2CAD

NikR from Helicobacter pylori in closed trans-conformation and nickel bound to 2F, 2X and 2I sites.

Summary for 2CAD

• Entry DOI: 10.2210/pdb2cad/pdb
• Related: 2CA9 2CAJ
• Descriptor: PUTATIVE NICKEL-RESPONSIVE REGULATOR, FORMIC ACID, GLYCEROL, ... (6 entities in total)
• Functional Keywords: nickel uptake, transcription regulator, ribbon-helix-helix, acidic-adaptive response, transcriptional regulation, dna-binding, hypothetical protein, metal-binding, nickel
• Biological source: HELICOBACTER PYLORI
• Total number of polymer chains: 2
• Total formula weight: 35169.13

Authors

Dian, C.,Schauer, K.,Kapp, U.,McSweeney, S.M.,Labigne, A.,Terradot, L. (deposition date: 2005-12-20, release date: 2006-07-17, Last modification date: 2011-07-13)

• Primary citation: Dian, C.,Schauer, K.,Kapp, U.,Mcsweeney, S.M.,Labigne, A.,Terradot, L.; Structural Basis of the Nickel Response in Helicobacter Pylori: Crystal Structures of Hpnikr in Apo and Nickel-Bound States.; J.Mol.Biol., 361:715-, 2006; PubMed: 16872629; DOI: 10.1016/J.JMB.2006.06.058

Experimental method

X-RAY DIFFRACTION (2.3 Å)