4ZHN
Crystal Structure of AlkB T208A mutant protein in complex with Co(II), 2-oxoglutarate, and methylated trinucleotide T-meA-T
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B | methylated trinucleotide DNA T-meA-T | polymer | 3 | 891.7 | 1 | synthetic construct | ||
2 | A | Alpha-ketoglutarate-dependent dioxygenase AlkB | polymer | 211 | 23580.9 | 1 | UniProt (P05050) In PDB | Escherichia coli (strain K12) | Alkylated DNA repair protein AlkB,DNA oxidative demethylase AlkB |
3 | A | COBALT (II) ION | non-polymer | 58.9 | 1 | Chemie (CO) | |||
4 | A | 2-OXOGLUTARIC ACID | non-polymer | 146.1 | 1 | Chemie (AKG) | |||
5 | water | water | 18.0 | 250 | Chemie (HOH) |
Sequence modifications
A: 12 - 216 (UniProt: P05050)
PDB | External Database | Details |
---|---|---|
Met 11 | - | expression tag |
Ala 208 | Thr 208 | engineered mutation |
Asn 217 | - | expression tag |
Leu 218 | - | expression tag |
Tyr 219 | - | expression tag |
Phe 220 | - | expression tag |
Gln 221 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 24472.6 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 205.0 | |
All* | Total formula weight | 24677.6 |