterium tuberculosis HigA2.
Iucrj, 8, 2021
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5HYZ
 | | Crystal Structure of SCL7 in Oryza sativa | | Descriptor: | GRAS family transcription factor containing protein, expressed | | Authors: | Wu, Y, Li, S, Zhao, Y, Sun, L. | | Deposit date: | 2016-02-02 | | Release date: | 2016-04-27 | | Last modified: | 2016-06-29 | | Method: | X-RAY DIFFRACTION (1.822 Å) | | Cite: | Crystal Structure of the GRAS Domain of SCARECROW-LIKE7 in Oryza sativa.
Plant Cell, 28, 2016
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4Z58
 | | HipB-O3 20mer complex | | Descriptor: | Antitoxin HipB, DNA (5'-D(*TP*TP*AP*TP*CP*CP*GP*CP*TP*CP*TP*AP*CP*GP*GP*GP*AP*TP*AP*A)-3') | | Authors: | Min, J, Brennan, R.G, Schumacher, M.A. | | Deposit date: | 2015-04-02 | | Release date: | 2016-07-06 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Molecular mechanism on hipBA gene regulation.
To be published
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7ROZ
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