4H0E
| Crystal Structure of mutant ORR3 in complex with NTD of AraR | Descriptor: | 5'-D(*AP*AP*AP*TP*TP*TP*GP*TP*CP*CP*GP*TP*AP*CP*AP*TP*TP*TP*TP*AP*T)-3', 5'-D(*TP*AP*TP*AP*AP*AP*AP*TP*GP*TP*AP*CP*GP*GP*AP*CP*AP*AP*AP*TP*T)-3', ACETATE ION, ... | Authors: | Nair, D.T, Jain, D. | Deposit date: | 2012-09-08 | Release date: | 2013-02-06 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.973 Å) | Cite: | Spacing between core recognition motifs determines relative orientation of AraR monomers on bipartite operators. Nucleic Acids Res., 41, 2013
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5ZZ7
| Redox-sensing transcriptional repressor Rex | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, GLYCEROL, Redox-sensing transcriptional repressor Rex 1 | Authors: | Park, Y.W, Jang, Y.Y, Joo, H.K, Lee, J.Y. | Deposit date: | 2018-05-30 | Release date: | 2018-11-07 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structural Analysis of Redox-sensing Transcriptional Repressor Rex from Thermotoga maritima Sci Rep, 8, 2018
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2ZCW
| Crystal Structure of TTHA1359, a Transcriptional Regulator, CRP/FNR family from Thermus thermophilus HB8 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Transcriptional regulator, FNR/CRP family | Authors: | Agari, Y, Yokoyama, S, Kuramitsu, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-11-13 | Release date: | 2007-12-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Global gene expression mediated by Thermus thermophilus SdrP, a CRP/FNR family transcriptional regulator Mol.Microbiol., 70, 2008
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3WG9
| Crystal structure of RSP, a Rex-family repressor | Descriptor: | Redox-sensing transcriptional repressor rex, SULFATE ION | Authors: | Zheng, Y, Ko, T.-P, Guo, R.-T. | Deposit date: | 2013-08-03 | Release date: | 2014-08-13 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Distinct structural features of Rex-family repressors to sense redox levels in anaerobes and aerobes. J.Struct.Biol., 188, 2014
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4R79
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6UXV
| SWI/SNF Body Module | Descriptor: | SWI/SNF chromatin-remodeling complex subunit SNF5, SWI/SNF chromatin-remodeling complex subunit SWI1, SWI/SNF complex subunit SWI3, ... | Authors: | He, Y, Han, Y. | Deposit date: | 2019-11-08 | Release date: | 2020-03-18 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Cryo-EM structure of SWI/SNF complex bound to a nucleosome. Nature, 579, 2020
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7X2Z
| NMR solution structure of the 1:1 complex of a pyridostatin derivative (PyPDS) bound to a G-quadruplex MYT1L | Descriptor: | 4-(2-azanylethoxy)-N2,N6-bis[4-(2-pyrrolidin-1-ylethoxy)quinolin-2-yl]pyridine-2,6-dicarboxamide, G-quadruplex DNA MYT1L | Authors: | Liu, L.-Y, Mao, Z.-W, Liu, W. | Deposit date: | 2022-02-26 | Release date: | 2022-06-08 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural Basis of Pyridostatin and Its Derivatives Specifically Binding to G-Quadruplexes. J.Am.Chem.Soc., 144, 2022
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5MAV
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4BXX
| Arrested RNA polymerase II-Bye1 complex | Descriptor: | 5'-D(*AP*GP*CP*TP*AP*GP*CP*TP*TP*AP*CP*CP*TP*GP *GP*TP*GP* BRUP*TP*GP*CP*TP*CP*TP*AP*AP*DC)-3', 5'-D(*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP)-3', 5'-D(*GP*AP*GP*GP*TP*AP*AP*GP*CP*TP*AP*GP*CP*TP)-3', ... | Authors: | Kinkelin, K, Wozniak, G.G, Rothbart, S.B, Lidschreiber, M, Strahl, B.D, Cramer, P. | Deposit date: | 2013-07-16 | Release date: | 2013-09-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.28 Å) | Cite: | Structures of RNA Polymerase II Complexes with Bye1, a Chromatin-Binding Phf3/Dido1 Homologue Proc.Natl.Acad.Sci.USA, 110, 2013
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5K98
| Structure of HipA-HipB-O2-O3 complex | Descriptor: | Antitoxin HipB, DNA (5'-D(*CP*TP*AP*TP*CP*CP*CP*CP*TP*TP*AP*AP*GP*GP*GP*GP*AP*TP*AP*GP*GP*GP*A)-3'), DNA (5'-D(*TP*CP*CP*CP*TP*AP*TP*CP*CP*CP*CP*TP*TP*AP*AP*GP*GP*GP*GP*AP*TP*AP*G)-3'), ... | Authors: | Schumacher, M. | Deposit date: | 2016-05-31 | Release date: | 2016-06-22 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.99 Å) | Cite: | HipBA-promoter structures reveal the basis of heritable multidrug tolerance. Nature, 524, 2015
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2CAJ
| NikR from Helicobacter pylori in closed trans-conformation and nickel bound to 4 intermediary sites | Descriptor: | CHLORIDE ION, GLYCEROL, NICKEL (II) ION, ... | Authors: | Dian, C, Schauer, K, Kapp, U, McSweeney, S.M, Labigne, A, Terradot, L. | Deposit date: | 2005-12-21 | Release date: | 2006-07-17 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural Basis of the Nickel Response in Helicobacter Pylori: Crystal Structures of Hpnikr in Apo and Nickel-Bound States. J.Mol.Biol., 361, 2006
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2CA9
| apo-NIKR from helicobacter pylori in closed trans-conformation | Descriptor: | FORMIC ACID, GLYCEROL, PUTATIVE NICKEL-RESPONSIVE REGULATOR | Authors: | Dian, C, Schauer, K, Kapp, U, McSweeney, S.M, Labigne, A, Terradot, L. | Deposit date: | 2005-12-20 | Release date: | 2006-07-17 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural Basis of the Nickel Response in Helicobacter Pylori: Crystal Structures of Hpnikr in Apo and Nickel-Bound States. J.Mol.Biol., 361, 2006
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2CAD
| NikR from Helicobacter pylori in closed trans-conformation and nickel bound to 2F, 2X and 2I sites. | Descriptor: | CITRIC ACID, FORMIC ACID, GLYCEROL, ... | Authors: | Dian, C, Schauer, K, Kapp, U, McSweeney, S.M, Labigne, A, Terradot, L. | Deposit date: | 2005-12-20 | Release date: | 2006-07-17 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Basis of the Nickel Response in Helicobacter Pylori: Crystal Structures of Hpnikr in Apo and Nickel-Bound States. J.Mol.Biol., 361, 2006
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4U6N
| Crystal structure of Escherichia coli DiaA | Descriptor: | CHLORIDE ION, DnaA initiator-associating protein DiaA | Authors: | Oakley, A.J, Lo, T. | Deposit date: | 2014-07-29 | Release date: | 2014-08-06 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Crystal structure of Escherichia coli DiaA To Be Published
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3TP0
| Structural activation of the transcriptional repressor EthR from M. tuberculosis by single amino-acid change mimicking natural and synthetic ligands | Descriptor: | 3-oxo-3-{4-[3-(thiophen-2-yl)-1,2,4-oxadiazol-5-yl]piperidin-1-yl}propanenitrile, HTH-type transcriptional regulator EthR | Authors: | Carette, X, Blondiaux, N, Willery, E, Hoos, S, Lecat-Guillet, N, Lens, Z, Wohlkonig, A, Wintjens, R, Soror, S, Fr nois, F, Diri, B, Villeret, V, England, P, Lippens, G, Deprez, B, Locht, C, Willand, N, Baulard, A. | Deposit date: | 2011-09-07 | Release date: | 2011-12-21 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural activation of the transcriptional repressor EthR from Mycobacterium tuberculosis by single amino acid change mimicking natural and synthetic ligands. Nucleic Acids Res., 40, 2011
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6ZQB
| Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state B2 | Descriptor: | 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... | Authors: | Cheng, J, Lau, B, Venuta, G.L, Berninghausen, O, Hurt, E, Beckmann, R. | Deposit date: | 2020-07-09 | Release date: | 2020-09-23 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | 90 S pre-ribosome transformation into the primordial 40 S subunit. Science, 369, 2020
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2F05
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2FX0
| Crystal Structure of HlyIIR, a Hemolysin II transcriptional Regulator | Descriptor: | hemolysin II regulatory protein | Authors: | Kovalevskiy, O.V, Lebedev, A.A, Solonin, A.S, Antson, A.A. | Deposit date: | 2006-02-03 | Release date: | 2006-02-21 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structure of Bacillus cereus HlyIIR, a Transcriptional Regulator of the Gene for Pore-forming Toxin Hemolysin II. J.Mol.Biol., 365, 2007
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2C9N
| Structure of the Epstein-Barr virus ZEBRA protein at approximately 3. 5 Angstrom resolution | Descriptor: | 5'-D(*CP*AP*CP*TP*GP*AP*CP*TP*CP*AP *T)-3', 5'-D(*CP*AP*TP*GP*AP*GP*TP*CP*AP*GP *T)-3', BZLF1 TRANS-ACTIVATOR PROTEIN | Authors: | Petosa, C, Morand, P, Baudin, F, Moulin, M, Artero, J.B, Muller, C.W. | Deposit date: | 2005-12-13 | Release date: | 2006-02-21 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural Basis of Lytic Cycle Activation by the Epstein-Barr Virus Zebra Protein Mol.Cell, 21, 2006
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4EGY
| Crystal Structure of AraR(DBD) in complex with operator ORA1 | Descriptor: | 5'-D(*AP*AP*AP*AP*TP*TP*GP*TP*TP*CP*GP*TP*AP*CP*AP*AP*AP*TP*AP*TP*T)-3', 5'-D(*TP*AP*AP*TP*AP*TP*TP*TP*GP*TP*AP*CP*GP*AP*AP*CP*AP*AP*TP*TP*T)-3', ACETATE ION, ... | Authors: | Jain, D, Nair, D.T. | Deposit date: | 2012-04-02 | Release date: | 2013-02-06 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.301 Å) | Cite: | Spacing between core recognition motifs determines relative orientation of AraR monomers on bipartite operators. Nucleic Acids Res., 41, 2013
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4UA2
| Crystal structure of dual function transcriptional regulator MerR from Bacillus megaterium MB1 | Descriptor: | Regulatory protein | Authors: | Lin, L.Y, Chang, C.C, Zou, X.W, Huang, C.C, Chan, N.L. | Deposit date: | 2014-08-07 | Release date: | 2015-07-22 | Last modified: | 2020-01-29 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Structural basis of the mercury(II)-mediated conformational switching of the dual-function transcriptional regulator MerR Nucleic Acids Res., 43, 2015
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4UA1
| Crystal structure of dual function transcriptional regulator MerR form Bacillus megaterium MB1 in complex with mercury (II) ion | Descriptor: | MERCURY (II) ION, Regulatory protein | Authors: | Chang, C.C, Lin, L.Y, Zou, X.W, Huang, C.C, Chan, N.L. | Deposit date: | 2014-08-07 | Release date: | 2015-07-22 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.56 Å) | Cite: | Structural basis of the mercury(II)-mediated conformational switching of the dual-function transcriptional regulator MerR Nucleic Acids Res., 43, 2015
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4N0B
| Crystal structure of Bacillus subtilis GabR, an autorepressor and transcriptional activator of GabT | Descriptor: | ACETYL GROUP, CALCIUM ION, HTH-type transcriptional regulatory protein GabR, ... | Authors: | Edayathumangalam, R, Wu, R, Garcia, R, Wang, Y, Wang, W, Kreinbring, C.A, Bach, A, Liao, J, Stone, T, Terwilliger, T, Hoang, Q.Q, Belitsky, B.R, Petsko, G.A, Ringe, D, Liu, D. | Deposit date: | 2013-10-01 | Release date: | 2013-10-30 | Last modified: | 2014-04-02 | Method: | X-RAY DIFFRACTION (2.705 Å) | Cite: | Crystal structure of Bacillus subtilis GabR, an autorepressor and transcriptional activator of gabT. Proc.Natl.Acad.Sci.USA, 110, 2013
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3TP3
| Structure of HTH-type transcriptional regulator EthR, G106W mutant | Descriptor: | HTH-type transcriptional regulator EthR | Authors: | Carette, X. | Deposit date: | 2011-09-07 | Release date: | 2011-12-21 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Structural activation of the transcriptional repressor EthR from Mycobacterium tuberculosis by single amino acid change mimicking natural and synthetic ligands. Nucleic Acids Res., 40, 2011
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6DGC
| Crystal structure of the C-terminal catalytic domain of ISC1926 TnpA, an IS607-like serine recombinase | Descriptor: | ISC1926 TnpA C-terminal catalytic domain | Authors: | Hancock, S.P, Kumar, P, Cascio, D, Johnson, R.C. | Deposit date: | 2018-05-17 | Release date: | 2018-07-18 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.92 Å) | Cite: | Multiple serine transposase dimers assemble the transposon-end synaptic complex during IS607-family transposition. Elife, 7, 2018
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