4ZHN

Crystal Structure of AlkB T208A mutant protein in complex with Co(II), 2-oxoglutarate, and methylated trinucleotide T-meA-T

Summary for 4ZHN

• Entry DOI: 10.2210/pdb4zhn/pdb
• Descriptor: methylated trinucleotide DNA T-meA-T, Alpha-ketoglutarate-dependent dioxygenase AlkB, COBALT (II) ION, ... (5 entities in total)
• Functional Keywords: beta jellyroll, oxidoreductase-dna complex, dna repair enzyme, structural genomics, psi-2, protein structure initiative, northeast structural genomics consortium, nesg, oxidoreductase/dna
• Biological source: Escherichia coli (strain K12); More
• Total number of polymer chains: 2
• Total formula weight: 24677.65

Authors

Ergel, B.,Yu, B.,Vorobiev, S.M.,Forouhar, F.,Hunt, J.F.,Northeast Structural Genomics Consortium (NESG) (deposition date: 2015-04-25, release date: 2015-12-23, Last modification date: 2023-09-27)

• Primary citation: Hall, M.L.,Ergel, B.,Miller, E.B.,Yu, B.,Rinaldo, D.,Hunt, J.F.,Friesner, R.; DFT Studies of the Rate-Limiting Step in the Reaction Cycle of the Fe/2OG Dioxygenase AlkB and Related Experimental Studies; To be published,

Experimental method

X-RAY DIFFRACTION (1.333 Å)