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1E1Y
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Flavopiridol inhibits glycogen phosphorylase by binding at the inhibitor site
Descriptor: 2-(2-CHLORO-PHENYL)-5,7-DIHYDROXY-8-(3-HYDROXY-1-METHYL-PIPERIDIN-4-YL)-4H-BENZOPYRAN-4-ONE, GLYCOGEN PHOSPHORYLASE, MUSCLE FORM, ...
Authors:Oikonomakos, N.G, Zographos, S.E, Skamnaki, V.T, Tsitsanou, K.E, Johnson, L.N.
Deposit date:2000-05-11
Release date:2000-05-17
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Flavopiridol Inhibits Glycogen Phosphorylase by Binding at the Inhibitor Site
J.Biol.Chem., 275, 2000
3ZL6
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Native structure of Farnesyl Pyrophosphate Synthase from Pseudomonas aeruginosa PAO1, with bound fragment KM10833.
Descriptor: 2-(1,2-benzoxazol-3-yl)ethanoic acid, DIMETHYL SULFOXIDE, GERANYLTRANSTRANSFERASE, ...
Authors:Schmidberger, J.W, Schnell, R, Schneider, G.
Deposit date:2013-01-28
Release date:2014-02-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural Characterization of Substrate and Inhibitor Binding to Farnesyl Pyrophosphate Synthase from Pseudomonas Aeruginosa.
Acta Crystallogr.,Sect.D, 71, 2015
3ZMC
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Native structure of Farnesyl Pyrophosphate Synthase from Pseudomonas aeruginosa PA01, with bound substrate molecule Geranyl pyrophosphate.
Descriptor: DIMETHYL SULFOXIDE, GERANYL DIPHOSPHATE, GERANYLTRANSTRANSFERASE, ...
Authors:Schmidberger, J.W, Schnell, R, Schneider, G.
Deposit date:2013-02-07
Release date:2014-02-26
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Structural Characterization of Substrate and Inhibitor Binding to Farnesyl Pyrophosphate Synthase from Pseudomonas Aeruginosa
Acta Crystallogr.,Sect.D, 71, 2015
1NOJ
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COMPLEX OF GLYCOGEN PHOSPHORYLASE WITH A TRANSITION STATE ANALOGUE NOJIRIMYCIN TETRAZOLE AND PHOSPHATE IN THE T STATE
Descriptor: GLYCOGEN PHOSPHORYLASE, NOJIRIMYCINE TETRAZOLE, PHOSPHATE ION, ...
Authors:Johnson, L.N, Mitchell, E.P.
Deposit date:1996-03-12
Release date:1996-07-11
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Ternary complex crystal structures of glycogen phosphorylase with the transition state analogue nojirimycin tetrazole and phosphate in the T and R states.
Biochemistry, 35, 1996
1NOI
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COMPLEX OF GLYCOGEN PHOSPHORYLASE WITH A TRANSITION STATE ANALOGUE NOJIRIMYCIN TETRAZOLE AND PHOSPHATE IN THE T AND R STATES
Descriptor: GLYCOGEN PHOSPHORYLASE, NOJIRIMYCINE TETRAZOLE, PHOSPHATE ION, ...
Authors:Johnson, L.N, Mitchell, E.P.
Deposit date:1996-03-12
Release date:1996-08-01
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Ternary complex crystal structures of glycogen phosphorylase with the transition state analogue nojirimycin tetrazole and phosphate in the T and R states.
Biochemistry, 35, 1996
1NOK
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BU of 1nok by Molmil
COMPLEX OF GLYCOGEN PHOSPHORYLASE WITH A TRANSITION STATE ANALOGUE NOJIRIMYCIN TETRAZOLE AND PHOSPHATE IN THE T STATE
Descriptor: GLYCOGEN PHOSPHORYLASE, NOJIRIMYCINE TETRAZOLE, PYRIDOXAL-5'-PHOSPHATE
Authors:Johnson, L.N, Mitchell, E.P.
Deposit date:1996-03-12
Release date:1996-07-11
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Ternary complex crystal structures of glycogen phosphorylase with the transition state analogue nojirimycin tetrazole and phosphate in the T and R states.
Biochemistry, 35, 1996
1P4G
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BU of 1p4g by Molmil
Crystal structure of glycogen phosphorylase b in complex with C-(1-azido-alpha-D-glucopyranosyl)formamide
Descriptor: C-(1-AZIDO-ALPHA-D-GLUCOPYRANOSYL) FORMAMIDE, Glycogen phosphorylase, muscle form, ...
Authors:Chrysina, E.D, Oikonomakos, N.G, Zographos, S.E, Kosmopoulou, M.N, Bischler, N, Leonidas, D.D, Nagy, V, Somsak, L, Gergely, P, Praly, J.-P.
Deposit date:2003-04-23
Release date:2004-05-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crsytallographic Studies on alpha- and beta-D-glucopyranosyl Formamide Analogues, Inhibitors of Glycogen Phosphorylase
Biocatal.Biotransfor., 21, 2003
1NUH
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BU of 1nuh by Molmil
The crystal structure of human phosphoglucose isomerase complexed with 5-phosphoarabinonate
Descriptor: 5-PHOSPHOARABINONIC ACID, SULFATE ION, glucose phosphate isomerase
Authors:Davies, C.
Deposit date:2003-01-31
Release date:2003-02-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:The structure of human phosphoglucose isomerase complexed with a transition-state analogue.
Acta Crystallogr.,Sect.D, 59, 2003
3ZCT
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Rabbit muscle glycogen phosphorylase b in complex with N-(2-naphthoyl) -N-beta-D-glucopyranosyl urea determined at 2.0 A resolution
Descriptor: GLYCOGEN PHOSPHORYLASE, MUSCLE FORM, INOSINIC ACID, ...
Authors:Chrysina, E.D, Nagy, V, Felfoldi, N, Konya, B, Telepo, K, Praly, J.P, Docsa, T, Gergely, P, Alexacou, K.M, Hayes, J.M, Konstantakaki, M, Kardakaris, R, Leonidas, D.D, Zographos, S.E, Oikonomakos, N.G, Somsak, L.
Deposit date:2012-11-21
Release date:2013-12-11
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Synthesis, Kinetic, Computational and Crystallographic Evaluation of N-Acyl-N-Beta-D- Glucopyranosyl)Ureas, Nanomolar Glucose Analogue Inhibitors of Glycogen Phosphorylase, Potential Antidiabetic Agents
To be Published
3ZCD
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Native structure of Farnesyl Pyrophosphate Synthase from Pseudomonas aeruginosa PA01.
Descriptor: GERANYLTRANSTRANSFERASE
Authors:Schmidberger, J.W, Schnell, R, Schneider, G.
Deposit date:2012-11-19
Release date:2013-12-04
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural Characterization of Substrate and Inhibitor Binding to Farnesyl Pyrophosphate Synthase from Pseudomonas Aeruginosa.
Acta Crystallogr.,Sect.D, 71, 2015
3ZCS
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BU of 3zcs by Molmil
Rabbit muscle glycogen phosphorylase b in complex with N-(1-naphthoyl) -N-beta-D-glucopyranosyl urea determined at 2.07 A resolution
Descriptor: GLYCOGEN PHOSPHORYLASE, MUSCLE FORM, INOSINIC ACID, ...
Authors:Chrysina, E.D, Nagy, V, Felfoldi, N, Konya, B, Telepo, K, Praly, J.P, Docsa, T, Gergely, P, Alexacou, K.M, Hayes, J.M, Konstantakaki, M, Kardakaris, R, Leonidas, D.D, Zographos, S.E, Oikonomakos, N.G, Somsak, L.
Deposit date:2012-11-21
Release date:2013-12-11
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Synthesis, Kinetic, Computational and Crystallographic Evaluation of N-Acyl-N-Beta-D- Glucopyranosyl)Ureas, Nanomolar Glucose Analogue Inhibitors of Glycogen Phosphorylase, Potential Antidiabetic Agents
To be Published
41BI
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BU of 41bi by Molmil
INTERLEUKIN-1 BETA (IL-1 BETA) (MUTANT WITH CYS 8 REPLACED BY ALA (C8A)
Descriptor: INTERLEUKIN-1 BETA
Authors:Veerapandian, B, Poulos, T.L, Gilliland, G.L, Masui, Y, Hirai, Y.
Deposit date:1992-02-03
Release date:1992-04-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:

1FA9
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HUMAN LIVER GLYCOGEN PHOSPHORYLASE A COMPLEXED WITH AMP
Descriptor: ADENOSINE MONOPHOSPHATE, GLYCOGEN PHOSPHORYLASE, LIVER FORM, ...
Authors:Rath, V.L, Ammirati, M, LeMotte, P.K, Fennell, K.F, Mansour, M.N, Danley, D.E, Hynes, T.R, Schulte, G.K, Wasilko, D.J, Pandit, J.
Deposit date:2000-07-12
Release date:2000-08-25
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Activation of human liver glycogen phosphorylase by alteration of the secondary structure and packing of the catalytic core.
Mol.Cell, 6, 2000
1P2G
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Crystal Structure of Glycogen Phosphorylase B in complex with Gamma Cyclodextrin
Descriptor: Cyclooctakis-(1-4)-(alpha-D-glucopyranose), Glycogen phosphorylase, muscle form, ...
Authors:Pinotsis, N, Leonidas, D.D, Chrysina, E.D, Oikonomakos, N.G, Mavridis, I.M.
Deposit date:2003-04-15
Release date:2003-09-02
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The binding of beta- and gamma-cyclodextrins to glycogen phosphorylase b: Kinetic and crystallographic studies.
Protein Sci., 12, 2003
1MKK
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BU of 1mkk by Molmil
Disulfide deficient mutant of vascular endothelial growth factor A (C61A and C104A)
Descriptor: Vascular Endothelial Growth Factor A
Authors:Muller, Y.A, Heiring, C, Misselwitz, R, Welfle, K, Welfle, H.
Deposit date:2002-08-29
Release date:2002-12-11
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:The cystine knot promotes folding and not thermodynamic stability in vascular endothelial growth factor
J.Biol.Chem., 277, 2002
1MKG
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BU of 1mkg by Molmil
DISULFIDE DEFICIENT MUTANT OF VASCULAR ENDOTHELIAL GROWTH FACTOR A (C57A and C102A)
Descriptor: Vascular Endothelial Growth Factor A
Authors:Muller, Y.A, Heiring, C, Misselwitz, R, Welfle, K, Welfle, H.
Deposit date:2002-08-29
Release date:2002-12-11
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The cystine knot promotes folding and not thermodynamic stability in vascular endothelial growth factor
J.Biol.Chem., 277, 2002
1EXV
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BU of 1exv by Molmil
HUMAN LIVER GLYCOGEN PHOSPHORYLASE A COMPLEXED WITH GLCNAC AND CP-403,700
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, LIVER GLYCOGEN PHOSPHORYLASE, N-acetyl-beta-D-glucopyranosylamine, ...
Authors:Rath, V.L, Ammirati, M, Danley, D.E, Ekstrom, J.L, Hynes, T.R, Olson, T.V, Hoover, D.J.
Deposit date:2000-05-04
Release date:2000-11-01
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Human liver glycogen phosphorylase inhibitors bind at a new allosteric site.
Chem.Biol., 7, 2000
1FC0
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BU of 1fc0 by Molmil
HUMAN LIVER GLYCOGEN PHOSPHORYLASE COMPLEXED WITH N-ACETYL-BETA-D-GLUCOPYRANOSYLAMINE
Descriptor: GLYCOGEN PHOSPHORYLASE, LIVER FORM, N-acetyl-beta-D-glucopyranosylamine, ...
Authors:Rath, V.L, Ammirati, M, LeMotte, P.K, Fennell, K.F, Mansour, M.M, Danley, D.E, Hynes, T.R, Schulte, G.K, Wasilko, D.J, Pandit, J.
Deposit date:2000-07-17
Release date:2000-08-25
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Activation of human liver glycogen phosphorylase by alteration of the secondary structure and packing of the catalytic core.
Mol.Cell, 6, 2000
1P29
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BU of 1p29 by Molmil
Crystal Structure of glycogen phosphorylase b in complex with maltopentaose
Descriptor: Glycogen phosphorylase, muscle form, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Pinotsis, N, Leonidas, D.D, Chrysina, E.D, Oikonomakos, N.G, Mavridis, I.M.
Deposit date:2003-04-15
Release date:2003-09-02
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The binding of beta- and gamma-cyclodextrins to glycogen phosphorylase b: Kinetic and crystallographic studies.
Protein Sci., 12, 2003
4BQF
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BU of 4bqf by Molmil
Arabidopsis thaliana cytosolic alpha-1,4-glucan phosphorylase (PHS2) in complex with acarbose
Descriptor: 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose, ALPHA-GLUCAN PHOSPHORYLASE 2, CYTOSOLIC, ...
Authors:O'Neill, E.C, Rashid, A.M, Stevenson, C.E.M, Hetru, A.C, Gunning, A.P, Rejzek, M, Nepogodiev, S.A, Bornemann, S, Lawson, D.M, Field, R.A.
Deposit date:2013-05-30
Release date:2014-02-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Sugar-Coated Sensor Chip and Nanoparticle Surfaces for the in Vitro Enzymatic Synthesis of Starch-Like Materials
Chem.Sci., 5, 2014
4BQI
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BU of 4bqi by Molmil
ARABIDOPSIS THALIANA cytosolic alpha-1,4-glucan phosphorylase (PHS2) in complex with maltotriose
Descriptor: ALPHA-GLUCAN PHOSPHORYLASE 2, CYTOSOLIC, DI(HYDROXYETHYL)ETHER, ...
Authors:O'Neill, E.C, Rashid, A.M, Stevenson, C.E.M, Hetru, A.C, Gunning, A.P, Rejzek, M, Nepogodiev, S.A, Bornemann, S, Lawson, D.M, Field, R.A.
Deposit date:2013-05-30
Release date:2014-02-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Sugar-Coated Sensor Chip and Nanoparticle Surfaces for the in Vitro Enzymatic Synthesis of Starch-Like Materials
Chem.Sci., 5, 2014
1PDG
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BU of 1pdg by Molmil
CRYSTAL STRUCTURE OF HUMAN PLATELET-DERIVED GROWTH FACTOR BB
Descriptor: PLATELET-DERIVED GROWTH FACTOR BB
Authors:Oefner, C, Darcy, A.D, Winkler, F.K, Eggimann, B, Hosnag, M.
Deposit date:1992-07-14
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of human platelet-derived growth factor BB.
EMBO J., 11, 1992
1N8T
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BU of 1n8t by Molmil
The crystal structure of phosphoglucose isomerase from rabbit muscle
Descriptor: Glucose-6-phosphate isomerase
Authors:Davies, C, Muirhead, H.
Deposit date:2002-11-21
Release date:2003-03-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of native phosphoglucose isomerase from rabbit: conformational changes associated with catalytic function.
Acta Crystallogr.,Sect.D, 59, 2003
1FS4
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BU of 1fs4 by Molmil
Structures of glycogen phosphorylase-inhibitor complexes and the implications for structure-based drug design
Descriptor: 1-DEOXY-1-METHOXYCARBAMIDO-BETA-D-GLUCO-2-HEPTULOPYRANOSONAMIDE, GLYCOGEN PHOSPHORYLASE, PYRIDOXAL-5'-PHOSPHATE
Authors:Watson, K.A, Tsitsanou, K.E, Gregoriou, M, Zographos, S.E, Skamnaki, V.T, Oikonomakos, N.G, Fleet, G.W, Johnson, L.N.
Deposit date:2000-09-08
Release date:2000-10-04
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Kinetic and crystallographic studies of glucopyranose spirohydantoin and glucopyranosylamine analogs inhibitors of glycogen phosphorylase.
Proteins, 61, 2005
1LWO
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BU of 1lwo by Molmil
Crystal structure of rabbit muscle glycogen phosphorylase a in complex with a potential hypoglycaemic drug at 2.0 A resolution
Descriptor: 5-CHLORO-1H-INDOLE-2-CARBOXYLIC ACID [1-(4-FLUOROBENZYL)-2-(4-HYDROXYPIPERIDIN-1YL)-2-OXOETHYL]AMIDE, PYRIDOXAL-5'-PHOSPHATE, alpha-D-glucopyranose, ...
Authors:Oikonomakos, N.G, Chrysina, E.D, Kosmopoulou, M.N, Leonidas, D.D.
Deposit date:2002-06-01
Release date:2002-06-19
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of rabbit muscle glycogen phosphorylase a in complex with a potential hypoglycaemic drug at 2.0 A resolution
BIOCHEM.BIOPHYS.ACTA PROTEINS & PROTEOMICS, 1647, 2003

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数据于2024-08-07公开中

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