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5VEZ
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BU of 5vez by Molmil
DNA polymerase beta substrate complex with 8-oxoG:A at the primer terminus and incoming dCTP analog
Descriptor: 2'-deoxy-5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (5'-D(*CP*CP*GP*AP*CP*GP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(8OG))-3'), ...
Authors:Freudenthal, B.D, Schaich, M.A, Whitaker, A.M, Smith, M.R.
Deposit date:2017-04-06
Release date:2017-05-10
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.039 Å)
Cite:Capturing a mammalian DNA polymerase extending from an oxidized nucleotide.
Nucleic Acids Res., 45, 2017
3HAS
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BU of 3has by Molmil
Crystal structure of bacteriorhodopsin mutant L152A crystallized from bicelles
Descriptor: 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Bacteriorhodopsin, DECANE, ...
Authors:Joh, N.H, Yang, D, Bowie, J.U.
Deposit date:2009-05-02
Release date:2009-09-22
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Similar energetic contributions of packing in the core of membrane and water-soluble proteins.
J.Am.Chem.Soc., 131, 2009
4W2G
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BU of 4w2g by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with pactamycin (soaked), mRNA and three deacylated tRNAs in the A, P and E sites
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
Authors:Polikanov, Y.S, Osterman, I.A, Szal, T, Tashlitsky, V.N, Serebryakova, M.V, Kusochek, P, Bulkley, D, Malanicheva, I.A, Efimenko, T.A, Efremenkova, O.V, Konevega, A.L, Shaw, K.J, Bogdanov, A.A, Rodnina, M.V, Dontsova, O.A, Mankin, A.S, Steitz, T.A, Sergiev, P.V.
Deposit date:2014-09-12
Release date:2014-10-15
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome.
Mol.Cell, 56, 2014
4V9A
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BU of 4v9a by Molmil
Crystal Structure of the 70S ribosome with tetracycline.
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Jenner, L, Yusupov, M, Yusupova, G.
Deposit date:2012-07-18
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.2999 Å)
Cite:Structural basis for potent inhibitory activity of the antibiotic tigecycline during protein synthesis.
Proc.Natl.Acad.Sci.USA, 110, 2013
1N2N
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BU of 1n2n by Molmil
Crystal structure of cyanide complex of the oxygenase domain of inducible nitric oxide synthase.
Descriptor: 5,6,7,8-TETRAHYDROBIOPTERIN, ARGININE, CYANIDE ION, ...
Authors:Fedorov, R, Ghosh, D.K, Schlichting, I.
Deposit date:2002-10-23
Release date:2003-02-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of cyanide complexes of P450cam and the oxygenase domain of inducible nitric oxide synthase-structural models of the short-lived oxygen complexes
Arch.Biochem.Biophys., 409, 2003
4W7Y
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BU of 4w7y by Molmil
Dimeric BAP29 vDED with disulfide bonds in crystal contacts
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, B-cell receptor-associated protein 29
Authors:Quistgaard, E.M.
Deposit date:2014-08-22
Release date:2014-10-29
Last modified:2014-11-19
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A disulfide polymerized protein crystal.
Chem.Commun.(Camb.), 50, 2014
5VIU
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BU of 5viu by Molmil
Crystal Structure of Acetylornithine Aminotransferase from Elizabethkingia anophelis
Descriptor: 1,2-ETHANEDIOL, Acetylornithine aminotransferase, CITRIC ACID
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2017-04-17
Release date:2017-05-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal Structure of Acetylornithine Aminotransferase from Elizabethkingia anophelis
to be published
4US7
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BU of 4us7 by Molmil
Sulfur SAD Phased Structure of a Type IV Pilus Protein from Shewanella oneidensis
Descriptor: PILD PROCESSED PROTEIN, SODIUM ION, SULFATE ION
Authors:Gorgel, M, Boeggild, A, Ulstrup, J.J, Mueller, U, Weiss, M, Nissen, P, Boesen, T.
Deposit date:2014-07-03
Release date:2015-04-29
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:High-Resolution Structure of a Type Iv Pilin from the Metal- Reducing Bacterium Shewanella Oneidensis.
Bmc Struct.Biol., 15, 2015
4V0O
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BU of 4v0o by Molmil
Crystal structure of BBS1N in complex with ARL6DN, soaked with lead
Descriptor: ARF-LIKE SMALL GTPASE, BARDET-BIEDL SYNDROME 1 PROTEIN, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Mourao, A, Lorentzen, E.
Deposit date:2014-09-17
Release date:2014-11-19
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.351 Å)
Cite:Structural Basis for Membrane Targeting of the Bbsome by Arl6
Nat.Struct.Mol.Biol., 21, 2014
5VML
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BU of 5vml by Molmil
Crystal Structure of Acetoacetyl-CoA Reductase from Burkholderia Pseudomallei 1710b with bound NADP
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Acetoacetyl-CoA reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2017-04-27
Release date:2017-05-24
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of Acetoacetyl-CoA Reductase from Burkholderia Pseudomallei 1710b with bound NADP
to be published
5VPR
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BU of 5vpr by Molmil
Crystal Structure of Cysteine desulfurase from Elizabethkingia anophelis with covalently bound pyridoxal phosphate
Descriptor: Cysteine desulfurase
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2017-05-05
Release date:2017-05-17
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal Structure of Cysteine desulfurase from Elizabethkingia anophelis with covalently bound pyridoxal phosphate
to be published
4V7T
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BU of 4v7t by Molmil
Crystal structure of the E. coli ribosome bound to chloramphenicol.
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Dunkle, J.A, Xiong, L, Mankin, A.S, Cate, J.H.D.
Deposit date:2010-08-14
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.1942 Å)
Cite:Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action.
Proc.Natl.Acad.Sci.USA, 107, 2010
5VF9
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BU of 5vf9 by Molmil
Native human manganese superoxide dismutase
Descriptor: MANGANESE (II) ION, PHOSPHATE ION, POTASSIUM ION, ...
Authors:Azadmanesh, J, Trickel, S.R, Borgstahl, G.E.O.
Deposit date:2017-04-07
Release date:2017-05-17
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Substrate-analog binding and electrostatic surfaces of human manganese superoxide dismutase.
J. Struct. Biol., 199, 2017
9ASK
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BU of 9ask by Molmil
Human DNA polymerase theta helicase domain dimer, apo-form
Descriptor: DNA polymerase theta
Authors:Ito, F, Li, Z, Chen, X.S.
Deposit date:2024-02-26
Release date:2024-06-26
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural Basis for Pol theta-Helicase DNA Binding and Microhomology-Mediated End-Joining.
Biorxiv, 2024
5VGB
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BU of 5vgb by Molmil
Crystal structure of NmeCas9 HNH domain bound to anti-CRISPR AcrIIC1
Descriptor: Anti-CRISPR protein (AcrIIC1), CRISPR-associated endonuclease Cas9, GLYCEROL, ...
Authors:Harrington, L.B, Doxzen, K.W, Ma, E, Knott, G.J, Kranzusch, P.J, Doudna, J.A.
Deposit date:2017-04-10
Release date:2017-08-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.497 Å)
Cite:A Broad-Spectrum Inhibitor of CRISPR-Cas9.
Cell, 170, 2017
4V7S
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BU of 4v7s by Molmil
Crystal structure of the E. coli ribosome bound to telithromycin.
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Dunkle, J.A, Xiong, L, Mankin, A.S, Cate, J.H.D.
Deposit date:2010-08-05
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.2547 Å)
Cite:Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action.
Proc.Natl.Acad.Sci.USA, 107, 2010
1VQW
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BU of 1vqw by Molmil
Crystal structure of a protein with similarity to flavin-containing monooxygenases and to mammalian dimethylalanine monooxygenases
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, PROTEIN WITH SIMILARITY TO FLAVIN-CONTAINING MONOOXYGENASES AND TO MAMMALIAN DIMETHYLALANINE MONOOXYGENASES
Authors:Eswaramoorthy, S, Swaminathan, S, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2005-01-05
Release date:2005-01-11
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Mechanism of action of a flavin-containing monooxygenase.
Proc.Natl.Acad.Sci.Usa, 103, 2006
9ASL
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BU of 9asl by Molmil
Human DNA polymerase theta helicase domain tetramer, apo-form
Descriptor: DNA polymerase theta
Authors:Ito, F, Li, Z, Chen, X.S.
Deposit date:2024-02-26
Release date:2024-06-26
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural Basis for Pol theta-Helicase DNA Binding and Microhomology-Mediated End-Joining.
Biorxiv, 2024
4FMD
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BU of 4fmd by Molmil
EspG-Rab1 complex structure at 3.05 A
Descriptor: ALUMINUM FLUORIDE, DI(HYDROXYETHYL)ETHER, EspG protein, ...
Authors:Shao, F, Zhu, Y.
Deposit date:2012-06-16
Release date:2012-09-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structurally Distinct Bacterial TBC-like GAPs Link Arf GTPase to Rab1 Inactivation to Counteract Host Defenses.
Cell(Cambridge,Mass.), 150, 2012
4UVQ
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BU of 4uvq by Molmil
PatG Domain of Unknown Function
Descriptor: THIAZOLINE OXIDASE/SUBTILISIN-LIKE PROTEASE, ZINC ION
Authors:Mann, G, Koehnke, J, Bent, A.F, Graham, R, Schwarz-Linek, U, Naismith, J.H.
Deposit date:2014-08-07
Release date:2014-09-17
Last modified:2014-12-17
Method:X-RAY DIFFRACTION (1.724 Å)
Cite:The Structure of the Cyanobactin Domain of Unknown Function from Patg in the Patellamide Gene Cluster
Acta Crystallogr.,Sect.F, 70, 2014
4UW2
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BU of 4uw2 by Molmil
Crystal structure of Csm1 in T.onnurineus
Descriptor: CSM1
Authors:Jung, T.Y, An, Y, Park, K.H, Lee, M.H, Oh, B.H, Woo, E.J.
Deposit date:2014-08-08
Release date:2015-03-25
Last modified:2015-09-23
Method:X-RAY DIFFRACTION (2.632 Å)
Cite:Crystal Structure of the Csm1 Subunit of the Csm Complex and its Single-Stranded DNA-Specific Nuclease Activity.
Structure, 23, 2015
7LGS
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BU of 7lgs by Molmil
Structure of EGFR_D770_N771insNPG/V948R in complex with covalent inhibitor Osimertinib.
Descriptor: 1,2-ETHANEDIOL, CITRIC ACID, Epidermal growth factor receptor, ...
Authors:Skene, R.J, Lane, W.
Deposit date:2021-01-21
Release date:2021-09-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Mobocertinib (TAK-788): A Targeted Inhibitor of EGFR Exon 20 Insertion Mutants in Non-Small Cell Lung Cancer.
Cancer Discov, 11, 2021
4UZ0
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BU of 4uz0 by Molmil
Crystal Structure of apoptosis repressor with CARD (ARC)
Descriptor: GLYCEROL, NUCLEOLAR PROTEIN 3
Authors:Kim, S.H, Jeong, J.H, Jang, T.H, Kim, Y.G, Park, H.H.
Deposit date:2014-09-04
Release date:2015-07-01
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (2.399 Å)
Cite:Crystal Structure of Caspase Recruiting Domain (Card) of Apoptosis Repressor with Card (Arc) and its Implication in Inhibition of Apoptosis.
Sci.Rep., 5, 2015
9ASJ
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BU of 9asj by Molmil
Human DNA polymerase theta helicase domain in complex with AMP-PNP, dimer form
Descriptor: DNA polymerase theta, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Ito, F, Li, Z, Chen, X.S.
Deposit date:2024-02-26
Release date:2024-06-26
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural Basis for Pol theta-Helicase DNA Binding and Microhomology-Mediated End-Joining.
Biorxiv, 2024
1W9B
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BU of 1w9b by Molmil
S. alba myrosinase in complex with carba-glucotropaeolin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBA-GLUCOTROPAEOLIN, ...
Authors:Bourderioux, A, Lefoix, M, Gueyrard, D, Tatibouet, A, Cottaz, S, Arzt, S, Burmeister, W.P, Rollin, P.
Deposit date:2004-10-08
Release date:2005-05-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The glucosinolate-myrosinase system. New insights into enzyme-substrate interactions by use of simplified inhibitors.
Org. Biomol. Chem., 3, 2005

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数据于2024-07-10公开中

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